C F Arias

Summary

Country: Mexico

Publications

  1. pmc Characterization of viroplasm formation during the early stages of rotavirus infection
    José J Carreño-Torres
    Departamento de Genética del Desarrollo y Fisiología Molecular, Instituto de Biotecnologia, Universidad Nacional Autonoma de Mexico
    Virol J 7:350. 2010
  2. pmc Comparative study of enteric viruses, coliphages and indicator bacteria for evaluating water quality in a tropical high-altitude system
    Ana C Espinosa
    Instituto de Ecologia, Universidad Nacional Autonoma de Mexico, Circuito Exterior, Ciudad Universitaria, Coyoacan, 04510 Mexico, DF, Mexico
    Environ Health 8:49. 2009
  3. ncbi request reprint Molecular biology of rotavirus cell entry
    Carlos F Arias
    Departamento de Genetica y Fisiologia Molecular, Instituto de Biotecnologia, Universidad Nacional Autonoma de Mexico, Cuernavaca, Morelos, Mexico
    Arch Med Res 33:356-61. 2002
  4. pmc Trypsin activation pathway of rotavirus infectivity
    C F Arias
    Departamento de Genetica y Fisiologia Molecular, Universidad Nacional Autonoma de Mexico, Cuernavaca, Morelos, Mexico
    J Virol 70:5832-9. 1996
  5. doi request reprint Molecular anatomy of 2009 influenza virus A (H1N1)
    Carlos F Arias
    Instituto de Biotecnologia, Universidad Nacional Autonoma de Mexico, Cuernavaca, Morelos, Mexico
    Arch Med Res 40:643-54. 2009
  6. ncbi request reprint Characterization of a monoclonal antibody directed to the surface of MA104 cells that blocks the infectivity of rotaviruses
    S Lopez
    Departamento de Genetica y Fisiologia Molecular, Instituto de Biotecnologia
    Virology 273:160-8. 2000
  7. pmc Silencing the morphogenesis of rotavirus
    Tomàs López
    Departamento de Genética del Desarrollo y Fisiología Molecular, Instituto de Biotecnologia, Universidad Nacional Autonoma de Mexico, Cuernavaca, Morelos, Mexico
    J Virol 79:184-92. 2005
  8. pmc The amino-terminal half of rotavirus SA114fM VP4 protein contains a hemagglutination domain and primes for neutralizing antibodies to the virus
    M Lizano
    Departamento de Biologia Molecular, Universidad Nacional Autonoma de Mexico, Cuernavaca, Morelos
    J Virol 65:1383-91. 1991
  9. pmc Functional and structural analysis of the sialic acid-binding domain of rotaviruses
    P Isa
    Departamento de Genetica y Fisiologia Molecular, Universidad Nacional Autonoma de Mexico, Cuernavaca, Morelos, Mexico
    J Virol 71:6749-56. 1997
  10. ncbi request reprint Early events of rotavirus infection: the search for the receptor(s)
    C F Arias
    , , , Cuernavaca, Morelos 62250, Mexico
    Novartis Found Symp 238:47-60; discussion 60-3. 2001

Collaborators

Detail Information

Publications44

  1. pmc Characterization of viroplasm formation during the early stages of rotavirus infection
    José J Carreño-Torres
    Departamento de Genética del Desarrollo y Fisiología Molecular, Instituto de Biotecnologia, Universidad Nacional Autonoma de Mexico
    Virol J 7:350. 2010
    ..The possibility that viroplasms formation is nucleated by the entering viral particles was investigated using fluorescently labeled purified rotavirus particles...
  2. pmc Comparative study of enteric viruses, coliphages and indicator bacteria for evaluating water quality in a tropical high-altitude system
    Ana C Espinosa
    Instituto de Ecologia, Universidad Nacional Autonoma de Mexico, Circuito Exterior, Ciudad Universitaria, Coyoacan, 04510 Mexico, DF, Mexico
    Environ Health 8:49. 2009
    ..Surface water from a tropical high-altitude system located in Mexico City that receives rainwater, treated and non-treated wastewater used for irrigation, and groundwater used for drinking, was studied...
  3. ncbi request reprint Molecular biology of rotavirus cell entry
    Carlos F Arias
    Departamento de Genetica y Fisiologia Molecular, Instituto de Biotecnologia, Universidad Nacional Autonoma de Mexico, Cuernavaca, Morelos, Mexico
    Arch Med Res 33:356-61. 2002
    ..We propose that the functional rotavirus receptor is a complex of several cell molecules most likely immersed in plasma membrane lipid microdomains...
  4. pmc Trypsin activation pathway of rotavirus infectivity
    C F Arias
    Departamento de Genetica y Fisiologia Molecular, Universidad Nacional Autonoma de Mexico, Cuernavaca, Morelos, Mexico
    J Virol 70:5832-9. 1996
    ..A pathway for the trypsin activation of rotavirus infectivity is proposed...
  5. doi request reprint Molecular anatomy of 2009 influenza virus A (H1N1)
    Carlos F Arias
    Instituto de Biotecnologia, Universidad Nacional Autonoma de Mexico, Cuernavaca, Morelos, Mexico
    Arch Med Res 40:643-54. 2009
    ....
  6. ncbi request reprint Characterization of a monoclonal antibody directed to the surface of MA104 cells that blocks the infectivity of rotaviruses
    S Lopez
    Departamento de Genetica y Fisiologia Molecular, Instituto de Biotecnologia
    Virology 273:160-8. 2000
    ..By a solid-phase immunoisolation technique, MAb 2D9 was found to react with three proteins of ca. 47, 55, and 220 kDa, which might form a complex...
  7. pmc Silencing the morphogenesis of rotavirus
    Tomàs López
    Departamento de Genética del Desarrollo y Fisiología Molecular, Instituto de Biotecnologia, Universidad Nacional Autonoma de Mexico, Cuernavaca, Morelos, Mexico
    J Virol 79:184-92. 2005
    ....
  8. pmc The amino-terminal half of rotavirus SA114fM VP4 protein contains a hemagglutination domain and primes for neutralizing antibodies to the virus
    M Lizano
    Departamento de Biologia Molecular, Universidad Nacional Autonoma de Mexico, Cuernavaca, Morelos
    J Virol 65:1383-91. 1991
    ..In addition, a single dose of the MS2-VP8' polypeptide was able to prime the immune system of mice for an augmented neutralizing antibody response when the animals were subsequently immunized with purified SA114fM virus...
  9. pmc Functional and structural analysis of the sialic acid-binding domain of rotaviruses
    P Isa
    Departamento de Genetica y Fisiologia Molecular, Universidad Nacional Autonoma de Mexico, Cuernavaca, Morelos, Mexico
    J Virol 71:6749-56. 1997
    ..The close proximity of these two loops is also supported by previous results from competition experiments with neutralizing MAbs directed at RRV VP8...
  10. ncbi request reprint Early events of rotavirus infection: the search for the receptor(s)
    C F Arias
    , , , Cuernavaca, Morelos 62250, Mexico
    Novartis Found Symp 238:47-60; discussion 60-3. 2001
    ..We propose that the functional rotavirus receptor is a complex of several cell molecules most likely immersed in glycosphingolipid-enriched plasma membrane microdomains...
  11. pmc Rotavirus Nonstructural Protein NSP3 is not required for viral protein synthesis
    Hilda Montero
    Instituto de Biotecnologia, UNAM, Avenida Universidad 2001, Colonia Chamilpa, Cuernavaca, Morelos 62210, Mexico
    J Virol 80:9031-8. 2006
    ..These results indicate that NSP3 is neither required for the translation of viral mRNAs nor essential for virus replication in cell culture...
  12. pmc Rotaviruses induce an early membrane permeabilization of MA104 cells and do not require a low intracellular Ca2+ concentration to initiate their replication cycle
    M A Cuadras
    Departamento de Genetica y Fisiologia Molecular, Instituto de Biotecnologia, Universidad Nacional Autonoma de Mexico, Cuernavaca, Morelos
    J Virol 71:9065-74. 1997
    ....
  13. ncbi request reprint RNA silencing of rotavirus gene expression
    Carlos F Arias
    Departamento de Genética del Desarrollo y Fisiología Molecular, Instituto de Biotecnologia, Universidad Nacional Autonoma de Mexico, Avenida Universidad 2001, Col Chamilpa, Cuernavaca, Morelos 62210, Mexico
    Virus Res 102:43-51. 2004
    ..Although the use of RNAi as an antiviral therapeutic tool remains to be demonstrated, there is no doubt that this technology will influence drastically the way postgenomic virus research is conducted...
  14. pmc Analysis of the kinetics of transcription and replication of the rotavirus genome by RNA interference
    Camilo Ayala-Breton
    Departamento de Genética del Desarrollo y Fisiología Molecular, Instituto de Biotecnologia, UNAM, Cuernavaca, Morelos 62210, Mexico
    J Virol 83:8819-31. 2009
    ....
  15. pmc Biochemical characterization of rotavirus receptors in MA104 cells
    C A Guerrero
    Departamento de Genetica y Fisiologia Molecular, Instituto de Biotecnologia, Centro de Instrumentos, Universidad Nacional Autonoma de Mexico, Cuernavaca, Morelos 62250, Mexico
    J Virol 74:9362-71. 2000
    ..Five individual protein bands of 30, 45, 57, 75, and 110 kDa, which exhibited virus-blocking activity, were finally isolated from the OG extract. These proteins are good candidates to function as rotavirus receptors...
  16. pmc Rotavirus gene silencing by small interfering RNAs
    Miguel Angel Déctor
    Departamento de Genética del Desarrollo y Fisiología Molecular, Instituto de Biotecnologia, Universidad Nacional Autonoma de Mexico, Av Universidad 2001, Cuernavaca, Morelos 62210, Mexico
    EMBO Rep 3:1175-80. 2002
    ..The VP4 gene silencing was specific, since the synthesis of VP4 from rotavirus strains that differ in the target sequence was not affected. These findings offer the possibility of carrying out reverse genetics in rotaviruses...
  17. ncbi request reprint Reduced expression of the rotavirus NSP5 gene has a pleiotropic effect on virus replication
    Tomàs López
    Departamento de Genética del Desarrollo y Fisiología Molecular, Instituto de Biotecnologia, Universidad Nacional Autonoma de Mexico, Avenida Universidad 2001, Col Chamilpa, Cuernavaca, Morelos 62210, Mexico
    J Gen Virol 86:1609-17. 2005
    ..The data presented in this work suggest that NSP5 is a key protein during the replication cycle of rotaviruses...
  18. pmc VP7 mediates the interaction of rotaviruses with integrin alphavbeta3 through a novel integrin-binding site
    Selene Zárate
    Departamento de Genética del Desarrollo y Fisiología Molecular, Instituto de Biotecnologia, Universidad Nacional Autonoma de Mexico, Avenida Universidad 2001, Col Chamilpa, Cuernavaca, Morelos 62210, Mexico
    J Virol 78:10839-47. 2004
    ..This region, which is highly conserved among the VP7 proteins of different rotavirus strains, mediates the binding of rotaviruses to integrin alphavbeta3 and probably represents a novel binding motif for this integrin...
  19. ncbi request reprint Early steps in rotavirus cell entry
    S Lopez
    Departamento de Genética del Desarrollo y Fisiología Molecular, Instituto de Biotecnologia, Universidad Nacional Autonoma de Mexico, 62210 Cuernavaca, Mexico
    Curr Top Microbiol Immunol 309:39-66. 2006
    ..This review focuses on recent data describing the interactions between the virus and its receptors, the role of lipid microdomains in rotavirus infection, and the possible mechanism of rotavirus cell entry...
  20. ncbi request reprint Role of sialic acids in rotavirus infection
    Pavel Isa
    Departamento de Genética del Desarrollo y Fisiología Molecular, Instituto de Biotecnologia, Universidad Nacional Autonoma de Mexico, Cuernavaca, Morelos 62210, Mexico
    Glycoconj J 23:27-37. 2006
    ....
  21. pmc Association of the astrovirus structural protein VP90 with membranes plays a role in virus morphogenesis
    Ernesto Méndez
    Departamento de Genética del Desarrollo y Fisiología Molecular, Instituto de Biotecnologia, Universidad Nacional Autonoma de Mexico, Apartado Postal 510 3, Colonia Miraval, Cuernavaca, Morelos 62250, Mexico
    J Virol 81:10649-58. 2007
    ....
  22. pmc Rotavirus infection induces the phosphorylation of eIF2alpha but prevents the formation of stress granules
    Hilda Montero
    Instituto de Biotecnologia, UNAM, Avenida Universidad 2001, Colonia Chamilpa, Cuernavaca, Morelos 62210, Mexico
    J Virol 82:1496-504. 2008
    ....
  23. doi request reprint Infectivity and genome persistence of rotavirus and astrovirus in groundwater and surface water
    Ana Cecilia Espinosa
    Instituto de Ecologia, Universidad Nacional Autonoma de Mexico UNAM, Tercer Circuito Escolar, Ciudad Universitaria, Coyoacan 04510, Mexico DF
    Water Res 42:2618-28. 2008
    ..78 and 1.3 logs, respectively. The longer persistence of viruses in this study could result from a combination of factors, including aggregation of the virus...
  24. pmc Endoplasmic reticulum chaperones are involved in the morphogenesis of rotavirus infectious particles
    Liliana Maruri-Avidal
    Departamento de Genética del Desarrollo y Fisiología Molecular, Instituto de Biotecnologia, Universidad Nacional Autonoma de Mexico, Cuernavaca, Morelos 62210, Mexico
    J Virol 82:5368-80. 2008
    ..The complexity of the steps of rotavirus assembly that occur in the ER provide a useful model for studying the organization and operation of the complex network of chaperones involved in maintaining the quality control of this organelle...
  25. doi request reprint Dissecting the role of integrin subunits alpha 2 and beta 3 in rotavirus cell entry by RNA silencing
    Pavel Isa
    Departamento de Genética del Desarrollo y Fisiología Molecular, Instituto de Biotecnologia, Universidad Nacional Autonoma de Mexico, Av Universidad 2001, Col Chamilpa, CP 62210 Cuernavaca, Morelos, Mexico
    Virus Res 145:251-9. 2009
    ..Altogether these data suggest that integrins alpha2 and alpha v beta 3 do not play a major role in the rotavirus entry process...
  26. pmc Protein products of the open reading frames encoding nonstructural proteins of human astrovirus serotype 8
    Ernesto Méndez
    Departamento de Genetica y Fisiologia Molecular, Instituto de Biotecnologia, Universidad Nacional Autonoma de Mexico, Colonia Miraval, Cuernavaca, Morelos 62250, Mexico
    J Virol 77:11378-84. 2003
    ..Based on the differential reactivities of the astrovirus proteins with the various antisera used, the individual polypeptides detected were mapped to the virus ORF1a and ORF1b regions...
  27. pmc Proteolytic processing of a serotype 8 human astrovirus ORF2 polyprotein
    Ernesto Méndez
    Departamento de Genetica y Fisiologia Molecular, Instituto de Biotecnologia, Universidad Nacional Autonoma de Mexico, Colonia Miraval, Cuernavaca, Morelos 62250, Mexico
    J Virol 76:7996-8002. 2002
    ..Based on these data, the processing pathway for the 90-kDa primary product of astrovirus Yuc8 ORF2 is presented...
  28. ncbi request reprint Preface. Virus gene silencing by RNA interference
    Susana Lopez
    Dept de Genetica del Desarrollo y Fisiologia Molecular, Instituto de Biotecnologia, Universidad Nacional Autonoma de Mexico, Avenida Universidad 2001, Col Chamilpa, Cuernavaca, Morelos 62210, Mexico
    Virus Res 102:1-2. 2004
  29. pmc Caspases mediate processing of the capsid precursor and cell release of human astroviruses
    Ernesto Méndez
    Instituto de Biotecnologia, Universidad Nacional Autonoma de Mexico, Apartado Postal 510 3, Colonia Miraval, Cuernavaca, Morelos 62250, Mexico
    J Virol 78:8601-8. 2004
    ..This is the first report that describes the induction and utilization of caspase activity by a virus to promote processing of the capsid precursor and dissemination of the viral particles...
  30. ncbi request reprint Rotavirus RRV associates with lipid membrane microdomains during cell entry
    Pavel Isa
    Departamento de Genética del Desarrollo y Fisiología Molecular, Instituto de Biotecnologia, Universidad Nacional Autonoma de Mexico, Cuernavaca, Morelos CP 62210, Mexico
    Virology 322:370-81. 2004
    ....
  31. doi request reprint Rotaviruses require basolateral molecules for efficient infection of polarized MDCKII cells
    Mauricio Realpe
    Departamento de Genética del Desarrollo y Fisiología Molecular, Instituto de Biotecnologia, Universidad Nacional Autonoma de Mexico, Av Universidad 2001, Col Chamilpa, Cuernavaca, Morelos CP 62210, Mexico
    Virus Res 147:231-41. 2010
    ....
  32. pmc Heat shock cognate protein 70 is involved in rotavirus cell entry
    Carlos A Guerrero
    , , , Cuernavaca, Morelos 62250, Mexico, USA
    J Virol 76:4096-102. 2002
    ..We propose that the functional rotavirus receptor is a complex of several cell surface molecules that include, among others, hsc70...
  33. ncbi request reprint Multistep entry of rotavirus into cells: a Versaillesque dance
    Susana Lopez
    Departamento de Genética del Desarrollo y Fisiología Molecular, Instituto de Biotecnologia, Universidad Nacional Autonoma de Mexico, Cuernavaca, Morelos 62210, Mexico
    Trends Microbiol 12:271-8. 2004
    ..This review focuses on recent data describing the virus-receptor interactions, the role of lipid microdomains in rotavirus infection and the mechanism of rotavirus cell entry...
  34. ncbi request reprint Heat shock enhances the susceptibility of BHK cells to rotavirus infection through the facilitation of entry and post-entry virus replication steps
    Tomàs López
    Departamento de Genética del Desarrollo y Fisiología Molecular, Instituto de Biotecnologia, Universidad Nacional Autonoma de Mexico UNAM, Av Universidad 2001, Colonia Chamilpa, Cuernavaca, Morelos 62210, Mexico
    Virus Res 121:74-83. 2006
    ..The pathway of virus entry into heat-shocked BHK cells seems to be similar to that used in MA104 cells, since treatments that affect MA104 cell infection also affected rotavirus infectivity in heat-treated BHK cells...
  35. pmc The peptide-binding and ATPase domains of recombinant hsc70 are required to interact with rotavirus and reduce its infectivity
    Jimena Pérez-Vargas
    Departamento de Genética del Desarrollo y Fisiología Molecular, Instituto de Biotecnologia, UNAM, Av Universidad 2001, Col Chamilpa, Cuernavaca, Morelos 62210, Mexico
    J Virol 80:3322-31. 2006
    ....
  36. ncbi request reprint Influence of calcium on the early steps of rotavirus infection
    Victoria Pando
    Departamento de Genetica y Fisiologia Molecular, Universidad Nacional Autonoma de Mexico, Cuernavaca, 62250, Mexico
    Virology 295:190-200. 2002
    ....
  37. pmc Interaction of rotaviruses with Hsc70 during cell entry is mediated by VP5
    Selene Zárate
    Departamento de Genética del Desarrollo y Fisiología Molecular, Instituto de Biotecnologia, Universidad Nacional Autonoma de Mexico, Cuernavaca, Morelos 62250, Mexico
    J Virol 77:7254-60. 2003
    ....
  38. doi request reprint Characterization of a persistent respiratory syncytial virus showing a low-fusogenic activity associated to an impaired F protein
    R E Sarmiento
    Departamento de Microbiologia y Parasitologia, Facultad de Medicina, Universidad Nacional Autonoma de Mexico, Mexico D F 04510, Mexico
    Virus Res 139:39-47. 2009
    ....
  39. pmc Prevalence and genetic diversity of human astroviruses in Mexican children with symptomatic and asymptomatic infections
    Martha Méndez-Toss
    Instituto de Biotecnologia, Universidad Nacional Autonoma de Mexico, Cuernavaca, Morelos, Mexico
    J Clin Microbiol 42:151-7. 2004
    ..Enteric adenoviruses were also studied, and they were found to be present in 2.3 (12 of 522) and 1.4% (6 of 428) of symptomatic and asymptomatic children, respectively...
  40. pmc Characterization of rotavirus cell entry
    Claudia Sánchez-San Martín
    Departamento de Genética del Desarrollo y Fisiología Molecular, Instituto de Biotecnologia, Universidad Nacional Autonoma de Mexico, Cuernavaca, Morelos 62210, Mexico
    J Virol 78:2310-8. 2004
    ....
  41. ncbi request reprint Rotavirus vaccine: early introduction in Latin America-risks and benefits
    Jimena Pérez-Vargas
    Departamento de Genética del Desarrollo y Fisiología Molecular, Instituto de Biotecnologia, Universidad Nacional Autonoma de Mexico, Cuernavaca, Morelos, Mexico
    Arch Med Res 37:1-10. 2006
    ....
  42. pmc Different rotavirus strains enter MA104 cells through different endocytic pathways: the role of clathrin-mediated endocytosis
    Michelle Gutierrez
    Departamento de Genética del Desarrollo y Fisiología Molecular, Instituto de Biotecnologia, UNAM, Avenida Universidad 2001, Col Chamilpa, Cuernavaca, Morelos 62210, Mexico
    J Virol 84:9161-9. 2010
    ..The inhibition of other endocytic mechanisms, such as macropinocytosis or caveola-mediated uptake, had no effect on the internalization of the rotavirus strains tested here...
  43. pmc Rotavirus diarrhea severity is related to the VP4 type in Mexican children
    Felipe Mota-Hernández
    Departamento de Medicina Comunitaria e Hidratación Oral, Hospital Infantil de Mexico Federico Gomez, Mexico City, Mexico
    J Clin Microbiol 41:3158-62. 2003
    ..The relationship between serotype and clinical outcomes seems to be complex and to vary among different geographic areas...
  44. ncbi request reprint The rotavirus surface protein VP8 modulates the gate and fence function of tight junctions in epithelial cells
    Porfirio Nava
    Department of Physiology, Biophysics and Neuroscience, Center for Research and Advanced Studies CINVESTAV, Mexico DF 07000, Mexico
    J Cell Sci 117:5509-19. 2004
    ..VP8 given orally to diabetic rats allows the enteral administration of insulin, thus indicating that it can be employed to modulate epithelial permeability...