E O Meltzer

Summary

Publications

  1. ncbi Formulation considerations of intranasal corticosteroids for the treatment of allergic rhinitis
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, California 92123 2661, USA
    Ann Allergy Asthma Immunol 98:12-21. 2007
  2. ncbi Onset of therapeutic effect of fluticasone propionate aqueous nasal spray
    E O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, CA 92123, USA
    Ann Allergy Asthma Immunol 86:286-91. 2001
  3. pmc Treatment of congestion in upper respiratory diseases
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, CA and Department of Pediatrics, University of California, San Diego, USA
    Int J Gen Med 3:69-91. 2010
  4. pmc Randomized, Cross-Over Evaluation of Mobile Phone vs Paper Diary in Subjects with Mild to Moderate Persistent Asthma
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, CA, USA
    Open Respir Med J 2:72-9. 2008
  5. doi Pharmacotherapeutic strategies for allergic rhinitis: matching treatment to symptoms, disease progression, and associated conditions
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, CA 92123, USA
    Allergy Asthma Proc 34:301-11. 2013
  6. doi Mometasone furoate nasal spray plus oxymetazoline nasal spray: short-term efficacy and safety in seasonal allergic rhinitis
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, California 92123, USA
    Am J Rhinol Allergy 27:102-8. 2013
  7. pmc Relieving nasal congestion in children with seasonal and perennial allergic rhinitis: efficacy and safety studies of mometasone furoate nasal spray
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, California, USA
    World Allergy Organ J 6:5. 2013
  8. doi Burden of allergic rhinitis: allergies in America, Latin America, and Asia-Pacific adult surveys
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, 5776 Ruffin Road, San Diego, CA 92123, USA
    Allergy Asthma Proc 33:S113-41. 2012
  9. doi MP29-02 (a novel intranasal formulation of azelastine hydrochloride and fluticasone propionate) in the treatment of seasonal allergic rhinitis: a randomized, double-blind, placebo-controlled trial of efficacy and safety
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, California 92123, USA
    Allergy Asthma Proc 33:324-32. 2012
  10. ncbi Safety and efficacy of once-daily treatment with beclomethasone dipropionate nasal aerosol in subjects with perennial allergic rhinitis
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, California, USA
    Allergy Asthma Proc 33:249-57. 2012

Detail Information

Publications87

  1. ncbi Formulation considerations of intranasal corticosteroids for the treatment of allergic rhinitis
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, California 92123 2661, USA
    Ann Allergy Asthma Immunol 98:12-21. 2007
    ..To examine how various aspects of an intranasal corticosteroid (INS) formulation may influence the efficacy, tolerability, and patient preference and adherence to INS therapy...
  2. ncbi Onset of therapeutic effect of fluticasone propionate aqueous nasal spray
    E O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, CA 92123, USA
    Ann Allergy Asthma Immunol 86:286-91. 2001
    ..The onset of therapeutic effect of FP in these clinical trials appears to occur within 12 hours after administration of the initial dose...
  3. pmc Treatment of congestion in upper respiratory diseases
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, CA and Department of Pediatrics, University of California, San Diego, USA
    Int J Gen Med 3:69-91. 2010
    ....
  4. pmc Randomized, Cross-Over Evaluation of Mobile Phone vs Paper Diary in Subjects with Mild to Moderate Persistent Asthma
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, CA, USA
    Open Respir Med J 2:72-9. 2008
    ..The greater prevalence of missing data when using this diary most likely results from the inability to backfill missing entries. TRIAL REGISTRATION: Clintrials.gov NCT00367263 (http://clinicaltrials.gov/ct2/show/NCT00367263)...
  5. doi Pharmacotherapeutic strategies for allergic rhinitis: matching treatment to symptoms, disease progression, and associated conditions
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, CA 92123, USA
    Allergy Asthma Proc 34:301-11. 2013
    ..A step-up/step-down approach to AR pharmacotherapy based on patient response may hold the potential for optimal control of AR symptoms while minimizing side effects and cost of treatment. ..
  6. doi Mometasone furoate nasal spray plus oxymetazoline nasal spray: short-term efficacy and safety in seasonal allergic rhinitis
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, California 92123, USA
    Am J Rhinol Allergy 27:102-8. 2013
    ..This study was designed to assess the efficacy of the combination of MFNS and OXY for the relief of seasonal allergic rhinitis (SAR) symptoms...
  7. pmc Relieving nasal congestion in children with seasonal and perennial allergic rhinitis: efficacy and safety studies of mometasone furoate nasal spray
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, California, USA
    World Allergy Organ J 6:5. 2013
    ..This analysis was conducted to investigate the effect of mometasone furoate nasal spray (MFNS) on congestion in children with AR...
  8. doi Burden of allergic rhinitis: allergies in America, Latin America, and Asia-Pacific adult surveys
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, 5776 Ruffin Road, San Diego, CA 92123, USA
    Allergy Asthma Proc 33:S113-41. 2012
    ..These findings support the assertion that AR burden has been substantially underestimated and identify several important challenges to successful management of AR...
  9. doi MP29-02 (a novel intranasal formulation of azelastine hydrochloride and fluticasone propionate) in the treatment of seasonal allergic rhinitis: a randomized, double-blind, placebo-controlled trial of efficacy and safety
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, California 92123, USA
    Allergy Asthma Proc 33:324-32. 2012
    ..In this study, MP29-02 provided more complete symptom relief than two widely used first-line AR treatments and was well tolerated...
  10. ncbi Safety and efficacy of once-daily treatment with beclomethasone dipropionate nasal aerosol in subjects with perennial allergic rhinitis
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, California, USA
    Allergy Asthma Proc 33:249-57. 2012
    ..Additionally, treatment with BDP nasal aerosol was well tolerated with a safety profile comparable to that of placebo. This study was part of the clinical trial NCT01134705 registered in www.ClinicalTrials.gov...
  11. doi Mometasone furoate nasal spray increases the number of minimal-symptom days in patients with acute rhinosinusitis
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, California 92123, USA
    Ann Allergy Asthma Immunol 108:275-9. 2012
    ..Acute rhinosinusitis (ARS) is triggered by viral or, uncommonly, bacterial infection, causing inflammatory symptoms for ≤12 weeks...
  12. doi Asthma burden in the United States: results of the 2009 Asthma Insight and Management survey
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, California 92123, USA
    Allergy Asthma Proc 33:36-46. 2012
    ..Asthma care in the United States remains suboptimal, indicating the need for continued improvements in patient management...
  13. doi Mometasone furoate/formoterol reduces asthma deteriorations and improves lung function
    E O Meltzer
    Allergy and Asthma Medical Group and Research Center, 9610 Granite Ridge Drive, Suite B, San Diego, CA 92123, USA
    Eur Respir J 39:279-89. 2012
    ..MF/F 100/10 μg b.i.d. treatment showed greater clinical efficacy than its individual components or placebo; both components contributed to the efficacy of MF/F...
  14. ncbi Allergic rhinitis: the impact of discordant perspectives of patient and physician on treatment decisions
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, California 92123, USA
    Clin Ther 29:1428-40. 2007
    ..However, despite its high prevalence and significant impact on health-related quality of life (HRQOL) and productivity, AR may be undertreated. This might arise, in part, from the low priority given to the disease by physicians...
  15. ncbi Efficacy of fexofenadine versus desloratadine in suppressing histamine-induced wheal and flare
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, University of California at San Diego, San Diego, California, USA
    Allergy Asthma Proc 28:67-73. 2007
    ..Fexofenadine HCl, 180 mg, was superior to desloratadine, 5 mg, in histamine-induced wheal-and-flare suppression, suggesting increased in vivo H1-receptor antagonist potency of fexofenadine versus desloratadine...
  16. ncbi Efficacy and safety of ciclesonide, 200 microg once daily, for the treatment of perennial allergic rhinitis
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, California 92123 2661, USA
    Ann Allergy Asthma Immunol 98:175-81. 2007
    ..Ciclesonide is an intranasal corticosteroid approved for the treatment of allergic rhinitis (AR)...
  17. ncbi The efficacy and safety of mometasone furoate delivered via a dry powder inhaler for the treatment of asthma
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, University of California San Diego, 9610 Granite Ridge Drive, San Diego, CA 92123, USA
    J Asthma 43:765-72. 2006
    ..In conclusion, mometasone furoate provides primary care and specialty physicians with a safe, effective, and convenient option to meet the challenges of asthma management...
  18. ncbi The systemic safety of inhaled corticosteroid therapy: a focus on ciclesonide
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, California 92123, USA
    Ann Allergy Asthma Immunol 97:149-57. 2006
    ..To review the potential systemic activity of ciclesonide and its active metabolite, desisobutyryl-ciclesonide, by evaluation of the effects on hypothalamic-pituitary-adrenal (HPA) axis function...
  19. ncbi Allergic rhinitis: managing the pediatric spectrum
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, California 92123, USA
    Allergy Asthma Proc 27:2-8. 2006
    ..Allergen immunotherapy can be a valuable adjunctive modality. Issues of compliance and convenience also are important considerations...
  20. ncbi Optimal management of community-acquired acute bacterial rhinosinusitis: the allergist's perspective
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, CA 92123, USA
    Ann Allergy Asthma Immunol 96:390-7. 2006
    ....
  21. ncbi Effect of desloratadine therapy on symptom scores and measures of nasal patency in seasonal allergic rhinitis: results of a single-center, placebo-controlled trial
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, California 92123, USA
    Ann Allergy Asthma Immunol 96:363-8. 2006
    ..Desloratadine reduces symptoms and maintains nasal airflow in patients with seasonal allergic rhinitis (SAR) during experimental allergen exposure...
  22. doi Preferences of adult patients with allergic rhinitis for the sensory attributes of fluticasone furoate versus fluticasone propionate nasal sprays: a randomized, multicenter, double-blind, single-dose, crossover study
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, California, USA
    Clin Ther 30:271-9. 2008
    ..Product attributes influence patient preference for intranasal corticosteroid therapy in allergic rhinitis (AR)...
  23. ncbi Intranasal corticosteroids in the treatment of acute rhinosinusitis
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, CA 92123, USA
    Curr Allergy Asthma Rep 8:133-8. 2008
    ....
  24. doi Efficacy and safety of once-daily fluticasone furoate nasal spray in children with seasonal allergic rhinitis treated for 2 wk
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, 9610 Granite Ridge Drive, Suite B, San Diego, CA 92123, USA
    Pediatr Allergy Immunol 20:279-86. 2009
    ..Both doses of FF were well tolerated. These study results suggest that FF nasal spray administered once daily for 2 wk is well tolerated and effective for the treatment of SAR symptoms in children aged 2-11 yr...
  25. pmc Rhinosinusitis diagnosis and management for the clinician: a synopsis of recent consensus guidelines
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, 9610 Granite Ridge Dr, Ste B, San Diego, CA 92123, USA
    Mayo Clin Proc 86:427-43. 2011
    ..Important and relevant data from MEDLINE-indexed articles published since the most recent guidelines were issued are also considered, and needs for future research are discussed...
  26. doi Mometasone furoate nasal spray for moderate-to-severe nasal congestion in subjects with seasonal allergic rhinitis
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, California 92123, USA
    Allergy Asthma Proc 32:159-67. 2011
    ..Adverse events were infrequent and localized; the most common (epistaxis and pharyngolaryngeal pain) occurred in 1.0% of MFNS patients. MFNS q.d. provides sustained relief for nasal congestion and other SAR symptoms...
  27. doi Use of the Asthma Control Questionnaire to predict future risk of asthma exacerbation
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, Calif 92123, USA
    J Allergy Clin Immunol 127:167-72. 2011
    ..Direct correlation of assessments of a validated composite measure such as the Asthma Control Questionnaire (ACQ) and risk of exacerbation has not been previously demonstrated in a randomized controlled trial...
  28. ncbi Intranasal mometasone furoate therapy for allergic rhinitis symptoms and rhinitis-disturbed sleep
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, California 92123, USA
    Ann Allergy Asthma Immunol 105:65-74. 2010
    ..Allergic rhinitis (AR) and related nasal congestion cause rhinitis-disturbed sleep (RDS). Intranasal corticosteroids reduce nasal congestion and improve sleep quality in AR but have not been extensively studied in RDS...
  29. doi Comparison of patient preference for sensory attributes of fluticasone furoate or fluticasone propionate in adults with seasonal allergic rhinitis: a randomized, placebo-controlled, double-blind study
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, California 92123, USA
    Ann Allergy Asthma Immunol 104:331-8. 2010
    ..Intranasal corticosteroids are first-line treatment for moderate-to-severe seasonal allergic rhinitis (AR)...
  30. doi Burden of allergic rhinitis: results from the Pediatric Allergies in America survey
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, CA 92123, USA
    J Allergy Clin Immunol 124:S43-70. 2009
    ..Findings from this national survey have identified important challenges to the management of AR, suggesting that its burden on children in the United States has been significantly underestimated...
  31. doi Efficacy and safety evaluation of ciclesonide in mild-to-moderate persistent asthma previously treated with inhaled corticosteroids
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, California, USA
    Allergy Asthma Proc 30:293-303. 2009
    ..i.d. maintained asthma control in subjects with stable mild-to-moderate asthma previously treated with ICS or ICS/LABA, was well tolerated, and, in general, was better than CIC160 q.d. in maintaining disease control...
  32. doi Comparative study of sensory attributes of two antihistamine nasal sprays: olopatadine 0.6% and azelastine 0.1%
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, CA 92123, USA
    Allergy Asthma Proc 29:659-68. 2008
    ..This outcome could lead to greater patient compliance and improved treatment effect...
  33. doi Safety and tolerability of fluticasone furoate nasal spray once daily in paediatric patients aged 6-11 years with allergic rhinitis: subanalysis of three randomized, double-blind, placebo-controlled, multicentre studies
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, California 92123, USA
    Clin Drug Investig 29:79-86. 2009
    ....
  34. ncbi Safety and efficacy of olopatadine hydrochloride nasal spray for the treatment of seasonal allergic rhinitis
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, California 92123, USA
    Ann Allergy Asthma Immunol 95:600-6. 2005
    ..A nasal spray containing the antiallergy agent olopatadine hydrochloride is being developed for the treatment of seasonal allergic rhinitis (SAR)...
  35. ncbi Treating acute rhinosinusitis: comparing efficacy and safety of mometasone furoate nasal spray, amoxicillin, and placebo
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, CA 92123, USA
    J Allergy Clin Immunol 116:1289-95. 2005
    ..However, the efficacy of intranasal corticosteroid monotherapy for acute, uncomplicated rhinosinusitis is not established...
  36. ncbi Allergic rhinitis, asthma, and rhinosinusitis: diseases of the integrated airway
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, University of California at San Diego, San Diego, CA 92123, USA
    J Manag Care Pharm 10:310-7. 2004
    ..Controlling upper airway inflammation and symptoms among asthma patients may help improve health and economic outcomes...
  37. ncbi Rhinosinusitis: Establishing definitions for clinical research and patient care
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, Department of Pediatrics, University of California, San Diego 92123, USA
    Otolaryngol Head Neck Surg 131:S1-62. 2004
  38. ncbi Rhinosinusitis: establishing definitions for clinical research and patient care
    Eli O Meltzer
    Department of Pediatrics, Allergy and Asthma Medical Group and Research Center, 9610 Granite Ridge Drive, Suite B, San Diego, CA 92123, USA
    J Allergy Clin Immunol 114:155-212. 2004
  39. doi The role of nasal corticosteroids in the treatment of rhinitis
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, 5776 Ruffin Road, San Diego, CA 92123, USA
    Immunol Allergy Clin North Am 31:545-60. 2011
    ..Clinically, they have been shown to be the most effective class of nasal medications for treating allergic rhinitis and nonallergic rhinopathy, with no clear evidence that any specific INS is superior to others...
  40. ncbi Efficacy and safety of low-dose fluticasone propionate compared with montelukast for maintenance treatment of persistent asthma
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, CA 92123, USA
    Mayo Clin Proc 77:437-45. 2002
    ..To compare the long-term effects of an inhaled corticosteroid with those of a leukotriene modifier on measures of clinical efficacy, subject preference, and safety in patients with persistent asthma...
  41. ncbi Development of questionnaires to measure patient preferences for intranasal corticosteroids in patients with allergic rhinitis
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, CA 92123, USA
    Otolaryngol Head Neck Surg 132:197-207. 2005
    ..To develop a questionnaire to evaluate preferences for attributes of intranasal corticosteroids (INSs) in clinical trials with allergic rhinitis (AR) patients...
  42. ncbi Clinical evidence for antileukotriene therapy in the management of allergic rhinitis
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, California 92123, USA
    Ann Allergy Asthma Immunol 88:23-9. 2002
    ..After reading this article, readers will have a greater understanding of these clinical findings and their implications for the management of allergic rhinitis...
  43. ncbi An intranasal Syk-kinase inhibitor (R112) improves the symptoms of seasonal allergic rhinitis in a park environment
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, 9610 Granite Ridge Drive, Suite B, San Diego, CA 92123 2661, USA
    J Allergy Clin Immunol 115:791-6. 2005
    ..R112 inhibits Syk kinase, a transducer of signaling through the Fcepsilon receptor of mast cells, blocking mast cell responses to allergic stimuli...
  44. ncbi Safety and efficacy of oral fexofenadine in children with seasonal allergic rhinitis--a pooled analysis of three studies
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, CA, USA
    Pediatr Allergy Immunol 15:253-60. 2004
    ..05). Fexofenadine, at doses of up to 60 mg b.i.d., is safe and non-sedating, and fexofenadine HCl 30 mg b.i.d. effectively reduces all seasonal allergic rhinitis symptoms in children aged 6-11 years...
  45. ncbi Evaluation of the optimal oral antihistamine for patients with allergic rhinitis
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, 9610 Granite Ridge Dr, Suite B, San Diego, CA 92123, USA
    Mayo Clin Proc 80:1170-6. 2005
    ..Therefore, agents with broad therapeutic windows, based on both efficacy and safety, are expected to be more favorable; this therapeutic window should be understood by the primary care physician when prescribing a medication...
  46. ncbi Quality of life in adults and children with allergic rhinitis
    E O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, CA 92123, USA
    J Allergy Clin Immunol 108:S45-53. 2001
    ..Agents that have troublesome adverse effects such as sedation can have a negative impact, whereas nonsedating antihistamines and intranasal cortico-steroids can significantly improve HRQL in patients of all ages with rhinitis...
  47. ncbi A preference evaluation study comparing the sensory attributes of mometasone furoate and fluticasone propionate nasal sprays by patients with allergic rhinitis
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, CA 92123, USA
    Treat Respir Med 4:289-96. 2005
    ....
  48. doi Physician perceptions of the treatment and management of allergic and nonallergic rhinitis
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, California, USA
    Allergy Asthma Proc 30:75-83. 2009
    ..This physician survey provides insight into perceptions of the impact of allergic rhinitis and nonallergic rhinitis on patients' quality of life and symptom severity...
  49. ncbi Efficacy and safety of clemastine-pseudoephedrine-acetaminophen versus pseudoephedrine-acetaminophen in the treatment of seasonal allergic rhinitis in a 1-day, placebo-controlled park study
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, California, USA
    Ann Allergy Asthma Immunol 90:79-86. 2003
    ..Patients with allergic rhinitis have a wide range of symptoms that are often treated with oral combination products that contain antihistamines, decongestants, and analgesics...
  50. ncbi Intranasal steroids: managing allergic rhinitis and tailoring treatment to patient preference
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, 9610 Granite Ridge Drive, Suite B, San Diego, CA 92123, USA
    Allergy Asthma Proc 26:445-51. 2005
    ..The development of two new questionnaires, the Clinical Practice Patient Preference Questionnaire and the Clinical Trial Patient Preference Questionnaire, may prove useful in selecting the optimal treatment regimen for patients...
  51. ncbi Montelukast effectively treats the nighttime impact of seasonal allergic rhinitis
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, CA 92109, USA
    Am J Rhinol 19:591-8. 2005
    ..Nighttime problems constitute a significant burden on the quality of life of patients with seasonal allergic rhinitis (SAR). The aim of this study was to evaluate the effectiveness of montelukast on nighttime AR symptoms...
  52. ncbi Effective dose range of mometasone furoate nasal spray in the treatment of acute rhinosinusitis
    Anjuli S Nayak
    Asthma and Allergy Research Associates, PC, Normal, Illinois 61761, USA
    Ann Allergy Asthma Immunol 89:271-8. 2002
    ..Mometasone furoate nasal spray (MFNS) 400 microg, twice daily, as adjunctive treatment with oral antibiotic significantly improved symptoms of recurrent rhinosinusitis...
  53. doi Safety and efficacy of olopatadine hydrochloride nasal spray 0.6% in pediatric subjects with allergic rhinitis
    William E Berger
    Department of Pediatrics, Division of Allergy and Immunology, University of California, Irvine, California, USA
    Allergy Asthma Proc 30:612-23. 2009
    ..In subjects 6 to <12 years of age, OLO was superior to vehicle in the treatment of SAR. In subjects 2 to <12 years of age, OLO had an overall low rate of AEs and low systemic exposure...
  54. ncbi Asthma management and environmental tobacco smoke exposure reduction in Latino children: a controlled trial
    Melbourne F Hovell
    Center for Behavioral Epidemiology and Community Health, Graduate School of Public Health, San Diego State University, San Diego, California 92123, USA
    Pediatrics 110:946-56. 2002
    ..This study tested the efficacy of coaching to reduce environmental tobacco smoke (ETS) exposure among asthmatic Latino children...
  55. ncbi Rhinosinusitis: Developing guidance for clinical trials
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center Department of Pediatrics, University of California, San Diego, San Diego, California
    Otolaryngol Head Neck Surg 135:S31-80. 2006
    ....
  56. ncbi Triamcinolone acetonide and fluticasone propionate aqueous nasal sprays significantly improve nasal airflow in patients with seasonal allergic rhinitis
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, California 92123, USA
    Allergy Asthma Proc 25:53-8. 2004
    ..Weekly mean nPIFR scores indicated progressive improvement in nasal airflow with both treatments. Both TAA AQ and FP AQ were effective for improving nasal airflow as indicated by increases in nPIFR in patients with SAR...
  57. ncbi Rhinosinusitis: developing guidance for clinical trials
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center and Department of Pediatrics, University of California, San Diego, USA
    J Allergy Clin Immunol 118:S17-61. 2006
    ....
  58. ncbi Intranasal fluocortin butyl in patients with perennial rhinitis: a 12-month efficacy and safety study including nasal biopsy
    H A Orgel
    Allergy and Asthma Medical Group and Research Center, San Diego, Calif
    J Allergy Clin Immunol 88:257-64. 1991
    ..There were few adverse effects. Mean plasma cortisol levels were normal before and after corticotropin stimulation at baseline and after 12 months of FCB therapy.(ABSTRACT TRUNCATED AT 250 WORDS)..
  59. ncbi The role of the immune system in the pathogenesis of asthma and an overview of the diagnosis, classification, and current approach to treating the disease
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, 9610 Granite Ridge Dr B, San Diego, CA 92123, USA
    J Manag Care Pharm 9:8-13. 2003
    ....
  60. ncbi Efficacy and patient satisfaction with cromolyn sodium nasal solution in the treatment of seasonal allergic rhinitis: a placebo-controlled study
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, California 92123, USA
    Clin Ther 24:942-52. 2002
    ..The mast-cell stabilizer cromolyn sodium is available for over-the-counter (OTC) use in the prevention and treatment of allergic rhinitis...
  61. ncbi Increasing asthma knowledge and changing home environments for Latino families with asthmatic children
    J A Jones
    Center for Behavioral Epidemiology and Community Health, Graduate School of Public Health, San Diego State University, San Diego, CA, USA
    Patient Educ Couns 42:67-79. 2001
    ..4 to 1.8, P < 0.001; mean number of controllers increased from 0.7 to 0.9, P < 0.001). The results support the value of asthma education and its importance in the national agenda to reduce health disparities among minorities...
  62. doi Psychometric validation of the rhinitis control assessment test: a brief patient-completed instrument for evaluating rhinitis symptom control
    Michael Schatz
    Kaiser Permanente, San Diego, California, USA
    Ann Allergy Asthma Immunol 104:118-24. 2010
    ..Allergic rhinitis is common, but a validated tool for comprehensive assessment of disease control is not available...
  63. ncbi H1-antihistamines and the central nervous system
    Michael J Welch
    Allergy and Asthma Medical Group and Research Center, University of California, San Diego, San Diego, California, USA
    Clin Allergy Immunol 17:337-88. 2002
    ....
  64. ncbi Introduction: Stuffy is also related to Sleepy and Grumpy--the link between rhinitis and sleep-disordered breathing
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, Department of Pediatrics, University of California San Diego, San Diego, CA, USA
    J Allergy Clin Immunol 114:S133-4. 2004
  65. ncbi Addition of ibuprofen to pseudoephedrine and chlorpheniramine in the treatment of seasonal allergic rhinitis
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, California, USA
    Ann Allergy Asthma Immunol 93:452-9. 2004
    ..Standard over-the-counter therapy with antihistamines and nasal decongestants often does not completely relieve all symptoms associated with allergic rhinitis...
  66. ncbi Latino children with asthma: rates and risks for medical care utilization
    Jill Berg
    UCLA School of Nursing, Los Angeles, California, USA
    J Asthma 41:147-57. 2004
    ..Quality and monitored health care with optimization of asthma management could reduce costly acute care services...
  67. ncbi Pharmacologic rationale for treating allergic and nonallergic rhinitis
    Alexander N Greiner
    Allergy and Asthma Medical Group and Research Center and the University of California San Diego School of Medicine, San Diego, CA 92123, USA
    J Allergy Clin Immunol 118:985-98. 2006
    ..Furthermore, appropriate stepped-up, stepped-down pharmacotherapeutic algorithms are described for the various forms of rhinitis...
  68. doi Sleep, quality of life, and productivity impact of nasal symptoms in the United States: findings from the Burden of Rhinitis in America survey
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, California, USA
    Allergy Asthma Proc 30:244-54. 2009
    ..05). Individuals who suffer from AR symptoms experience a substantial burden on their ability to sleep, quality of life, cognitive function, and school/workplace productivity...
  69. ncbi The relationships of rhinitis and asthma
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, 9610 Granite Ridge Drive, Suite B, San Diego, CA 92123, USA
    Allergy Asthma Proc 26:336-40. 2005
    ..To clarify the relationships between upper and lower airway disorders and to establish the potential benefits of an integrated airways management approach, additional studies are warranted...
  70. ncbi Impact of azelastine nasal spray on symptoms and quality of life compared with cetirizine oral tablets in patients with seasonal allergic rhinitis
    William Berger
    Southern California Research, Mission Viejo 92691, USA
    Ann Allergy Asthma Immunol 97:375-81. 2006
    ....
  71. ncbi Histamine skin test reactivity following single and multiple doses of azelastine nasal spray in patients with seasonal allergic rhinitis
    David S Pearlman
    Colorado Allergy and Asthma Centers, PC, Denver, Colorado 80230, USA
    Ann Allergy Asthma Immunol 91:258-62. 2003
    ..To determine whether azelastine nasal spray suppresses the dermal response to epicutaneous histamine in allergic patients and the duration of suppression after azelastine use is discontinued...
  72. ncbi Efficacy of desloratadine, 5 mg, compared with fexofenadine, 180 mg, in patients with symptomatic seasonal allergic rhinitis
    William E Berger
    Allergy and Asthma Associates of Southern California, Mission Viejo, California 92691, USA
    Allergy Asthma Proc 27:214-23. 2006
    ..All treatments were well tolerated. Desloratadine, 5 mg, and fexofenadine, 180 mg, provide comparable efficacy and tolerability in the treatment of SAR. Both treatments are significantly more effective than placebo...
  73. ncbi Use of intranasal cromolyn sodium for allergic rhinitis
    Paul H Ratner
    Sylvana Research Associates and Department of Pediatrics, University of Texas Health Science Center, San Antonio, USA
    Mayo Clin Proc 77:350-4. 2002
    ..Intranasal cromolyn has an excellent safety record, is available as an over-the-counter medication, and has been proved to be efficacious in patients with allergic rhinitis...
  74. ncbi Efficacy of montelukast during the allergy season in patients with chronic asthma and seasonal aeroallergen sensitivity
    William W Busse
    Department of Medicine, University of Wisconsin Medical School, Madison, Wisconsin 53792, USA
    Ann Allergy Asthma Immunol 96:60-8. 2006
    ..Montelukast has proven efficacy in the treatment of chronic asthma and seasonal allergic rhinitis, but it has not been evaluated in the subpopulation of asthmatic patients with seasonal asthma symptoms...
  75. doi Comprehensive report of the efficacy, safety, quality of life, and work impact of Olopatadine 0.6% and Olopatadine 0.4% treatment in patients with seasonal allergic rhinitis
    Carol J Fairchild
    Alcon Laboratories, Inc, 6201 South Freeway, Fort Worth, Texas 76134, USA
    Allergy Asthma Proc 28:716-23. 2007
    ..This analysis indicates that Olo is a safe and effective intranasal treatment and is associated with significant improvement in QoL and ability to perform work and conduct usual activities of SAR patients...
  76. ncbi No growth suppression in children treated with the maximum recommended dose of fluticasone propionate aqueous nasal spray for one year
    David B Allen
    University of Wisconsin Children s Hospital, 600 Highland Ave, Madison, Wisconsin 53792, USA
    Allergy Asthma Proc 23:407-13. 2002
    ....
  77. ncbi Intranasal fluticasone propionate is effective for perennial nonallergic rhinitis with or without eosinophilia
    D Robert Webb
    Allergy and Asthma Research Associates, Kirkland, Washington 98034, USA
    Ann Allergy Asthma Immunol 88:385-90. 2002
    ..Objective: To evaluate the efficacy of intranasal fluticasone propionate (FP) in the treatment of patients with perennial nonallergic rhinitis, with and without nasal eosinophilia...
  78. ncbi Requirements for medications commonly used in the treatment of allergic rhinitis. European Academy of Allergy and Clinical Immunology (EAACI), Allergic Rhinitis and its Impact on Asthma (ARIA)
    Jean Bousquet
    Allergy 58:192-7. 2003
  79. ncbi Fexofenadine is efficacious and safe in children (aged 6-11 years) with seasonal allergic rhinitis
    Ulrich Wahn
    Department of Pediatric Pneumology and Immunology, University Children s Hospital, Berlin, Germany
    J Allergy Clin Immunol 111:763-9. 2003
    ..This is the first prospective, randomized, double-blind, placebo-controlled study showing statistical improvement of an H(1)-antihistamine in children with seasonal allergic rhinitis in all symptoms throughout the entire treatment period...
  80. doi Efficacy and safety of fluticasone propionate/salmeterol 250/50 mcg Diskus administered once daily
    Edward M Kerwin
    Clinical Research Institute of Southern Oregon, Medford, OR 97504, USA
    Respir Med 102:495-504. 2008
    ..The once daily administration of an ICS/LABA may be a treatment option for some patients...
  81. doi Antibiotics and nasal steroids for acute sinusitis
    Eli O Meltzer
    JAMA 299:1422-3; author reply 1423. 2008
  82. ncbi Emerging therapeutic strategies for asthma management
    Sean D Sullivan
    Pharmaceutical Outcomes Research and Policy Program, Department of Pharmacy, University of Washington, 1959 NE Pacific Ave, Box 357630, Seattle, WA 98195, USA
    J Manag Care Pharm 9:14-21. 2003
    ..The describe the mechanisms of action of and clinical experience to date with novel asthma drug therapies...
  83. ncbi Effect of mometasone furoate nasal spray on quality of life of patients with acute rhinosinusitis
    Claus Bachert
    Ear, Nose and Throat Department, University Hospital, Ghent, Belgium
    Rhinology 45:190-6. 2007
    ..Treatment with MFNS 200 g b.i.d. is associated with a significant improvement in HRQoL compared with placebo in patients with acute, uncomplicated rhinosinusitis...
  84. ncbi Exploring new frontiers in asthma management for optimal therapeutic and economic outcomes
    Sean D Sullivan
    Pharmaceutical Outcomes Research and Policy Program, Department of Pharmacy, University of Washington, 1959 NE Pacific Ave, Box 357630, Seattle, WA 98195, USA
    J Manag Care Pharm 9:2. 2003
  85. ncbi Development and validation of the Congestion Quantifier seven-item test (CQ7): a screening tool for nasal congestion
    Donald E Stull
    United BioSource Corporation, Bethesda, MD 20814, USA
    Value Health 10:457-65. 2007
    ..Nevertheless, there is no short screening tool designed specifically to identify congestion that can help patients make decisions about seeking treatment...
  86. ncbi A questionnaire to measure quality of life in adults with nocturnal allergic rhinoconjunctivitis
    Elizabeth F Juniper
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    J Allergy Clin Immunol 111:484-90. 2003
    ..Many patients with rhinoconjunctivitis experience symptoms at night and these interfere with getting a good night's sleep...