Karin J Middelburg

Summary

Publications

  1. doi request reprint Neuromotor, cognitive, language and behavioural outcome in children born following IVF or ICSI-a systematic review
    K J Middelburg
    Department of Paediatrics, Division of Developmental Neurology, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
    Hum Reprod Update 14:219-31. 2008
  2. doi request reprint Ovarian hyperstimulation and the in vitro fertilization procedure do not influence early neuromotor development; a history of subfertility does
    Karin J Middelburg
    Division of Developmental Neurology, Department of Pediatrics, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
    Fertil Steril 93:544-53. 2010
  3. doi request reprint Mental, psychomotor, neurologic, and behavioral outcomes of 2-year-old children born after preimplantation genetic screening: follow-up of a randomized controlled trial
    Karin J Middelburg
    Department of Pediatrics, Division of Developmental Neurology, University Medical Center, Groningen, The Netherlands
    Fertil Steril 96:165-9. 2011
  4. doi request reprint The Groningen ART cohort study: ovarian hyperstimulation and the in vitro procedure do not affect neurological outcome in infancy
    K J Middelburg
    Department of Paediatrics, Division of Developmental Neurology CA85, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
    Hum Reprod 24:3119-26. 2009
  5. doi request reprint Neurological condition of infants born after in vitro fertilization with preimplantation genetic screening
    Karin J Middelburg
    Departments of Pediatrics, University Medical Center Groningen, The Netherlands
    Pediatr Res 67:430-4. 2010
  6. doi request reprint The Groningen assisted reproductive technologies cohort study: developmental status and behavior at 2 years
    Marjolein Jongbloed-Pereboom
    Department of Pediatrics, Division of Developmental Neurology, University Medical Center Groningen, Groningen, The Netherlands
    Fertil Steril 95:2283-9. 2011
  7. pmc Increased time to pregnancy is associated with suboptimal neurological condition of 2-year-olds
    Jorien Seggers
    Department of Paediatrics, Division of Developmental Neurology, University of Groningen, University Medical Center Groningen, The Netherlands
    Arch Dis Child Fetal Neonatal Ed 98:F434-6. 2013
  8. doi request reprint Reliability and concurrent validity of the Infant Motor Profile
    Kirsten R Heineman
    Department of Paediatrics, Institute of Developmental Neurology, University Medical Center Groningen, Groningen, The Netherlands
    Dev Med Child Neurol 55:539-45. 2013
  9. doi request reprint Movement variation in infants born following IVF/ICSI with and without ovarian hyperstimulation
    Pamela Schendelaar
    Dept of Paediatrics, Div of Developmental Neurology CA 85, University Medical Center Groningen, Hanzeplein 1, 9713 GZ, Groningen, The Netherlands
    Early Hum Dev 89:507-13. 2013
  10. doi request reprint Construct validity of the Infant Motor Profile: relation with prenatal, perinatal, and neonatal risk factors
    Kirsten R Heineman
    Department of Paediatrics, Institute of Developmental Neurology, University Medical Center Groningen, Groningen, The Netherlands
    Dev Med Child Neurol 52:e209-15. 2010

Collaborators

Detail Information

Publications18

  1. doi request reprint Neuromotor, cognitive, language and behavioural outcome in children born following IVF or ICSI-a systematic review
    K J Middelburg
    Department of Paediatrics, Division of Developmental Neurology, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
    Hum Reprod Update 14:219-31. 2008
    ..The objective of this study is to evaluate neurodevelopmental (ND) outcome of children born following these techniques...
  2. doi request reprint Ovarian hyperstimulation and the in vitro fertilization procedure do not influence early neuromotor development; a history of subfertility does
    Karin J Middelburg
    Division of Developmental Neurology, Department of Pediatrics, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
    Fertil Steril 93:544-53. 2010
    ..To evaluate specific effects of ovarian hyperstimulation, the in vitro procedure, and a history of subfertility on neuromotor development at 3 months of age...
  3. doi request reprint Mental, psychomotor, neurologic, and behavioral outcomes of 2-year-old children born after preimplantation genetic screening: follow-up of a randomized controlled trial
    Karin J Middelburg
    Department of Pediatrics, Division of Developmental Neurology, University Medical Center, Groningen, The Netherlands
    Fertil Steril 96:165-9. 2011
    ..To evaluate the effect of preimplantation genetic screening (PGS) on neurodevelopmental outcomes in children...
  4. doi request reprint The Groningen ART cohort study: ovarian hyperstimulation and the in vitro procedure do not affect neurological outcome in infancy
    K J Middelburg
    Department of Paediatrics, Division of Developmental Neurology CA85, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
    Hum Reprod 24:3119-26. 2009
    ..The aim of the present study was to evaluate the specific effects of ovarian hyperstimulation and the in vitro procedure on neurological outcome in 4-18-month-old children...
  5. doi request reprint Neurological condition of infants born after in vitro fertilization with preimplantation genetic screening
    Karin J Middelburg
    Departments of Pediatrics, University Medical Center Groningen, The Netherlands
    Pediatr Res 67:430-4. 2010
    ..The small sample size precludes the conclusion that PGS is not associated with less favorable neurologic outcome. Safety of new assisted reproductive techniques should be evaluated before large-scale implementation...
  6. doi request reprint The Groningen assisted reproductive technologies cohort study: developmental status and behavior at 2 years
    Marjolein Jongbloed-Pereboom
    Department of Pediatrics, Division of Developmental Neurology, University Medical Center Groningen, Groningen, The Netherlands
    Fertil Steril 95:2283-9. 2011
    ..To evaluate whether children's cognitive and psychomotor development and behavior at 2 years are affected by ovarian hyperstimulation and the IVF laboratory procedures or subfertility...
  7. pmc Increased time to pregnancy is associated with suboptimal neurological condition of 2-year-olds
    Jorien Seggers
    Department of Paediatrics, Division of Developmental Neurology, University of Groningen, University Medical Center Groningen, The Netherlands
    Arch Dis Child Fetal Neonatal Ed 98:F434-6. 2013
    ..To evaluate whether time to pregnancy (TTP) is associated with neurological condition of 2-year-old children born to subfertile parents...
  8. doi request reprint Reliability and concurrent validity of the Infant Motor Profile
    Kirsten R Heineman
    Department of Paediatrics, Institute of Developmental Neurology, University Medical Center Groningen, Groningen, The Netherlands
    Dev Med Child Neurol 55:539-45. 2013
    ..The aim of this study was to assess interobserver reliability and concurrent validity of the IMP with the Alberta Infant Motor Scale (AIMS) and an age-specific neurological examination...
  9. doi request reprint Movement variation in infants born following IVF/ICSI with and without ovarian hyperstimulation
    Pamela Schendelaar
    Dept of Paediatrics, Div of Developmental Neurology CA 85, University Medical Center Groningen, Hanzeplein 1, 9713 GZ, Groningen, The Netherlands
    Early Hum Dev 89:507-13. 2013
    ..It includes the evaluation of movement variation (i.e. movement repertoire size), a parameter reflecting the integrity of cortical connectivity...
  10. doi request reprint Construct validity of the Infant Motor Profile: relation with prenatal, perinatal, and neonatal risk factors
    Kirsten R Heineman
    Department of Paediatrics, Institute of Developmental Neurology, University Medical Center Groningen, Groningen, The Netherlands
    Dev Med Child Neurol 52:e209-15. 2010
    ....
  11. doi request reprint Is ovarian hyperstimulation associated with higher blood pressure in 4-year-old IVF offspring? Part I: multivariable regression analysis
    Jorien Seggers
    Department of Paediatrics, Division of Developmental Neurology CA 85, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
    Hum Reprod 29:502-9. 2014
    ..Does ovarian hyperstimulation, the in vitro procedure, or a combination of these two negatively influence blood pressure (BP) and anthropometrics of 4-year-old children born following IVF?..
  12. doi request reprint Is ovarian hyperstimulation associated with higher blood pressure in 4-year-old IVF offspring? Part II: an explorative causal inference approach
    Sacha La Bastide-Van Gemert
    Department Epidemiology, University of Groningen, University Medical Center Groningen, Hanzeplein 1, Groningen 9713 GZ, The Netherlands
    Hum Reprod 29:510-7. 2014
    ..What causal relationships underlie the associations between ovarian stimulation, the IVF procedure, parental-, fertility- and child characteristics, and blood pressure (BP) and anthropometrics of 4-year-old IVF children?..
  13. doi request reprint Blood pressure and anthropometrics of 4-y-old children born after preimplantation genetic screening: follow-up of a unique, moderately sized, randomized controlled trial
    Jorien Seggers
    Division of Developmental Neurology, Department of Paediatrics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
    Pediatr Res 74:606-14. 2013
    ..It is unknown whether preimplantation genetic screening (PGS), which involves embryo biopsy, affects blood pressure (BP), anthropometrics, and the frequency of received medical care...
  14. doi request reprint Dysmorphic features in 2-year-old IVF/ICSI offspring
    Jorien Seggers
    Dept Pediatrics, Div Developmental Neurology, University Medical Center Groningen, The Netherlands
    Early Hum Dev 88:823-9. 2012
    ..This study evaluates the effects of ovarian hyperstimulation, the in vitro procedure and time to pregnancy (TTP) - as proxy for the severity of subfertility - on the prevalence of dysmorphic features...
  15. doi request reprint The assessment of minor neurological dysfunction in infancy using the Touwen Infant Neurological Examination: strengths and limitations
    Mijna Hadders-Algra
    Department of Paediatrics and Developmental Neurology, University Medical Center Groningen, Groningen, The Netherlands
    Dev Med Child Neurol 52:87-92. 2010
    ..This study aimed to evaluate the inter-assessor reliability of the assessment of MND with the Touwen Infant Neurological Examination (TINE) and the construct and predictive validity of MND in infancy...
  16. doi request reprint Maternal anxiety is related to infant neurological condition, paternal anxiety is not
    Hedwig K Kikkert
    Dept of Paediatrics, Developmental Neurology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, Groningen, The Netherlands
    Early Hum Dev 86:171-7. 2010
    ..Parental anxiety and stress may have consequences for infant neurological development...
  17. doi request reprint Development of adaptive motor behaviour in typically developing infants
    K R Heineman
    Department of Paediatrics Developmental Neurology, University Medical Center Groningen, Groningen, The Netherlands
    Acta Paediatr 99:618-24. 2010
    ....
  18. doi request reprint Is the birthweight of singletons born after IVF reduced by ovarian stimulation or by IVF laboratory procedures?
    M J Pelinck
    Section of Reproductive Medicine, Department of Obstetrics and Gynaecology, University Medical Center Groningen, Groningen, The Netherlands
    Reprod Biomed Online 21:245-51. 2010
    ..Second, the IVF laboratory procedure has no influence on birthweight. Third, although a trend towards lower birthweight after ovarian stimulation was found, an adverse effect of ovarian stimulation on birthweight was not substantiated...