Hugh E Mulcahy

Summary

Publications

  1. ncbi request reprint From dinosaurs to DNA: a history of colorectal cancer
    Hugh E Mulcahy
    Centre for Colorectal Diseases, St Vincent s University Hospital, Elm Park, Dublin 4, Ireland
    Int J Colorectal Dis 18:210-5. 2003
  2. ncbi request reprint Changing patterns of sedation use for routine out-patient diagnostic gastroscopy between 1989 and 1998
    H E Mulcahy
    Digestive Diseases Research Centre, St Bartholomew s and Royal London School of Medicine and Dentistry, London, UK
    Aliment Pharmacol Ther 15:217-20. 2001
  3. ncbi request reprint A prospective controlled trial of an ultrathin versus a conventional endoscope in unsedated upper gastrointestinal endoscopy
    H E Mulcahy
    Digestive Diseases Research Centre, St Bartholomew s and the Royal London School of Medicine and Dentistry, London, UK
    Endoscopy 33:311-6. 2001
  4. ncbi request reprint Factors associated with tolerance to, and discomfort with, unsedated diagnostic gastroscopy
    H E Mulcahy
    Dept of Gastroenterology, Homerton Hospital, London, UK
    Scand J Gastroenterol 36:1352-7. 2001
  5. doi request reprint The Short Health Scale: a valid and reliable measure of health related quality of life in English speaking inflammatory bowel disease patients
    Edel McDermott
    Centre for Colorectal Disease, St Vincent s University Hospital University College Dublin, Elm Park, Dublin 4, Ireland
    J Crohns Colitis 7:616-21. 2013
  6. pmc Tumour tissue microenvironment can inhibit dendritic cell maturation in colorectal cancer
    Adriana J Michielsen
    Centre for Colorectal Disease, St Vincent s University Hospital, Elm Park, Dublin, Ireland
    PLoS ONE 6:e27944. 2011
  7. doi request reprint Surgery, Crohn's disease, and the biological era: has there been an impact?
    Eoin Slattery
    Centre for Colorectal Disease, St Vincent s University Hospital, Dublin, Ireland
    J Clin Gastroenterol 45:691-3. 2011
  8. doi request reprint Increased topoisomerase IIalpha expression in colorectal cancer is associated with advanced disease and chemotherapeutic resistance via inhibition of apoptosis
    Alan Coss
    Centre for Colorectal Disease, St Vincent s University Hospital, Dublin, Ireland
    Cancer Lett 276:228-38. 2009
  9. doi request reprint A comparative study of short- and medium-term outcomes comparing emergent surgery and stenting as a bridge to surgery in patients with acute malignant colonic obstruction
    Dara O Kavanagh
    Center for Colorectal Disease, St Vincent University Hospital, Elm Park, and School of Medicine and Medical Sciences, University College Dublin, Dublin, Ireland
    Dis Colon Rectum 56:433-40. 2013
  10. doi request reprint Impact of magnetic resonance enterography in the management of small bowel Crohn's disease
    Danny G Cheriyan
    Department of Gastroenterology Hospital, St Vincent s University Hospital, Centre for Colorectal Disease, Dublin, Ireland
    Eur J Gastroenterol Hepatol 25:550-5. 2013

Collaborators

Detail Information

Publications14

  1. ncbi request reprint From dinosaurs to DNA: a history of colorectal cancer
    Hugh E Mulcahy
    Centre for Colorectal Diseases, St Vincent s University Hospital, Elm Park, Dublin 4, Ireland
    Int J Colorectal Dis 18:210-5. 2003
    ....
  2. ncbi request reprint Changing patterns of sedation use for routine out-patient diagnostic gastroscopy between 1989 and 1998
    H E Mulcahy
    Digestive Diseases Research Centre, St Bartholomew s and Royal London School of Medicine and Dentistry, London, UK
    Aliment Pharmacol Ther 15:217-20. 2001
    ..However, no data are available on sedation trends in Britain over the past 10 years...
  3. ncbi request reprint A prospective controlled trial of an ultrathin versus a conventional endoscope in unsedated upper gastrointestinal endoscopy
    H E Mulcahy
    Digestive Diseases Research Centre, St Bartholomew s and the Royal London School of Medicine and Dentistry, London, UK
    Endoscopy 33:311-6. 2001
    ..We assessed the effect of endoscope diameter on patient discomfort during unsedated transoral gastroscopy...
  4. ncbi request reprint Factors associated with tolerance to, and discomfort with, unsedated diagnostic gastroscopy
    H E Mulcahy
    Dept of Gastroenterology, Homerton Hospital, London, UK
    Scand J Gastroenterol 36:1352-7. 2001
    ..We prospectively assessed patient and endoscopic variables in subjects attending for endoscopy in order to identify factors associated with patients' experience of the unsedated examination...
  5. doi request reprint The Short Health Scale: a valid and reliable measure of health related quality of life in English speaking inflammatory bowel disease patients
    Edel McDermott
    Centre for Colorectal Disease, St Vincent s University Hospital University College Dublin, Elm Park, Dublin 4, Ireland
    J Crohns Colitis 7:616-21. 2013
    ..The four dimensions include bowel symptoms, activities of daily life, worry and general wellbeing. It has previously been validated in Swedish and Norwegian speaking patients...
  6. pmc Tumour tissue microenvironment can inhibit dendritic cell maturation in colorectal cancer
    Adriana J Michielsen
    Centre for Colorectal Disease, St Vincent s University Hospital, Elm Park, Dublin, Ireland
    PLoS ONE 6:e27944. 2011
    ..In conclusion, tumour conditioned media strongly influences dendritic cell maturation and function...
  7. doi request reprint Surgery, Crohn's disease, and the biological era: has there been an impact?
    Eoin Slattery
    Centre for Colorectal Disease, St Vincent s University Hospital, Dublin, Ireland
    J Clin Gastroenterol 45:691-3. 2011
    ..The management of Crohn's disease (CD) has changed considerably over the last 20 years. Immunomodulators and biological therapies now play a role in treating patients with CD, but little is known of their influence on surgical rates...
  8. doi request reprint Increased topoisomerase IIalpha expression in colorectal cancer is associated with advanced disease and chemotherapeutic resistance via inhibition of apoptosis
    Alan Coss
    Centre for Colorectal Disease, St Vincent s University Hospital, Dublin, Ireland
    Cancer Lett 276:228-38. 2009
    ..Our results suggest that gene amplification may represent an important mechanism underlying these changes...
  9. doi request reprint A comparative study of short- and medium-term outcomes comparing emergent surgery and stenting as a bridge to surgery in patients with acute malignant colonic obstruction
    Dara O Kavanagh
    Center for Colorectal Disease, St Vincent University Hospital, Elm Park, and School of Medicine and Medical Sciences, University College Dublin, Dublin, Ireland
    Dis Colon Rectum 56:433-40. 2013
    ..However, concerns about the safety of stenting have been raised following recent randomized studies...
  10. doi request reprint Impact of magnetic resonance enterography in the management of small bowel Crohn's disease
    Danny G Cheriyan
    Department of Gastroenterology Hospital, St Vincent s University Hospital, Centre for Colorectal Disease, Dublin, Ireland
    Eur J Gastroenterol Hepatol 25:550-5. 2013
    ..Magnetic resonance enterography (MRE) is a relatively new imaging modality that involves small bowel distension with orally administered fluid. Few studies have assessed its impact on patient management...
  11. doi request reprint Stage II colonic adenocarcinoma: a detailed study of pT4N0 with emphasis on peritoneal involvement and the role of tumour budding
    Aoife L Canney
    Centre for Colorectal Disease, St Vincent s University Hospital, Dublin, Ireland
    Histopathology 61:488-96. 2012
    ..Evaluation of peritoneal involvement in colonic cancer (CC) can be difficult. We studied pT4N0 cancers and their association with pathological prognostic markers, including tumour budding...
  12. doi request reprint Development, validation and clinical assessment of a short questionnaire to assess disease-related knowledge in inflammatory bowel disease patients
    Denise Keegan
    Department of Gastroenterology, Centre for Colorectal Disease, St Vincent s University Hospital University College Dublin, Elm Park, Dublin, Ireland
    Scand J Gastroenterol 48:183-8. 2013
    ..The aim of this study was to develop and validate a short knowledge questionnaire for clinical and academic research purposes...
  13. doi request reprint A 5-year prospective observational study of the outcomes of international treatment guidelines for Crohn's disease
    Garret Cullen
    Centre for Colorectal Disease, St Vincent s University Hospital, Dublin, Ireland
    Clin Gastroenterol Hepatol 7:323-8; quiz 252. 2009
    ..We reviewed outcomes and corticosteroid-dependency rates of patients with moderate-to-severe disease who were treated according to the international guidelines...
  14. pmc Mutually exclusive promoter hypermethylation patterns of hMLH1 and O6-methylguanine DNA methyltransferase in colorectal cancer
    Edward J Fox
    Department of Pathology, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin 4, Ireland
    J Mol Diagn 8:68-75. 2006
    ..01). We demonstrated an inverse relationship between hMLH1 promoter hypermethylation and MGMT promoter hypermethylation (P = 0.041), suggesting that a number of distinct hypermethylation-associated pathways may exist in colorectal cancer...