Edward J Mills

Summary

Publications

  1. ncbi request reprint Simple, effective interventions are key to improving adherence in marginalized populations
    Edward J Mills
    Clin Infect Dis 45:916-7. 2007
  2. ncbi request reprint Should active recruitment of health workers from sub-Saharan Africa be viewed as a crime?
    Edward J Mills
    British Columbia Centre for Excellence in HIV AIDS, University of British Columbia, Canada
    Lancet 371:685-8. 2008
  3. ncbi request reprint The impact of conflict on HIV/AIDS in sub-Saharan Africa
    Edward J Mills
    Centre for International Health and Human Rights Studies, Toronto, Canada
    Int J STD AIDS 17:713-7. 2006
  4. ncbi request reprint Adherence to antiretroviral therapy in sub-Saharan Africa and North America: a meta-analysis
    Edward J Mills
    Centre for International Health and Human Rights Studies, Toronto, Ontario, Canada
    JAMA 296:679-90. 2006
  5. ncbi request reprint Randomized trials stopped early for harm in HIV/AIDS: a systematic survey
    Edward Mills
    Centre for International Health and Human Rights Studies, North York, Ontario, Canada
    HIV Clin Trials 7:24-33. 2006
  6. doi request reprint Male sex and the risk of mortality among individuals enrolled in antiretroviral therapy programs in Africa: a systematic review and meta-analysis
    Eric Druyts
    Faculty of Health Sciences, University of Ottawa, Ottawa, Ontario, Canada
    AIDS 27:417-25. 2013
  7. pmc Adherence to HAART: a systematic review of developed and developing nation patient-reported barriers and facilitators
    Edward J Mills
    Centre for International Health and Human Rights Studies, Toronto, Ontario, Canada
    PLoS Med 3:e438. 2006
  8. pmc Naturopathic care for chronic low back pain: a randomized trial
    Orest Szczurko
    Division of Clinical Epidemiology, Canadian College of Naturopathic Medicine, Toronto, Ontario, Canada
    PLoS ONE 2:e919. 2007
  9. pmc Naturopathic care for anxiety: a randomized controlled trial ISRCTN78958974
    Kieran Cooley
    Department of Research and Clinical Epidemiology, The Canadian College of Naturopathic Medicine, Toronto, Canada
    PLoS ONE 4:e6628. 2009
  10. doi request reprint Long-term health care interruptions among HIV-positive patients in Uganda
    Edward J Mills
    University of Ottawa, Ottawa, Ontario, Canada
    J Acquir Immune Defic Syndr 63:e23-7. 2013

Collaborators

Detail Information

Publications47

  1. ncbi request reprint Simple, effective interventions are key to improving adherence in marginalized populations
    Edward J Mills
    Clin Infect Dis 45:916-7. 2007
  2. ncbi request reprint Should active recruitment of health workers from sub-Saharan Africa be viewed as a crime?
    Edward J Mills
    British Columbia Centre for Excellence in HIV AIDS, University of British Columbia, Canada
    Lancet 371:685-8. 2008
  3. ncbi request reprint The impact of conflict on HIV/AIDS in sub-Saharan Africa
    Edward J Mills
    Centre for International Health and Human Rights Studies, Toronto, Canada
    Int J STD AIDS 17:713-7. 2006
    ..We examine the complexity of monitoring HIV/AIDS in conflict settings. We argue that increased efforts are needed to protect vulnerable populations and design health-delivery systems that are sustainable in settings of conflict...
  4. ncbi request reprint Adherence to antiretroviral therapy in sub-Saharan Africa and North America: a meta-analysis
    Edward J Mills
    Centre for International Health and Human Rights Studies, Toronto, Ontario, Canada
    JAMA 296:679-90. 2006
    ..Concerns about incomplete adherence among patients living in poverty have been an important consideration in expanding the access to antiretroviral therapy in sub-Saharan Africa...
  5. ncbi request reprint Randomized trials stopped early for harm in HIV/AIDS: a systematic survey
    Edward Mills
    Centre for International Health and Human Rights Studies, North York, Ontario, Canada
    HIV Clin Trials 7:24-33. 2006
    ..We assessed the prevalence of randomized clinical trials (RCTs) stopped early for harm in HIV/AIDS and determined the quality of reporting of methods to inform the decision to stop the trial...
  6. doi request reprint Male sex and the risk of mortality among individuals enrolled in antiretroviral therapy programs in Africa: a systematic review and meta-analysis
    Eric Druyts
    Faculty of Health Sciences, University of Ottawa, Ottawa, Ontario, Canada
    AIDS 27:417-25. 2013
    ..HIV/AIDS has historically had a sex and gender-focused approach to prevention and care. Some evidence suggests that HIV-positive men have worse treatment outcomes than their women counterparts in Africa...
  7. pmc Adherence to HAART: a systematic review of developed and developing nation patient-reported barriers and facilitators
    Edward J Mills
    Centre for International Health and Human Rights Studies, Toronto, Ontario, Canada
    PLoS Med 3:e438. 2006
    ..We systematically reviewed the literature to determine patient-reported barriers and facilitators to adhering to antiretroviral therapy...
  8. pmc Naturopathic care for chronic low back pain: a randomized trial
    Orest Szczurko
    Division of Clinical Epidemiology, Canadian College of Naturopathic Medicine, Toronto, Ontario, Canada
    PLoS ONE 2:e919. 2007
    ..Chronic low back pain represents a substantial cost to employers through benefits coverage and days missed due to incapacity. We sought to explore the effectiveness of Naturopathic care on chronic low back pain...
  9. pmc Naturopathic care for anxiety: a randomized controlled trial ISRCTN78958974
    Kieran Cooley
    Department of Research and Clinical Epidemiology, The Canadian College of Naturopathic Medicine, Toronto, Canada
    PLoS ONE 4:e6628. 2009
    ..This study sought to explore the effectiveness of naturopathic care on anxiety symptoms using a randomized trial...
  10. doi request reprint Long-term health care interruptions among HIV-positive patients in Uganda
    Edward J Mills
    University of Ottawa, Ottawa, Ontario, Canada
    J Acquir Immune Defic Syndr 63:e23-7. 2013
    ..We examined risk factors for health care interruptions and loss to follow-up within a cohort receiving ART in Uganda...
  11. doi request reprint Life expectancy of persons receiving combination antiretroviral therapy in low-income countries: a cohort analysis from Uganda
    Edward J Mills
    University of Ottawa, Ottawa, Ontario, Canada
    Ann Intern Med 155:209-16. 2011
    ..Little is known about the effect of combination antiretroviral therapy (cART) on life expectancy in sub-Saharan Africa...
  12. doi request reprint Micronutrient Deficiency and Treatment Adherence in a Randomized Controlled Trial of Micronutrient Supplementation in ART-Naïve Persons with HIV
    Louise Balfour
    CIHR Canadian HIV Trials Network CTN, Vancouver, British Columbia, Canada Division of Infectious Diseases, Department of Medicine, University of Ottawa at The Ottawa Hospital, Ottawa, Ontario, Canada
    PLoS ONE 9:e85607. 2014
    ..The MAINTAIN study is an on-going RCT comparing high-dose micronutrient and anti-oxidant supplementation versus recommended daily allowance (RDA) vitamins in slowing HIV immune deficiency progression in ART-naïve people with HIV infection...
  13. doi request reprint Why the findings of published multiple treatment comparison meta-analyses of biologic treatments for rheumatoid arthritis are different: an overview of recurrent methodological shortcomings
    Kristian Thorlund
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    Ann Rheum Dis 72:1524-35. 2013
    ....
  14. doi request reprint Primary prevention of cardiovascular mortality and events with statin treatments: a network meta-analysis involving more than 65,000 patients
    Edward J Mills
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    J Am Coll Cardiol 52:1769-81. 2008
    ..This study aimed to evaluate the effectiveness of 3-hydroxy-3-methyl-glutaryl-CoA reductase inhibitors (statins) in primary prevention of cardiovascular events...
  15. doi request reprint A users' guide to understanding therapeutic substitutions
    Edward J Mills
    Faculty of Health Sciences, University of Ottawa, 43 Templeton Street, Ottawa, Canada K1N6X1 Centre for Clinical Epidemiology and Evaluation C2E2, University of British Columbia, 828 West 10th Ave, Research Pavilion, Vancouver, Canada, V5Z 1M9 Electronic address
    J Clin Epidemiol 67:305-13. 2014
    ..This article uses a problem-based format to address the biological mechanism, validity, and results of a scenario in which therapeutic substitutions may be considered...
  16. doi request reprint Design and methods of the MAINTAIN study: a randomized controlled clinical trial of micronutrient and antioxidant supplementation in untreated HIV infection
    Neera Singhal
    Department of Medicine, University of Ottawa at Ottawa Hospital Research Institute, Ottawa, Ontario, Canada
    Contemp Clin Trials 31:604-11. 2010
    ..We discuss here the study design and methods, often used for evaluation of complementary and adjunctive treatments for health maintenance in HIV infection, which are common interventions...
  17. doi request reprint Low-dose aspirin and cancer mortality: a meta-analysis of randomized trials
    Edward J Mills
    Faculty of Health Sciences, University of Ottawa, Ontario, Canada
    Am J Med 125:560-7. 2012
    ..We aimed to determine whether cancer mortality also is reduced by low-dose aspirin in the shorter term...
  18. ncbi request reprint Epidemiology and reporting of randomized trials employing re-randomization of patient groups: a systematic survey
    Edward J Mills
    Department of Clinical Epidemiology and Biostatistics, McMaster University, 1200 Main Street West, Hamilton, Ontario, Canada
    Contemp Clin Trials 28:268-75. 2007
    ....
  19. ncbi request reprint The effects of green tea consumption on incidence of breast cancer and recurrence of breast cancer: a systematic review and meta-analysis
    Dugald Seely
    Department of Clinical Epidemiology, Canadian College of Naturopathic Medicine, Toronto, Ontario, Canada
    Integr Cancer Ther 4:144-55. 2005
    ..Green tea is widely used by women for the prevention and treatment of breast cancer. The authors aimed to determine the efficacy of green tea ingestion on the risk of breast cancer development and the risk of breast cancer recurrence...
  20. doi request reprint Stopping randomized trials early for benefit and estimation of treatment effects: systematic review and meta-regression analysis
    Dirk Bassler
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    JAMA 303:1180-7. 2010
    ..Theory and simulation suggest that randomized controlled trials (RCTs) stopped early for benefit (truncated RCTs) systematically overestimate treatment effects for the outcome that precipitated early stopping...
  21. ncbi request reprint A wake-up call for global access to salvage HIV drug regimens
    Edward J Mills
    British Columbia Centre for Excellence in HIV AIDS, Vancouver, BC, Canada
    Lancet 370:1885-7. 2007
  22. doi request reprint Risk of resistance to highly active antiretroviral therapy among HIV-positive injecting drug users: a meta-analysis
    Daniel Werb
    British Columbia Centre for Excellence in HIV AIDS, University of British Columbia, 608 1081 Burrard Street, Vancouver, BC, Canada
    Lancet Infect Dis 10:464-9. 2010
    ..Therapeutic guidelines should consider reassessment of this issue...
  23. doi request reprint The effectiveness of anti-illicit-drug public-service announcements: a systematic review and meta-analysis
    Dan Werb
    British Columbia Centre for Excellence in HIV AIDS, Vancouver, Canada
    J Epidemiol Community Health 65:834-40. 2011
    ..Anti-illicit-drug public-service announcements (PSAs) have become a cornerstone of drug policy in the USA. However, studies of the effectiveness of these interventions have not been subjected to a systematic evaluation...
  24. pmc EDTA chelation therapy for cardiovascular disease: a systematic review
    Dugald M R Seely
    Canadian College of Naturopathic Medicine, Toronto, Canada
    BMC Cardiovasc Disord 5:32. 2005
    ..To address this issue we conducted a systematic review to evaluate the best available evidence for the use of EDTA chelation therapy in the treatment of cardiovascular disease...
  25. pmc In the era of systematic reviews, does the size of an individual trial still matter
    Gordon H Guyatt
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    PLoS Med 5:e4. 2008
    ..Others point out that small trials can still be potentially misleading...
  26. pmc Dangerous journey: documenting the experience of Tibetan refugees
    Sonam Dolma
    Department of Political Science, York University, Toronto, Ontario
    Am J Public Health 96:2061-4. 2006
    ..Since the 1950 invasion of Tibet by China, Tibetan refugees have attempted to flee into Nepal over the Himalayan mountains. We documented the experiences of a group of refugees making this journey...
  27. doi request reprint Calculating additive treatment effects from multiple randomized trials provides useful estimates of combination therapies
    Edward J Mills
    Faculty of Health Sciences, University of Ottawa, 43 Templeton Street, Ottawa, Ontario, Canada
    J Clin Epidemiol 65:1282-8. 2012
    ..We discuss here the prerequisites and methods of applying additivity assumptions in synthesizing the evidence from randomized trials and multiple treatment meta-analyses...
  28. pmc Anti-tumor necrosis factor (TNF) drugs for the treatment of psoriatic arthritis: an indirect comparison meta-analysis
    Kristian Thorlund
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    Biologics 6:417-27. 2012
    ....
  29. pmc The Cameroon Mobile Phone SMS (CAMPS) trial: a randomized trial of text messaging versus usual care for adherence to antiretroviral therapy
    Lawrence Mbuagbaw
    Centre for the Development of Best Practices in Health CDBPH, Yaounde Central Hospital, Yaounde, Centre, Cameroon
    PLoS ONE 7:e46909. 2012
    ..This trial investigates the use of motivational mobile phone text messages (SMS) to improve adherence to antiretroviral therapy (ART) over six months...
  30. doi request reprint Comparisons of high-dose and combination nicotine replacement therapy, varenicline, and bupropion for smoking cessation: a systematic review and multiple treatment meta-analysis
    Edward J Mills
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    Ann Med 44:588-97. 2012
    ..This review compared the effect of high-dose nicotine replacement therapy (NRT) and combinations of NRT for increasing smoking abstinence rates compared to standard-dose NRT patch, varenicline, and bupropion on smoking abstinence...
  31. pmc Health system determinants of infant, child and maternal mortality: A cross-sectional study of UN member countries
    Katherine A Muldoon
    British Columbia Centre for Excellence in HIV AIDS, St, Paul s Hospital, 1081 Burrard Street, Vancouver, British Columbia, Canada
    Global Health 7:42. 2011
    ..abstract:..
  32. doi request reprint Safety of task-shifting for male medical circumcision: a systematic review and meta-analysis
    Nathan Ford
    Centre for Infectious Disease Epidemiology and Research, University of Cape Town, Cape Town, South Africa
    AIDS 26:559-66. 2012
    ..We undertook a systematic review and meta-analysis to review the safety of task-shifting for circumcision in Africa...
  33. pmc Livelihood security and adherence to antiretroviral therapy in low and middle income settings: a systematic review
    Beth S Rachlis
    Division of Epidemiology, Dalla Lana School of Public Health, University of Toronto, Toronto, Canada
    PLoS ONE 6:e18948. 2011
    ..We sought to examine the association between livelihood security and adherence to antiretroviral therapy (ARVs) in low- and middle-income countries (LIMC)...
  34. ncbi request reprint Systematically reviewing qualitative studies complements survey design: an exploratory study of barriers to paediatric immunisations
    Edward J Mills
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Health Science Centre, Hamilton, Ontario, Canada
    J Clin Epidemiol 58:1101-8. 2005
    ..We examined surveys addressing parental barriers to vaccinating children to determine if they comprehensively included themes identified in published qualitative studies...
  35. ncbi request reprint Disclosure of natural product use to primary care physicians: a cross-sectional survey of naturopathic clinic attendees
    Jason W Busse
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    Mayo Clin Proc 80:616-23. 2005
    ..To determine factors that predict disclosure of natural product use by patients to their primary care physicians...
  36. doi request reprint Naturopathic treatment of rotator cuff tendinitis among Canadian postal workers: a randomized controlled trial
    Orest Szczurko
    Canadian College of Naturopathic Medicine, Toronto, Ontario, Canada
    Arthritis Rheum 61:1037-45. 2009
    ..To explore the effectiveness of naturopathic care (NC) on rotator cuff tendinitis using a prospective randomized clinical trial design...
  37. doi request reprint HIV/AIDS in African militaries: an ecological analysis
    Oumar Ba
    Faculty of Health Sciences, Simon Fraser University, Vancouver, Canada
    Med Confl Surviv 24:88-100. 2008
    ..4). Population levels predicted military prevalence rates (P < or = 0.001). HIV/AIDS prevalence rates in most African militaries are significantly elevated compared to their host communities...
  38. pmc The abandoned trials of pre-exposure prophylaxis for HIV: what went wrong?
    Jerome A Singh
    Centre for the AIDS Programme of Research, South Africa
    PLoS Med 2:e234. 2005
  39. ncbi request reprint Randomized controlled trials in long-term care residents with dementia: a systematic review
    Edward J Mills
    The University of Oxford
    J Am Med Dir Assoc 4:302-7. 2003
    ..To evaluate the quality of reporting of randomized controlled trials for pharmacologic interventions in long-term care residents with dementia...
  40. ncbi request reprint The quality of randomized trial reporting in leading medical journals since the revised CONSORT statement
    Edward J Mills
    Department of Clinical Epidemiology and Biostatistics, Faculty of Health Sciences, McMaster University, HSC 2C12, 1200 Main Street West, Hamilton, ON, Canada, L8N 3Z5
    Contemp Clin Trials 26:480-7. 2005
    ..Although reporting of some CONSORT recommendations is high, reporting of several essential recommendations remains suboptimal. Authors need to comply with and journals need to enforce reporting of the revised CONSORT recommendations...
  41. ncbi request reprint Migration and transmission of blood-borne infections among injection drug users: understanding the epidemiologic bridge
    Beth Rachlis
    BC Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, British Columbia, Canada
    Drug Alcohol Depend 90:107-19. 2007
    ..We also discuss the potential policy implications of addressing prevention and care issues in mobile drug using populations...
  42. ncbi request reprint Violence-related mortality in Iraq, 2002-2006
    Edward J Mills
    N Engl J Med 359:432; author reply 434. 2008
  43. ncbi request reprint Neglected diseases, civil conflicts, and the right to health
    Chris Beyrer
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Lancet 370:619-27. 2007
    ..We also discuss the role of researchers in advocating for and researching within oppressed populations...
  44. pmc Designing research in vulnerable populations: lessons from HIV prevention trials that stopped early
    Edward J Mills
    Department of Clinical Epidemiology and Biostatistics, McMaster University, HSC 2C12, 1200 Main Street West, Hamilton, ON, Canada L8N 3Z5
    BMJ 331:1403-6. 2005
  45. ncbi request reprint HIV infection as a weapon of war
    Edward J Mills
    Lancet Infect Dis 6:752-3. 2006
  46. ncbi request reprint Participation in HIV vaccine trials: listening to participant & community concerns
    Edward J Mills
    B C Centre for Excellence in HIV AIDS, St Paul s Hospital Vancouver BC
    Indian J Med Res 124:608-10. 2006
  47. pmc Problems with use of composite end points in cardiovascular trials: systematic review of randomised controlled trials
    Ignacio Ferreira-Gonzalez
    Departament de Medicina, Universitat Autonoma de Barcelona, and Hospital Vall d Hebron, Barcelona 08035, Spain
    BMJ 334:786. 2007
    ....