Rama Devi Mittal
Mittal R, Mandal R, Gangwar R. Base excision repair pathway genes polymorphism in prostate and bladder cancer risk in North Indian population. Mech Ageing Dev. 2012;133:127-32 pubmed publisher
..However APE1 GG genotype conferred a protective association with BC susceptibility. Larger studies and the more SNPs in the same pathway are needed to verify these findings. ..
Mittal R, Mandal R, Singh A, Srivastava P. Death receptor 4 variants enhanced prostate cancer risk in North Indian population. Tumour Biol. 2015;36:5655-61 pubmed publisher
..Our observations suggested that genetic variants of the DR4 gene significantly influence the risk of PCa in North Indian population and might be involved in the etiology of PCa. ..
Mittal R, Gangwar R, George G, Mittal T, Kapoor R. Investigative role of pre-microRNAs in bladder cancer patients: a case-control study in North India. DNA Cell Biol. 2011;30:401-6 pubmed publisher
..This could further provide new prospects for understanding the underlying mechanisms between miRNAs and disease etiology. ..
Mittal R, Gangwar R, Mandal R, Srivastava P, Ahirwar D. Gene variants of XRCC4 and XRCC3 and their association with risk for urothelial bladder cancer. Mol Biol Rep. 2012;39:1667-75 pubmed publisher
..Our results suggested that the XRCC4 intron 3 rs6869366 genotype and intron 7 rs28360317 may be associated with UBC risk and may be a novel useful marker for primary prevention and anticancer intervention. ..
Mittal R, Mittal T, Singh A, Mandal R. Association of caspases with an increased prostate cancer risk in north Indian population. DNA Cell Biol. 2012;31:67-73 pubmed publisher
..Our observations suggested positive association of caspase-3 and diplotype analysis of caspase-5 to be associated with PCa risk. Interaction of caspase-3 and -5 genotypes also modulated the PCa risk. ..
Mittal R, Srivastava P, Mittal T, Verma A, Jaiswal P, Singh V, et al
. Association of death receptor 4, Caspase 3 and 5 gene polymorphism with increased risk to bladder cancer in North Indians. Eur J Surg Oncol. 2011;37:727-33 pubmed publisher
..009; HR = 5.20). This study provided new support for the association of DR4 and Casp3, 5 in BC development, the tumorigenic effect of which was observed to be more enhanced in case of smoking exposure. ..
Singh V, Jaiswal P, Mittal R. Replicative study of GWAS TP63C/T, TERTC/T, and SLC14A1C/T with susceptibility to bladder cancer in North Indians. Urol Oncol. 2014;32:1209-14 pubmed publisher
..However, TP63C/T showed reduced risk of BC susceptibility. More replicate studies with large sample size and diverse ethnicity are required to validate these observations. ..