Maria Sitges

Summary

Country: Mexico

Publications

  1. doi request reprint The antidepressant sertraline prevents the behavioral and EEG changes induced in two animal models of seizures
    Maria Sitges
    Depto de Biología Celular y Fisiología, Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, Mexico
    Epilepsy Behav 25:511-6. 2012
  2. doi request reprint Vinpocetine inhibits glutamate release induced by the convulsive agent 4-aminopyridine more potently than several antiepileptic drugs
    M Sitges
    Departamento de Biologia Celular y Fisiologia, Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, A P 70228, Ciudad Universitaria, 04510 Mexico City, Mexico
    Epilepsy Res 96:257-66. 2011
  3. doi request reprint Characterization of phenytoin, carbamazepine, vinpocetine and clorgyline simultaneous effects on sodium channels and catecholamine metabolism in rat striatal nerve endings
    Maria Sitges
    Depto de Biología Celular y Fisiología, Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, Apartado Postal 70228, Ciudad Universitaria, 04510 Mexico, D F, Mexico
    Neurochem Res 34:470-9. 2009
  4. ncbi request reprint Effects of carbamazepine, phenytoin, valproic acid, oxcarbazepine, lamotrigine, topiramate and vinpocetine on the presynaptic Ca2+ channel-mediated release of [3H]glutamate: comparison with the Na+ channel-mediated release
    Maria Sitges
    Departamento de Biologia Celular y Fisiologia, Instituto de Investigaciones Biomedicas, UNAM, Apartado Postal 70228, Ciudad Universitaria 04510, Mexico D F, Mexico
    Neuropharmacology 53:854-62. 2007
  5. ncbi request reprint Acute and chronic effects of carbamazepine, phenytoin, valproate and vinpocetine on BAEP parameters and threshold in the guinea pig
    Maria Sitges
    Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, Mexico
    Clin Neurophysiol 118:420-6. 2007
  6. ncbi request reprint Effects of carbamazepine, phenytoin, lamotrigine, oxcarbazepine, topiramate and vinpocetine on Na+ channel-mediated release of [3H]glutamate in hippocampal nerve endings
    Maria Sitges
    Departamento de Biologia Celular y Fisiologia, Instituto de Investigaciones Biomedicas, UNAM, Apartado Postal 70228, Ciudad Universitaria 04510, Mexico D F, Mexico
    Neuropharmacology 52:598-605. 2007
  7. ncbi request reprint Single and combined effects of carbamazepine and vinpocetine on depolarization-induced changes in Na+, Ca2+ and glutamate release in hippocampal isolated nerve endings
    Maria Sitges
    Depto de Biología Celular y Fisiología, Instituto de Investigaciones Biomedicas, UNAM, Apartado Postal 70228, Ciudad Univeresitaria, 04510 Mexico D F, Mexico
    Neurochem Int 49:55-61. 2006
  8. ncbi request reprint Vinpocetine blockade of sodium channels inhibits the rise in sodium and calcium induced by 4-aminopyridine in synaptosomes
    Maria Sitges
    Departmento de Biologia Celular y Fisiologia, Instituto de Investigaciones Biomedicas, UNAM, Apartado Postal 70228, Ciudad Universitaria 04510, Mexico, D F, Mexico
    Neurochem Int 46:533-40. 2005
  9. ncbi request reprint Characterization of the participation of sodium channels on the rise in Na+ induced by 4-aminopyridine (4-AP) in synaptosomes
    Emilio Galván
    Departmento de Biologia Celular y Fisiologia, Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, Mexico City, Mexico
    Neurochem Res 29:347-55. 2004
  10. doi request reprint Sertraline inhibits pre-synaptic Na⁺ channel-mediated responses in hippocampus-isolated nerve endings
    Blanca I Aldana
    Departamento de Biologia Celular y Fisiologia, Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, Ciudad Universitaria, Mexico D F, Mexico
    J Neurochem 121:197-205. 2012

Collaborators

  • Nieves Herrera-Mundo
  • Blanca I Aldana
  • Emilio Galván

Detail Information

Publications14

  1. doi request reprint The antidepressant sertraline prevents the behavioral and EEG changes induced in two animal models of seizures
    Maria Sitges
    Depto de Biología Celular y Fisiología, Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, Mexico
    Epilepsy Behav 25:511-6. 2012
    ..Moreover, a single carbamazepine dose of 25 mg/kg (i.p.), but not of 15 mg/kg, prevented the changes induced by the above convulsive agents. An anti-seizure action of the antidepressant sertraline is strongly suggested by these findings...
  2. doi request reprint Vinpocetine inhibits glutamate release induced by the convulsive agent 4-aminopyridine more potently than several antiepileptic drugs
    M Sitges
    Departamento de Biologia Celular y Fisiologia, Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, A P 70228, Ciudad Universitaria, 04510 Mexico City, Mexico
    Epilepsy Res 96:257-66. 2011
    ....
  3. doi request reprint Characterization of phenytoin, carbamazepine, vinpocetine and clorgyline simultaneous effects on sodium channels and catecholamine metabolism in rat striatal nerve endings
    Maria Sitges
    Depto de Biología Celular y Fisiología, Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, Apartado Postal 70228, Ciudad Universitaria, 04510 Mexico, D F, Mexico
    Neurochem Res 34:470-9. 2009
    ....
  4. ncbi request reprint Effects of carbamazepine, phenytoin, valproic acid, oxcarbazepine, lamotrigine, topiramate and vinpocetine on the presynaptic Ca2+ channel-mediated release of [3H]glutamate: comparison with the Na+ channel-mediated release
    Maria Sitges
    Departamento de Biologia Celular y Fisiologia, Instituto de Investigaciones Biomedicas, UNAM, Apartado Postal 70228, Ciudad Universitaria 04510, Mexico D F, Mexico
    Neuropharmacology 53:854-62. 2007
    ....
  5. ncbi request reprint Acute and chronic effects of carbamazepine, phenytoin, valproate and vinpocetine on BAEP parameters and threshold in the guinea pig
    Maria Sitges
    Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, Mexico
    Clin Neurophysiol 118:420-6. 2007
    ....
  6. ncbi request reprint Effects of carbamazepine, phenytoin, lamotrigine, oxcarbazepine, topiramate and vinpocetine on Na+ channel-mediated release of [3H]glutamate in hippocampal nerve endings
    Maria Sitges
    Departamento de Biologia Celular y Fisiologia, Instituto de Investigaciones Biomedicas, UNAM, Apartado Postal 70228, Ciudad Universitaria 04510, Mexico D F, Mexico
    Neuropharmacology 52:598-605. 2007
    ..Considering that the high doses of antiepileptic drugs required to control seizures are frequently accompanied by adverse secondary effects, the higher potency of vinpocetine to reduce Na(+) channels permeability might be advantageous...
  7. ncbi request reprint Single and combined effects of carbamazepine and vinpocetine on depolarization-induced changes in Na+, Ca2+ and glutamate release in hippocampal isolated nerve endings
    Maria Sitges
    Depto de Biología Celular y Fisiología, Instituto de Investigaciones Biomedicas, UNAM, Apartado Postal 70228, Ciudad Univeresitaria, 04510 Mexico D F, Mexico
    Neurochem Int 49:55-61. 2006
    ....
  8. ncbi request reprint Vinpocetine blockade of sodium channels inhibits the rise in sodium and calcium induced by 4-aminopyridine in synaptosomes
    Maria Sitges
    Departmento de Biologia Celular y Fisiologia, Instituto de Investigaciones Biomedicas, UNAM, Apartado Postal 70228, Ciudad Universitaria 04510, Mexico, D F, Mexico
    Neurochem Int 46:533-40. 2005
    ..The inhibitory effect of vinpocetine on pre-synaptic voltage-sensitive sodium channels may underlie the in vivo anticonvulsant action of vinpocetine...
  9. ncbi request reprint Characterization of the participation of sodium channels on the rise in Na+ induced by 4-aminopyridine (4-AP) in synaptosomes
    Emilio Galván
    Departmento de Biologia Celular y Fisiologia, Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, Mexico City, Mexico
    Neurochem Res 29:347-55. 2004
    ....
  10. doi request reprint Sertraline inhibits pre-synaptic Na⁺ channel-mediated responses in hippocampus-isolated nerve endings
    Blanca I Aldana
    Departamento de Biologia Celular y Fisiologia, Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, Ciudad Universitaria, Mexico D F, Mexico
    J Neurochem 121:197-205. 2012
    ..In summary, present findings demonstrate that besides the inhibition of 5-HT reuptake, sertraline is an effective inhibitor of pre-synaptic Na(+) channels controlling neurotransmitter release...
  11. doi request reprint Vinpocetine and α-tocopherol prevent the increase in DA and oxidative stress induced by 3-NPA in striatum isolated nerve endings
    Nieves Herrera-Mundo
    Departamento de Biologia Celular y Fisiologia, Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, Mexico
    J Neurochem 124:233-40. 2013
    ....
  12. ncbi request reprint Omega-agatoxin-TK is a useful tool to study P-type Ca2+ channel-mediated changes in internal Ca2+ and glutamate release in depolarised brain nerve terminals
    Maria Sitges
    Departmento de Biologia Celular y Fisiologia, Instituto de Investigaciones Biomedicas, Apartado Postal 70228, Ciudad Universitaria 04510, Mexico, DF
    Neurochem Int 46:53-60. 2005
    ..These results indicate that omega-agatoxin-TK represents a good pharmacological tool to study P/Q type Ca(2+) channel-mediated responses in cerebral nerve endings...
  13. ncbi request reprint Vinpocetine prevents 4-aminopyridine-induced changes in the EEG, the auditory brainstem responses and hearing
    Maria Sitges
    Depto de Biología Celular y Fisiología, Instituto de Investigaciones Biomedicas, UNAM, Apartado Postal 70228, Ciudad Universitaria 04510, Mexico City, DF, Mexico
    Clin Neurophysiol 115:2711-7. 2004
    ....
  14. doi request reprint Mechanisms underlying striatal vulnerability to 3-nitropropionic acid
    Nieves Herrera-Mundo
    Departamento de Biologia Celular y Fisiologia, Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, Mexico DF, Mexico
    J Neurochem 114:597-605. 2010
    ....