Iordanis Mourouzis

Summary

Publications

  1. doi request reprint Masked hypertension and atherogenesis: the impact of apelin and relaxin plasma levels
    Dimitris P Papadopoulos
    ESH Excellent Center of Hypertension, Laiko University Hospital, Athens, Greece
    J Clin Hypertens (Greenwich) 15:333-6. 2013
  2. doi request reprint Hemostasis parameters disturbances in healthy individuals with prehypertension
    Dimitris Papadopoulos
    ESH Excellent Center of Hypertension, Laiko University Hospital, Athens, Greece
    Clin Exp Hypertens 34:385-8. 2012
  3. ncbi request reprint Bilateral fistulas: a rare cause of chest pain. Case report with literature review
    Dimitris P Papadopoulos
    Department of Cardiology, Laiko Hospital, Athens Medical School, Athens, Greece
    Hellenic J Cardiol 49:111-3. 2008
  4. doi request reprint Hypertrophic and hypertensive hypertrophic cardiomyopathy--a true association?
    Dimitris P Papadopoulos
    Hypertension Clinic, Department of Cardiology, Laiko University Hospital, Athens, Greece
    Angiology 61:92-9. 2010
  5. ncbi request reprint Antiendothelial cell antibody levels in healthy normotensives with high normal blood pressure
    D P Papadopoulos
    Department of Cardiology, Laiko Hospital, Athens, Greece
    Clin Exp Hypertens 28:663-7. 2006
  6. ncbi request reprint Human soluble leptin receptor concentration in healthy offspring of hypertensive parents
    Dimitris P Papadopoulos
    Department of Cardiology, Laiko Hospital, Athens, Greece
    J Clin Hypertens (Greenwich) 8:797-802. 2006
  7. ncbi request reprint White coat hypertension and haemostatic/fibrinolytic balance disorders
    Thomas Makris
    Department of Cardiology, Laiko General Hospital, 6 8 Glyconos street, 106 75 Athens, Greece
    Eur Cytokine Netw 17:137-41. 2006
  8. ncbi request reprint Stent treatment of an aortocoronary dissection during percutaneous coronary intervention. A case report and brief literature review
    Dimitris P Papadopoulos
    Dept of Cardiology, Laiko Hospital of Athens, Greece
    Acta Cardiol 61:119-21. 2006
  9. ncbi request reprint Adiponectin and resistin plasma levels in healthy individuals with prehypertension
    Dimitrios P Papadopoulos
    Department of Cardiology, Laiko Hospital, Athens, Greece
    J Clin Hypertens (Greenwich) 7:729-33. 2005
  10. doi request reprint Depression masked as paroxysmal hypertension episodes
    Dimitris P Papadopoulos
    Hypertension Clinic, Laiko University Hospital, 24 Agiou Ioannou Theologou Street, 15561 Athens, Greece
    Blood Press 19:16-9. 2010

Collaborators

Detail Information

Publications82

  1. doi request reprint Masked hypertension and atherogenesis: the impact of apelin and relaxin plasma levels
    Dimitris P Papadopoulos
    ESH Excellent Center of Hypertension, Laiko University Hospital, Athens, Greece
    J Clin Hypertens (Greenwich) 15:333-6. 2013
    ..This observation may have prognostic significance for future cardiovascular events in patients with MH and needs further investigation...
  2. doi request reprint Hemostasis parameters disturbances in healthy individuals with prehypertension
    Dimitris Papadopoulos
    ESH Excellent Center of Hypertension, Laiko University Hospital, Athens, Greece
    Clin Exp Hypertens 34:385-8. 2012
    ..This observation may be of prognostic value for future cardiovascular events in this group and needs further investigation...
  3. ncbi request reprint Bilateral fistulas: a rare cause of chest pain. Case report with literature review
    Dimitris P Papadopoulos
    Department of Cardiology, Laiko Hospital, Athens Medical School, Athens, Greece
    Hellenic J Cardiol 49:111-3. 2008
    ..There was no evidence of atherosclerotic coronary artery disease in either the left or right coronary arterial tree...
  4. doi request reprint Hypertrophic and hypertensive hypertrophic cardiomyopathy--a true association?
    Dimitris P Papadopoulos
    Hypertension Clinic, Department of Cardiology, Laiko University Hospital, Athens, Greece
    Angiology 61:92-9. 2010
    ..The aim of this review was to highlighted this syndrome from pathophysiological, clinical, diagnostical view and clear all the possible correlations with genetic, inflammatory, and other markers...
  5. ncbi request reprint Antiendothelial cell antibody levels in healthy normotensives with high normal blood pressure
    D P Papadopoulos
    Department of Cardiology, Laiko Hospital, Athens, Greece
    Clin Exp Hypertens 28:663-7. 2006
    ..The aim of this study was to compare AECA levels of healthy normotensives with HNBP to those of healthy normotensives with normal blood pressure (NBP), matched for age, sex, and body mass index (BMI)...
  6. ncbi request reprint Human soluble leptin receptor concentration in healthy offspring of hypertensive parents
    Dimitris P Papadopoulos
    Department of Cardiology, Laiko Hospital, Athens, Greece
    J Clin Hypertens (Greenwich) 8:797-802. 2006
    ..Further studies are needed to determine the clinical significance of these observations...
  7. ncbi request reprint White coat hypertension and haemostatic/fibrinolytic balance disorders
    Thomas Makris
    Department of Cardiology, Laiko General Hospital, 6 8 Glyconos street, 106 75 Athens, Greece
    Eur Cytokine Netw 17:137-41. 2006
    ..Our results suggest that WCH may be associated with decreased fibrinolytic potential and endothelial dysfunction, indicating that WCH may not be a completely harmless trait...
  8. ncbi request reprint Stent treatment of an aortocoronary dissection during percutaneous coronary intervention. A case report and brief literature review
    Dimitris P Papadopoulos
    Dept of Cardiology, Laiko Hospital of Athens, Greece
    Acta Cardiol 61:119-21. 2006
    ..We describe a patient, in whom retrograde aortic dissection appeared during percutaneous coronary intervention to the right coronary artery, which was successfully treated by a 4-stent implantation...
  9. ncbi request reprint Adiponectin and resistin plasma levels in healthy individuals with prehypertension
    Dimitrios P Papadopoulos
    Department of Cardiology, Laiko Hospital, Athens, Greece
    J Clin Hypertens (Greenwich) 7:729-33. 2005
    ..These findings may represent another possible mechanism that may increase the cardiovascular risk in this special group of patients, needing further investigation...
  10. doi request reprint Depression masked as paroxysmal hypertension episodes
    Dimitris P Papadopoulos
    Hypertension Clinic, Laiko University Hospital, 24 Agiou Ioannou Theologou Street, 15561 Athens, Greece
    Blood Press 19:16-9. 2010
    ..The use of drugs effective for treatment of panic disorder can also be helpful in managing those patients...
  11. ncbi request reprint Coexistence of anomalous origin of the coronary arteries and severe aortic regurgitation in Marfan syndrome
    Dimitris P Papadopoulos
    Department of Cardiology, Laiko Hospital of Athens, 6 8 Glykonos Street, 106 75 Athens, Greece
    Clin Rheumatol 25:737-8. 2006
    ..A case report of abnormal origin of the left and right coronary arteries from the right sinus of valsalva with severe aortic regurgitation in Marfan syndrome is presented in this paper...
  12. doi request reprint Masked hypertension and atherogenesis: the impact on adiponectin and resistin plasma levels
    Dimitris P Papadopoulos
    Department of Cardiology, Hypertension Clinic, Laiko Hospital, Athens, Greece
    J Clin Hypertens (Greenwich) 11:61-5. 2009
    ..This observation may have prognostic significance for future cardiovascular events in patients with MH...
  13. doi request reprint On target to dual block RAS?
    Dimitris P Papadopoulos
    Hypertension Clinic, Department of Cardiology, Laiko Hospital, Athens, Greece
    Angiology 60:739-49. 2009
    ..In some clinical settings, combined therapy angiotensin-converting enzyme inhibitors with angiotensin receptor blocker (double blockade of the renin-angiotensin- aldosterone system) may appear the most effective...
  14. doi request reprint Is it time to treat prehypertension?
    Dimitris P Papadopoulos
    Hypertension Clinic, Department of Cardiology, Laiko Hospital, 39 Karneadou Street, Athens, Greece
    Hypertens Res 31:1681-6. 2008
    ..In this review, we discuss the options for pharmacologic intervention of prehypertension, with a focus on the TROPHY trial results...
  15. doi request reprint Low-dose fixed combination of bisoprolol/hydrochlorothiazide as first line for hypertension: a review of the rationale and clinical evidence
    Dimitris P Papadopoulos
    Hypertension and Cardiovascular Research Clinic, Georgetown University Veterans Affairs Medical Center, Washington, DC 20422, USA
    Angiology 60:601-7. 2009
    ..This review summarizes the beneficial effect of low-dose bisoprolol/ hydrochlorothiazide combination in the treatment of patients with stage I and II hypertension...
  16. doi request reprint Aggressive blood pressure control and stroke prevention: role of calcium channel blockers
    Dimitris P Papadopoulos
    Hypertension Clinic, Department of Cardiology, Laiko Hospital, Athens, Greece
    J Hypertens 26:844-52. 2008
    ..They can also be used as first-line therapy for older, stroke-prone hypertensive patients. The aim of this review is to summarize the role of CCBs in the prevention of stroke...
  17. doi request reprint Metoprolol succinate combination in the treatment of hypertension
    Dimitris P Papadopoulos
    Georgetown University Medical Center, Georgetown, Washington, D C and Veterans Affairs Medical Center, Washington, DC 20422, USA
    Angiology 60:608-13. 2009
    ..The aim of this review was to determine the pharmacokinetic and pharmacodynamic properties of metoprolol succinate and to apply those properties in combination with other drugs mainly diuretics in the treatment of hypertension...
  18. doi request reprint Adiponectin--insulin and resistin plasma levels in young healthy offspring of patients with essential hypertension
    D P Papadopoulos
    Hypertension Clinic, Department of Cardiology, Laiko Hospital, Athens, Greece
    Blood Press 17:50-4. 2008
    ....
  19. ncbi request reprint Role of perindopril in the prevention of stroke
    Dimitris P Papadopoulos
    Hypertension and Cardiology Clinic, Laiko General Hospital, 6 8 Glykonos Street, Athens, Grecce
    Recent Pat Cardiovasc Drug Discov 1:283-9. 2006
    ....
  20. ncbi request reprint Metabolic side effects and cardiovascular events of diuretics: should a diuretic remain the first choice therapy in hypertension treatment? The case of yes
    Dimitris P Papadopoulos
    Hypertension and Cardiovascular Research Clinic, Georgetown University, Washington, DC, USA
    Clin Exp Hypertens 29:503-16. 2007
    ..At the end of the article, we highlighted the differences regarding the prescription of diuretics between the recently published American and European Guidelines of hypertension...
  21. ncbi request reprint Masked hypertension definition, impact, outcomes: a critical review
    Dimitris P Papadopoulos
    Hypertension Clinic, Cardiology Department, Laiko Hospital, Athens, Greece
    J Clin Hypertens (Greenwich) 9:956-63. 2007
    ..The aim of this review was to define the entity of MH, to describe its prevalence in the general population, and to discuss its correlation with cardiovascular events...
  22. ncbi request reprint Changes in metalloproteinases in healthy normotensive patients with high-normal blood pressure
    Dimitrios P Papadopoulos
    Department of Cardiology, Laiko Hospital, 6 8 Glykonos Street, Athens, Greece
    Eur Cytokine Netw 16:211-4. 2005
    ....
  23. ncbi request reprint Complete heart block in a patient with systemic sclerosis
    I Moyssakis
    Department of Cardiology, Laiko Hospital of Athens, 17 Agiou Thomas St Goudi, 15727, Athens, Greece
    Clin Rheumatol 25:551-2. 2006
    ..The patient underwent implantation of a permanent pacemaker...
  24. ncbi request reprint Right coronary ostium agenesis with absence of the right coronary artery: a rare case of non-ST elevation coronary syndrome
    Dimitris P Papadopoulos
    Department of Cardiology, Laiko Hospital of Athens, 106 75 Athens, Greece
    Clin Anat 19:345-6. 2006
    ..A review of the literature indicates this to be an extremely rare case...
  25. doi request reprint Hypertension crisis
    Dimitris P Papadopoulos
    Hypertension Clinic, Laiko University Hospital, Athens, Greece
    Blood Press 19:328-36. 2010
    ..The aim of this review is to summarize the details regarding the definition-impact, causes, clinical condition and management of hypertensive crises...
  26. doi request reprint Masked hypertension unfavourably affects haemostasis parameters
    D P Papadopoulos
    ESH Excellent Center of Hypertension, Laiko Univesity Hospital, Athens, Greece
    Blood Press 20:218-21. 2011
    ..This observation may have prognostic significance for future cardiovascular events in subjects with MH and needs further investigation...
  27. ncbi request reprint Coronary artery aneurysms and coronary artery fistula as a cause of angina pectoris
    Dimitris P Papadopoulos
    Department of Cardiology, Laiko Hospital of Athens, Athens, Greece
    Clin Anat 18:77-8. 2005
    ..Coronary artery fistulae are infrequent congenital anomalies. A extremely rare case report of combination of coronary artery aneurysms and coronary artery fistula is presented with a brief literature review...
  28. ncbi request reprint Left atrial systolic function in primary and familial amyloidosis: assessment from left atrial volume change
    Ioannis Moyssakis
    Department of Cardiology, Laiko Hospital, Athens, Greece
    Clin Cardiol 27:528-32. 2004
    ..This is most likely due to the restrictive left ventricular physiology possibly associated with depressed LA contractility in the former...
  29. ncbi request reprint Clinical significance of matrix metalloproteinases activity in acute myocardial infarction
    D P Papadopoulos
    Department of Cardiology, Laiko Hospital of Athens, 6 8 Glykonos Street, 106 75 Athens, Greece
    Eur Cytokine Netw 16:152-60. 2005
    ..00013). In acute MI patients, increased MMP-1, with no change in TIMP-1, is associated with left ventricular dysfunction and dilatation, suggesting that increased collagenolytic activity contributes to loss of LV function...
  30. ncbi request reprint Acute myocardial infarction due to spontaneous dissection of the right coronary artery in a young male
    Dimitris P Papadopoulos
    Department of Cardiology, Laiko Hospital of Athens, Greece
    Cardiovasc Intervent Radiol 27:536-7. 2004
    ..Because of a spiral form of dissection and the TIMI 3 flow grade, our patient was treated medically and repeat coronary angiography 6 months later was decided...
  31. ncbi request reprint Effect of angiotensin-converting enzyme inhibitor on collagenolytic enzyme activity in patients with acute myocardial infarction
    D P Papadopoulos
    Department of Cardiology, Laiko Hospital, Athens, Greece
    Drugs Exp Clin Res 30:55-65. 2004
    ..5% and infarct size was small to medium. In conclusion, early initiation of ACEI treatment reduces collagenolytic activity. This effect may be considered an alternative mechanism for beneficial effects on postinfarction remodeling...
  32. ncbi request reprint Polyarteritis nodosa and hypertrophic obstructive cardiomyopathy. A true association?
    Dimitris P Papadopoulos
    Department of Cardiology, Laiko Hospital of Athens, Athens, Greece
    Clin Rheumatol 23:57-8. 2004
    ..This is the first report of hypertrophic obstructive cardiomyopathy developing in a patient with polyarteritis nodosa. Further studies should examine whether a true association exists...
  33. ncbi request reprint Human soluble leptin receptor number in healthy normotensive individuals with high normal blood pressure
    Dimitrios P Papadopoulos
    Department of Cardiology, Laiko Hospital, and Laboratory of Experimental Surgery and Surgical Research, Athens Medical School, Athens, Greece
    Am J Hypertens 18:1001-4. 2005
    ..The aim of our study was to determine the human soluble leptin receptor number in healthy normotensive subjects with high normal BP and to compare these findings to those of healthy normotensive individuals with normal BP levels...
  34. ncbi request reprint Left ventricular end-systolic stress/diameter relation as a contractility index and as a predictor of survival. Independence of preload after normalization for end-diastolic diameter
    Ioannis Moyssakis
    Department of Cardiology, Laiko Hospital of Athens, 17 Agiou Thomas Street, GR 157 27 Goudi, Athens, Greece
    Heart Vessels 20:191-8. 2005
    ..The normalization of the slope eliminates its dependence on PL and improves the sensitivity in assessing decreased contractility, although it slightly decreases its prognostic value...
  35. ncbi request reprint Anomalous left coronary artery arising from the right sinus of valsalva as a cause of ventricular tachycardia
    Dimitris P Papadopoulos
    Department of Cardiology, Laiko Hospital of Athens, Greece
    Acta Cardiol 60:65-7. 2005
    ..This rare case was discovered during coronary angiography for the evaluation of the patient, after restoration of symptomatic ventricular tachycardia...
  36. ncbi request reprint Time-dependent changes in the expression of thyroid hormone receptor alpha 1 in the myocardium after acute myocardial infarction: possible implications in cardiac remodelling
    Constantinos Pantos
    Department of Pharmacology, University of Athens, 75 Mikras Asias Avenue, 11527 Goudi, Athens, Greece
    Eur J Endocrinol 156:415-24. 2007
    ..Furthermore, down-regulation of TR beta 1 also contributes to fetal phenotypic changes. alpha1-adrenergic signalling is, at least in part, involved in this response...
  37. ncbi request reprint Thyroid hormone attenuates cardiac remodeling and improves hemodynamics early after acute myocardial infarction in rats
    Constantinos Pantos
    Department of Pharmacology, University of Athens, 75 Mikras Asias Avenue, 11527 Goudi, Athens, Greece
    Eur J Cardiothorac Surg 32:333-9. 2007
    ..TH regulates important structural and regulatory proteins in the myocardium including myosin isoform expression and calcium cycling proteins...
  38. ncbi request reprint Trimetazidine protects isolated rat hearts against ischemia-reperfusion injury in an experimental timing-dependent manner
    Costantinos Pantos
    Department of Pharmacology, University of Athens, Athens, Greece
    Basic Res Cardiol 100:154-60. 2005
    ..In conclusion, preischemic administration of TMZ protects against I/R injury while TMZ given only at reperfusion accelerates recovery of function without reducing the extent of injury...
  39. doi request reprint Dose-dependent effects of thyroid hormone on post-ischemic cardiac performance: potential involvement of Akt and ERK signalings
    Iordanis Mourouzis
    Department of Pharmacology, University of Athens, 75 Mikras Asias Ave, 11527 Goudi, Athens, Greece
    Mol Cell Biochem 363:235-43. 2012
    ..In conclusion, TH appears to have a dose-dependent bimodal effect on post-ischemic cardiac performance and this effect may, at least in part, be mediated by a distinct pattern of activation of Akt and ERK signaling...
  40. ncbi request reprint Enhanced tolerance of the rat myocardium to ischemia and reperfusion injury early after acute myocardial infarction
    Constantinos Pantos
    Dept of Pharmacology, University of Athens, 75 Mikras Asias Ave, 11527 Goudi, Athens, Greece
    Basic Res Cardiol 102:327-33. 2007
    ..4-fold less in AMI, P < 0.05. In conclusion, the post-infarcted heart seems to be resistant to ischemiareperfusion injury and heat shock protein 70 and 27 may be involved in this response...
  41. doi request reprint Acute T3 treatment protects the heart against ischemia-reperfusion injury via TRα1 receptor
    Constantinos Pantos
    Department of Pharmacology, University of Athens, 75 Mikras Asias Ave, 11527 Goudi, Athens, Greece
    Mol Cell Biochem 353:235-41. 2011
    ..T3 can exert this beneficial effect on ischemic myocardium at a dose that has no effects on non-ischemic myocardium. Acute T3-limiting effect on reperfusion injury is mediated, at least in part, via TRα1 receptor...
  42. doi request reprint Thyroid hormone improves the mechanical performance of the post-infarcted diabetic myocardium: a response associated with up-regulation of Akt/mTOR and AMPK activation
    Iordanis Mourouzis
    Department of Pharmacology, University of Athens, 75 Mikras Asias Ave, 11527 Goudi, Athens, Greece
    Metabolism 62:1387-93. 2013
    ..Thus, this study explored the potential effects of TH treatment on the functional status of the postinfarcted diabetic myocardium. Diabetic patients have worse prognosis after acute myocardial infarction (AMI)...
  43. doi request reprint Inhibition of thyroid hormone receptor α1 impairs post-ischemic cardiac performance after myocardial infarction in mice
    Iordanis Mourouzis
    Department of Pharmacology, University of Athens, Athens, Greece
    Mol Cell Biochem 379:97-105. 2013
    ..AMI induces downregulation of thyroid hormone signaling and pharmacological inhibition of TRα1 further depresses post-ischemic cardiac function. p38 MAPK and PLB may, at least in part, be involved in this response...
  44. ncbi request reprint Effects of acute and chronic cadmium administration on the vascular reactivity of rat aorta
    Vassilios Tzotzes
    Department of Experimental Pharmacology, Medical School, University of Athens, 75 Mikras Asias Str, Goudi, GR 11527, Athens, Greece
    Biometals 20:83-91. 2007
    ..The contractile response levels of the E+ aortic rings to PE and ACh showed no statistically significant difference...
  45. doi request reprint Long-term thyroid hormone administration reshapes left ventricular chamber and improves cardiac function after myocardial infarction in rats
    Constantinos Pantos
    Dept of Pharmacology, University of Athens, 75 Mikras Asias Ave, Goudi, 11527, Athens, Greece
    Basic Res Cardiol 103:308-18. 2008
    ..98 (0.03) for SHAM, 1.52 (0.05) for AMI and 1.72(0.02) for AMI-THYR, P < 0.05. In conclusion, long-term TH administration immediately after AMI results in sustained improvement of cardiac haemodynamics...
  46. ncbi request reprint Dronedarone administration prevents body weight gain and increases tolerance of the heart to ischemic stress: a possible involvement of thyroid hormone receptor alpha1
    Constantinos Pantos
    Department of Pharmacology, University of Athens, Athens, Greece
    Thyroid 15:16-23. 2005
    ..This is accompanied by a reduction in body weight because of the suppression of food intake. TRs might prove novel pharmacologic targets for the treatment of cardiovascular illnesses...
  47. doi request reprint Morphine administration at reperfusion fails to improve postischaemic cardiac function but limits myocardial injury probably via heat-shock protein 27 phosphorylation
    Iordanis Mourouzis
    Department of Pharmacology, Attikon Hospital, University of Athens School of Medicine, Athens, Greece
    Eur J Anaesthesiol 26:572-81. 2009
    ..This is of important clinical value, as morphine is used routinely in cardiovascular anaesthesia and in the emergency management of cardiac infarction...
  48. ncbi request reprint Thyroid hormone changes cardiomyocyte shape and geometry via ERK signaling pathway: potential therapeutic implications in reversing cardiac remodeling?
    C Pantos
    Department of Pharmacology, University of Athens, 75 Mikras Asias Ave, Goudi 11527, Athens, Greece
    Mol Cell Biochem 297:65-72. 2007
    ..In conclusion, T(3) induced changes in cardiomyocyte shape and geometry involve the ERK kinase signaling. This response is independent of the effects of T(3) on cell size and protein synthesis...
  49. doi request reprint Thyroid hormone can favorably remodel the diabetic myocardium after acute myocardial infarction
    Christos Kalofoutis
    Department of Pharmacology, University of Athens, 75 Mikras Asias Ave, 11527, Goudi, Athens, Greece
    Mol Cell Biochem 345:161-9. 2010
    ..Acute myocardial infarction in diabetic rats results in TH receptor down-regulation with important physiological consequences. TH treatment prevents this response and improves cardiac hemodynamics...
  50. doi request reprint Dose-dependent effects of sildenafil on post-ischaemic left ventricular function in the rat isolated heart
    Theofilos M Kolettis
    Department of Cardiology, University of Ioannina, Ioannina, Greece
    J Pharm Pharmacol 62:346-51. 2010
    ..We have explored the effects of two acute and one chronic administration regimen on left ventricular function...
  51. doi request reprint Thyroid hormones alterations during acute liver failure: possible underlying mechanisms and consequences
    Georgia Kostopanagiotou
    2nd Department of Anesthesiology, Attikon Hospital, University of Athens School of Medicine, Rimini 1 Str, Chaidari, Athens, Greece
    Endocrine 36:198-204. 2009
    ..The downregulation of T(4) and T(3) levels during ALF seems to correlate well with the severity of disease. This downregulation related to inflammation and oxidative stress and resulted in changes in myocardial thyroid receptors...
  52. ncbi request reprint Effects of hyper- and hypothyroidism on acetylcholinesterase, (Na(+), K (+))- and Mg ( 2+ )-ATPase activities of adult rat hypothalamus and cerebellum
    Haris Carageorgiou
    Department of Experimental Pharmacology, Medical School, University of Athens, Athens, Greece
    Metab Brain Dis 22:31-8. 2007
    ..Moreover, the above TH-induced changes may affect the monoamine neurotransmitter systems...
  53. ncbi request reprint Comparative effects of acute vs. chronic oral amiodarone treatment during acute myocardial infarction in rats
    Theofilos M Kolettis
    Department of Cardiology, University of Ioannina, 1 Stavrou Niarxou Avenue, 45110 Ioannina, Greece
    Europace 9:1099-104. 2007
    ..This study investigated whether chronic and acute amiodarone treatment has differential effects on ventricular arrhythmogenesis during acute myocardial infarction in rats...
  54. doi request reprint Thyroid hormone improves postischaemic recovery of function while limiting apoptosis: a new therapeutic approach to support hemodynamics in the setting of ischaemia-reperfusion?
    Constantinos Pantos
    Department of Pharmacology, University of Athens, 75 Mikras Asias Ave, Goudi, Athens, Greece
    Basic Res Cardiol 104:69-77. 2009
    ..This may constitute a paradigm of a positive inotropic agent with anti-apoptotic action suitable for supporting hemodynamics in the clinical setting of ischaemia-reperfusion...
  55. ncbi request reprint Thyroid hormone is a critical determinant of myocardial performance in patients with heart failure: potential therapeutic implications
    Constantinos Pantos
    Department of Pharmacology, University of Athens, 75 Mikras Asias Avenue, 11527 Goudi, Athens, Greece
    Eur J Endocrinol 157:515-20. 2007
    ..The present study further explores whether thyroid hormone alterations are correlated with the functional status of the myocardium in patients with heart failure...
  56. ncbi request reprint Thyroxine pretreatment increases basal myocardial heat-shock protein 27 expression and accelerates translocation and phosphorylation of this protein upon ischaemia
    Constantinos Pantos
    Department of Pharmacology, University of Athens, 75 Mikras Asias Avenue, 11527 Goudi, Athens, Greece
    Eur J Pharmacol 478:53-60. 2003
    ..This effect might be of important therapeutic relevance...
  57. ncbi request reprint High glucose protects embryonic cardiac cells against simulated ischemia
    Vassiliki Malliopoulou
    Department of Pharmacology, University of Athens, 75 Mikras Asias Ave, 11527 Goudi, Athens, Greece
    Mol Cell Biochem 284:87-93. 2006
    ..Although this protective effect is associated with translocation of PKCepsilon and increased glucose uptake, it was abrogated only by inhibition of glycolysis...
  58. doi request reprint Thyroid hormone and "cardiac metamorphosis": potential therapeutic implications
    Constantinos Pantos
    Department of Pharmacology, University of Athens, 75 Mikras Asias Ave, 11527 Goudi, Athens, Greece
    Pharmacol Ther 118:277-94. 2008
    ..At present, the therapeutic potential and efficacy of TH in the treatment of cardiac diseases await evaluation in large clinical trials...
  59. doi request reprint Rebuilding the post-infarcted myocardium by activating 'physiologic' hypertrophic signaling pathways: the thyroid hormone paradigm
    Constantinos Pantos
    Department of Pharmacology, University of Athens, School of Medicine, 75 Mikras Asias Avenue, 11527 Goudi, Athens, Greece
    Heart Fail Rev 15:143-54. 2010
    ..TH may constitute a new therapeutic option for mending the ischemic myocardium...
  60. doi request reprint New insights into the role of thyroid hormone in cardiac remodeling: time to reconsider?
    Constantinos Pantos
    Department of Pharmacology, University of Athens, 75 Mikras Asias Ave, 11527, Goudi, Athens, Greece
    Heart Fail Rev 16:79-96. 2011
    ..While preliminary clinical studies provide encouraging results, the potential and efficacy of TH in the treatment of heart disease still await evaluation in large clinical trials...
  61. ncbi request reprint Possible implications of leptin, adiponectin and ghrelin in the regulation of energy homeostasis by thyroid hormone
    Alexander Kokkinos
    1st Department of Propaedeutic Medicine, Laiko General Hospital, University of Athens Medical School, 11527, Goudi, Athens, Greece
    Endocrine 32:30-2. 2007
    ..05 and P = 0.03, respectively). In conclusion, leptin seems mainly to be involved in the thyroid hormone effects on energy homeostasis. Ghrelin and adiponectin may serve a compensatory physiological role in hypothyroidism...
  62. doi request reprint Thyroid hormone as a therapeutic option for treating ischaemic heart disease: from early reperfusion to late remodelling
    Constantinos Pantos
    Department of Pharmacology, University of Athens, School of Medicine, 75 Mikras Asias Ave, 11527 Goudi, Athens, Greece
    Vascul Pharmacol 52:157-65. 2010
    ..Thyroid analogs have already been developed and may allow TH use in clinical practice. However, the efficacy of TH in the treatment of cardiac diseases is now awaiting to be tested in large clinical trials...
  63. ncbi request reprint Changes in antioxidant status, protein concentration, acetylcholinesterase, (Na+,K+)-, and Mg2+ -ATPase activities in the brain of hyper- and hypothyroid adult rats
    Haris Carageorgiou
    Department of Experimental Pharmacology, Medical School, University of Athens, Athens, Greece
    Metab Brain Dis 20:129-39. 2005
    ..Such changes of the enzyme activities may differentially modulate the brain intracellular Mg2+, neural excitability, as well as the uptake and release of biogenic amines...
  64. doi request reprint Thyroid hormone and recovery of cardiac function in patients with acute myocardial infarction: a strong association?
    Ioannis Lymvaios
    Department of Pharmacology, University of Athens, 75 Mikras Asias Avenue, 11527 Goudi, Athens, Greece
    Eur J Endocrinol 165:107-14. 2011
    ..Previous experimental studies have provided evidence of potential implication of TH signaling in post-ischemic recovery of cardiac function...
  65. doi request reprint Thyroid hormone and myocardial ischaemia
    Constantinos Pantos
    Department of Pharmacology, University of Athens, 75 Mikras Asias Avenue, 11527 Goudi, Athens, Greece
    J Steroid Biochem Mol Biol 109:314-22. 2008
    ..Thyroid hormone or analogs may prove new therapeutic agents for treating ischaemic heart disease...
  66. ncbi request reprint The differential impact of volatile and intravenous anaesthetics on stress response in the swine
    Georgia Kostopanagiotou
    2nd Department of Anaesthesiology, School of Medicine, University of Athens, Attikon Hospital, Athens, Greece
    Hormones (Athens) 9:67-75. 2010
    ..To compare the effects of various anaesthetics on stress response in the presence and absence of surgical stimulation...
  67. ncbi request reprint Protection of the abnormal heart
    Constantinos Pantos
    Department of Pharmacology, University of Athens, 75 Mikras Asias Avenue, 11527 Goudi, Athens, Greece
    Heart Fail Rev 12:319-30. 2007
    ..With this evidence in mind, the present review will focus on the response of the abnormal heart to ischemia and reperfusion, the possible underlying mechanisms, and potential cardioprotective strategies...
  68. ncbi request reprint Left atrial systolic reserve in idiopathic vs. ischaemic-dilated cardiomyopathy
    I Moyssakis
    Laico General Hospital of Athens, Athens, Greece
    Eur J Clin Invest 35:355-61. 2005
    ..It was hypothesized that the findings would be similar with regards LA systolic reserve...
  69. ncbi request reprint Severe aortic regurgitation in von Recklinghausen's disease--a case report
    N J Pantazopoulos
    Department of Cardiology, Laiko Hospital, Athens, Greece
    Angiology 56:225-7. 2005
    ....
  70. ncbi request reprint Left atrial systolic function is depressed in idiopathic and preserved in ischemic dilated cardiomyopathy
    F Triposkiadis
    University of Thessaly, Faculty of Health Sciences, School of Medicine, Larissa, Greece
    Eur J Clin Invest 29:905-12. 1999
    ..Left atrial systolic dysfunction, unexplained by altered loading conditions, has been reported in idiopathic dilated cardiomyopathy suggesting left atrial involvement in the myopathic process...
  71. ncbi request reprint Assessment of the left ventricular diastolic reserve in essential hypertension: the acute saline load test
    F Triposkiadis
    University of Thessaly, Department of Cardiology, Larissa, Greece
    Eur J Clin Invest 31:690-7. 2001
    ....
  72. doi request reprint Functional effects of local thyroid hormone administration after sciatic nerve injury in rats
    Ioannis Papakostas
    Pharmacology Department, Medical School of Athens, Athens, Greece
    Microsurgery 29:35-41. 2009
    ..In conclusion, T3 seems to accelerate the return of sensory function after complete transection of the sciatic nerves in Lewis rats without a significant effect on motor nerve recovery...
  73. pmc Systolic and diastolic function in middle aged patients with sickle beta thalassaemia. An echocardiographic study
    I Moyssakis
    Cardiology Department, Laiko General Hospital, Athens, Greece
    Postgrad Med J 81:711-4. 2005
    ..To evaluate the right and left ventricular systolic and diastolic function in middle aged patients with sickle beta thalassaemia...
  74. ncbi request reprint Spatial QRS-T angle: association with diabetes and left ventricular performance
    Ch Voulgari
    Laiko Hospital, Athens University Medical School, Athens, Greece
    Eur J Clin Invest 36:608-13. 2006
    ..The prognostic importance of the higher spQRS-T angle values in subjects with diabetes remains to be evaluated in prospective studies...
  75. doi request reprint Myocardial performance and aortic elasticity are impaired in patients with ankylosing spondylitis
    I Moyssakis
    Cardiology Department, Laiko General Hospital, Athens, Greece
    Scand J Rheumatol 38:216-21. 2009
    ..To measure aortic stiffness and global left ventricular (LV) function in patients with ankylosing spondylitis (AS) and no clinical evidence of heart disease...
  76. ncbi request reprint Aortic stiffness in systemic sclerosis is increased independently of the extent of skin involvement
    I Moyssakis
    Laikon Hospital, Department of Cardiology, 17 Agiou Thomas Street, GR 15727 Goudi, Athens, Greece
    Rheumatology (Oxford) 44:251-4. 2005
    ..To study the stiffness of large arteries in relation to the extent of skin and lung fibrosis, aortic distensibility was examined in patients with diffuse and limited systemic sclerosis (SSc)...
  77. ncbi request reprint Hypertrophic cardiomyopathy in systemic sclerosis. A report of two cases
    I Moyssakis
    Department of Cardiology, Laiko Hospital, 6 8 Glykonos Street, 106 75 Athens, Greece
    Clin Rheumatol 25:404-6. 2006
    ..However, further studies should examine whether a true association exists...
  78. ncbi request reprint Aortic distensibility is reduced in subjects with type 2 diabetes and cardiac autonomic neuropathy
    N Tentolouris
    Athens University Medical School, Laiko Hospital, Athens, Greece
    Eur J Clin Invest 33:1075-83. 2003
    ..Cardiac autonomic neuropathy is common in subjects with diabetes. However, the relationship between the elastic properties of the aorta and autonomic neuropathy has not been studied to date in subjects with type 2 diabetes...
  79. ncbi request reprint Is the heart affected in primary Sjögren's syndrome? An echocardiographic study
    V A Vassiliou
    Department of Pathophysiology, University of Athens School of Medicine, Athens, Greece
    Clin Exp Rheumatol 26:109-12. 2008
    ..To evaluate whether patients with primary Sjögren's syndrome without overt cardiac disease have echocardiographic abnormalities and their relation with clinical and laboratory data...
  80. doi request reprint Impaired aortic elastic properties in patients with systemic sarcoidosis
    I Moyssakis
    Department of Cardiology, Medical School, National University of Athens, Laiko Hospital, Athens, Greece
    Eur J Clin Invest 38:82-9. 2008
    ..In addition, we examined potential associations between AoD and clinical, respiratory and echocardiographic findings in patients with Sar...
  81. doi request reprint The presence of anti-centromere antibodies may predict progression of estimated pulmonary arterial systolic pressure in systemic sclerosis
    C Kampolis
    Department of Pathophysiology, University of Athens School of Medicine, Athens, Greece
    Scand J Rheumatol 37:278-83. 2008
    ..To define the risk factors associated with a relatively rapid increase in estimated pulmonary arterial systolic pressure (PASP) in patients with systemic sclerosis (SSc)...
  82. ncbi request reprint Treatment of symptomatic acute internal mammary artery graft dissection by percutaneous stent placement
    Dimitris P Papadopoulos
    Int J Cardiol 101:137-8. 2005