Simple, effective interventions are key to improving adherence in marginalized populationsEdward J Mills
Clin Infect Dis 45:916-7. 2007
- The impact of conflict on HIV/AIDS in sub-Saharan Africa
Edward J Mills
Centre for International Health and Human Rights Studies, Toronto, Canada
Int J STD AIDS 17:713-7. 2006
..We examine the complexity of monitoring HIV/AIDS in conflict settings. We argue that increased efforts are needed to protect vulnerable populations and design health-delivery systems that are sustainable in settings of conflict...
- Adherence to antiretroviral therapy in sub-Saharan Africa and North America: a meta-analysis
Edward J Mills
Centre for International Health and Human Rights Studies, Toronto, Ontario, Canada
JAMA 296:679-90. 2006
..Concerns about incomplete adherence among patients living in poverty have been an important consideration in expanding the access to antiretroviral therapy in sub-Saharan Africa...
- Randomized trials stopped early for harm in HIV/AIDS: a systematic survey
Edward Mills
Centre for International Health and Human Rights Studies, North York, Ontario, Canada
HIV Clin Trials 7:24-33. 2006
..We assessed the prevalence of randomized clinical trials (RCTs) stopped early for harm in HIV/AIDS and determined the quality of reporting of methods to inform the decision to stop the trial...
- Should active recruitment of health workers from sub-Saharan Africa be viewed as a crime?
Edward J Mills
British Columbia Centre for Excellence in HIV AIDS, University of British Columbia, Canada
Lancet 371:685-8. 2008
Adherence to HAART: a systematic review of developed and developing nation patient-reported barriers and facilitatorsEdward J Mills
Centre for International Health and Human Rights Studies, Toronto, Ontario, Canada
PLoS Med 3:e438. 2006
..We systematically reviewed the literature to determine patient-reported barriers and facilitators to adhering to antiretroviral therapy...
- Naturopathic care for chronic low back pain: a randomized trial
Orest Szczurko
Division of Clinical Epidemiology, Canadian College of Naturopathic Medicine, Toronto, Ontario, Canada
PLoS ONE 2:e919. 2007
..Chronic low back pain represents a substantial cost to employers through benefits coverage and days missed due to incapacity. We sought to explore the effectiveness of Naturopathic care on chronic low back pain...
- Naturopathic care for anxiety: a randomized controlled trial ISRCTN78958974
Kieran Cooley
Department of Research and Clinical Epidemiology, The Canadian College of Naturopathic Medicine, Toronto, Canada
PLoS ONE 4:e6628. 2009
..This study sought to explore the effectiveness of naturopathic care on anxiety symptoms using a randomized trial...
Male sex and the risk of mortality among individuals enrolled in antiretroviral therapy programs in Africa: a systematic review and meta-analysisEric Druyts
Faculty of Health Sciences, University of Ottawa, Ottawa, Ontario, Canada
AIDS 27:417-25. 2013
..HIV/AIDS has historically had a sex and gender-focused approach to prevention and care. Some evidence suggests that HIV-positive men have worse treatment outcomes than their women counterparts in Africa...
- Life expectancy of persons receiving combination antiretroviral therapy in low-income countries: a cohort analysis from Uganda
Edward J Mills
University of Ottawa, Ottawa, Ontario, Canada
Ann Intern Med 155:209-16. 2011
..Little is known about the effect of combination antiretroviral therapy (cART) on life expectancy in sub-Saharan Africa...
- Primary prevention of cardiovascular mortality and events with statin treatments: a network meta-analysis involving more than 65,000 patients
Edward J Mills
Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
J Am Coll Cardiol 52:1769-81. 2008
..This study aimed to evaluate the effectiveness of 3-hydroxy-3-methyl-glutaryl-CoA reductase inhibitors (statins) in primary prevention of cardiovascular events...
- Long-Term Health Care Interruptions Among HIV-Positive Patients in Uganda
Edward J Mills
Faculty of Health Sciences, University of Ottawa, Ottawa, Ontario, Canada Stanford Prevention Research Center, School of Medicine, Stanford University, Stanford, CA Mildmay Uganda, Kampala, Uganda Division of Infectious Diseases, The Ottawa Hospital, Ottawa, Ontario, Canada Centre for Infectious Diseases, Stellenbosch University, Cape Town, South Africa and Médecins Sans Frontières, Geneva, Switzerland
J Acquir Immune Defic Syndr 63:e23-7. 2013
..We examined risk factors for health care interruptions and loss to follow-up within a cohort receiving ART in Uganda...
- Low-dose aspirin and cancer mortality: a meta-analysis of randomized trials
Edward J Mills
Faculty of Health Sciences, University of Ottawa, Ontario, Canada
Am J Med 125:560-7. 2012
..We aimed to determine whether cancer mortality also is reduced by low-dose aspirin in the shorter term...
- Stopping randomized trials early for benefit and estimation of treatment effects: systematic review and meta-regression analysis
Dirk Bassler
Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
JAMA 303:1180-7. 2010
..Theory and simulation suggest that randomized controlled trials (RCTs) stopped early for benefit (truncated RCTs) systematically overestimate treatment effects for the outcome that precipitated early stopping...
- A wake-up call for global access to salvage HIV drug regimens
Edward J Mills
British Columbia Centre for Excellence in HIV/AIDS, Vancouver, BC, Canada
Lancet 370:1885-7. 2007
- The effects of green tea consumption on incidence of breast cancer and recurrence of breast cancer: a systematic review and meta-analysis
Dugald Seely
Department of Clinical Epidemiology, Canadian College of Naturopathic Medicine, Toronto, Ontario, Canada
Integr Cancer Ther 4:144-55. 2005
..Green tea is widely used by women for the prevention and treatment of breast cancer. The authors aimed to determine the efficacy of green tea ingestion on the risk of breast cancer development and the risk of breast cancer recurrence...
- Epidemiology and reporting of randomized trials employing re-randomization of patient groups: a systematic survey
Edward J Mills
Department of Clinical Epidemiology and Biostatistics, McMaster University, 1200 Main Street West, Hamilton, Ontario, Canada
Contemp Clin Trials 28:268-75. 2007
....
- The effectiveness of anti-illicit-drug public-service announcements: a systematic review and meta-analysis
Dan Werb
British Columbia Centre for Excellence in HIV AIDS, Vancouver, Canada
J Epidemiol Community Health 65:834-40. 2011
..Anti-illicit-drug public-service announcements (PSAs) have become a cornerstone of drug policy in the USA. However, studies of the effectiveness of these interventions have not been subjected to a systematic evaluation...
- Design and methods of the MAINTAIN study: a randomized controlled clinical trial of micronutrient and antioxidant supplementation in untreated HIV infection
Neera Singhal
Department of Medicine, University of Ottawa at Ottawa Hospital Research Institute, Ottawa, Ontario, Canada
Contemp Clin Trials 31:604-11. 2010
..We discuss here the study design and methods, often used for evaluation of complementary and adjunctive treatments for health maintenance in HIV infection, which are common interventions...
- Dangerous journey: documenting the experience of Tibetan refugees
Sonam Dolma
Department of Political Science, York University, Toronto, Ontario
Am J Public Health 96:2061-4. 2006
..International pressure is needed to prevent human rights violations and reduce potential long-term physical and mental health effects associated with this dangerous crossing...
- EDTA chelation therapy for cardiovascular disease: a systematic review
Dugald M R Seely
Canadian College of Naturopathic Medicine, Toronto, Canada
BMC Cardiovasc Disord 5:32. 2005
..To address this issue we conducted a systematic review to evaluate the best available evidence for the use of EDTA chelation therapy in the treatment of cardiovascular disease...
- In the era of systematic reviews, does the size of an individual trial still matter
Gordon H Guyatt
Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
PLoS Med 5:e4. 2008
..Others point out that small trials can still be potentially misleading...
- The Cameroon Mobile Phone SMS (CAMPS) trial: a randomized trial of text messaging versus usual care for adherence to antiretroviral therapy
Lawrence Mbuagbaw
Centre for the Development of Best Practices in Health CDBPH, Yaounde Central Hospital, Yaounde, Centre, Cameroon
PLoS ONE 7:e46909. 2012
..This trial investigates the use of motivational mobile phone text messages (SMS) to improve adherence to antiretroviral therapy (ART) over six months...
- Anti-tumor necrosis factor (TNF) drugs for the treatment of psoriatic arthritis: an indirect comparison meta-analysis
Kristian Thorlund
Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
Biologics 6:417-27. 2012
....
- Health system determinants of infant, child and maternal mortality: A cross-sectional study of UN member countries
Katherine A Muldoon
British Columbia Centre for Excellence in HIV AIDS, St, Paul s Hospital, 1081 Burrard Street, Vancouver, British Columbia, Canada
Global Health 7:42. 2011
..abstract:..
- Risk of resistance to highly active antiretroviral therapy among HIV-positive injecting drug users: a meta-analysis
Daniel Werb
British Columbia Centre for Excellence in HIV AIDS, University of British Columbia, 608 1081 Burrard Street, Vancouver, BC, Canada
Lancet Infect Dis 10:464-9. 2010
..Therapeutic guidelines should consider reassessment of this issue...
- Comparisons of high-dose and combination nicotine replacement therapy, varenicline, and bupropion for smoking cessation: a systematic review and multiple treatment meta-analysis
Edward J Mills
Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
Ann Med 44:588-97. 2012
..This review compared the effect of high-dose nicotine replacement therapy (NRT) and combinations of NRT for increasing smoking abstinence rates compared to standard-dose NRT patch, varenicline, and bupropion on smoking abstinence...
- Safety of task-shifting for male medical circumcision: a systematic review and meta-analysis
Nathan Ford
Centre for Infectious Disease Epidemiology and Research, University of Cape Town, Cape Town, South Africa
AIDS 26:559-66. 2012
..We undertook a systematic review and meta-analysis to review the safety of task-shifting for circumcision in Africa...
- Naturopathic treatment of rotator cuff tendinitis among Canadian postal workers: a randomized controlled trial
Orest Szczurko
Canadian College of Naturopathic Medicine, Toronto, Ontario, Canada
Arthritis Rheum 61:1037-45. 2009
..To explore the effectiveness of naturopathic care (NC) on rotator cuff tendinitis using a prospective randomized clinical trial design...
- Livelihood security and adherence to antiretroviral therapy in low and middle income settings: a systematic review
Beth S Rachlis
Division of Epidemiology, Dalla Lana School of Public Health, University of Toronto, Toronto, Canada
PLoS ONE 6:e18948. 2011
..We sought to examine the association between livelihood security and adherence to antiretroviral therapy (ARVs) in low- and middle-income countries (LIMC)...
- Systematically reviewing qualitative studies complements survey design: an exploratory study of barriers to paediatric immunisations
Edward J Mills
Department of Clinical Epidemiology and Biostatistics, McMaster University, Health Science Centre, Hamilton, Ontario, Canada
J Clin Epidemiol 58:1101-8. 2005
..We examined surveys addressing parental barriers to vaccinating children to determine if they comprehensively included themes identified in published qualitative studies...
- Disclosure of natural product use to primary care physicians: a cross-sectional survey of naturopathic clinic attendees
Jason W Busse
Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
Mayo Clin Proc 80:616-23. 2005
..Our findings suggest that disclosure rates could be improved by physicians taking a more active role in asking their patients about natural product use...
- HIV/AIDS in African militaries: an ecological analysis
Oumar Ba
Faculty of Health Sciences, Simon Fraser University, Vancouver, Canada
Med Confl Surviv 24:88-100. 2008
..4). Population levels predicted military prevalence rates (P < or = 0.001). HIV/AIDS prevalence rates in most African militaries are significantly elevated compared to their host communities...
- The abandoned trials of pre-exposure prophylaxis for HIV: what went wrong?
Jerome A Singh
Centre for the AIDS Programme of Research, South Africa
PLoS Med 2:e234. 2005
- Participation in HIV vaccine trials: listening to participant & community concerns
Edward J Mills
B.C. Centre for Excellence in HIV/AIDS, St. Paul's Hospital Vancouver BC
Indian J Med Res 124:608-10. 2006
- Migration and transmission of blood-borne infections among injection drug users: understanding the epidemiologic bridge
Beth Rachlis
BC Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, British Columbia, Canada
Drug Alcohol Depend 90:107-19. 2007
..We also discuss the potential policy implications of addressing prevention and care issues in mobile drug using populations...
- Neglected diseases, civil conflicts, and the right to health
Chris Beyrer
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
Lancet 370:619-27. 2007
..We also discuss the role of researchers in advocating for and researching within oppressed populations...
- Randomized controlled trials in long-term care residents with dementia: a systematic review
Edward J Mills
The University of Oxford
J Am Med Dir Assoc 4:302-7. 2003
..The reporting quality is highly variable in the trials reviewed, and concerns exist surrounding the conduct of several trials...
- Designing research in vulnerable populations: lessons from HIV prevention trials that stopped early
Edward J Mills
Department of Clinical Epidemiology and Biostatistics, McMaster University, HSC-2C12, 1200 Main Street West, Hamilton, ON, Canada L8N 3Z5
BMJ 331:1403-6. 2005
- Violence-related mortality in Iraq, 2002-2006
Edward J Mills
N Engl J Med 359:432; author reply 434. 2008
- Problems with use of composite end points in cardiovascular trials: systematic review of randomised controlled trials
Ignacio Ferreira Gonzalez
Departament de Medicina, Universitat Autonoma de Barcelona, and Hospital Vall d Hebron, Barcelona 08035, Spain
BMJ 334:786. 2007
....
- The quality of randomized trial reporting in leading medical journals since the revised CONSORT statement
Edward J Mills
Department of Clinical Epidemiology and Biostatistics, Faculty of Health Sciences, McMaster University, HSC 2C12, 1200 Main Street West, Hamilton, ON, Canada, L8N 3Z5
Contemp Clin Trials 26:480-7. 2005
..Although reporting of some CONSORT recommendations is high, reporting of several essential recommendations remains suboptimal. Authors need to comply with and journals need to enforce reporting of the revised CONSORT recommendations...
- HIV infection as a weapon of war
Edward J Mills
Lancet Infect Dis 6:752-3. 2006
