Brian D Moseley

Summary

Publications

  1. doi request reprint The effects of lacosamide on depression and anxiety in patients with epilepsy
    Brian D Moseley
    Department of Neurology and Rehabilitation Medicine, University of Cincinnati, Cincinnati, OH, USA Electronic address
    Epilepsy Res 110:115-8. 2015
  2. doi request reprint How long is long enough? The utility of prolonged inpatient video EEG monitoring
    Brian D Moseley
    Department of Neurology and Rehabilitation Medicine, University of Cincinnati, Cincinnati, OH, USA Electronic address
    Epilepsy Res 109:9-12. 2015
  3. doi request reprint Increased cerebral oxygenation precedes generalized tonic clonic seizures
    Brian D Moseley
    Department of Neurology and Rehabilitation Medicine, University of Cincinnati, Cincinnati, OH, USA Electronic address
    Epilepsy Res 108:1671-4. 2014
  4. doi request reprint Peri-ictal QTc changes are not associated with hypoxemia
    Brian D Moseley
    Department of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA Electronic address
    Epilepsy Res 108:982-5. 2014
  5. doi request reprint Refractory status epilepticus treated with trigeminal nerve stimulation
    Brian D Moseley
    Department of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA Electronic address
    Epilepsy Res 108:600-3. 2014
  6. doi request reprint Characteristics of postictal generalized EEG suppression in children
    Brian D Moseley
    Department of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA
    Epilepsy Res 106:123-7. 2013
  7. pmc Early onset epilepsy is associated with increased mortality: a population-based study
    Brian D Moseley
    Divisions of Epilepsy and Clinical Neurophysiology, Department of Neurology, UCLA, Los Angeles, CA, USA
    Epilepsy Res 105:410-4. 2013
  8. doi request reprint Periictal cerebral tissue hypoxemia: a potential marker of SUDEP risk
    Brian D Moseley
    Department of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, California, USA
    Epilepsia 53:e208-11. 2012
  9. doi request reprint Standardized sign-out improves completeness and perceived accuracy of inpatient neurology handoffs
    Brian D Moseley
    Department of Neurology, Mayo Clinic, Rochester, MN, USA
    Neurology 79:1060-4. 2012
  10. doi request reprint Electrocardiographic and oximetric changes during partial complex and generalized seizures
    Brian D Moseley
    Department of Neurology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Epilepsy Res 95:237-45. 2011

Detail Information

Publications23

  1. doi request reprint The effects of lacosamide on depression and anxiety in patients with epilepsy
    Brian D Moseley
    Department of Neurology and Rehabilitation Medicine, University of Cincinnati, Cincinnati, OH, USA Electronic address
    Epilepsy Res 110:115-8. 2015
    ..64 ± 2.78, p < 0.001). NDDI-E and GAD-7 scores pre- and post-lacosamide initiation were not significantly affected by a history of mood disorders, concomitant psychiatric medications, or concomitant AEDs with mood-stabilizing effects...
  2. doi request reprint How long is long enough? The utility of prolonged inpatient video EEG monitoring
    Brian D Moseley
    Department of Neurology and Rehabilitation Medicine, University of Cincinnati, Cincinnati, OH, USA Electronic address
    Epilepsy Res 109:9-12. 2015
    ..5 days, it did not predict outcomes well (AUC 0.52, sensitivity 0.55, specificity 0.5). Based on our data, prolonging VEM appears useful for the proper classification and localization of ES. ..
  3. doi request reprint Increased cerebral oxygenation precedes generalized tonic clonic seizures
    Brian D Moseley
    Department of Neurology and Rehabilitation Medicine, University of Cincinnati, Cincinnati, OH, USA Electronic address
    Epilepsy Res 108:1671-4. 2014
    ..Three GTCS (42.9%) were marked by sustained cerebral hyperemia for ≥ 15 consecutive readings. Our results suggest increased cerebral blood flow could be non-invasively used to predict seizure occurrence...
  4. doi request reprint Peri-ictal QTc changes are not associated with hypoxemia
    Brian D Moseley
    Department of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA Electronic address
    Epilepsy Res 108:982-5. 2014
    ..All examined parameters of QTc lengthening and shortening were not associated with peri-ictal hypoxemia. This suggests that factors other than hypoxia result in peri-ictal cardiac repolarization abnormalities. ..
  5. doi request reprint Refractory status epilepticus treated with trigeminal nerve stimulation
    Brian D Moseley
    Department of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA Electronic address
    Epilepsy Res 108:600-3. 2014
    ..Given our patient's quick response, such benefit may have arisen from EEG-desynchronization. If confirmed in larger studies, eTNS could one day be considered along with other adjuvant treatments for RSE. ..
  6. doi request reprint Characteristics of postictal generalized EEG suppression in children
    Brian D Moseley
    Department of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA
    Epilepsy Res 106:123-7. 2013
    ..9 ± 1.4, p=0.45), or hypoxemia (3.4 ± 1.5 versus 2.4 ± 1.3, p=0.051). Based on our data, PGES is not rare in children. Children with PGES may be at greater risk for SUDEP as measured by the SUDEP-7 Inventory...
  7. pmc Early onset epilepsy is associated with increased mortality: a population-based study
    Brian D Moseley
    Divisions of Epilepsy and Clinical Neurophysiology, Department of Neurology, UCLA, Los Angeles, CA, USA
    Epilepsy Res 105:410-4. 2013
    ..001; MR 54/1000 person years versus 2.7/1000 person year; SMR 46.55 versus 7.22). Given that only 1/8 early onset epilepsy deaths was seizure-related, mortality appears to be more affected by underlying etiology. ..
  8. doi request reprint Periictal cerebral tissue hypoxemia: a potential marker of SUDEP risk
    Brian D Moseley
    Department of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, California, USA
    Epilepsia 53:e208-11. 2012
    ..8) versus patients without recorded desaturations (4.3 ± 0.5, p = 0.08). Larger studies are needed to determine the value of cerebral oximetry in the identification of patients at risk of SUDEP...
  9. doi request reprint Standardized sign-out improves completeness and perceived accuracy of inpatient neurology handoffs
    Brian D Moseley
    Department of Neurology, Mayo Clinic, Rochester, MN, USA
    Neurology 79:1060-4. 2012
    ..Accordingly, we implemented a standardized sign-out process on our inpatient neurology services and assessed its effect on completeness and perceived accuracy of handoffs...
  10. doi request reprint Electrocardiographic and oximetric changes during partial complex and generalized seizures
    Brian D Moseley
    Department of Neurology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Epilepsy Res 95:237-45. 2011
    ..Ictal hypoxemia occurred in 25% of seizures and was associated with normal MRI (p=0.01), longer seizure duration (p=0.049), and ictal tachycardia (p=0.003). Such findings may have implications for understanding the pathogenesis of SUDEP...
  11. doi request reprint Early seizure termination in ictal asystole
    Brian D Moseley
    Department of Neurology, Mayo Clinic, Rochester, MN, USA
    Epilepsy Res 97:220-4. 2011
    ..4±13 s in IA, 67±28.9 s in ictal bradycardia, and 82.1±31.1 in non-bradycardic seizures. These were significantly different (ANOVA, p<0.02). This suggests cerebral hypoxia-ischemia favors seizure termination...
  12. doi request reprint How common is ictal hypoxemia and bradycardia in children with partial complex and generalized convulsive seizures?
    Brian D Moseley
    Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA
    Epilepsia 51:1219-24. 2010
    ..The purpose of this study was to determine the prevalence and risk factors for ictal hypoxemia (oxygen saturation <90%) and ictal bradycardia (heart rate < second percentile for age) in children during recorded seizures...
  13. doi request reprint Surgical outcomes for intractable epilepsy in children with epileptic spasms
    Brian D Moseley
    Department of Neurology, Mayo Clinic, Rochester, MN, USA
    J Child Neurol 27:713-20. 2012
    ..035 and .035, respectively). Favorable outcome was significantly associated with parent/caregiver report of improved postoperative developmental outcomes (P = .026)...
  14. doi request reprint Historic, clinical, and prognostic features of epileptic encephalopathies caused by CDKL5 mutations
    Brian D Moseley
    Department of Neurology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Pediatr Neurol 46:101-5. 2012
    ..Although no treatment eliminated seizures, topiramate, vigabatrin, and the ketogenic diet were most helpful at reducing seizure frequency...
  15. pmc Temporal lobe epilepsy in children
    Katherine C Nickels
    Divisions of Epilepsy and Child and Adolescent Neurology, Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA
    Epilepsy Res Treat 2012:849540. 2012
    ..Expedient workup and surgical intervention in these medically intractable cases are needed to maximize long-term developmental outcome...
  16. doi request reprint Generalized periodic epileptiform discharges in a child with Dravet syndrome
    Brian D Moseley
    Department of Neurology, Mayo Clinic, Rochester, Minnesota 55905, USA
    J Child Neurol 26:907-10. 2011
    ..The child was subsequently found to have a de novo mutation of the sodium channel, voltage-gated, type I, alpha subunit (SCN1A) gene consistent with Dravet syndrome...
  17. doi request reprint The cessation of continuous spike wave in slow-wave sleep following a temporal lobectomy
    Brian D Moseley
    Department of Neurology, Mayo Clinic, Rochester, MN, USA
    J Child Neurol 27:113-6. 2012
    ..The normalization of his sleep electroencephalogram following the anterior temporal lobectomy suggests that temporal lobe structures may be involved in the seizure network needed to generate continuous spike wave in slow-wave sleep...
  18. pmc A population-based study of long-term outcome of epilepsy in childhood with a focal or hemispheric lesion on neuroimaging
    Radhika Dhamija
    Department of Neurology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Epilepsia 52:1522-6. 2011
    ..To evaluate long-term seizure outcome in children with epilepsy and a focal or hemispheric neuroimaging abnormality...
  19. doi request reprint Long term outcomes in patients with preoperative generalized interictal epileptiform abnormalities following amygdalohippocampectomy
    Brian D Moseley
    Department of Neurology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Epilepsy Res 99:171-5. 2012
    ..Favorable outcomes were significantly associated with a history of auras prior to seizure onset (p=0.021), the absence of generalized IEDs on postoperative EEG (p=0.024), and the presence of focal slowing on postoperative EEG (p=0.045)...
  20. doi request reprint The treatment of ictal asystole with cardiac pacing
    Brian D Moseley
    Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA
    Epilepsia 52:e16-9. 2011
    ..005 falls/month (p = 0.001). Seizure-related fractures and motor vehicle accidents were also reduced following cardiac pacing. These findings may have implications in mitigating the potential morbidity associated with ictal asystole...
  21. doi request reprint N-methyl-D-aspartate receptor autoimmune encephalitis presenting with opsoclonus-myoclonus: treatment response to plasmapheresis
    Jonathan H Smith
    Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA
    Arch Neurol 68:1069-72. 2011
    ..To report the clinical, laboratory, and radiographic features and the response to plasmapheresis in a patient with encephalopathy, opsoclonus, and myoclonus whose cerebrospinal fluid was positive for N-methyl-D-aspartate receptor-IgG...
  22. doi request reprint Improving the prescription of folate to women receiving antiepileptic drugs
    Anumeha Sharma
    Department of Neurology and Rehabilitation Medicine, University of Cincinnati, Cincinnati, OH, USA Electronic address
    Epilepsy Res 112:27-30. 2015
    ..The rate of co-prescribing folate increased to 64.6% (p<0.001). Neurologists treating epilepsy continued to be more likely to prescribe folate (86.4%) than neurologists treating other conditions (46.2%, p=0.006). ..
  23. pmc Specific safety and tolerability considerations in the use of anticonvulsant medications in children
    Amy Z Crepeau
    Division of Epilepsy, Department of Neurology, Mayo Clinic, Rochester, MN, USA
    Drug Healthc Patient Saf 4:39-54. 2012
    ..This review will address issues of antiepileptic drug efficacy, tolerability and ease of use, pharmacokinetics, and drug-drug interactions in the pediatric age range...