Roopika Menon

Summary

Publications

  1. pmc Exome Enrichment and SOLiD Sequencing of Formalin Fixed Paraffin Embedded (FFPE) Prostate Cancer Tissue
    Roopika Menon
    Department of Prostate Cancer Research, Institute of Pathology, University Hospital of Bonn, Bonn 53127, Germany E Mails R M M D D B M B
    Int J Mol Sci 13:8933-42. 2012
  2. pmc The HOPE fixation technique--a promising alternative to common prostate cancer biobanking approaches
    Martin Braun
    Institute of Prostate Cancer Research, Institute of Pathology, University Hospital Bonn, Sigmund Freud Strasse 25, 53127 Bonn, Germany
    BMC Cancer 11:511. 2011
  3. ncbi request reprint MED15, encoding a subunit of the mediator complex, is overexpressed at high frequency in castration-resistant prostate cancer
    Zaki Shaikhibrahim
    Department of Prostate Cancer Research, University Hospital of Bonn, Bonn, Germany Institute of Pathology, University Hospital of Bonn, Bonn, Germany
    Int J Cancer 135:19-26. 2014
  4. ncbi request reprint Somatic copy number alterations by whole-exome sequencing implicates YWHAZ and PTK2 in castration-resistant prostate cancer
    Roopika Menon
    Department of Prostate Cancer Research, University Hospital of Bonn, Germany Institute of Pathology, University Hospital of Bonn, Germany
    J Pathol 231:505-16. 2013

Collaborators

Detail Information

Publications4

  1. pmc Exome Enrichment and SOLiD Sequencing of Formalin Fixed Paraffin Embedded (FFPE) Prostate Cancer Tissue
    Roopika Menon
    Department of Prostate Cancer Research, Institute of Pathology, University Hospital of Bonn, Bonn 53127, Germany E Mails R M M D D B M B
    Int J Mol Sci 13:8933-42. 2012
    ..fresh frozen samples using other NGS platforms. Our validation further proves that FFPE material is a reliable source of material for whole exome sequencing...
  2. pmc The HOPE fixation technique--a promising alternative to common prostate cancer biobanking approaches
    Martin Braun
    Institute of Prostate Cancer Research, Institute of Pathology, University Hospital Bonn, Sigmund Freud Strasse 25, 53127 Bonn, Germany
    BMC Cancer 11:511. 2011
    ..Aim of the study was to compare HOPE-fixed, FFPE and fresh-frozen bio-specimens for their accessibility for diagnostic and research purposes...
  3. ncbi request reprint MED15, encoding a subunit of the mediator complex, is overexpressed at high frequency in castration-resistant prostate cancer
    Zaki Shaikhibrahim
    Department of Prostate Cancer Research, University Hospital of Bonn, Bonn, Germany Institute of Pathology, University Hospital of Bonn, Bonn, Germany
    Int J Cancer 135:19-26. 2014
    ..Taken together, these findings implicate MED15 in CRPC, and as MED15 is evolutionary conserved, it is likely to emerge as a lethal phenotype in other therapeutic-resistant diseases, and not restricted to our disease model. ..
  4. ncbi request reprint Somatic copy number alterations by whole-exome sequencing implicates YWHAZ and PTK2 in castration-resistant prostate cancer
    Roopika Menon
    Department of Prostate Cancer Research, University Hospital of Bonn, Germany Institute of Pathology, University Hospital of Bonn, Germany
    J Pathol 231:505-16. 2013
    ..Furthermore, our validated whole-exome sequencing data show that FFPE tissue could be a promising alternative for SCNA screening using next-generation sequencing technologies...