G Soldevila

Summary

Country: Mexico

Publications

  1. pmc Jak3 enables chemokine-dependent actin cytoskeleton reorganization by regulating cofilin and Rac/Rhoa GTPases activation
    Xochitl Ambriz-Peña
    Departamento de Inmunologia, Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, Mexico, Distrito Federal, Mexico
    PLoS ONE 9:e88014. 2014
  2. pmc Betaglycan (TβRIII) is expressed in the thymus and regulates T cell development by protecting thymocytes from apoptosis
    German R Aleman-Muench
    Departamento de Inmunologia, Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, Mexico, Mexico
    PLoS ONE 7:e44217. 2012
  3. pmc High glucose concentrations induce TNF-α production through the down-regulation of CD33 in primary human monocytes
    Yolanda Gonzalez
    Departamento de investigación en microbiología, Instituto Nacional de Enfermedades Respiratorias, Calzada de Tlalpan 4502, Seccion XVI, Ciudad de Mexico, 14080, Mexico
    BMC Immunol 13:19. 2012
  4. ncbi request reprint Analysis of the individual role of the TCRzeta chain in transgenic mice after conditional activation with chemical inducers of dimerization
    G Soldevila
    Departamento de Inmunologia, Universidad Nacional Autonoma de Mexico, Mexico DF, Mexico
    Cell Immunol 214:123-38. 2001
  5. pmc Impaired chemokine-induced migration during T-cell development in the absence of Jak 3
    Gloria Soldevila
    Departamento de Inmunologia, Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, Mexico
    Immunology 112:191-200. 2004
  6. pmc The immunomodulatory properties of the CD5 lymphocyte receptor in health and disease
    Gloria Soldevila
    Departamento de Inmunologia, Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico UNAM, Circuito Escolar s n, Aptdo Postal 70228, Ciudad Universitaria, Mexico, DF 04510, Mexico
    Curr Opin Immunol 23:310-8. 2011
  7. doi request reprint Proteolytic cleavage of chemokines by Trypanosoma cruzi's cruzipain inhibits chemokine functions by promoting the generation of antagonists
    I Benítez-Hernández
    Departamento de Inmunologia, Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, Mexico, D F CP 04510, Mexico
    Immunobiology 215:413-26. 2010
  8. pmc Janus kinase 3-deficient T lymphocytes have an intrinsic defect in CCR7-mediated homing to peripheral lymphoid organs
    Eduardo A Garcia-Zepeda
    Departamento de Inmunologia, Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, Mexico
    Immunology 122:247-60. 2007
  9. ncbi request reprint A CCL chemokine-derived peptide (CDIP-2) exerts anti-inflammatory activity via CCR1, CCR2 and CCR3 chemokine receptors: Implications as a potential therapeutic treatment of asthma
    E Mendez-Enriquez
    CBRL, Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, Mexico, D F 04510, México Departamento de Inmunología, Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, Mexico, D F 04510, Mexico
    Int Immunopharmacol 20:1-11. 2014
  10. doi request reprint When versatility matters: activins/inhibins as key regulators of immunity
    G R Aleman-Muench
    Departamento de Inmunologia, Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, Ciudad Universitaria, Mexico City, Mexico
    Immunol Cell Biol 90:137-48. 2012

Collaborators

  • Isaura Meza
  • Francisco Lozano
  • J Ventura-Juarez
  • Chander Raman
  • Gloria Benitez-King
  • Eduardo A Garcia-Zepeda
  • E Mendez-Enriquez
  • E A Garcia-Zepeda
  • T I Fortoul
  • Diana Ordoñez-Rueda
  • Xochitl Ambriz-Peña
  • L Flores-Romo
  • M Ustarroz-Cano
  • A E Rojas-López
  • G R Aleman-Muench
  • Yolanda Gonzalez
  • German R Aleman-Muench
  • I Benítez-Hernández
  • Julio E Valdivia-Silva
  • Karen Nava
  • Ana Rivas-Caicedo
  • Adelaida Sarukhan
  • Francisco Martínez-Becerra
  • P Licona-Limón
  • Paula Licona
  • S Pertuz Belloso
  • Amaranta Rivas-Carvalho
  • Eduardo Alberto García-Zepeda
  • J Medina-Tamayo
  • B Anton
  • Guadalupe Fabián
  • G Pinon-Zarate
  • Eduardo Sada
  • Valentin Mendoza
  • E Martha Pérez-Armendariz
  • Kaye Stenvers
  • Karen Bobadilla
  • P Ostoa-Saloma
  • Fernando Lopez-Casillas
  • G Dupont
  • M Teresa Herrera
  • I García-Peláez
  • S Meza-Perez
  • M A Wurbel
  • M Herrera-Enriquez
  • Lourdes García-García
  • Martha Torres
  • Silvia Guzmán-Beltrán
  • F Cerban
  • T Fortoul
  • P Ostoa
  • J A Ramirez
  • C Stempin
  • Ana Luisa Esparza Silva
  • Leopoldo Flores-Romo
  • Jesús R Chávez-Rios
  • Janusz Franco-Barraza
  • Andrés Castell-Rodríguez
  • Gisela Du Pont
  • Teresa I Fortoul
  • G Baay
  • Y Melendez
  • F Martinez
  • S Huerta-Yepez
  • C Gonzalez-Bonilla
  • Ileana Licona-Limón
  • Daniel Adriano Silva
  • Lenin Dominguez-Ramirez
  • Guillermo Mendoza-Hernandez
  • Yolanda Lopez-Vidal
  • M Fernanda Jiménez-Sólomon
  • Jesus Chimal-Monroy
  • Sandra Bajana
  • E Garcia-Zepeda
  • Marco A Meraz-Ríos
  • Carmen Sanchez-Torres
  • Miguel E Moreno-Garcia
  • A Olivos
  • I Benitez
  • P Ostoa Saloma
  • Leopoldo Santos-Argumedo

Detail Information

Publications22

  1. pmc Jak3 enables chemokine-dependent actin cytoskeleton reorganization by regulating cofilin and Rac/Rhoa GTPases activation
    Xochitl Ambriz-Peña
    Departamento de Inmunologia, Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, Mexico, Distrito Federal, Mexico
    PLoS ONE 9:e88014. 2014
    ..Our data support a new model in which Jak3 and heterotrimeric G proteins can use independent, but complementary, signaling pathways to regulate actin cytoskeleton dynamics during cell migration in response to chemokines...
  2. pmc Betaglycan (TβRIII) is expressed in the thymus and regulates T cell development by protecting thymocytes from apoptosis
    German R Aleman-Muench
    Departamento de Inmunologia, Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, Mexico, Mexico
    PLoS ONE 7:e44217. 2012
    ..These data suggest that Inhibins and TβRIII may function as a molecular pair regulating T cell development...
  3. pmc High glucose concentrations induce TNF-α production through the down-regulation of CD33 in primary human monocytes
    Yolanda Gonzalez
    Departamento de investigación en microbiología, Instituto Nacional de Enfermedades Respiratorias, Calzada de Tlalpan 4502, Seccion XVI, Ciudad de Mexico, 14080, Mexico
    BMC Immunol 13:19. 2012
    ..The expression of suppressor of cytokine signaling protein-3 (SOCS-3) and the generation of reactive oxygen species (ROS) were also evaluated to address the cellular mechanisms involved in the down-regulation of CD33...
  4. ncbi request reprint Analysis of the individual role of the TCRzeta chain in transgenic mice after conditional activation with chemical inducers of dimerization
    G Soldevila
    Departamento de Inmunologia, Universidad Nacional Autonoma de Mexico, Mexico DF, Mexico
    Cell Immunol 214:123-38. 2001
    ....
  5. pmc Impaired chemokine-induced migration during T-cell development in the absence of Jak 3
    Gloria Soldevila
    Departamento de Inmunologia, Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, Mexico
    Immunology 112:191-200. 2004
    ....
  6. pmc The immunomodulatory properties of the CD5 lymphocyte receptor in health and disease
    Gloria Soldevila
    Departamento de Inmunologia, Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico UNAM, Circuito Escolar s n, Aptdo Postal 70228, Ciudad Universitaria, Mexico, DF 04510, Mexico
    Curr Opin Immunol 23:310-8. 2011
    ..This review describes the current knowledge on the function of CD5 as an immunomodulatory receptor both in health and in disease...
  7. doi request reprint Proteolytic cleavage of chemokines by Trypanosoma cruzi's cruzipain inhibits chemokine functions by promoting the generation of antagonists
    I Benítez-Hernández
    Departamento de Inmunologia, Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, Mexico, D F CP 04510, Mexico
    Immunobiology 215:413-26. 2010
    ..This event could play a role during the latest phases of Chagas disease, when the parasite may differentially modulate chemokine-mediated inflammatory responses...
  8. pmc Janus kinase 3-deficient T lymphocytes have an intrinsic defect in CCR7-mediated homing to peripheral lymphoid organs
    Eduardo A Garcia-Zepeda
    Departamento de Inmunologia, Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, Mexico
    Immunology 122:247-60. 2007
    ..Our data demonstrates that Jak3(-/-) T lymphocytes have an intrinsic defect in CCR7-mediated homing to peripheral lymphoid organs...
  9. ncbi request reprint A CCL chemokine-derived peptide (CDIP-2) exerts anti-inflammatory activity via CCR1, CCR2 and CCR3 chemokine receptors: Implications as a potential therapeutic treatment of asthma
    E Mendez-Enriquez
    CBRL, Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, Mexico, D F 04510, México Departamento de Inmunología, Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, Mexico, D F 04510, Mexico
    Int Immunopharmacol 20:1-11. 2014
    ..These data suggest that chemokine-derived peptides represent new therapeutic tools to generate more effective antiinflammatory drugs. ..
  10. doi request reprint When versatility matters: activins/inhibins as key regulators of immunity
    G R Aleman-Muench
    Departamento de Inmunologia, Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, Ciudad Universitaria, Mexico City, Mexico
    Immunol Cell Biol 90:137-48. 2012
    ..The purpose of this review is to highlight the versatile nature of activins/inhibins as key regulators of both the innate and adaptive immune responses...
  11. doi request reprint CD11c decrease in mouse thymic dendritic cells after vanadium inhalation
    M Ustarroz-Cano
    Departamento de Biologia Celular y Tisular, Universidad Nacional Autonoma de Mexico, Mexico City, Mexico
    J Immunotoxicol 9:374-80. 2012
    ..Such an outcome could, in turn, increase the risk for development of autoimmune reactions in different organs specifically, and of autoimmune diseases in general in these V-exposed hosts...
  12. doi request reprint Increased numbers of thymic and peripheral CD4+ CD25+Foxp3+ cells in the absence of CD5 signaling
    Diana Ordoñez-Rueda
    Departamento de Inmunologia, Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, Distrito Federal, Mexico
    Eur J Immunol 39:2233-47. 2009
    ..Furthermore, we provide new evidence supporting a potential role of CD5 in thymocyte survival, through a mechanism that may involve the phosphorylation of Akt...
  13. ncbi request reprint The role of TGF-beta superfamily during T cell development: new insights
    P Licona-Limón
    Department of Immunology, Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, Circuito Escolar s n, Mexico DF 04510, Mexico
    Immunol Lett 109:1-12. 2007
    ..This review provides new insights on the function of members of the TGF-beta superfamily at different stages of thymocyte development...
  14. doi request reprint CCR9+ T cells contribute to the resolution of the inflammatory response in a mouse model of intestinal amoebiasis
    A E Rojas-López
    CBRL, Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, Mexico
    Immunobiology 217:795-807. 2012
    ..Our data suggest that a population of CCR9(+)CD4(+)CD25(+)FoxP3(+) T cells may participate in the control and resolution of the inflammatory immune response to E. histolytica infection...
  15. pmc CDIP-2, a synthetic peptide derived from chemokine (C-C motif) ligand 13 (CCL13), ameliorates allergic airway inflammation
    E Mendez-Enriquez
    Departamento de Inmunologia, Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, Mexico
    Clin Exp Immunol 152:354-63. 2008
    ..Thus, CDIP-2 may be considered as part of a novel group of anti-inflammatory agents based on chemokine-derived synthetic peptides...
  16. ncbi request reprint Entamoeba histolytica cysteine protease 2 (EhCP2) modulates leucocyte migration by proteolytic cleavage of chemokines
    S Pertuz Belloso
    Department of Immunology, Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, DF, Mexico
    Parasite Immunol 26:237-41. 2004
    ..Thus, the extracellular activity of the cysteine proteases affects chemokine-mediated responses and could be considered as part of the mechanisms used by Entamoeba histolytica to circumvent the host immune responses...
  17. pmc Jak3 is involved in dendritic cell maturation and CCR7-dependent migration
    Ana Rivas-Caicedo
    Departamento de Inmunologia, Instituto de Investigaciones Biomedicas, Mexico, DF, Mexico
    PLoS ONE 4:e7066. 2009
    ..CCR7-mediated signalling is important for dendritic cell maturation and homing to the lymph nodes. We have previously demonstrated that Jak3 participates in the signalling pathway of CCR7 in T lymphocytes...
  18. ncbi request reprint Inhibins are the major activin ligands expressed during early thymocyte development
    Paula Licona
    Departamento de Inmunologia, Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, Circuito Escolar s n, Mexico DF 04510
    Dev Dyn 235:1124-32. 2006
    ..Our data indicate that Activin/Inhibin signaling could regulate the process of thymus organogenesis and early thymocyte differentiation, as it has been demonstrated for other members of the TGF-beta superfamily...
  19. ncbi request reprint Analysis of the antimicrobial activities of a chemokine-derived peptide (CDAP-4) on Pseudomonas aeruginosa
    Francisco Martínez-Becerra
    Department of Immunology, Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, Circuito Escolar s n, Mexico, DF, CP 04510, Mexico
    Biochem Biophys Res Commun 355:352-8. 2007
    ..Furthermore, CDAP-4 could be considered a good antimicrobial candidate with a potential use against pathogens including P. aeruginosa...
  20. doi request reprint A specific signalling signature characterizes the development of naturally occurring and antigen-specific regulatory T cells
    Karen Nava
    Departamento de Inmunología Instituto de Investigaciones Biomédicas, Universidad Nacional Autonoma de Mexico, Distrito Federal, Mexico
    Immunol Invest 38:851-67. 2009
    ..We conclude that thymus-derived Tregs display a characteristic "signalling signature" that suggests qualitative differences in TCR-mediated signalling that may not be explained merely by a higher TCR avidity...
  21. ncbi request reprint Effect of pro-inflammatory cytokine stimulation on human breast cancer: implications of chemokine receptor expression in cancer metastasis
    Julio E Valdivia-Silva
    Departamento de Inmunologia, Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, Ciudad Universitaria, Circuito exterior s n, C P 04510 DF, Mexico
    Cancer Lett 283:176-85. 2009
    ..Interestingly, this regulation was not homogeneous, emphasizing the inherent heterogeneity in cancer that may be responsive to specific inflammatory microenvironments...
  22. ncbi request reprint CD16+ human monocyte-derived dendritic cells matured with different and unrelated stimuli promote similar allogeneic Th2 responses: regulation by pro- and anti-inflammatory cytokines
    Amaranta Rivas-Carvalho
    Department of Molecular Biomedicine, Centro de Investigacion y de Estudios Avanzados IPN, Instituto de Investigaciones Biomedicas, UNAM, Mexico City, Mexico
    Int Immunol 16:1251-63. 2004
    ..These results indicate that 16+mDC elicit superior Th2 responses independently of the maturation factors that they received, and suggest that they could represent an important population of regulatory DC...