Xochitl Perez-Martinez

Summary

Country: Mexico

Publications

  1. ncbi request reprint Protein synthesis and assembly in mitochondrial disorders
    Xochitl Perez-Martinez
    Departamento de Bioquimica, Instituto de Fisiologia Celular, Universidad Nacional Autonoma de Mexico, Mexico
    Curr Top Med Chem 8:1335-50. 2008
  2. pmc The carboxyl-terminal end of Cox1 is required for feedback assembly regulation of Cox1 synthesis in Saccharomyces cerevisiae mitochondria
    Miguel Shingú-Vázquez
    Departamento de Genetica Molecular, Instituto de Fisiologia Celular, Universidad Nacional Autonoma de Mexico, Mexico DF 04510, Mexico
    J Biol Chem 285:34382-9. 2010
  3. pmc Dual functions of Mss51 couple synthesis of Cox1 to assembly of cytochrome c oxidase in Saccharomyces cerevisiae mitochondria
    Xochitl Perez-Martinez
    Departamento de Bioquimica, Instituto de Fisiologia Celular, Universidad Nacional Autonoma de Mexico, Mexico D F 04510, Mexico
    Mol Biol Cell 20:4371-80. 2009
  4. ncbi request reprint Structure of nuclear-localized cox3 genes in Chlamydomonas reinhardtii and in its colorless close relative Polytomella sp
    Xochitl Perez-Martinez
    Departamento de Genetica Molecular, Instituto de Fisiologia Celular, Universidad Nacional Autonoma de Mexico, Apartado Postal 70 243, 04510, D F, Mexico
    Curr Genet 40:399-404. 2002
  5. doi request reprint The cytosol-synthesized subunit II (Cox2) precursor with the point mutation W56R is correctly processed in yeast mitochondria to rescue cytochrome oxidase
    Valentín Cruz-Torres
    Instituto de Fisiologia Celular, Universidad Nacional Autonoma de Mexico, Mexico D F, Mexico
    Biochim Biophys Acta 1817:2128-39. 2012
  6. ncbi request reprint Genetic correction of mitochondrial diseases: using the natural migration of mitochondrial genes to the nucleus in chlorophyte algae as a model system
    Diego González-Halphen
    Departamento de Genetica Molecular, Instituto de Fisiologia Celular, Universidad Nacional Autonoma de Mexico, 04510 Mexico D F, Mexico
    Ann N Y Acad Sci 1019:232-9. 2004
  7. ncbi request reprint The pentatricopeptide repeats present in Pet309 are necessary for translation but not for stability of the mitochondrial COX1 mRNA in yeast
    Faviola Tavares-Carreón
    Departamento de Bioquimica, Instituto de Fisiologia Celular, Universidad Nacional Autonoma de Mexico, Circuito exterior s n, Ciudad Universitaria, Apartado Postal 70 243, Mexico City 04510, Mexico
    J Biol Chem 283:1472-9. 2008
  8. doi request reprint In Saccharomyces cerevisiae, the phosphate carrier is a component of the mitochondrial unselective channel
    Manuel Gutiérrez-Aguilar
    Depto de Bioquimica, Instituto de Fisiologia Celular, UNAM, Mexico City, Mexico
    Arch Biochem Biophys 494:184-91. 2010

Collaborators

  • Edmundo Chávez
  • Miguel Shingú-Vázquez
  • Diego González-Halphen
  • Valentín Cruz-Torres
  • Manuel Gutiérrez-Aguilar
  • Yolanda Camacho-Villasana
  • Faviola Tavares-Carreón
  • Rodolfo García-Villegas
  • Miriam Vázquez-Acevedo
  • Guillermo Mendoza-Hernandez
  • Thomas D Fox
  • Christine A Butler
  • Salvador Uribe-Carvajal
  • Luisa Sandoval-Romero
  • Alfredo Torres-Larios
  • Angélica Zamudio-Ochoa
  • M Gonzalo Claros
  • Edgar Davidson
  • Michael P King
  • Soledad Funes
  • Adrian Reyes-Prieto

Detail Information

Publications8

  1. ncbi request reprint Protein synthesis and assembly in mitochondrial disorders
    Xochitl Perez-Martinez
    Departamento de Bioquimica, Instituto de Fisiologia Celular, Universidad Nacional Autonoma de Mexico, Mexico
    Curr Top Med Chem 8:1335-50. 2008
    ..In the present review we will discuss the most recent advances in the understanding of the mechanisms and factors that govern mammalian mitochondrial translation/protein insertion, as well as known pathologies associated with them...
  2. pmc The carboxyl-terminal end of Cox1 is required for feedback assembly regulation of Cox1 synthesis in Saccharomyces cerevisiae mitochondria
    Miguel Shingú-Vázquez
    Departamento de Genetica Molecular, Instituto de Fisiologia Celular, Universidad Nacional Autonoma de Mexico, Mexico DF 04510, Mexico
    J Biol Chem 285:34382-9. 2010
    ..Our data suggest a novel activity of Pet54 required for normal synthesis of Cox1 that is independent of the Cox1 C-terminal end...
  3. pmc Dual functions of Mss51 couple synthesis of Cox1 to assembly of cytochrome c oxidase in Saccharomyces cerevisiae mitochondria
    Xochitl Perez-Martinez
    Departamento de Bioquimica, Instituto de Fisiologia Celular, Universidad Nacional Autonoma de Mexico, Mexico D F 04510, Mexico
    Mol Biol Cell 20:4371-80. 2009
    ..Regulation of COX1 mRNA translation by Mss51 seems to be an example of a homeostatic mechanism in which a positive effector of gene expression interacts with the product it regulates in a posttranslational assembly process...
  4. ncbi request reprint Structure of nuclear-localized cox3 genes in Chlamydomonas reinhardtii and in its colorless close relative Polytomella sp
    Xochitl Perez-Martinez
    Departamento de Genetica Molecular, Instituto de Fisiologia Celular, Universidad Nacional Autonoma de Mexico, Apartado Postal 70 243, 04510, D F, Mexico
    Curr Genet 40:399-404. 2002
    ..reinhardtii after the cox3 gene was transferred to the nucleus. The data also support the evolutionary hypothesis of a recent acquisition of introns in C. reinhardtii...
  5. doi request reprint The cytosol-synthesized subunit II (Cox2) precursor with the point mutation W56R is correctly processed in yeast mitochondria to rescue cytochrome oxidase
    Valentín Cruz-Torres
    Instituto de Fisiologia Celular, Universidad Nacional Autonoma de Mexico, Mexico D F, Mexico
    Biochim Biophys Acta 1817:2128-39. 2012
    ..Still, the allotopically-expressed Cox2(W56R) restores CcO activity and allows mitochondrial Cox1 synthesis to advance at WT levels...
  6. ncbi request reprint Genetic correction of mitochondrial diseases: using the natural migration of mitochondrial genes to the nucleus in chlorophyte algae as a model system
    Diego González-Halphen
    Departamento de Genetica Molecular, Instituto de Fisiologia Celular, Universidad Nacional Autonoma de Mexico, 04510 Mexico D F, Mexico
    Ann N Y Acad Sci 1019:232-9. 2004
    ..Information derived from these studies should be applicable toward the development of genetic therapies for human diseases resulting from mutations in mtDNA-encoded polypeptides...
  7. ncbi request reprint The pentatricopeptide repeats present in Pet309 are necessary for translation but not for stability of the mitochondrial COX1 mRNA in yeast
    Faviola Tavares-Carreón
    Departamento de Bioquimica, Instituto de Fisiologia Celular, Universidad Nacional Autonoma de Mexico, Circuito exterior s n, Ciudad Universitaria, Apartado Postal 70 243, Mexico City 04510, Mexico
    J Biol Chem 283:1472-9. 2008
    ..Our results show that the RNA metabolism function of Pet309 is found in at least two separate domains of the protein...
  8. doi request reprint In Saccharomyces cerevisiae, the phosphate carrier is a component of the mitochondrial unselective channel
    Manuel Gutiérrez-Aguilar
    Depto de Bioquimica, Instituto de Fisiologia Celular, UNAM, Mexico City, Mexico
    Arch Biochem Biophys 494:184-91. 2010
    ..1 kDa PEG evidenced a higher sensitivity in mitochondria from the mutant strain. The above data suggest that the phosphate carrier is the phosphate sensor in YMUC and contributes to the structure of this channel...