The evolving role of oral insulin in the treatment of diabetes using a novel RapidMist SystemPankaj Modi
VP Research and Development, Generex Biotechnology Corporation, Toronto, Ontario, Canada
Diabetes Metab Res Rev 18:S38-42. 2002
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- Diabetes beyond insulin: review of new drugs for treatment of diabetes mellitus
Pankaj Modi
Innovatech Rx, 519 Golf Links Road, Ancaster, Ontario L9G4X6, Canada
Curr Drug Discov Technol 4:39-47. 2007
..These agents have distinct characteristics that help in their selection for the treatment of type 1 and type 2 diabetes...
- Metabolic syndrome--risk factors for atherosclerosis and diabetes
Marko Mihic
Diabetes Care and Research Clinic, St Joseph Hospital, University of Toronto, Toronto, Canada
Curr Diabetes Rev 4:122-8. 2008
..To evaluate the lipoprotein profiles, triglycerides and glycemia along with the abdominal fat to explore the risk factors associated with non-diabetic state to IGF, IGT and Type-2 diabetes in Canadian population...
- Future therapeutic directions; new medications and insulin delivery in a changing world for effective diabetes management
Pankaj Modi
Innovatech Corporation, 519 Golf Links Road, Ancaster, ON, L9G 4X6, Canada
Curr Drug Discov Technol 6:200-13. 2009
..This review discusses how these approaches can help patients manage their diabetes effectively by considering new insulin formulations and delivery devices and newer therapeutics...
- Comparison of pharmacokinetic and pharmacodynamic properties of single-dose oral insulin spray and subcutaneous insulin injection in healthy subjects using the euglycemic clamp technique
Simona Cernea
Diabetes Unit, Department of Internal Medicine, Hadassah-Hebrew University Hospital, PO Box 12000, Jerusalem 91120, Israel
Clin Ther 26:2084-91. 2004
..The short T(max) and the 120-minute duration of effect of oral insulin spray suggest it may be a promising alternative for fulfilling meal-related insulin requirements in persons with diabetes...
- Oral spray insulin in treatment of type 2 diabetes: a comparison of efficacy of the oral spray insulin (Oralin) with subcutaneous (SC) insulin injection, a proof of concept study
Jaime Guevara-Aguirre
Institute of Endocrinology IEMIR, Quito, Ecuador
Diabetes Metab Res Rev 20:472-8. 2004
..001). CONCLUSIONS: This proof-of-concept study results demonstrated that Oralin could be used as meal insulin in place of mealtime-insulin injections in subjects with type 2 diabetes to regulate the postprandial glucose levels...
- Beneficial effects of addition of oral spray insulin (Oralin) on insulin secretion and metabolic control in subjects with type 2 diabetes mellitus suboptimally controlled on oral hypoglycemic agents
Jaime Guevara-Aguirre
Institute of Endocrinology IEMIR, Quito, Ecuador
Diabetes Technol Ther 6:1-8. 2004
..This study results demonstrated that Oralin could be used as meal insulin as an add-on therapy in combination with failing OHAs treatment in subjects with type 2 diabetes to regulate postprandial glucose levels...
- Dose-response relationship of oral insulin spray in healthy subjects
Simona Cernea
Diabetes Unit, Dept of Medicine, Hadassah Hospital, POB 12000, Jerusalem, Israel 91120
Diabetes Care 28:1353-7. 2005
..A dose-response relationship in the absorption and metabolic effect of the oral insulin was noted...
Cefoperazone-sulbactam for treatment of intra-abdominal infections: results from a randomized, parallel group study in IndiaAbhijit Chandra
King George Medical University, Lucknow, India
Surg Infect (Larchmt) 9:367-76. 2008
..Simpler regimens that preserve an adequate spectrum of coverage, but allow easier administration and have fewer side effects, may be a more desirable option...
- Biokinetics of buccal spray insulin in patients with type 1 diabetes
Paolo Pozzilli
Department of Endocrinoplogy and Diabetes, University Campus Bio Medico, Rome, Italy
Metabolism 54:930-4. 2005
..To evaluate the metabolic effect of buccal spray insulin compared with subcutaneous regular insulin in patients with type 1 diabetes...
