R N Muller

Summary

Publications

  1. ncbi Development of a magnetic resonance imaging protocol for the characterization of atherosclerotic plaque by using vascular cell adhesion molecule-1 and apoptosis-targeted ultrasmall superparamagnetic iron oxide derivatives
    Carmen Burtea
    Department of General, Organic and Biomedical Chemistry, NMR and Molecular Imaging Laboratory, University of Mons, Avenue Maistriau 19, Mendeleev Building, B 7000 Mons, Belgium
    Arterioscler Thromb Vasc Biol 32:e36-48. 2012
  2. ncbi Iron oxide based MR contrast agents: from chemistry to cell labeling
    S Laurent
    Department of General, Organic and Biomedical Chemistry, NMR and Molecular Imaging Laboratory, University of Mons, B 7000 Mons, Belgium
    Curr Med Chem 16:4712-27. 2009
  3. ncbi In vitro characterization of the Gd complex of [2,6-pyridinediylbis(methylene nitrilo)] tetraacetic acid (PMN-tetraacetic acid) and of its Eu analogue, suitable bimodal contrast agents for MRI and optical imaging
    S Laurent
    NMR and Molecular Imaging Laboratory, Department of General, Organic and Biomedical Chemistry, University of Mons Hainaut, B 7000 Mons, Belgium
    Bioorg Med Chem Lett 17:6230-3. 2007
  4. ncbi Lanthanide complexes for magnetic resonance and optical molecular imaging
    S Laurent
    Department of General Organic and Biomedical Chemistry Laboratory of NMR and Molecular Imaging, University of Mons, Mons, Belgium
    Q J Nucl Med Mol Imaging 53:586-603. 2009
  5. ncbi Synthesis and physicochemical characterization of Gd-C4-thyroxin-DTPA, a potential MRI contrast agent. Evaluation of its affinity for human serum albumin by proton relaxometry, NMR diffusometry, and electrospray mass spectrometry
    C Henoumont
    Department of General, Organic and Biomedical Chemistry, NMR and Molecular Imaging Laboratory, University of Mons, 19 Avenue Maistriau, B 7000 Mons, Belgium
    J Phys Chem B 114:3689-97. 2010
  6. ncbi Magnetic iron oxide nanoparticles for biomedical applications
    Sophie Laurent
    Department of General, Organic and Biomedical Chemistry, University of Mons, B 7000 Mons, Belgium
    Future Med Chem 2:427-49. 2010

Collaborators

  • S Laurent
  • Carmen Burtea
  • C Henoumont
  • Walter Gonzalez
  • Marc Port
  • Olivier Rousseaux
  • Sébastien Ballet
  • Luce Vander Elst
  • Claire Corot
  • Anne Dencausse
  • L Vander Elst

Detail Information

Publications6

  1. ncbi Development of a magnetic resonance imaging protocol for the characterization of atherosclerotic plaque by using vascular cell adhesion molecule-1 and apoptosis-targeted ultrasmall superparamagnetic iron oxide derivatives
    Carmen Burtea
    Department of General, Organic and Biomedical Chemistry, NMR and Molecular Imaging Laboratory, University of Mons, Avenue Maistriau 19, Mendeleev Building, B 7000 Mons, Belgium
    Arterioscler Thromb Vasc Biol 32:e36-48. 2012
    ....
  2. ncbi Iron oxide based MR contrast agents: from chemistry to cell labeling
    S Laurent
    Department of General, Organic and Biomedical Chemistry, NMR and Molecular Imaging Laboratory, University of Mons, B 7000 Mons, Belgium
    Curr Med Chem 16:4712-27. 2009
    ..Thus, experimentally as well as in a few trials on humans, iron oxide particles currently find promising applications...
  3. ncbi In vitro characterization of the Gd complex of [2,6-pyridinediylbis(methylene nitrilo)] tetraacetic acid (PMN-tetraacetic acid) and of its Eu analogue, suitable bimodal contrast agents for MRI and optical imaging
    S Laurent
    NMR and Molecular Imaging Laboratory, Department of General, Organic and Biomedical Chemistry, University of Mons Hainaut, B 7000 Mons, Belgium
    Bioorg Med Chem Lett 17:6230-3. 2007
    ..Both complexes have a good stability in physiological medium...
  4. ncbi Lanthanide complexes for magnetic resonance and optical molecular imaging
    S Laurent
    Department of General Organic and Biomedical Chemistry Laboratory of NMR and Molecular Imaging, University of Mons, Mons, Belgium
    Q J Nucl Med Mol Imaging 53:586-603. 2009
    ..The luminescence properties show high quantum yield and long luminescence lifetimes. The relaxometric data of the Gd complexes are comparable or higher than commercial and clinically Gd-DTPA derivatives...
  5. ncbi Synthesis and physicochemical characterization of Gd-C4-thyroxin-DTPA, a potential MRI contrast agent. Evaluation of its affinity for human serum albumin by proton relaxometry, NMR diffusometry, and electrospray mass spectrometry
    C Henoumont
    Department of General, Organic and Biomedical Chemistry, NMR and Molecular Imaging Laboratory, University of Mons, 19 Avenue Maistriau, B 7000 Mons, Belgium
    J Phys Chem B 114:3689-97. 2010
    ..The kinetics of the exchange between the bound and the free form of the complex was evaluated by the NMR diffusometry technique. Competition experiments have allowed the assignment of the chelate's binding site on HSA...
  6. ncbi Magnetic iron oxide nanoparticles for biomedical applications
    Sophie Laurent
    Department of General, Organic and Biomedical Chemistry, University of Mons, B 7000 Mons, Belgium
    Future Med Chem 2:427-49. 2010
    ..Nanoparticles can be used for numerous in vivo applications, such as MRI contrast enhancement and hyperthermia drug delivery. New developments focus on targeting through molecular imaging and cell tracking...