Souhel Najjar

Summary

Publications

  1. doi request reprint Neuroinflammation and white matter pathology in schizophrenia: systematic review
    Souhel Najjar
    Neuroinflammation Research Group, Epilepsy Center Division, Department of Neurology, NYU School of Medicine, New York, New York, United States Electronic address
    Schizophr Res 161:102-12. 2015
  2. pmc Neurovascular unit dysfunction with blood-brain barrier hyperpermeability contributes to major depressive disorder: a review of clinical and experimental evidence
    Souhel Najjar
    Department of Neurology, Neuroinflammation Research Group, Epilepsy Center Division, NYU School of Medicine, New York, NY 10016, USA
    J Neuroinflammation 10:142. 2013
  3. doi request reprint Extralimbic autoimmune encephalitis associated with glutamic acid decarboxylase antibodies: an underdiagnosed entity?
    Souhel Najjar
    NYU Comprehensive Epilepsy Center, New York University School of Medicine, New York, NY 10016, USA
    Epilepsy Behav 21:306-13. 2011
  4. doi request reprint Refractory epilepsy associated with microglial activation
    Souhel Najjar
    Department of Neurology, NYU Comprehensive Epilepsy Center, USA
    Neurologist 17:249-54. 2011
  5. doi request reprint Glutamic acid decarboxylase autoantibody syndrome presenting as schizophrenia
    Souhel Najjar
    Department of Neurology, New York University School of Medicine, New York, NY, USA
    Neurologist 18:88-91. 2012
  6. doi request reprint Neuropsychiatric autoimmune encephalitis without VGKC-complex, NMDAR, and GAD autoantibodies: case report and literature review
    Souhel Najjar
    New York University Comprehensive Epilepsy Center, New York, NY 10016, USA
    Cogn Behav Neurol 26:36-49. 2013
  7. pmc Neuroinflammation and psychiatric illness
    Souhel Najjar
    Department of Neurology, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA
    J Neuroinflammation 10:43. 2013
  8. doi request reprint Spontaneously resolving seronegative autoimmune limbic encephalitis
    Souhel Najjar
    Departments of Neurology, Pathology Division of Neuropathology, Neurosurgery and Psychiatry, NYU Comprehensive Epilepsy Center, New York University School of Medicine, New York, NY, USA
    Cogn Behav Neurol 24:99-105. 2011
  9. doi request reprint Glia and epilepsy: excitability and inflammation
    Orrin Devinsky
    Epilepsy Center, Department of Neurology, NYU School of Medicine, New York, NY 10016, USA
    Trends Neurosci 36:174-84. 2013
  10. ncbi request reprint Immunology and epilepsy
    Souhel Najjar
    Comprehensive Epilepsy Center, Department of Neurology, NYU School of Medicine, New York, NY, USA
    Rev Neurol Dis 5:109-16. 2008

Collaborators

Detail Information

Publications14

  1. doi request reprint Neuroinflammation and white matter pathology in schizophrenia: systematic review
    Souhel Najjar
    Neuroinflammation Research Group, Epilepsy Center Division, Department of Neurology, NYU School of Medicine, New York, New York, United States Electronic address
    Schizophr Res 161:102-12. 2015
    ....
  2. pmc Neurovascular unit dysfunction with blood-brain barrier hyperpermeability contributes to major depressive disorder: a review of clinical and experimental evidence
    Souhel Najjar
    Department of Neurology, Neuroinflammation Research Group, Epilepsy Center Division, NYU School of Medicine, New York, NY 10016, USA
    J Neuroinflammation 10:142. 2013
    ..Understanding the contribution of neurovascular dysfunction with BBB hyperpermeability to the pathophysiology of MDD may help to identify novel therapeutic and preventative approaches...
  3. doi request reprint Extralimbic autoimmune encephalitis associated with glutamic acid decarboxylase antibodies: an underdiagnosed entity?
    Souhel Najjar
    NYU Comprehensive Epilepsy Center, New York University School of Medicine, New York, NY 10016, USA
    Epilepsy Behav 21:306-13. 2011
    ....
  4. doi request reprint Refractory epilepsy associated with microglial activation
    Souhel Najjar
    Department of Neurology, NYU Comprehensive Epilepsy Center, USA
    Neurologist 17:249-54. 2011
    ..Experimental and clinical studies support a pathogenic role of microglial activation and proliferation (MAP) in epileptogenesis...
  5. doi request reprint Glutamic acid decarboxylase autoantibody syndrome presenting as schizophrenia
    Souhel Najjar
    Department of Neurology, New York University School of Medicine, New York, NY, USA
    Neurologist 18:88-91. 2012
    ..Anti-GAD antibodies (GADAbs) can cause several neurological disorders. However, the association between anti-GADAbs and pure psychosis, without seizures or focal neurological deficits, is not well defined...
  6. doi request reprint Neuropsychiatric autoimmune encephalitis without VGKC-complex, NMDAR, and GAD autoantibodies: case report and literature review
    Souhel Najjar
    New York University Comprehensive Epilepsy Center, New York, NY 10016, USA
    Cogn Behav Neurol 26:36-49. 2013
    ..We propose a standardized classification system for the autoimmune encephalitides, integrating earlier pathology-oriented terms with more recently defined serologic and clinical phenotypes...
  7. pmc Neuroinflammation and psychiatric illness
    Souhel Najjar
    Department of Neurology, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA
    J Neuroinflammation 10:43. 2013
    ..Understanding how psychosocial, genetic, immunological and neurotransmitter systems interact can reveal pathogenic clues and help target new preventive and symptomatic therapies...
  8. doi request reprint Spontaneously resolving seronegative autoimmune limbic encephalitis
    Souhel Najjar
    Departments of Neurology, Pathology Division of Neuropathology, Neurosurgery and Psychiatry, NYU Comprehensive Epilepsy Center, New York University School of Medicine, New York, NY, USA
    Cogn Behav Neurol 24:99-105. 2011
    ..We describe a patient with seronegative autoimmune limbic encephalitis (SNALE) masquerading as glioma. Brain magnetic resonance imaging (MRI) abnormalities, distinctive pathological findings, and spontaneous remission are highlighted...
  9. doi request reprint Glia and epilepsy: excitability and inflammation
    Orrin Devinsky
    Epilepsy Center, Department of Neurology, NYU School of Medicine, New York, NY 10016, USA
    Trends Neurosci 36:174-84. 2013
    ..This review critically evaluates the role of glia-induced hyperexcitability and inflammation in epilepsy...
  10. ncbi request reprint Immunology and epilepsy
    Souhel Najjar
    Comprehensive Epilepsy Center, Department of Neurology, NYU School of Medicine, New York, NY, USA
    Rev Neurol Dis 5:109-16. 2008
    ..The prevalence and impact of immunopathology in epilepsy syndromes remains to be determined by future research...
  11. doi request reprint Meta-analysis of the association between N-methyl-d-aspartate receptor antibodies and schizophrenia, schizoaffective disorder, bipolar disorder, and major depressive disorder
    Daniel M Pearlman
    Neuroinflammation Research Group, Epilepsy Center Division, Department of Neurology, NYU School of Medicine, New York, NY, USA The Dartmouth Institute for Health Policy and Clinical Practice, Audrey and Theodor Geisel School of Medicine at Dartmouth, Lebanon, NH, USA
    Schizophr Res 157:249-58. 2014
    ....
  12. doi request reprint Anti-basal ganglia antibodies in primary obsessive-compulsive disorder: systematic review and meta-analysis
    Daniel M Pearlman
    Daniel M Pearlman, MPH, The Dartmouth Institute for Health Policy and Clinical Practice, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire, and Neuroinflammation Research Group, Epilepsy Center Division, Department of Neurology, NYU School of Medicine, New York Haily S Vora, MPH, Brian G Marquis, MS, The Dartmouth Institute for Health Policy and Clinical Practice, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire Souhel Najjar, MD, Neuroinflammation Research Group, Epilepsy Center Division, Department of Neurology, NYU School of Medicine, New York Lauren A Dudley, MD, The Dartmouth Institute for Health Policy and Clinical Practice, Geisel School of Medicine at Dartmouth, and Section of Rheumatology, Department of Medicine, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire, USA
    Br J Psychiatry 205:8-16. 2014
    ..g. Sydenham chorea). The relationship between autoimmunity and primary obsessive-compulsive disorder (OCD), however, is less clear...
  13. doi request reprint Blood levels of S-100 calcium-binding protein B, high-sensitivity C-reactive protein, and interleukin-6 for changes in depressive symptom severity after coronary artery bypass grafting: prospective cohort nested within a randomized, controlled trial
    Daniel M Pearlman
    Neuroinflammation Research Group, Epilepsy Center Division, Department of Neurology, NYU School of Medicine, New York, New York, United States of America The Dartmouth Institute for Health Policy and Clinical Practice, Audrey and Theodor Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, United States of America
    PLoS ONE 9:e111110. 2014
    ....
  14. pmc Epilepsy associated with systemic autoimmune disorders
    Orrin Devinsky
    Department of Neurology, NYU Langone School of Medicine, New York, NY
    Epilepsy Curr 13:62-8. 2013
    ..In some cases, they are clues to metabolic or infectious disorders or medication toxicity; in other cases, seizures herald a life-threatening progression of the underlying illness...