Neuromotor, cognitive, language and behavioural outcome in children born following IVF or ICSI-a systematic reviewK J Middelburg
Department of Paediatrics, Division of Developmental Neurology, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
Hum Reprod Update 14:219-31. 2008
..The objective of this study is to evaluate neurodevelopmental (ND) outcome of children born following these techniques...
- Ovarian hyperstimulation and the in vitro fertilization procedure do not influence early neuromotor development; a history of subfertility does
Karin J Middelburg
Division of Developmental Neurology, Department of Pediatrics, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
Fertil Steril 93:544-53. 2010
..To evaluate specific effects of ovarian hyperstimulation, the in vitro procedure, and a history of subfertility on neuromotor development at 3 months of age...
- Mental, psychomotor, neurologic, and behavioral outcomes of 2-year-old children born after preimplantation genetic screening: follow-up of a randomized controlled trial
Karin J Middelburg
Department of Pediatrics, Division of Developmental Neurology, University Medical Center, Groningen, The Netherlands
Fertil Steril 96:165-9. 2011
..To evaluate the effect of preimplantation genetic screening (PGS) on neurodevelopmental outcomes in children...
- The Groningen ART cohort study: ovarian hyperstimulation and the in vitro procedure do not affect neurological outcome in infancy
K J Middelburg
Department of Paediatrics, Division of Developmental Neurology CA85, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
Hum Reprod 24:3119-26. 2009
..The aim of the present study was to evaluate the specific effects of ovarian hyperstimulation and the in vitro procedure on neurological outcome in 4-18-month-old children...
- Neurological condition of infants born after in vitro fertilization with preimplantation genetic screening
Karin J Middelburg
Departments of Pediatrics, University Medical Center Groningen, The Netherlands
Pediatr Res 67:430-4. 2010
..The small sample size precludes the conclusion that PGS is not associated with less favorable neurologic outcome. Safety of new assisted reproductive techniques should be evaluated before large-scale implementation. ABBREVIATIONS::..
- The Groningen assisted reproductive technologies cohort study: developmental status and behavior at 2 years
Marjolein Jongbloed-Pereboom
Department of Pediatrics, Division of Developmental Neurology, University Medical Center Groningen, Groningen, The Netherlands
Fertil Steril 95:2283-9. 2011
..To evaluate whether children's cognitive and psychomotor development and behavior at 2 years are affected by ovarian hyperstimulation and the IVF laboratory procedures or subfertility...
- Construct validity of the Infant Motor Profile: relation with prenatal, perinatal, and neonatal risk factors
Kirsten R Heineman
Department of Paediatrics, Institute of Developmental Neurology, University Medical Center Groningen, Groningen, The Netherlands
Dev Med Child Neurol 52:e209-15. 2010
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- Movement variation in infants born following IVF/ICSI with and without ovarian hyperstimulation
Pamela Schendelaar
Dept of Paediatrics, Div of Developmental Neurology CA 85, University Medical Center Groningen, Hanzeplein 1, 9713 GZ, Groningen, The Netherlands
Early Hum Dev 89:507-13. 2013
..It includes the evaluation of movement variation (i.e. movement repertoire size), a parameter reflecting the integrity of cortical connectivity...
- Dysmorphic features in 2-year-old IVF/ICSI offspring
Jorien Seggers
Dept Pediatrics, Div Developmental Neurology, University Medical Center Groningen, The Netherlands
Early Hum Dev 88:823-9. 2012
..This study evaluates the effects of ovarian hyperstimulation, the in vitro procedure and time to pregnancy (TTP) - as proxy for the severity of subfertility - on the prevalence of dysmorphic features...
- The assessment of minor neurological dysfunction in infancy using the Touwen Infant Neurological Examination: strengths and limitations
Mijna Hadders-Algra
Department of Paediatrics and Developmental Neurology, University Medical Center Groningen, Groningen, The Netherlands
Dev Med Child Neurol 52:87-92. 2010
..This study aimed to evaluate the inter-assessor reliability of the assessment of MND with the Touwen Infant Neurological Examination (TINE) and the construct and predictive validity of MND in infancy...
- Reliability and concurrent validity of the Infant Motor Profile
Kirsten R Heineman
Department of Paediatrics, Institute of Developmental Neurology, University Medical Center Groningen, Groningen, The Netherlands Department of Neurology, University Medical Center Groningen, Groningen, The Netherlands
Dev Med Child Neurol 55:539-45. 2013
..The aim of this study was to assess interobserver reliability and concurrent validity of the IMP with the Alberta Infant Motor Scale (AIMS) and an age-specific neurological examination...
- Maternal anxiety is related to infant neurological condition, paternal anxiety is not
Hedwig K Kikkert
Dept of Paediatrics, Developmental Neurology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, Groningen, The Netherlands
Early Hum Dev 86:171-7. 2010
..Parental anxiety and stress may have consequences for infant neurological development...
- Is the birthweight of singletons born after IVF reduced by ovarian stimulation or by IVF laboratory procedures?
M J Pelinck
Section of Reproductive Medicine, Department of Obstetrics and Gynaecology, University Medical Center Groningen, Groningen, The Netherlands
Reprod Biomed Online 21:245-51. 2010
..Second, the IVF laboratory procedure has no influence on birthweight. Third, although a trend towards lower birthweight after ovarian stimulation was found, an adverse effect of ovarian stimulation on birthweight was not substantiated...
- Development of adaptive motor behaviour in typically developing infants
K R Heineman
Department of Paediatrics Developmental Neurology, University Medical Center Groningen, Groningen, The Netherlands
Acta Paediatr 99:618-24. 2010
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