Isamu Mori

Summary

Publications

  1. doi request reprint Herpes simplex virus US3 protein kinase regulates host responses and determines neurovirulence
    Isamu Mori
    Faculty of Health and Nutrition, Shubun University, Aichi 491 0938, Japan
    Microbiol Immunol 56:351-5. 2012
  2. doi request reprint Herpes simplex virus type 1 persists in the aged brain through hypothetical expression of accessory genes
    Isamu Mori
    Faculty of Health and Nutrition, Shubun University, Aichi, Japan
    J Neurovirol 16:203-7. 2010
  3. ncbi request reprint Lipopolysaccharide enhances interferon-gamma-induced nitric oxide (NO) production in murine vascular endothelial cells via augmentation of interferon regulatory factor-1 activation
    Naoki Koide
    Department of Microbiology and Immunology, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan
    J Endotoxin Res 13:167-75. 2007
  4. ncbi request reprint Herpes simplex virus US3 protein kinase regulates virus-induced apoptosis in olfactory and vomeronasal chemosensory neurons in vivo
    Isamu Mori
    Department of Microbiology and Immunology, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan
    Microbes Infect 8:1806-12. 2006
  5. doi request reprint Interleukin-10 inhibits tumor necrosis factor-alpha production in lipopolysaccharide-stimulated RAW 264.7 cells through reduced MyD88 expression
    Jargalsaikhan Dagvadorj
    Department of Microbiology and Immunology, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan
    Innate Immun 14:109-15. 2008
  6. ncbi request reprint Lethal endotoxic shock using alpha-galactosylceramide sensitization as a new experimental model of septic shock
    Hiroyasu Ito
    Department of Microbiology and Immunology, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan
    Lab Invest 86:254-61. 2006
  7. ncbi request reprint 5-Fluorouracil prevents lipopolysaccharide-induced nitric oxide production in RAW 264.7 macrophage cells by inhibiting Akt-dependent nuclear factor-kappaB activation
    Shamima Islam
    Department of Microbiology and Immunology, Aichi Medical University School of Medicine, Nagakute, Aichi, 480 1195, Japan
    Cancer Chemother Pharmacol 59:227-33. 2007
  8. ncbi request reprint Characterization of biological activities of Brucella melitensis lipopolysaccharide
    Gantsetseg Tumurkhuu
    Department of Microbiology and Immunology, Aichi Medical University School of Medicine, Aichi, Japan
    Microbiol Immunol 50:421-7. 2006
  9. ncbi request reprint MnTBAP, a synthetic metalloporphyrin, inhibits production of tumor necrosis factor-alpha in lipopolysaccharide-stimulated RAW 264.7 macrophages cells via inhibiting oxidative stress-mediating p38 and SAPK/JNK signaling
    Gantsetseg Tumurkhuu
    Department of Microbiology and Immunology, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan
    FEMS Immunol Med Microbiol 49:304-11. 2007
  10. ncbi request reprint Defective responsiveness of CD5+ B1 cells to lipopolysaccharide in cytokine production
    Naoki Koide
    Department of Microbiology and Immunology, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan
    J Endotoxin Res 12:346-51. 2006

Collaborators

Detail Information

Publications16

  1. doi request reprint Herpes simplex virus US3 protein kinase regulates host responses and determines neurovirulence
    Isamu Mori
    Faculty of Health and Nutrition, Shubun University, Aichi 491 0938, Japan
    Microbiol Immunol 56:351-5. 2012
    ..In the present article, functions of the HSV US3 protein kinase are briefly reviewed, with special attention given to its role in regulating host responses and neurovirulence...
  2. doi request reprint Herpes simplex virus type 1 persists in the aged brain through hypothetical expression of accessory genes
    Isamu Mori
    Faculty of Health and Nutrition, Shubun University, Aichi, Japan
    J Neurovirol 16:203-7. 2010
    ..This mini-review focuses on these viral accessory genes that may shed light on the potential mechanisms of this enigmatic phenomenon in the elderly brain...
  3. ncbi request reprint Lipopolysaccharide enhances interferon-gamma-induced nitric oxide (NO) production in murine vascular endothelial cells via augmentation of interferon regulatory factor-1 activation
    Naoki Koide
    Department of Microbiology and Immunology, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan
    J Endotoxin Res 13:167-75. 2007
    ..Therefore, it is proposed that LPS enhanced NO production in IFN-gamma-stimulated END-D cells via augmenting p38 MAPKmediated IRF-1 activation...
  4. ncbi request reprint Herpes simplex virus US3 protein kinase regulates virus-induced apoptosis in olfactory and vomeronasal chemosensory neurons in vivo
    Isamu Mori
    Department of Microbiology and Immunology, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan
    Microbes Infect 8:1806-12. 2006
    ..Furthermore, virus-induced neuronal apoptosis of peripheral nervous system cells may be a protective host response that blocks viral transmission to the CNS...
  5. doi request reprint Interleukin-10 inhibits tumor necrosis factor-alpha production in lipopolysaccharide-stimulated RAW 264.7 cells through reduced MyD88 expression
    Jargalsaikhan Dagvadorj
    Department of Microbiology and Immunology, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan
    Innate Immun 14:109-15. 2008
    ..Therefore, IL-10 was suggested to inhibit LPS-induced TNF-alpha production via reduced MyD88 expression...
  6. ncbi request reprint Lethal endotoxic shock using alpha-galactosylceramide sensitization as a new experimental model of septic shock
    Hiroyasu Ito
    Department of Microbiology and Immunology, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan
    Lab Invest 86:254-61. 2006
    ..The LPS-mediated lethal shock using alpha-GalCer sensitization might be useful for researchers employing experimental models of sepsis and septic shock...
  7. ncbi request reprint 5-Fluorouracil prevents lipopolysaccharide-induced nitric oxide production in RAW 264.7 macrophage cells by inhibiting Akt-dependent nuclear factor-kappaB activation
    Shamima Islam
    Department of Microbiology and Immunology, Aichi Medical University School of Medicine, Nagakute, Aichi, 480 1195, Japan
    Cancer Chemother Pharmacol 59:227-33. 2007
    ..5-FU did not affect a series of mitogen-activated protein kinases. Therefore, 5-FU was suggested to inhibit the LPS-induced NO production in activated macrophages through preventing Akt-dependent NF-kappaB activation...
  8. ncbi request reprint Characterization of biological activities of Brucella melitensis lipopolysaccharide
    Gantsetseg Tumurkhuu
    Department of Microbiology and Immunology, Aichi Medical University School of Medicine, Aichi, Japan
    Microbiol Immunol 50:421-7. 2006
    ..coli LPS. B. melitensis LPS as well as E. coli LPS exhibited a strong adjuvant action on antibody response to bovine serum. The characteristic biological activities of B. melitensis are discussed...
  9. ncbi request reprint MnTBAP, a synthetic metalloporphyrin, inhibits production of tumor necrosis factor-alpha in lipopolysaccharide-stimulated RAW 264.7 macrophages cells via inhibiting oxidative stress-mediating p38 and SAPK/JNK signaling
    Gantsetseg Tumurkhuu
    Department of Microbiology and Immunology, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan
    FEMS Immunol Med Microbiol 49:304-11. 2007
    ..MnTBAP was suggested to inhibit lipopolysaccharide-induced TNF-alpha production by the prevention of intracellular ROS generation and subsequent inactivation of p38 MAPK and SAPK/JNK...
  10. ncbi request reprint Defective responsiveness of CD5+ B1 cells to lipopolysaccharide in cytokine production
    Naoki Koide
    Department of Microbiology and Immunology, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan
    J Endotoxin Res 12:346-51. 2006
    ..Defective responsiveness of TH2.52 B1 cells to LPS in cytokine production might be responsible for the failure of IFN-beta production due to the lack of molecules participating in the MyD88-independent pathway...
  11. ncbi request reprint Augmentation of lipopolysaccharide-induced nitric oxide production by alpha-galactosylceramide in mouse peritoneal cells
    Hiroyasu Ito
    Department of Microbiology and Immunology, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan
    J Endotoxin Res 11:213-9. 2005
    ..Therefore, it was suggested that alpha-GalCer might augment LPS-induced NO production in peritoneal cells through release of IFN-gamma from NKT cells...
  12. doi request reprint Oncolytic virotherapy for malignant melanoma with herpes simplex virus type 1 mutant HF10
    Daisuke Watanabe
    Department of Dermatology, Aichi Medical University, Nagakute, Aichi, Japan
    J Dermatol Sci 50:185-96. 2008
    ..Many viruses have been engineered and evaluated for their potential as therapeutic agents in the treatment of malignant neoplasm, including malignant melanoma...
  13. ncbi request reprint Olfactory transmission of neurotropic viruses
    Isamu Mori
    Department of Microbiology and Immunology, Research Center for Infectious Disease, Aichi Medical University School of Medecine, Aichi, Japan
    J Neurovirol 11:129-37. 2005
    ..Here the authors review the olfactory transmission of infectious agents and the resulting hazards to human and animal health...
  14. ncbi request reprint Chlamydia pneumoniae infection enhances lectin-like oxidized low-density lipoprotein receptor (LOX-1) expression on human endothelial cells
    Tomoaki Yoshida
    Department of Microbiology and Immunology, Aichi Medical University, School of Medicine, Nagakute, Aichi, Japan
    FEMS Microbiol Lett 260:17-22. 2006
    ..Among the scavenger receptors analyzed, LOX-1 transcription, which prefers oxidized LDL to acetylated LDL, was significantly amplified...
  15. ncbi request reprint Reactivation of HSV-1 in the brain of patients with familial Alzheimer's disease
    Isamu Mori
    Department of Microbiology and Immunology, Aichi Medical University School of Medicine, Aichi, Japan
    J Med Virol 73:605-11. 2004
    ....
  16. ncbi request reprint Piceatannol prevents lipopolysaccharide (LPS)-induced nitric oxide (NO) production and nuclear factor (NF)-kappaB activation by inhibiting IkappaB kinase (IKK)
    Shamima Islam
    Department of Microbiology and Immunology and Research Center for Infectious Disease, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan
    Microbiol Immunol 48:729-36. 2004
    ..The detailed mechanism of the inhibition of LPS-induced NO production by piceatannol is discussed...