BENOIT MIOTTO

Summary

Affiliation: CNRS
Location: Paris, France
URL: http://fdeg.parisepigenetics.com/group-members/article/benoit-miotto

Publications

  1. ncbi JNK1 phosphorylation of Cdt1 inhibits recruitment of HBO1 histone acetylase and blocks replication licensing in response to stress
    Benoit Miotto
    Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA
    Mol Cell 44:62-71. 2011
  2. ncbi Regulation of DNA licensing by targeted chromatin remodeling
    Benoit Miotto
    Université Denis Diderot Paris 7 Paris, France
    Cell Cycle 10:1522. 2011
  3. ncbi [Histone H4 lysine 16 acetylation: from genome regulation to tumoral progression]
    Benoit Miotto
    Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA
    Med Sci (Paris) 23:735-40. 2007
  4. ncbi HBO1 histone acetylase is a coactivator of the replication licensing factor Cdt1
    Benoit Miotto
    Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, USA
    Genes Dev 22:2633-8. 2008
  5. ncbi Mammalian methyl-binding proteins: what might they do?
    Michael Joulie
    CNRS UMR7216, Universite Paris Diderot, Paris, France
    Bioessays 32:1025-32. 2010
  6. ncbi Control of DNA replication: a new facet of Hox proteins?
    Benoit Miotto
    UMR7216 Epigénétique et Destin Cellulaire, CNRS, Universite Paris 7, Paris, France
    Bioessays 32:800-7. 2010
  7. ncbi HBO1 histone acetylase activity is essential for DNA replication licensing and inhibited by Geminin
    Benoit Miotto
    Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA
    Mol Cell 37:57-66. 2010
  8. ncbi Differential gene regulation by selective association of transcriptional coactivators and bZIP DNA-binding domains
    Benoit Miotto
    Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA
    Mol Cell Biol 26:5969-82. 2006
  9. ncbi Chameau HAT and DRpd3 HDAC function as antagonistic cofactors of JNK/AP-1-dependent transcription during Drosophila metamorphosis
    Benoit Miotto
    Laboratoire de Genetique et Physiologie du Developpement, Institut de Biologie du Developpement de Marseille, CNRS Inserm Université de la Méditerranée, Parc Scientifique de Luminy, 13288 Marseille Cedex 9, France
    Genes Dev 20:101-12. 2006
  10. ncbi The MYST domain acetyltransferase Chameau functions in epigenetic mechanisms of transcriptional repression
    Aurelie Grienenberger
    Laboratoire de Genetique et Physiologie du Developpement, Institut de Biologie du Developpement de Marseille, CNRS Inserm Université de la Méditerranée, Parc Scientifique de Luminy, Case 907, 13288 Marseille Cedex 9, France
    Curr Biol 12:762-6. 2002

Detail Information

Publications11

  1. ncbi JNK1 phosphorylation of Cdt1 inhibits recruitment of HBO1 histone acetylase and blocks replication licensing in response to stress
    Benoit Miotto
    Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA
    Mol Cell 44:62-71. 2011
    ....
  2. ncbi Regulation of DNA licensing by targeted chromatin remodeling
    Benoit Miotto
    Université Denis Diderot Paris 7 Paris, France
    Cell Cycle 10:1522. 2011
    ..Comment on: Wong P.G., et al. Cell Cycle 2010; 9:4351-63...
  3. ncbi [Histone H4 lysine 16 acetylation: from genome regulation to tumoral progression]
    Benoit Miotto
    Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA
    Med Sci (Paris) 23:735-40. 2007
    ..Recent discoveries highlight its crucial involvement in events such as transcription regulation, chromatin specialization, chromosome compaction and tumoral progression...
  4. ncbi HBO1 histone acetylase is a coactivator of the replication licensing factor Cdt1
    Benoit Miotto
    Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, USA
    Genes Dev 22:2633-8. 2008
    ..As HBO1 is also a transcriptional coactivator, it has the potential to integrate internal and external stimuli to coordinate transcriptional responses with initiation of DNA replication...
  5. ncbi Mammalian methyl-binding proteins: what might they do?
    Michael Joulie
    CNRS UMR7216, Universite Paris Diderot, Paris, France
    Bioessays 32:1025-32. 2010
    ..Here we discuss the following issues: what are other possible roles for the known MBPs? Why are these proteins not essential in mammals? Are there other MBPs left to discover? Could CpG methylation be nonessential?..
  6. ncbi Control of DNA replication: a new facet of Hox proteins?
    Benoit Miotto
    UMR7216 Epigénétique et Destin Cellulaire, CNRS, Universite Paris 7, Paris, France
    Bioessays 32:800-7. 2010
    ..In this review we summarize the available data linking Hox proteins to the replication machinery and discuss the developmental and pathological implications of this new facet of Hox protein function...
  7. ncbi HBO1 histone acetylase activity is essential for DNA replication licensing and inhibited by Geminin
    Benoit Miotto
    Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA
    Mol Cell 37:57-66. 2010
    ..Thus, H4 acetylation at origins by HBO1 is critical for replication licensing by Cdt1, and negative regulation of licensing by Geminin is likely to involve inhibition of HBO1 histone acetylase activity...
  8. ncbi Differential gene regulation by selective association of transcriptional coactivators and bZIP DNA-binding domains
    Benoit Miotto
    Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA
    Mol Cell Biol 26:5969-82. 2006
    ..Thus, the bZIP domain mediates selective interactions with coactivators and hence differential regulation of gene expression...
  9. ncbi Chameau HAT and DRpd3 HDAC function as antagonistic cofactors of JNK/AP-1-dependent transcription during Drosophila metamorphosis
    Benoit Miotto
    Laboratoire de Genetique et Physiologie du Developpement, Institut de Biologie du Developpement de Marseille, CNRS Inserm Université de la Méditerranée, Parc Scientifique de Luminy, 13288 Marseille Cedex 9, France
    Genes Dev 20:101-12. 2006
    ..This study establishes a direct link among JNK signaling, DFos phosphorylation, chromatin modification, and AP-1-dependent transcription and its importance in a developing organism...
  10. ncbi The MYST domain acetyltransferase Chameau functions in epigenetic mechanisms of transcriptional repression
    Aurelie Grienenberger
    Laboratoire de Genetique et Physiologie du Developpement, Institut de Biologie du Developpement de Marseille, CNRS Inserm Université de la Méditerranée, Parc Scientifique de Luminy, Case 907, 13288 Marseille Cedex 9, France
    Curr Biol 12:762-6. 2002
    ....