Sang Hyun Min

Summary

Publications

  1. Chae U, Lee H, Kim B, Jung H, Kim B, Lee A, et al. A negative feedback loop between XBP1 and Fbw7 regulates cancer development. Oncogenesis. 2019;8:12 pubmed publisher
    ..Therefore, a negative feedback loop between Fbw7 and XBP1 contributes to the regulation of tumor development and can be an attractive target for novel therapy in cancers. ..
  2. Ahn S, Chen Z, Lee J, Lee S, Min S, Kim N, et al. Inhibitory Effects of 2N1HIA (2-(3-(2-Fluoro-4-Methoxyphenyl)-6-Oxo-1(6H)-Pyridazinyl)-N-1H-Indol-5-Ylacetamide) on Osteoclast Differentiation via Suppressing Cathepsin K Expression. Molecules. 2018;23: pubmed publisher
  3. Cho E, Lee J, Lee J, Chen Z, Ahn S, Kim N, et al. BCPA {N,N'-1,4-Butanediylbis[3-(2-chlorophenyl)acrylamide]} Inhibits Osteoclast Differentiation through Increased Retention of Peptidyl-Prolyl cis-trans Isomerase Never in Mitosis A-Interacting 1. Int J Mol Sci. 2018;19: pubmed publisher
    ..These data suggest that BCPA can inhibit osteoclastogenesis by regulating the expression of the DC-STAMP osteoclast fusion protein by attenuating Pin1 reduction. Therefore, BCPA may be used to treat osteoporosis. ..
  4. Han H, Hahn S, Jeong H, Jee J, Nam M, Kim H, et al. LINCS L1000 dataset-based repositioning of CGP-60474 as a highly potent anti-endotoxemic agent. Sci Rep. 2018;8:14969 pubmed publisher
    ..Additionally, the virtual screening strategy using the LINCS L1000 perturbation dataset could be a cost and time effective tool in the early stages of drug development. ..
  5. Min S, Zhou X, Lu K. The role of Pin1 in the development and treatment of cancer. Arch Pharm Res. 2016;39:1609-1620 pubmed publisher
    ..This review will describe the role of Pin1 in cancer and the current status of Pin1 inhibitor development. ..