Brian J Morris

Summary

Publications

  1. ncbi request reprint Circumcision rates in the United States: rising or falling? What effect might the new affirmative pediatric policy statement have?
    Brian J Morris
    School of Medical Sciences, University of Sydney, Sydney, NSW, Australia Electronic address
    Mayo Clin Proc 89:677-86. 2014
  2. pmc The Strong Protective Effect of Circumcision against Cancer of the Penis
    Brian J Morris
    School of Medical Sciences and Bosch Institute, Sydney Medical School, The University of Sydney, Sydney, NSW 2006, Australia
    Adv Urol 2011:812368. 2011
  3. pmc Genes influencing circadian differences in blood pressure in hypertensive mice
    Francine Z Marques
    Basic and Clinical Genomics Laboratory, School of Medical Sciences and Bosch Institute, The University of Sydney, Sydney, Australia
    PLoS ONE 6:e19203. 2011
  4. pmc Resveratrol, by modulating RNA processing factor levels, can influence the alternative splicing of pre-mRNAs
    M Andrea Markus
    Basic and Clinical Genomics Laboratory, School of Medical Sciences and Bosch Institute, The University of Sydney, Sydney, Australia
    PLoS ONE 6:e28926. 2011
  5. doi request reprint Association analyses of insulin signaling pathway gene polymorphisms with healthy aging and longevity in Americans of Japanese ancestry
    Brian J Morris
    DSc Honolulu Heart Program HHP Honolulu Asia Aging Study HAAS, Kuakini Medical Center, 347 North Kuakini Street, HPM 9, Honolulu, Hawaii 96817
    J Gerontol A Biol Sci Med Sci 69:270-3. 2014
  6. pmc Recommendation by a law body to ban infant male circumcision has serious worldwide implications for pediatric practice and human rights
    Michael J Bates
    School of Medical Sciences and Bosch Institute, University of Sydney, Sydney, NSW 2006, Australia
    BMC Pediatr 13:136. 2013
  7. doi request reprint Circumcision and lifetime risk of urinary tract infection: a systematic review and meta-analysis
    Brian J Morris
    School of Medical Sciences and Bosch Institute, University of Sydney, New South Wales, Australia
    J Urol 189:2118-24. 2013
  8. doi request reprint Seven sirtuins for seven deadly diseases of aging
    Brian J Morris
    Basic and Clinical Genomics Laboratory, School of Medical Sciences and Bosch Institute, Building F13, University of Sydney, NSW 2006, Australia
    Free Radic Biol Med 56:133-71. 2013
  9. pmc Review: a critical evaluation of arguments opposing male circumcision for HIV prevention in developed countries
    Brian J Morris
    School of Medical Sciences and Bosch Institute, University of Sydney, NSW, Australia
    AIDS Care 24:1565-75. 2012
  10. pmc Should male circumcision be advocated for genital cancer prevention?
    Brian J Morris
    Molecular Medical Sciences, University of Sydney, Australia
    Asian Pac J Cancer Prev 13:4839-42. 2012

Collaborators

Detail Information

Publications51

  1. ncbi request reprint Circumcision rates in the United States: rising or falling? What effect might the new affirmative pediatric policy statement have?
    Brian J Morris
    School of Medical Sciences, University of Sydney, Sydney, NSW, Australia Electronic address
    Mayo Clin Proc 89:677-86. 2014
    ..Campaigns should prioritize population subgroups with lower circumcision prevalence and a higher burden of diseases that can be ameliorated by circumcision. ..
  2. pmc The Strong Protective Effect of Circumcision against Cancer of the Penis
    Brian J Morris
    School of Medical Sciences and Bosch Institute, Sydney Medical School, The University of Sydney, Sydney, NSW 2006, Australia
    Adv Urol 2011:812368. 2011
    ..Given that adverse consequences of medical male circumcision, especially when performed in infancy, are rare, this simple prophylactic procedure should be promoted...
  3. pmc Genes influencing circadian differences in blood pressure in hypertensive mice
    Francine Z Marques
    Basic and Clinical Genomics Laboratory, School of Medical Sciences and Bosch Institute, The University of Sydney, Sydney, Australia
    PLoS ONE 6:e19203. 2011
    ..The findings may assist in the elucidation of the mechanism for the morning surge in BP in essential hypertension...
  4. pmc Resveratrol, by modulating RNA processing factor levels, can influence the alternative splicing of pre-mRNAs
    M Andrea Markus
    Basic and Clinical Genomics Laboratory, School of Medical Sciences and Bosch Institute, The University of Sydney, Sydney, Australia
    PLoS ONE 6:e28926. 2011
    ..Our results suggest that resveratrol might be an attractive small molecule to treat diseases in which aberrant splicing has been implicated, and justify more extensive research on the effects of resveratrol on the splicing machinery...
  5. doi request reprint Association analyses of insulin signaling pathway gene polymorphisms with healthy aging and longevity in Americans of Japanese ancestry
    Brian J Morris
    DSc Honolulu Heart Program HHP Honolulu Asia Aging Study HAAS, Kuakini Medical Center, 347 North Kuakini Street, HPM 9, Honolulu, Hawaii 96817
    J Gerontol A Biol Sci Med Sci 69:270-3. 2014
    ..Two initial, marginal associations with longevity did not remain significant after correction for multiple comparisons, nor were they correlated with aging-related phenotypes. ..
  6. pmc Recommendation by a law body to ban infant male circumcision has serious worldwide implications for pediatric practice and human rights
    Michael J Bates
    School of Medical Sciences and Bosch Institute, University of Sydney, Sydney, NSW 2006, Australia
    BMC Pediatr 13:136. 2013
    ..The acceptance of this recommendation would create a precedent for legislation elsewhere in the world, thereby posing a threat to pediatric practice, parental responsibilities and freedoms, and public health...
  7. doi request reprint Circumcision and lifetime risk of urinary tract infection: a systematic review and meta-analysis
    Brian J Morris
    School of Medical Sciences and Bosch Institute, University of Sydney, New South Wales, Australia
    J Urol 189:2118-24. 2013
    ..Thus, any intervention that might prevent urinary tract infection would be expected to reduce suffering and medical costs...
  8. doi request reprint Seven sirtuins for seven deadly diseases of aging
    Brian J Morris
    Basic and Clinical Genomics Laboratory, School of Medical Sciences and Bosch Institute, Building F13, University of Sydney, NSW 2006, Australia
    Free Radic Biol Med 56:133-71. 2013
    ..Each sirtuin forms a key hub to the intracellular pathways affected...
  9. pmc Review: a critical evaluation of arguments opposing male circumcision for HIV prevention in developed countries
    Brian J Morris
    School of Medical Sciences and Bosch Institute, University of Sydney, NSW, Australia
    AIDS Care 24:1565-75. 2012
    ..The scientific evidence indicates that medical MC is safe and effective. Its favourable risk/benefit ratio and cost/benefit support the advantages of medical MC...
  10. pmc Should male circumcision be advocated for genital cancer prevention?
    Brian J Morris
    Molecular Medical Sciences, University of Sydney, Australia
    Asian Pac J Cancer Prev 13:4839-42. 2012
    ..Male circumcision can reduce cervical, penile and possibly prostate cancer. Promotion of both HPV vaccination and male circumcision will synergistically maximize genital cancer prevention...
  11. doi request reprint The 2010 Royal Australasian College of Physicians' policy statement 'Circumcision of infant males' is not evidence based
    B J Morris
    School of Medical Sciences and Bosch Institute, The University of Sydney, NSW, Australia
    Intern Med J 42:822-8. 2012
    ..In the interests of public health and individual well-being, an extensive, comprehensive, balanced review of the scientific literature and a risk-benefit analysis should be conducted to formulate policy...
  12. doi request reprint Biological basis for the protective effect conferred by male circumcision against HIV infection
    B J Morris
    Basic and Clinical Genomics Laboratory, School of Medical Sciences and Bosch Institute, University of Sydney, Sydney, NSW, Australia
    Int J STD AIDS 23:153-9. 2012
    ..Thus, by various means, the foreskin is the primary biological weak point that permits HIV infection during heterosexual intercourse. The biological findings could explain why male circumcision protects against HIV infection...
  13. pmc A 'snip' in time: what is the best age to circumcise?
    Brian J Morris
    School of Medical Sciences, University of Sydney, Sydney, NSW 2006, Australia
    BMC Pediatr 12:20. 2012
    ..This is an important issue for many parents, but also pediatricians, other doctors, policy makers, public health authorities, medical bodies, and males themselves...
  14. pmc Male circumcision for HIV prevention: current evidence and implementation in sub-Saharan Africa
    Richard G Wamai
    Department of African American Studies, Northeastern University, Boston, MA, USA
    J Int AIDS Soc 14:49. 2011
    ....
  15. ncbi request reprint No association with hypertension of CLCNKB and TNFRSF1B polymorphisms at a hypertension locus on chromosome 1p36
    Helen J L Speirs
    Basic and Clinical Genomics Laboratory, School of Medical Sciences and Institute for Biomedical Research, The University of Sydney, Australia
    J Hypertens 23:1491-6. 2005
    ..Here we performed association studies in a well-characterized cohort of hypertensives and normotensives whose blood pressure status matched that of both their parents...
  16. ncbi request reprint No association of angiotensin-converting enzyme 2 gene (ACE2) polymorphisms with essential hypertension
    Adam V Benjafield
    Basic Clinical Genomics Laboratory, School of Medical Sciences and Institute for Biomedical Research, The University of Sydney, Sydney, Australia
    Am J Hypertens 17:624-8. 2004
    ..96); intron 16 variant 0.20 versus 0.19 in female subjects (P =.72) and 0.17 versus 0.17 in male subjects (P =.95). Haplotype analysis was also negative. These data provide little support for ACE2 in genetic predisposition to HT...
  17. doi request reprint Global identification of the genes and pathways differentially expressed in hypothalamus in early and established neurogenic hypertension
    Francine Z Marques
    Basic and Clinical Genomics Laboratory, School of Medical Sciences and Bosch Institute, The University of Sydney, New South Wales, Australia
    Physiol Genomics 43:766-71. 2011
    ....
  18. doi request reprint ZRANB2 localizes to supraspliceosomes and influences the alternative splicing of multiple genes in the transcriptome
    Yee Hwa J Yang
    School of Mathematics and Statistics, The University of Sydney, Sydney, NSW, 2006, Australia
    Mol Biol Rep 40:5381-95. 2013
    ..Several of these have been implicated in tumor development. In conclusion ZRANB2 is part of the supraspliceosome and causes differential splicing of numerous primary transcripts, some of which might have a role in cancer. ..
  19. ncbi request reprint Renin enhancer is critical for control of renin gene expression and cardiovascular function
    David J Adams
    School of Medical Sciences and Bosch Institute, University of Sydney, Sydney, New South Wales 2006, Australia
    J Biol Chem 281:31753-61. 2006
    ..In conclusion, the renin enhancer is critical for renin gene expression and physiological sequelae, including response to alteration in salt intake. The REKO mouse may be useful as a low renin expression model...
  20. pmc XE7: a novel splicing factor that interacts with ASF/SF2 and ZNF265
    A Helena Mangs
    Basic and Clinical Genomics Laboratory, School of Medical Sciences and Bosch Institute, The University of Sydney, NSW 2006, Australia
    Nucleic Acids Res 34:4976-86. 2006
    ..We have thus shown that the spliceosomal component XE7 resembles an SR-related splicing protein, and can influence alternative splicing...
  21. doi request reprint Meta-analysis of genome-wide gene expression differences in onset and maintenance phases of genetic hypertension
    Francine Z Marques
    Basic and Clinical Genomics Laboratory, School of Medical Sciences and Bosch Institute, University of Sydney, Sydney, New South Wales, Australia
    Hypertension 56:319-24. 2010
    ..Our meta-analysis has revealed many new genes for which the expression is altered in hypertension, so pointing to novel potential causative, maintenance, and responsive mechanisms and pathways...
  22. ncbi request reprint Association of G-protein-coupled receptor kinase 4 haplotypes, but not HSD3B1 or PTP1B polymorphisms, with essential hypertension
    Helen J L Speirs
    Basic and Clinical Genomics Laboratory, School of Medical Sciences and Institute for Biomedical Research, The University of Sydney, Sydney, NSW 2006, Australia
    J Hypertens 22:931-6. 2004
    ..To perform association studies of polymorphisms of the potential candidate essential hypertension (HT) genes GRK4, PTP1B and HSD3B1...
  23. ncbi request reprint The effect of resveratrol on a cell model of human aging
    Maurizio Stefani
    Basic and Clinical Genomics Laboratory, School of Medical Sciences and Bosch Institute, The University of Sydney, Sydney, New South Wales 2006, Australia
    Ann N Y Acad Sci 1114:407-18. 2007
    ..Serum deprivation and high confluency caused nuclear translocation of the SIRT1-regulated transcription factor FOXO3a. Our data indicate resveratrol's actions might cause FOXO recruitment to the nucleus...
  24. ncbi request reprint WT1 interacts with the splicing protein RBM4 and regulates its ability to modulate alternative splicing in vivo
    M Andrea Markus
    Basic and Clinical Genomics Laboratory, School of Medical Sciences and Bosch Institute, Building F13, The University of Sydney, NSW 2006, Australia
    Exp Cell Res 312:3379-88. 2006
    ..We found that overexpressed WT1(+KTS) abrogated this effect of RBM4 on splice-site selection, whereas WT1(-KTS) did not. We conclude that the (+KTS) form of WT1 is able to inhibit the effect of RBM4 on alternative splicing...
  25. doi request reprint Gene expression profiling reveals renin mRNA overexpression in human hypertensive kidneys and a role for microRNAs
    Francine Z Marques
    Basic and Clinical Genomics Laboratory, School of Medical Sciences and Bosch Institute, Building F13, University of Sydney, Sydney, New South Wales 2006, Australia
    Hypertension 58:1093-8. 2011
    ..Renin, CD36, and other mRNAs, as well as miRNAs and associated pathways identified in the present study, provide novel insights into hypertension etiology...
  26. ncbi request reprint Overweight, but not hypertension, is associated with SAH polymorphisms in Caucasians with essential hypertension
    Adam V Benjafield
    Basic and Clinical Genomics Laboratory, School of Medical Science and Institute for Biomedical Research, The University of Sydney, Sydney, Australia
    Hypertens Res 26:591-5. 2003
    ..01-0.04), although these lost their statistical significance after correction for multiple comparisons. In conclusion, the present data offers support for variation in SAH having a role in predisposition to overweight in hypertensives...
  27. ncbi request reprint Renin enhancer is crucial for full response in Renin expression to an in vivo stimulus
    M Andrea Markus
    Basic and Clinical Genomics Laboratory, School of Medical Sciences and Bosch Institute, Building F13, University of Sydney, NSW 2006, Australia
    Hypertension 50:933-8. 2007
    ..In conclusion, the renin enhancer is critical for replenishment of renin stores and response in renin to a chronic in vivo stimulus...
  28. ncbi request reprint WNK4 intron 10 polymorphism is not associated with hypertension
    Helen J L Speirs
    Basic and Clinical Genomics Laboratory, School of Medical Sciences and Institute of Biomedical Research, University of Sydney, NSW, Australia
    Hypertension 43:766-8. 2004
    ..In conclusion, our study provides no support for an association of the intron 10 variant of WNK4 with essential hypertension in the Anglo-Australian population studied...
  29. ncbi request reprint Genome-wide scan for hypertension in Sydney Sibships: the GENIHUSS study
    Adam V Benjafield
    Basic and Clinical Genomics Laboratory, School of Medical Sciences and Institute for Biomedical Research, The University of Sydney, Sydney, Australia
    Am J Hypertens 18:828-32. 2005
    ..Our study adds to findings of HT loci emanating from genome scans...
  30. ncbi request reprint Shorter Men Live Longer: Association of Height with Longevity and FOXO3 Genotype in American Men of Japanese Ancestry
    Qimei He
    Honolulu Heart Program Honolulu Asia Aging Study, Physicians Office Tower, Kuakini Medical Center, Honolulu, Hawaii, United States of America Pacific Health Research and Education Institute of the Veterans Affairs Pacific Islands Health Care System, Honolulu, Hawaii Department of Geriatric Medicine, John A Burns School of Medicine, University of Hawaii, Honolulu, Hawaii, United States of America
    PLoS ONE 9:e94385. 2014
    ..To determine the relation between height, FOXO3 genotype and age of death in humans...
  31. ncbi request reprint RACP's policy statement on infant male circumcision is ill-conceived
    Brian J Morris
    School of Medical Sciences and Institute for Biomedical Research, University of Sydney, New South Wales
    Aust N Z J Public Health 30:16-22; discussion 22-5. 2006
    ..To conduct a critical peer-review of the 2004 Policy Statement on routine male circumcision produced by the Royal Australasian College of Physicians (RACP)...
  32. doi request reprint The molecular basis of longevity, and clinical implications
    Francine Z Marques
    Basic and Clinical Genomics Laboratory, School of Medical Sciences and Bosch Institute, Building F13, The University of Sydney, NSW 2006, Australia
    Maturitas 65:87-91. 2010
    ....
  33. pmc Resveratrol in prevention and treatment of common clinical conditions of aging
    M Andrea Markus
    School of Medical Sciences, Bosch Institute, The University of Sydney, Sydney, NSW, Australia
    Clin Interv Aging 3:331-9. 2008
    ....
  34. ncbi request reprint A forkhead in the road to longevity: the molecular basis of lifespan becomes clearer
    Brian J Morris
    Basic and Clinical Genomics Laboratory, School of Medical Sciences and Institute for Biomedical Research, Building F13, The University of Sydney, NSW 2006, Australia
    J Hypertens 23:1285-309. 2005
    ..The present review describes how recent experimental strategies have identified key genes and intracellular pathways that are responsible for ageing and longevity...
  35. ncbi request reprint Why circumcision is a biomedical imperative for the 21(st) century
    Brian J Morris
    School of Medical Sciences and Bosch Institute, Building F13, The University of Sydney, Sydney, New South Wales 2006, Australia
    Bioessays 29:1147-58. 2007
    ..Most women prefer the circumcised penis for appearance, hygiene and sex. Given the convincing epidemiological evidence and biological support, routine circumcision should be highly recommended by all health professionals...
  36. pmc The zinc fingers of the SR-like protein ZRANB2 are single-stranded RNA-binding domains that recognize 5' splice site-like sequences
    Fionna E Loughlin
    School of Molecular and Microbial Biosciences, University of Sydney, Sydney NSW 2006, Australia
    Proc Natl Acad Sci U S A 106:5581-6. 2009
    ..The ZnFs of ZRANB2 therefore define another class of RNA-binding domain, advancing our understanding of RNA recognition and emphasizing the versatility of ZnF domains in molecular recognition...
  37. doi request reprint Fluorescence activated cell sorting of transiently transfected As4.1 cells shows renin enhancer directs on/off switching of renin promoter in vitro
    Brian J Morris
    Basic and Clinical Genomics Laboratory, School of Medical Sciences and Bosch Institute, The University of Sydney, Sydney, New South Wales, Australia
    Clin Exp Pharmacol Physiol 35:367-71. 2008
    ..Limitations of these findings are discussed...
  38. ncbi request reprint Tumor necrosis factor receptor 2 mRNA in rat models of hypertension
    Ruby C Y Lin
    Basic and Clinical Genomics Laboratory, School of Medical Sciences and Institute for Biomedical Research, The University of Sydney, Sydney, NSW 2006, Australia
    Am J Hypertens 16:685-8. 2003
    ..The ACTH-induced HT was not affected by huTNFR:Fc coadministration. The findings thus offer no support for altered Tnfr2 expression in the rat models studied...
  39. pmc Dietary approaches that delay age-related diseases
    Arthur V Everitt
    Centre for Education and Research on Ageing and ANZAC Research Institute, University of Sydney, Concord Repatriation General Hospital, Concord, NSW, Australia
    Clin Interv Aging 1:11-31. 2006
    ..Furthermore, there are studies suggesting that nutrition in childhood and even in the fetus may influence the later development of aging diseases and lifespan...
  40. ncbi request reprint Essential hypertension: genes and dreams
    Brian J Morris
    Basic and Clinical Genomics Laboratory, School of Medical Sciences and Institute for Biomedical Research, The University of Sydney, Sydney, Australia
    Clin Chem Lab Med 41:834-44. 2003
    ..The dream, however, of using this information in clinical genetic testing could turn out to be a nightmare. Thus at present the hype surrounding genes for complex polygenic diseases like hypertension far exceeds the reality...
  41. ncbi request reprint Case number and the financial impact of circumcision in reducing prostate cancer
    Brian J Morris
    School of Medical Sciences and Bosch Institute, The University of Sydney, Sydney, New South Wales, Australia
    BJU Int 100:5-6. 2007
  42. doi request reprint Resveratrol: cellular actions of a potent natural chemical that confers a diversity of health benefits
    Francine Z Marques
    Basic and Clinical Genomics Laboratory, School of Medical Sciences and Bosch Institute, Building F13, The University of Sydney, Sydney, NSW 2006, Australia
    Int J Biochem Cell Biol 41:2125-8. 2009
    ..Resveratrol and the new compounds are the subject of clinical trials to determine their consumer safety and suitability for the prevention and treatment of most common diseases of aging...
  43. doi request reprint RBM4: a multifunctional RNA-binding protein
    M Andrea Markus
    Basic and Clinical Genomics Laboratory, School of Medical Sciences and Bosch Institute, Building F13, The University of Sydney, Sydney, NSW 2006, Australia
    Int J Biochem Cell Biol 41:740-3. 2009
    ..Here we review current information about the function of RBM4 and its localization within the cell. We then speculate about its possible relationship to disease...
  44. ncbi request reprint ZRANB2: structural and functional insights into a novel splicing protein
    A Helena Mangs
    Basic and Clinical Genomics Laboratory, School of Medical Sciences and Bosch Institute, Building F13, The University of Sydney, NSW 2006, Australia
    Int J Biochem Cell Biol 40:2353-7. 2008
    ..ZRANB2 is one of 20 genes up-regulated in grade III ovarian serous papillary carcinoma. Here, we review current knowledge surrounding ZRANB2...
  45. ncbi request reprint HADHB, HuR, and CP1 bind to the distal 3'-untranslated region of human renin mRNA and differentially modulate renin expression
    David J Adams
    Basic and Clinical Genomics Laboratory, School of Medical Sciences and Institute for Biomedical Research, The University of Sydney, New South Wales 2006, Australia
    J Biol Chem 278:44894-903. 2003
    ..cAMP-mediated increased REN mRNA stability may involve stimulation of HuR and CP1, whereas REN mRNA decay may involve thiolase-dependent pathways...
  46. ncbi request reprint Association of obesity, but not diabetes or hypertension, with glucocorticoid receptor N363S variant
    Ruby C Y Lin
    Department of Physiology, School of Medical Sciences and Institute for Biomedical Research, The University of Sydney, Sydney, Australia
    Obes Res 11:802-8. 2003
    ..To determine whether the N363S variant in the glucocorticoid receptor (encoded by nuclear receptor subfamily 3, group C, member 1: NR3C1) is associated with obesity, type 2 diabetes, or hypertension...
  47. pmc Hormesis as a pro-healthy aging intervention in human beings?
    Francine Z Marques
    Basic and Clinical Genomics Laboratory, School of Medical Sciences and Bosch Institute, The University of Sydney, NSW 2006, Australia
    Dose Response 8:28-33. 2009
    ..Moderate-intensity exercise, weight management and healthy diet ameliorate diseases of aging to increase lifespan and this could involve hormesis...
  48. ncbi request reprint Haplotype analysis of aldosterone synthase gene (CYP11B2) polymorphisms shows association with essential hypertension
    Natasha N Kumar
    Department of Physiology, School of Medical Sciences, and Institute for Biomedical Research, The University of Sydney, Sydney, Australia
    J Hypertens 21:1331-7. 2003
    ..We therefore investigated CYP11B2 polymorphisms T-344C, T4986C and A6547G for association with essential HT. This included haplotype analysis and measurement of plasma aldosterone levels...
  49. ncbi request reprint Lark is the splicing factor RBM4 and exhibits unique subnuclear localization properties
    M Andrea Markus
    Basic and Clinical Genomics Laboratory, School of Medical Sciences and Bosch Institute for Biomedical Research, The University of Sydney, Sydney, Australia
    DNA Cell Biol 25:457-64. 2006
    ..In conclusion, RBM4 and Lark are the same protein, are localized in speckles and nucleoli, but can redistribute to perinucleolar clusters, consistent with a novel subnuclear pathway...
  50. doi request reprint Commentary on resveratrol and hormesis: resveratrol--a hormetic marvel in waiting?
    Francine Z Marques
    Basic and Clinical Genomics Laboratory, School of Medical Sciences and Bosch Institute, Anderson Stuart Building, University of Sydney, Australia
    Hum Exp Toxicol 29:1026-8. 2010
    ....
  51. ncbi request reprint Cervical human papillomavirus screening by PCR: advantages of targeting the E6/E7 region
    Brian J Morris
    Basic and Clinical Genomics Laboratory, School of Medical Sciences and Institute for Biomedical Research, The University of Sydney, Sydney, Australia
    Clin Chem Lab Med 43:1171-7. 2005
    ..The choice of region used for PCR has implications for HPV screening strategies in the clinical diagnosis and management of cervical cancer...