Richard M Myers

Summary

Publications

  1. pmc Functional analysis of transcription factor binding sites in human promoters
    Troy W Whitfield
    Program in Bioinformatics and Integrative Biology and Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01605, USA
    Genome Biol 13:R50. 2012
  2. pmc Characterization of X-linked SNP genotypic variation in globally distributed human populations
    Amanda M Casto
    Department of Genetics, Stanford University, Mail Stop 5120, Stanford, California 94305, USA
    Genome Biol 11:R10. 2010
  3. pmc Characterizing the admixed African ancestry of African Americans
    Fouad Zakharia
    Department of Genetics, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305, USA
    Genome Biol 10:R141. 2009
  4. pmc Distinct properties of cell-type-specific and shared transcription factor binding sites
    Jason Gertz
    HudsonAlpha Institute for Biotechnology, 601 Genome Way, Huntsville, AL 35806, USA
    Mol Cell 52:25-36. 2013
  5. pmc Dynamic DNA methylation across diverse human cell lines and tissues
    Katherine E Varley
    HudsonAlpha Institute for Biotechnology, Huntsville, AL 35806, USA
    Genome Res 23:555-67. 2013
  6. pmc Genistein and bisphenol A exposure cause estrogen receptor 1 to bind thousands of sites in a cell type-specific manner
    Jason Gertz
    HudsonAlpha Institute for Biotechnology, Huntsville, AL 35806, USA
    Genome Res 22:2153-62. 2012
  7. pmc The hypersensitive glucocorticoid response specifically regulates period 1 and expression of circadian genes
    Timothy E Reddy
    HudsonAlpha Institute for Biotechnology, Huntsville, Alabama, USA
    Mol Cell Biol 32:3756-67. 2012
  8. pmc Effects of sequence variation on differential allelic transcription factor occupancy and gene expression
    Timothy E Reddy
    HudsonAlpha Institute for Biotechnology, Huntsville, AL 35806, USA
    Genome Res 22:860-9. 2012

Detail Information

Publications9

  1. pmc Functional analysis of transcription factor binding sites in human promoters
    Troy W Whitfield
    Program in Bioinformatics and Integrative Biology and Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01605, USA
    Genome Biol 13:R50. 2012
    ..We carried out functional tests on these sites in four different immortalized human cell lines using transient transfections with a luciferase reporter assay, primarily for the transcription factors CTCF, GABP, GATA2, E2F, STAT, and YY1...
  2. pmc Characterization of X-linked SNP genotypic variation in globally distributed human populations
    Amanda M Casto
    Department of Genetics, Stanford University, Mail Stop 5120, Stanford, California 94305, USA
    Genome Biol 11:R10. 2010
    ..Here we characterize the genomic variation represented by 16,297 X-linked SNPs genotyped in the CEPH human genome diversity project samples...
  3. pmc Characterizing the admixed African ancestry of African Americans
    Fouad Zakharia
    Department of Genetics, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305, USA
    Genome Biol 10:R141. 2009
    ..To focus on African ancestry, we reduced the data to include only those genotypes in each African American determined statistically to be African in origin...
  4. pmc Distinct properties of cell-type-specific and shared transcription factor binding sites
    Jason Gertz
    HudsonAlpha Institute for Biotechnology, 601 Genome Way, Huntsville, AL 35806, USA
    Mol Cell 52:25-36. 2013
    ..The distinct properties of cell-specific binding were also observed with glucocorticoid receptor and for ER in primary mouse tissues, representing an elegant genomic encoding scheme for generating cell-type-specific gene regulation. ..
  5. pmc Dynamic DNA methylation across diverse human cell lines and tissues
    Katherine E Varley
    HudsonAlpha Institute for Biotechnology, Huntsville, AL 35806, USA
    Genome Res 23:555-67. 2013
    ..This study provides an atlas of DNA methylation across diverse and well-characterized samples and enables new discoveries about DNA methylation and its role in gene regulation and disease...
  6. pmc Genistein and bisphenol A exposure cause estrogen receptor 1 to bind thousands of sites in a cell type-specific manner
    Jason Gertz
    HudsonAlpha Institute for Biotechnology, Huntsville, AL 35806, USA
    Genome Res 22:2153-62. 2012
    ....
  7. pmc The hypersensitive glucocorticoid response specifically regulates period 1 and expression of circadian genes
    Timothy E Reddy
    HudsonAlpha Institute for Biotechnology, Huntsville, Alabama, USA
    Mol Cell Biol 32:3756-67. 2012
    ..These findings show that hypersensitive GR binding occurs throughout the genome, drives targeted gene expression, and may be important to endocrine mediation of peripheral circadian rhythms...
  8. pmc Effects of sequence variation on differential allelic transcription factor occupancy and gene expression
    Timothy E Reddy
    HudsonAlpha Institute for Biotechnology, Huntsville, AL 35806, USA
    Genome Res 22:860-9. 2012
    ..Our results have the potential to increase the power and interpretability of association studies by targeting functional intergenic variants in addition to protein coding sequences...