Maria Sitges

Summary

Country: Mexico

Publications

  1. ncbi Effects of external pH variations on brain presynaptic sodium and calcium channels; repercussion on the evoked release of amino acid neurotransmitters
    M Sitges
    Depto de Biologia Celular, Instituto de Investigaciones Biomedicas, UNAM, Mexico, DF
    Neurochem Res 23:477-85. 1998
  2. ncbi Study on the possible involvement of protein kinases in the modulation of brain presynaptic sodium channels; comparison with calcium channels
    M Sitges
    Depto de Biologia Celular, Instituto de Investigaciones Biomedicas, Mexico, Mexico
    Neurochem Int 32:177-90. 1998
  3. ncbi Chronic verapamil modifies striatal and frontal cortex dopamine levels
    M Sitges
    Depto de Biologia Celular, Instituto de Investigaciones Biomedicas, Ciudad Universitaria, Mexico, Mexico DF
    Eur Neuropsychopharmacol 8:105-11. 1998
  4. ncbi Vinpocetine selectively inhibits neurotransmitter release triggered by sodium channel activation
    M Sitges
    Depto de Biologia Celular, Instituto de Investigaciones Biomedicas, UNAM, Ciudad Universitaria, Mexico
    Neurochem Res 24:1585-91. 1999
  5. ncbi Simultaneous action of MK-801 (dizclopine) on dopamine, glutamate, aspartate and GABA release from striatum isolated nerve endings
    M Sitges
    Depto de Biologia Celular, Instituto de Investigaciones Biomedicas, UNAM, Mexico, DF, Mexico
    Brain Res 854:48-56. 2000
  6. ncbi Vinpocetine prevents 4-aminopyridine-induced changes in the EEG, the auditory brainstem responses and hearing
    Maria Sitges
    Depto de Biología Celular y Fisiología, Instituto de Investigaciones Biomedicas, UNAM, Apartado Postal 70228, Ciudad Universitaria 04510, Mexico City, DF, Mexico
    Clin Neurophysiol 115:2711-7. 2004
  7. ncbi Vinpocetine blockade of sodium channels inhibits the rise in sodium and calcium induced by 4-aminopyridine in synaptosomes
    Maria Sitges
    Departmento de Biologia Celular y Fisiologia, Instituto de Investigaciones Biomedicas, UNAM, Apartado Postal 70228, Ciudad Universitaria 04510, Mexico, D F, Mexico
    Neurochem Int 46:533-40. 2005
  8. ncbi Characterization of the participation of sodium channels on the rise in Na+ induced by 4-aminopyridine (4-AP) in synaptosomes
    Emilio Galván
    Departmento de Biologia Celular y Fisiologia, Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, Mexico City, Mexico
    Neurochem Res 29:347-55. 2004
  9. doi Sertraline inhibits pre-synaptic Na⁺ channel-mediated responses in hippocampus-isolated nerve endings
    Blanca I Aldana
    Departamento de Biologia Celular y Fisiologia, Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, Ciudad Universitaria, Mexico D F, Mexico
    J Neurochem 121:197-205. 2012
  10. ncbi Effects of carbamazepine, phenytoin, valproic acid, oxcarbazepine, lamotrigine, topiramate and vinpocetine on the presynaptic Ca2+ channel-mediated release of [3H]glutamate: comparison with the Na+ channel-mediated release
    Maria Sitges
    Departamento de Biologia Celular y Fisiologia, Instituto de Investigaciones Biomedicas, UNAM, Apartado Postal 70228, Ciudad Universitaria 04510, Mexico D F, Mexico
    Neuropharmacology 53:854-62. 2007

Collaborators

  • F Pena
  • Nieves Herrera-Mundo
  • Blanca I Aldana
  • Emilio Galván
  • Vladimir Nekrassov

Detail Information

Publications19

  1. ncbi Effects of external pH variations on brain presynaptic sodium and calcium channels; repercussion on the evoked release of amino acid neurotransmitters
    M Sitges
    Depto de Biologia Celular, Instituto de Investigaciones Biomedicas, UNAM, Mexico, DF
    Neurochem Res 23:477-85. 1998
    ..It is concluded that external H+ regulate amino acid neurotransmitter release by their actions on presynaptic Na+ channels, as well as on presynaptic Ca2+ channels...
  2. ncbi Study on the possible involvement of protein kinases in the modulation of brain presynaptic sodium channels; comparison with calcium channels
    M Sitges
    Depto de Biologia Celular, Instituto de Investigaciones Biomedicas, Mexico, Mexico
    Neurochem Int 32:177-90. 1998
    ..On the other hand, while Ca2+ and calmodulin dependent protein kinase II is unable to modulate brain presynaptic voltage sensitive Na+ channels, it facilitates the activation of brain presynaptic voltage sensitive Ca2+ channels...
  3. ncbi Chronic verapamil modifies striatal and frontal cortex dopamine levels
    M Sitges
    Depto de Biologia Celular, Instituto de Investigaciones Biomedicas, Ciudad Universitaria, Mexico, Mexico DF
    Eur Neuropsychopharmacol 8:105-11. 1998
    ..We conclude that DA autoreceptors are implicated in verapamil's effects on frontal cortex and striatum DA levels; and that the presumed antimanic action exerted by verapamil is due to its long-term effect on these receptors...
  4. ncbi Vinpocetine selectively inhibits neurotransmitter release triggered by sodium channel activation
    M Sitges
    Depto de Biologia Celular, Instituto de Investigaciones Biomedicas, UNAM, Ciudad Universitaria, Mexico
    Neurochem Res 24:1585-91. 1999
    ....
  5. ncbi Simultaneous action of MK-801 (dizclopine) on dopamine, glutamate, aspartate and GABA release from striatum isolated nerve endings
    M Sitges
    Depto de Biologia Celular, Instituto de Investigaciones Biomedicas, UNAM, Mexico, DF, Mexico
    Brain Res 854:48-56. 2000
    ....
  6. ncbi Vinpocetine prevents 4-aminopyridine-induced changes in the EEG, the auditory brainstem responses and hearing
    Maria Sitges
    Depto de Biología Celular y Fisiología, Instituto de Investigaciones Biomedicas, UNAM, Apartado Postal 70228, Ciudad Universitaria 04510, Mexico City, DF, Mexico
    Clin Neurophysiol 115:2711-7. 2004
    ....
  7. ncbi Vinpocetine blockade of sodium channels inhibits the rise in sodium and calcium induced by 4-aminopyridine in synaptosomes
    Maria Sitges
    Departmento de Biologia Celular y Fisiologia, Instituto de Investigaciones Biomedicas, UNAM, Apartado Postal 70228, Ciudad Universitaria 04510, Mexico, D F, Mexico
    Neurochem Int 46:533-40. 2005
    ..The inhibitory effect of vinpocetine on pre-synaptic voltage-sensitive sodium channels may underlie the in vivo anticonvulsant action of vinpocetine...
  8. ncbi Characterization of the participation of sodium channels on the rise in Na+ induced by 4-aminopyridine (4-AP) in synaptosomes
    Emilio Galván
    Departmento de Biologia Celular y Fisiologia, Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, Mexico City, Mexico
    Neurochem Res 29:347-55. 2004
    ....
  9. doi Sertraline inhibits pre-synaptic Na⁺ channel-mediated responses in hippocampus-isolated nerve endings
    Blanca I Aldana
    Departamento de Biologia Celular y Fisiologia, Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, Ciudad Universitaria, Mexico D F, Mexico
    J Neurochem 121:197-205. 2012
    ..In summary, present findings demonstrate that besides the inhibition of 5-HT reuptake, sertraline is an effective inhibitor of pre-synaptic Na(+) channels controlling neurotransmitter release...
  10. ncbi Effects of carbamazepine, phenytoin, valproic acid, oxcarbazepine, lamotrigine, topiramate and vinpocetine on the presynaptic Ca2+ channel-mediated release of [3H]glutamate: comparison with the Na+ channel-mediated release
    Maria Sitges
    Departamento de Biologia Celular y Fisiologia, Instituto de Investigaciones Biomedicas, UNAM, Apartado Postal 70228, Ciudad Universitaria 04510, Mexico D F, Mexico
    Neuropharmacology 53:854-62. 2007
    ....
  11. doi Characterization of phenytoin, carbamazepine, vinpocetine and clorgyline simultaneous effects on sodium channels and catecholamine metabolism in rat striatal nerve endings
    Maria Sitges
    Depto de Biología Celular y Fisiología, Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, Apartado Postal 70228, Ciudad Universitaria, 04510 Mexico, D F, Mexico
    Neurochem Res 34:470-9. 2009
    ....
  12. doi Vinpocetine and α-tocopherol prevent the increase in DA and oxidative stress induced by 3-NPA in striatum isolated nerve endings
    Nieves Herrera-Mundo
    Departamento de Biologia Celular y Fisiologia, Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, Mexico
    J Neurochem 124:233-40. 2013
    ....
  13. ncbi Single and combined effects of carbamazepine and vinpocetine on depolarization-induced changes in Na+, Ca2+ and glutamate release in hippocampal isolated nerve endings
    Maria Sitges
    Depto de Biología Celular y Fisiología, Instituto de Investigaciones Biomedicas, UNAM, Apartado Postal 70228, Ciudad Univeresitaria, 04510 Mexico D F, Mexico
    Neurochem Int 49:55-61. 2006
    ....
  14. ncbi Effects of pentylenetetrazole and 4-aminopyridine on the auditory brainstem response (ABR) and on the hearing sensitivity in the guinea pig in vivo
    Vladimir Nekrassov
    Instituto Nacional de la Comunicación Humana, CNR, SSA, PDCBS, UAM, Mexico, D F, Mexico
    Epilepsy Res 53:245-54. 2003
    ..These data indicate that changes in the activity of the lateral and the medial nuclei of the superior olivary complex (SOC) accompany the hearing loss and the post-ictal epileptic cortical activity...
  15. ncbi Omega-agatoxin-TK is a useful tool to study P-type Ca2+ channel-mediated changes in internal Ca2+ and glutamate release in depolarised brain nerve terminals
    Maria Sitges
    Departmento de Biologia Celular y Fisiologia, Instituto de Investigaciones Biomedicas, Apartado Postal 70228, Ciudad Universitaria 04510, Mexico, DF
    Neurochem Int 46:53-60. 2005
    ..These results indicate that omega-agatoxin-TK represents a good pharmacological tool to study P/Q type Ca(2+) channel-mediated responses in cerebral nerve endings...
  16. ncbi Effects of carbamazepine, phenytoin, lamotrigine, oxcarbazepine, topiramate and vinpocetine on Na+ channel-mediated release of [3H]glutamate in hippocampal nerve endings
    Maria Sitges
    Departamento de Biologia Celular y Fisiologia, Instituto de Investigaciones Biomedicas, UNAM, Apartado Postal 70228, Ciudad Universitaria 04510, Mexico D F, Mexico
    Neuropharmacology 52:598-605. 2007
    ..Considering that the high doses of antiepileptic drugs required to control seizures are frequently accompanied by adverse secondary effects, the higher potency of vinpocetine to reduce Na(+) channels permeability might be advantageous...
  17. doi The antidepressant sertraline prevents the behavioral and EEG changes induced in two animal models of seizures
    Maria Sitges
    Depto de Biología Celular y Fisiología, Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, Mexico
    Epilepsy Behav 25:511-6. 2012
    ..Moreover, a single carbamazepine dose of 25 mg/kg (i.p.), but not of 15 mg/kg, prevented the changes induced by the above convulsive agents. An anti-seizure action of the antidepressant sertraline is strongly suggested by these findings...
  18. ncbi Acute and chronic effects of carbamazepine, phenytoin, valproate and vinpocetine on BAEP parameters and threshold in the guinea pig
    Maria Sitges
    Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, Mexico
    Clin Neurophysiol 118:420-6. 2007
    ....
  19. doi Mechanisms underlying striatal vulnerability to 3-nitropropionic acid
    Nieves Herrera-Mundo
    Departamento de Biologia Celular y Fisiologia, Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, Mexico DF, Mexico
    J Neurochem 114:597-605. 2010
    ....