J Mukherjee

Summary

Publications

  1. ncbi request reprint Preliminary assessment of extrastriatal dopamine D-2 receptor binding in the rodent and nonhuman primate brains using the high affinity radioligand, 18F-fallypride
    J Mukherjee
    Department of Radiology, Franklin McLean Institute, University of Chicago, Illinois, USA
    Nucl Med Biol 26:519-27. 1999
  2. ncbi request reprint 18F-desmethoxyfallypride: a fluorine-18 labeled radiotracer with properties similar to carbon-11 raclopride for PET imaging studies of dopamine D2 receptors
    J Mukherjee
    Franklin McLean Institute, Department of Radiology, University of Chicago, IL 60637, USA
    Life Sci 59:669-78. 1996
  3. ncbi request reprint Development of N-[3-(2',4'-dichlorophenoxy)-2-18F-fluoropropyl]-N-methylpropargylamine (18F-fluoroclorgyline) as a potential PET radiotracer for monoamine oxidase-A
    J Mukherjee
    Franklin McLean Institute, Department of Radiology, University of Chicago, Illinois, USA
    Nucl Med Biol 26:619-25. 1999
  4. ncbi request reprint Evaluation of d-amphetamine effects on the binding of dopamine D-2 receptor radioligand, 18F-fallypride in nonhuman primates using positron emission tomography
    J Mukherjee
    Franklin McLean Institute, Department of Radiology, University of Chicago, Illinois 60637, USA
    Synapse 27:1-13. 1997
  5. ncbi request reprint Evaluation of monoamine oxidase B inhibition by fluoxetine (Prozac): an in vitro and in vivo study
    J Mukherjee
    Department of Radiology, Franklin McLean Institute, The University of Chicago, IL 60637, USA
    Eur J Pharmacol 337:111-4. 1997
  6. ncbi request reprint Evaluation of the binding of the radiolabeled antidepressant drug, 18F-fluoxetine in the rodent brain: an in vitro and in vivo study
    J Mukherjee
    Department of Radiology, Franklin McLean Institute, University of Chicago, IL 60637, USA
    Nucl Med Biol 25:605-10. 1998
  7. ncbi request reprint Fluorinated benzamide neuroleptics--2. Synthesis and radiosynthesis of (S)-N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-(3-[18F]fluoropropyl)-3- substituted-2-methoxybenzamides
    J Mukherjee
    Department of Radiology, University of Chicago, IL 60637
    Int J Rad Appl Instrum A 42:713-21. 1991
  8. ncbi request reprint Monoamine oxidase A inhibition by fluoxetine: an in vitro and in vivo study
    J Mukherjee
    Franklin McLean Institute, Department of Radiology, The University of Chicago, Illinois 60637, USA
    Synapse 31:285-9. 1999

Detail Information

Publications8

  1. ncbi request reprint Preliminary assessment of extrastriatal dopamine D-2 receptor binding in the rodent and nonhuman primate brains using the high affinity radioligand, 18F-fallypride
    J Mukherjee
    Department of Radiology, Franklin McLean Institute, University of Chicago, Illinois, USA
    Nucl Med Biol 26:519-27. 1999
    ..Postmortem analysis of the monkey brain revealed significant 18F-fallypride binding in the striata, whereas binding was also observed in extrastriatal regions such as the thalamus, cortical areas, and brain stem...
  2. ncbi request reprint 18F-desmethoxyfallypride: a fluorine-18 labeled radiotracer with properties similar to carbon-11 raclopride for PET imaging studies of dopamine D2 receptors
    J Mukherjee
    Franklin McLean Institute, Department of Radiology, University of Chicago, IL 60637, USA
    Life Sci 59:669-78. 1996
    ..The sensitivity of 18F-desmethoxyfallypride towards competition with dopamine should make this radiotracer useful in PET studies to evaluate in vivo pharmacological effects of various agents that alter levels of endogenous dopamine...
  3. ncbi request reprint Development of N-[3-(2',4'-dichlorophenoxy)-2-18F-fluoropropyl]-N-methylpropargylamine (18F-fluoroclorgyline) as a potential PET radiotracer for monoamine oxidase-A
    J Mukherjee
    Franklin McLean Institute, Department of Radiology, University of Chicago, Illinois, USA
    Nucl Med Biol 26:619-25. 1999
    ..These results suggest that 18F-fluoroclorgyline is a potential PET radiotracer for MAO-A...
  4. ncbi request reprint Evaluation of d-amphetamine effects on the binding of dopamine D-2 receptor radioligand, 18F-fallypride in nonhuman primates using positron emission tomography
    J Mukherjee
    Franklin McLean Institute, Department of Radiology, University of Chicago, Illinois 60637, USA
    Synapse 27:1-13. 1997
    ..75-1.50 mg/kg, with an approximately 16%/hour reduction in binding. These results indicate that AMPH stimulated release of endogenous dopamine reduces the specific binding of 18F-fallypride...
  5. ncbi request reprint Evaluation of monoamine oxidase B inhibition by fluoxetine (Prozac): an in vitro and in vivo study
    J Mukherjee
    Department of Radiology, Franklin McLean Institute, The University of Chicago, IL 60637, USA
    Eur J Pharmacol 337:111-4. 1997
    ..989). These results provide evidence for a potential role of monoamine oxidase B inhibition in the therapeutic effects of Prozac...
  6. ncbi request reprint Evaluation of the binding of the radiolabeled antidepressant drug, 18F-fluoxetine in the rodent brain: an in vitro and in vivo study
    J Mukherjee
    Department of Radiology, Franklin McLean Institute, University of Chicago, IL 60637, USA
    Nucl Med Biol 25:605-10. 1998
    ..Other sites, such as monoamine oxidase, may also play a significant role in the action of fluoxetine...
  7. ncbi request reprint Fluorinated benzamide neuroleptics--2. Synthesis and radiosynthesis of (S)-N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-(3-[18F]fluoropropyl)-3- substituted-2-methoxybenzamides
    J Mukherjee
    Department of Radiology, University of Chicago, IL 60637
    Int J Rad Appl Instrum A 42:713-21. 1991
    ..Total synthesis and purification time required for either [18F]FPHB or [18F]FPMB was 120 min from EOB...
  8. ncbi request reprint Monoamine oxidase A inhibition by fluoxetine: an in vitro and in vivo study
    J Mukherjee
    Franklin McLean Institute, Department of Radiology, The University of Chicago, Illinois 60637, USA
    Synapse 31:285-9. 1999
    ..These results provide evidence on the in vitro and in vivo inhibition of monoamine oxidase A by fluoxetine...