Onset of therapeutic effect of fluticasone propionate aqueous nasal sprayE O Meltzer
Allergy and Asthma Medical Group and Research Center, San Diego, CA 92123, USA
Ann Allergy Asthma Immunol 86:286-91. 2001
..The onset of therapeutic effect of FP in these clinical trials appears to occur within 12 hours after administration of the initial dose...
Burden of allergic rhinitis: allergies in America, Latin America, and Asia-Pacific adult surveysEli O Meltzer
Allergy and Asthma Medical Group and Research Center, 5776 Ruffin Road, San Diego, CA 92123, USA
Allergy Asthma Proc 33:S113-41. 2012
..These findings support the assertion that AR burden has been substantially underestimated and identify several important challenges to successful management of AR...
- MP29-02 (a novel intranasal formulation of azelastine hydrochloride and fluticasone propionate) in the treatment of seasonal allergic rhinitis: a randomized, double-blind, placebo-controlled trial of efficacy and safety
Eli O Meltzer
Allergy and Asthma Medical Group and Research Center, San Diego, California 92123, USA
Allergy Asthma Proc 33:324-32. 2012
..In this study, MP29-02 provided more complete symptom relief than two widely used first-line AR treatments and was well tolerated...
- Safety and efficacy of once-daily treatment with beclomethasone dipropionate nasal aerosol in subjects with perennial allergic rhinitis
Eli O Meltzer
Allergy and Asthma Medical Group and Research Center, San Diego, California, USA
Allergy Asthma Proc 33:249-57. 2012
..Additionally, treatment with BDP nasal aerosol was well tolerated with a safety profile comparable to that of placebo. This study was part of the clinical trial NCT01134705 registered in www.ClinicalTrials.gov...
- Mometasone furoate nasal spray increases the number of minimal-symptom days in patients with acute rhinosinusitis
Eli O Meltzer
Allergy and Asthma Medical Group and Research Center, San Diego, California 92123, USA
Ann Allergy Asthma Immunol 108:275-9. 2012
..Acute rhinosinusitis (ARS) is triggered by viral or, uncommonly, bacterial infection, causing inflammatory symptoms for ≤12 weeks...
- Asthma burden in the United States: results of the 2009 Asthma Insight and Management survey
Eli O Meltzer
Allergy and Asthma Medical Group and Research Center, San Diego, California 92123, USA
Allergy Asthma Proc 33:36-46. 2012
..Asthma care in the United States remains suboptimal, indicating the need for continued improvements in patient management...
- Mometasone furoate/formoterol reduces asthma deteriorations and improves lung function
E O Meltzer
Allergy and Asthma Medical Group and Research Center, 9610 Granite Ridge Drive, Suite B, San Diego, CA 92123, USA
Eur Respir J 39:279-89. 2012
..MF/F 100/10 μg b.i.d. treatment showed greater clinical efficacy than its individual components or placebo; both components contributed to the efficacy of MF/F...
- Efficacy of fexofenadine versus desloratadine in suppressing histamine-induced wheal and flare
Eli O Meltzer
Allergy and Asthma Medical Group and Research Center, University of California at San Diego, San Diego, California, USA
Allergy Asthma Proc 28:67-73. 2007
..Fexofenadine HCl, 180 mg, was superior to desloratadine, 5 mg, in histamine-induced wheal-and-flare suppression, suggesting increased in vivo H1-receptor antagonist potency of fexofenadine versus desloratadine...
- Efficacy and safety of ciclesonide, 200 microg once daily, for the treatment of perennial allergic rhinitis
Eli O Meltzer
Allergy and Asthma Medical Group and Research Center, San Diego, California 92123 2661, USA
Ann Allergy Asthma Immunol 98:175-81. 2007
..Ciclesonide is an intranasal corticosteroid approved for the treatment of allergic rhinitis (AR)...
- Formulation considerations of intranasal corticosteroids for the treatment of allergic rhinitis
Eli O Meltzer
Allergy and Asthma Medical Group and Research Center, San Diego, California 92123 2661, USA
Ann Allergy Asthma Immunol 98:12-21. 2007
..To examine how various aspects of an intranasal corticosteroid (INS) formulation may influence the efficacy, tolerability, and patient preference and adherence to INS therapy...
- The efficacy and safety of mometasone furoate delivered via a dry powder inhaler for the treatment of asthma
Eli O Meltzer
Allergy and Asthma Medical Group and Research Center, University of California San Diego, 9610 Granite Ridge Drive, San Diego, CA 92123, USA
J Asthma 43:765-72. 2006
..In conclusion, mometasone furoate provides primary care and specialty physicians with a safe, effective, and convenient option to meet the challenges of asthma management...
- The systemic safety of inhaled corticosteroid therapy: a focus on ciclesonide
Eli O Meltzer
Allergy and Asthma Medical Group and Research Center, San Diego, California 92123, USA
Ann Allergy Asthma Immunol 97:149-57. 2006
..To review the potential systemic activity of ciclesonide and its active metabolite, desisobutyryl-ciclesonide, by evaluation of the effects on hypothalamic-pituitary-adrenal (HPA) axis function...
- Allergic rhinitis: managing the pediatric spectrum
Eli O Meltzer
Allergy and Asthma Medical Group and Research Center, San Diego, California 92123, USA
Allergy Asthma Proc 27:2-8. 2006
..Allergen immunotherapy can be a valuable adjunctive modality. Issues of compliance and convenience also are important considerations...
- Optimal management of community-acquired acute bacterial rhinosinusitis: the allergist's perspective
Eli O Meltzer
Allergy and Asthma Medical Group and Research Center, San Diego, CA 92123, USA
Ann Allergy Asthma Immunol 96:390-7. 2006
....
- Effect of desloratadine therapy on symptom scores and measures of nasal patency in seasonal allergic rhinitis: results of a single-center, placebo-controlled trial
Eli O Meltzer
Allergy and Asthma Medical Group and Research Center, San Diego, California 92123, USA
Ann Allergy Asthma Immunol 96:363-8. 2006
..Desloratadine reduces symptoms and maintains nasal airflow in patients with seasonal allergic rhinitis (SAR) during experimental allergen exposure...
- Safety and efficacy of olopatadine hydrochloride nasal spray for the treatment of seasonal allergic rhinitis
Eli O Meltzer
Allergy and Asthma Medical Group and Research Center, San Diego, California 92123, USA
Ann Allergy Asthma Immunol 95:600-6. 2005
..A nasal spray containing the antiallergy agent olopatadine hydrochloride is being developed for the treatment of seasonal allergic rhinitis (SAR)...
- Treating acute rhinosinusitis: comparing efficacy and safety of mometasone furoate nasal spray, amoxicillin, and placebo
Eli O Meltzer
Allergy and Asthma Medical Group and Research Center, San Diego, CA 92123, USA
J Allergy Clin Immunol 116:1289-95. 2005
..However, the efficacy of intranasal corticosteroid monotherapy for acute, uncomplicated rhinosinusitis is not established...
- Allergic rhinitis: the impact of discordant perspectives of patient and physician on treatment decisions
Eli O Meltzer
Allergy and Asthma Medical Group and Research Center, San Diego, California 92123, USA
Clin Ther 29:1428-40. 2007
..However, despite its high prevalence and significant impact on health-related quality of life (HRQOL) and productivity, AR may be undertreated. This might arise, in part, from the low priority given to the disease by physicians...
- Preferences of adult patients with allergic rhinitis for the sensory attributes of fluticasone furoate versus fluticasone propionate nasal sprays: a randomized, multicenter, double-blind, single-dose, crossover study
Eli O Meltzer
Allergy and Asthma Medical Group and Research Center, San Diego, California, USA
Clin Ther 30:271-9. 2008
..Product attributes influence patient preference for intranasal corticosteroid therapy in allergic rhinitis (AR)...
- Intranasal corticosteroids in the treatment of acute rhinosinusitis
Eli O Meltzer
Allergy and Asthma Medical Group and Research Center, San Diego, CA 92123, USA
Curr Allergy Asthma Rep 8:133-8. 2008
....
- The role of nasal corticosteroids in the treatment of rhinitis
Eli O Meltzer
Allergy and Asthma Medical Group and Research Center, 5776 Ruffin Road, San Diego, CA 92123, USA
Immunol Allergy Clin North Am 31:545-60. 2011
..Clinically, they have been shown to be the most effective class of nasal medications for treating allergic rhinitis and nonallergic rhinopathy, with no clear evidence that any specific INS is superior to others...
Rhinosinusitis diagnosis and management for the clinician: a synopsis of recent consensus guidelinesEli O Meltzer
Allergy and Asthma Medical Group and Research Center, 9610 Granite Ridge Dr, Ste B, San Diego, CA 92123, USA
Mayo Clin Proc 86:427-43. 2011
..Important and relevant data from MEDLINE-indexed articles published since the most recent guidelines were issued are also considered, and needs for future research are discussed...
- Mometasone furoate nasal spray for moderate-to-severe nasal congestion in subjects with seasonal allergic rhinitis
Eli O Meltzer
Allergy and Asthma Medical Group and Research Center, San Diego, California 92123, USA
Allergy Asthma Proc 32:159-67. 2011
..Adverse events were infrequent and localized; the most common (epistaxis and pharyngolaryngeal pain) occurred in 1.0% of MFNS patients. MFNS q.d. provides sustained relief for nasal congestion and other SAR symptoms...
- Use of the Asthma Control Questionnaire to predict future risk of asthma exacerbation
Eli O Meltzer
Allergy and Asthma Medical Group and Research Center, San Diego, Calif 92123, USA
J Allergy Clin Immunol 127:167-72. 2011
..Direct correlation of assessments of a validated composite measure such as the Asthma Control Questionnaire (ACQ) and risk of exacerbation has not been previously demonstrated in a randomized controlled trial...
- Comparison of patient preference for sensory attributes of fluticasone furoate or fluticasone propionate in adults with seasonal allergic rhinitis: a randomized, placebo-controlled, double-blind study
Eli O Meltzer
Allergy and Asthma Medical Group and Research Center, San Diego, California 92123, USA
Ann Allergy Asthma Immunol 104:331-8. 2010
..Intranasal corticosteroids are first-line treatment for moderate-to-severe seasonal allergic rhinitis (AR)...
- Burden of allergic rhinitis: results from the Pediatric Allergies in America survey
Eli O Meltzer
Allergy and Asthma Medical Group and Research Center, San Diego, CA 92123, USA
J Allergy Clin Immunol 124:S43-70. 2009
..Findings from this national survey have identified important challenges to the management of AR, suggesting that its burden on children in the United States has been significantly underestimated...
- Efficacy and safety evaluation of ciclesonide in mild-to-moderate persistent asthma previously treated with inhaled corticosteroids
Eli O Meltzer
Allergy and Asthma Medical Group and Research Center, San Diego, California, USA
Allergy Asthma Proc 30:293-303. 2009
..i.d. maintained asthma control in subjects with stable mild-to-moderate asthma previously treated with ICS or ICS/LABA, was well tolerated, and, in general, was better than CIC160 q.d. in maintaining disease control...
- Comparative study of sensory attributes of two antihistamine nasal sprays: olopatadine 0.6% and azelastine 0.1%
Eli O Meltzer
Allergy and Asthma Medical Group and Research Center, San Diego, CA 92123, USA
Allergy Asthma Proc 29:659-68. 2008
..This outcome could lead to greater patient compliance and improved treatment effect...
- Safety and tolerability of fluticasone furoate nasal spray once daily in paediatric patients aged 6-11 years with allergic rhinitis: subanalysis of three randomized, double-blind, placebo-controlled, multicentre studies
Eli O Meltzer
Allergy and Asthma Medical Group and Research Center, San Diego, California 92123, USA
Clin Drug Investig 29:79-86. 2009
....
- Efficacy and safety of once-daily fluticasone furoate nasal spray in children with seasonal allergic rhinitis treated for 2 wk
Eli O Meltzer
Allergy and Asthma Medical Group and Research Center, 9610 Granite Ridge Drive, Suite B, San Diego, CA 92123, USA
Pediatr Allergy Immunol 20:279-86. 2009
..Both doses of FF were well tolerated. These study results suggest that FF nasal spray administered once daily for 2 wk is well tolerated and effective for the treatment of SAR symptoms in children aged 2-11 yr...
- Evaluation of the optimal oral antihistamine for patients with allergic rhinitis
Eli O Meltzer
Allergy and Asthma Medical Group and Research Center, 9610 Granite Ridge Dr, Suite B, San Diego, CA 92123, USA
Mayo Clin Proc 80:1170-6. 2005
..Therefore, agents with broad therapeutic windows, based on both efficacy and safety, are expected to be more favorable; this therapeutic window should be understood by the primary care physician when prescribing a medication...
- An intranasal Syk-kinase inhibitor (R112) improves the symptoms of seasonal allergic rhinitis in a park environment
Eli O Meltzer
Allergy and Asthma Medical Group and Research Center, 9610 Granite Ridge Drive, Suite B, San Diego, CA 92123 2661, USA
J Allergy Clin Immunol 115:791-6. 2005
..R112 inhibits Syk kinase, a transducer of signaling through the Fcepsilon receptor of mast cells, blocking mast cell responses to allergic stimuli...
- Safety and efficacy of oral fexofenadine in children with seasonal allergic rhinitis--a pooled analysis of three studies
Eli O Meltzer
Allergy and Asthma Medical Group and Research Center, San Diego, CA, USA
Pediatr Allergy Immunol 15:253-60. 2004
..05). Fexofenadine, at doses of up to 60 mg b.i.d., is safe and non-sedating, and fexofenadine HCl 30 mg b.i.d. effectively reduces all seasonal allergic rhinitis symptoms in children aged 6-11 years...
- Clinical evidence for antileukotriene therapy in the management of allergic rhinitis
Eli O Meltzer
Allergy and Asthma Medical Group and Research Center, San Diego, California 92123, USA
Ann Allergy Asthma Immunol 88:23-9. 2002
..After reading this article, readers will have a greater understanding of these clinical findings and their implications for the management of allergic rhinitis...
- Efficacy and safety of low-dose fluticasone propionate compared with montelukast for maintenance treatment of persistent asthma
Eli O Meltzer
Allergy and Asthma Medical Group and Research Center, San Diego, CA 92123, USA
Mayo Clin Proc 77:437-45. 2002
..To compare the long-term effects of an inhaled corticosteroid with those of a leukotriene modifier on measures of clinical efficacy, subject preference, and safety in patients with persistent asthma...
- Allergic rhinitis, asthma, and rhinosinusitis: diseases of the integrated airway
Eli O Meltzer
Allergy and Asthma Medical Group and Research Center, University of California at San Diego, San Diego, CA 92123, USA
J Manag Care Pharm 10:310-7. 2004
..Controlling upper airway inflammation and symptoms among asthma patients may help improve health and economic outcomes...
- Intranasal mometasone furoate therapy for allergic rhinitis symptoms and rhinitis-disturbed sleep
Eli O Meltzer
Allergy and Asthma Medical Group and Research Center, San Diego, California 92123, USA
Ann Allergy Asthma Immunol 105:65-74. 2010
..Allergic rhinitis (AR) and related nasal congestion cause rhinitis-disturbed sleep (RDS). Intranasal corticosteroids reduce nasal congestion and improve sleep quality in AR but have not been extensively studied in RDS...
- Rhinosinusitis: Establishing definitions for clinical research and patient care
Eli O Meltzer
Allergy and Asthma Medical Group and Research Center, Department of Pediatrics, University of California, San Diego 92123, USA
Otolaryngol Head Neck Surg 131:S1-62. 2004
- Rhinosinusitis: establishing definitions for clinical research and patient care
Eli O Meltzer
Department of Pediatrics, Allergy and Asthma Medical Group and Research Center, 9610 Granite Ridge Drive, Suite B, San Diego, CA 92123, USA
J Allergy Clin Immunol 114:155-212. 2004
- Development of questionnaires to measure patient preferences for intranasal corticosteroids in patients with allergic rhinitis
Eli O Meltzer
Allergy and Asthma Medical Group and Research Center, San Diego, CA 92123, USA
Otolaryngol Head Neck Surg 132:197-207. 2005
..To develop a questionnaire to evaluate preferences for attributes of intranasal corticosteroids (INSs) in clinical trials with allergic rhinitis (AR) patients...
- Quality of life in adults and children with allergic rhinitis
E O Meltzer
Allergy and Asthma Medical Group and Research Center, San Diego, CA 92123, USA
J Allergy Clin Immunol 108:S45-53. 2001
..Agents that have troublesome adverse effects such as sedation can have a negative impact, whereas nonsedating antihistamines and intranasal cortico-steroids can significantly improve HRQL in patients of all ages with rhinitis...
- Physician perceptions of the treatment and management of allergic and nonallergic rhinitis
Eli O Meltzer
Allergy and Asthma Medical Group and Research Center, San Diego, California, USA
Allergy Asthma Proc 30:75-83. 2009
..This physician survey provides insight into perceptions of the impact of allergic rhinitis and nonallergic rhinitis on patients' quality of life and symptom severity...
- A preference evaluation study comparing the sensory attributes of mometasone furoate and fluticasone propionate nasal sprays by patients with allergic rhinitis
Eli O Meltzer
Allergy and Asthma Medical Group and Research Center, San Diego, CA 92123, USA
Treat Respir Med 4:289-96. 2005
..03). CONCLUSION: Several individual sensory attributes of MFNS were rated significantly superior to FPNS. Overall, based on the tested sensory attributes, patients preferred MFNS to FPNS therapy for the treatment of allergic rhinitis...
- Intranasal steroids: managing allergic rhinitis and tailoring treatment to patient preference
Eli O Meltzer
Allergy and Asthma Medical Group and Research Center, 9610 Granite Ridge Drive, Suite B, San Diego, CA 92123, USA
Allergy Asthma Proc 26:445-51. 2005
..The development of two new questionnaires, the Clinical Practice Patient Preference Questionnaire and the Clinical Trial Patient Preference Questionnaire, may prove useful in selecting the optimal treatment regimen for patients...
- Montelukast effectively treats the nighttime impact of seasonal allergic rhinitis
Eli O Meltzer
Allergy and Asthma Medical Group and Research Center, San Diego, CA 92109, USA
Am J Rhinol 19:591-8. 2005
..In these studies, montelukast significantly improved the NSS, a clinically relevant and valid measure in patients with SAR...
- Efficacy and safety of clemastine-pseudoephedrine-acetaminophen versus pseudoephedrine-acetaminophen in the treatment of seasonal allergic rhinitis in a 1-day, placebo-controlled park study
Eli O Meltzer
Allergy and Asthma Medical Group and Research Center, San Diego, California, USA
Ann Allergy Asthma Immunol 90:79-86. 2003
..Patients with allergic rhinitis have a wide range of symptoms that are often treated with oral combination products that contain antihistamines, decongestants, and analgesics...
- Safety and efficacy of olopatadine hydrochloride nasal spray 0.6% in pediatric subjects with allergic rhinitis
William E Berger
Department of Pediatrics, Division of Allergy and Immunology, University of California, Irvine, California, USA
Allergy Asthma Proc 30:612-23. 2009
..In subjects 6 to <12 years of age, OLO was superior to vehicle in the treatment of SAR. In subjects 2 to <12 years of age, OLO had an overall low rate of AEs and low systemic exposure...
- Effective dose range of mometasone furoate nasal spray in the treatment of acute rhinosinusitis
Anjuli S Nayak
Asthma and Allergy Research Associates, PC, Normal, Illinois 61761, USA
Ann Allergy Asthma Immunol 89:271-8. 2002
..Mometasone furoate nasal spray (MFNS) 400 microg, twice daily, as adjunctive treatment with oral antibiotic significantly improved symptoms of recurrent rhinosinusitis...
- Asthma management and environmental tobacco smoke exposure reduction in Latino children: a controlled trial
Melbourne F Hovell
Center for Behavioral Epidemiology and Community Health, Graduate School of Public Health, San Diego State University, San Diego, California 92123, USA
Pediatrics 110:946-56. 2002
..This study tested the efficacy of coaching to reduce environmental tobacco smoke (ETS) exposure among asthmatic Latino children...
- Triamcinolone acetonide and fluticasone propionate aqueous nasal sprays significantly improve nasal airflow in patients with seasonal allergic rhinitis
Eli O Meltzer
Allergy and Asthma Medical Group and Research Center, San Diego, California 92123, USA
Allergy Asthma Proc 25:53-8. 2004
..Weekly mean nPIFR scores indicated progressive improvement in nasal airflow with both treatments. Both TAA AQ and FP AQ were effective for improving nasal airflow as indicated by increases in nPIFR in patients with SAR...
- Rhinosinusitis: developing guidance for clinical trials
Eli O Meltzer
Allergy and Asthma Medical Group and Research Center and Department of Pediatrics, University of California, San Diego, USA
J Allergy Clin Immunol 118:S17-61. 2006
....
- Rhinosinusitis: Developing guidance for clinical trials
Eli O Meltzer
Allergy and Asthma Medical Group and Research Center Department of Pediatrics, University of California, San Diego, San Diego, California
Otolaryngol Head Neck Surg 135:S31-80. 2006
....
- Intranasal fluocortin butyl in patients with perennial rhinitis: a 12-month efficacy and safety study including nasal biopsy
H A Orgel
Allergy and Asthma Medical Group and Research Center, San Diego, Calif
J Allergy Clin Immunol 88:257-64. 1991
..There were few adverse effects. Mean plasma cortisol levels were normal before and after corticotropin stimulation at baseline and after 12 months of FCB therapy.(ABSTRACT TRUNCATED AT 250 WORDS)..
- The role of the immune system in the pathogenesis of asthma and an overview of the diagnosis, classification, and current approach to treating the disease
Eli O Meltzer
Allergy and Asthma Medical Group and Research Center, 9610 Granite Ridge Dr. #B, San Diego, CA 92123, USA
J Manag Care Pharm 9:8-13. 2003
..Choosing an appropriate delivery system for inhaled drug therapies can affect patient adherence and the effectiveness of therapy...
- Efficacy and patient satisfaction with cromolyn sodium nasal solution in the treatment of seasonal allergic rhinitis: a placebo-controlled study
Eli O Meltzer
Allergy and Asthma Medical Group and Research Center, San Diego, California 92123, USA
Clin Ther 24:942-52. 2002
..CONCLUSION: In this study, cromolyn sodium 4% nasal solution was well tolerated and effective, suggesting that it is suitable for OTC use in the treatment of seasonal allergic rhinitis...
- Increasing asthma knowledge and changing home environments for Latino families with asthmatic children
J A Jones
Center for Behavioral Epidemiology and Community Health, Graduate School of Public Health, San Diego State University, San Diego, CA, USA
Patient Educ Couns 42:67-79. 2001
..4 to 1.8, P < 0.001; mean number of controllers increased from 0.7 to 0.9, P < 0.001). The results support the value of asthma education and its importance in the national agenda to reduce health disparities among minorities...
- H1-antihistamines and the central nervous system
Michael J Welch
Allergy and Asthma Medical Group and Research Center, University of California, San Diego, San Diego, California, USA
Clin Allergy Immunol 17:337-88. 2002
....
- Latino children with asthma: rates and risks for medical care utilization
Jill Berg
UCLA School of Nursing, Los Angeles, California, USA
J Asthma 41:147-57. 2004
..Quality and monitored health care with optimization of asthma management could reduce costly acute care services...
- Psychometric validation of the rhinitis control assessment test: a brief patient-completed instrument for evaluating rhinitis symptom control
Michael Schatz
Kaiser Permanente, San Diego, California, USA
Ann Allergy Asthma Immunol 104:118-24. 2010
..Allergic rhinitis is common, but a validated tool for comprehensive assessment of disease control is not available...
- Introduction: Stuffy is also related to Sleepy and Grumpy--the link between rhinitis and sleep-disordered breathing
Eli O Meltzer
Allergy and Asthma Medical Group and Research Center, Department of Pediatrics, University of California-San Diego, San Diego, CA, USA
J Allergy Clin Immunol 114:S133-4. 2004
- Addition of ibuprofen to pseudoephedrine and chlorpheniramine in the treatment of seasonal allergic rhinitis
Eli O Meltzer
Allergy and Asthma Medical Group and Research Center, San Diego, California, USA
Ann Allergy Asthma Immunol 93:452-9. 2004
..Furthermore, the superior efficacy of the lower dose of the triple combination allowed for a decrease in the incidence of adverse effects...
- Pharmacologic rationale for treating allergic and nonallergic rhinitis
Alexander N Greiner
Allergy and Asthma Medical Group and Research Center and the University of California San Diego School of Medicine, San Diego, CA 92123, USA
J Allergy Clin Immunol 118:985-98. 2006
..Furthermore, appropriate stepped-up, stepped-down pharmacotherapeutic algorithms are described for the various forms of rhinitis...
- The relationships of rhinitis and asthma
Eli O Meltzer
Allergy and Asthma Medical Group and Research Center, 9610 Granite Ridge Drive, Suite B, San Diego, CA 92123, USA
Allergy Asthma Proc 26:336-40. 2005
..To clarify the relationships between upper and lower airway disorders and to establish the potential benefits of an integrated airways management approach, additional studies are warranted...
- Sleep, quality of life, and productivity impact of nasal symptoms in the United States: findings from the Burden of Rhinitis in America survey
Eli O Meltzer
Allergy and Asthma Medical Group and Research Center, San Diego, California, USA
Allergy Asthma Proc 30:244-54. 2009
..05). Individuals who suffer from AR symptoms experience a substantial burden on their ability to sleep, quality of life, cognitive function, and school/workplace productivity...
- Impact of azelastine nasal spray on symptoms and quality of life compared with cetirizine oral tablets in patients with seasonal allergic rhinitis
William Berger
Southern California Research, Mission Viejo 92691, USA
Ann Allergy Asthma Immunol 97:375-81. 2006
....
- Efficacy and safety of fluticasone propionate/salmeterol 250/50 mcg Diskus administered once daily
Edward M Kerwin
Clinical Research Institute of Southern Oregon, Medford, OR 97504, USA
Respir Med 102:495-504. 2008
..The once daily administration of an ICS/LABA may be a treatment option for some patients...
- Efficacy of montelukast during the allergy season in patients with chronic asthma and seasonal aeroallergen sensitivity
William W Busse
Department of Medicine, University of Wisconsin Medical School, Madison, Wisconsin 53792, USA
Ann Allergy Asthma Immunol 96:60-8. 2006
..Montelukast has proven efficacy in the treatment of chronic asthma and seasonal allergic rhinitis, but it has not been evaluated in the subpopulation of asthmatic patients with seasonal asthma symptoms...
- Efficacy of desloratadine, 5 mg, compared with fexofenadine, 180 mg, in patients with symptomatic seasonal allergic rhinitis
William E Berger
Allergy and Asthma Associates of Southern California, Mission Viejo, California 92691, USA
Allergy Asthma Proc 27:214-23. 2006
..All treatments were well tolerated. Desloratadine, 5 mg, and fexofenadine, 180 mg, provide comparable efficacy and tolerability in the treatment of SAR. Both treatments are significantly more effective than placebo...
- Use of intranasal cromolyn sodium for allergic rhinitis
Paul H Ratner
Sylvana Research Associates and Department of Pediatrics, University of Texas Health Science Center, San Antonio, USA
Mayo Clin Proc 77:350-4. 2002
..Intranasal cromolyn has an excellent safety record, is available as an over-the-counter medication, and has been proved to be efficacious in patients with allergic rhinitis...
- Histamine skin test reactivity following single and multiple doses of azelastine nasal spray in patients with seasonal allergic rhinitis
David S Pearlman
Colorado Allergy and Asthma Centers, PC, Denver, Colorado 80230, USA
Ann Allergy Asthma Immunol 91:258-62. 2003
..To determine whether azelastine nasal spray suppresses the dermal response to epicutaneous histamine in allergic patients and the duration of suppression after azelastine use is discontinued...
- Intranasal fluticasone propionate is effective for perennial nonallergic rhinitis with or without eosinophilia
D Robert Webb
Allergy and Asthma Research Associates, Kirkland, Washington 98034, USA
Ann Allergy Asthma Immunol 88:385-90. 2002
..Objective: To evaluate the efficacy of intranasal fluticasone propionate (FP) in the treatment of patients with perennial nonallergic rhinitis, with and without nasal eosinophilia...
- Antibiotics and nasal steroids for acute sinusitis
Eli O Meltzer
JAMA 299:1422-3; author reply 1423. 2008
- Fexofenadine is efficacious and safe in children (aged 6-11 years) with seasonal allergic rhinitis
Ulrich Wahn
Department of Pediatric Pneumology and Immunology, University Children's Hospital, Berlin, Germany
J Allergy Clin Immunol 111:763-9. 2003
..CONCLUSION: The efficacy and safety of the H(1)-antihistamine fexofenadine has been confirmed in this multicenter, multinational study of children aged 6 to 11 years with seasonal allergic rhinitis...
- Requirements for medications commonly used in the treatment of allergic rhinitis. European Academy of Allergy and Clinical Immunology (EAACI), Allergic Rhinitis and its Impact on Asthma (ARIA)
Jean Bousquet
Allergy 58:192-7. 2003
- Emerging therapeutic strategies for asthma management
Sean D Sullivan
Pharmaceutical Outcomes Research and Policy Program, Department of Pharmacy, University of Washington, 1959 NE Pacific Ave, Box 357630, Seattle, WA 98195, USA
J Manag Care Pharm 9:14-21. 2003
..The describe the mechanisms of action of and clinical experience to date with novel asthma drug therapies...
- No growth suppression in children treated with the maximum recommended dose of fluticasone propionate aqueous nasal spray for one year
David B Allen
University of Wisconsin Children's Hospital, 600 Highland Ave, Madison, Wisconsin 53792, USA
Allergy Asthma Proc 23:407-13. 2002
....
- Comprehensive report of the efficacy, safety, quality of life, and work impact of Olopatadine 0.6% and Olopatadine 0.4% treatment in patients with seasonal allergic rhinitis
Carol J Fairchild
Alcon Laboratories, Inc, 6201 South Freeway, Fort Worth, Texas 76134, USA
Allergy Asthma Proc 28:716-23. 2007
..This analysis indicates that Olo is a safe and effective intranasal treatment and is associated with significant improvement in QoL and ability to perform work and conduct usual activities of SAR patients...
- Effect of mometasone furoate nasal spray on quality of life of patients with acute rhinosinusitis
Claus Bachert
Ear, Nose and Throat Department, University Hospital, Ghent, Belgium
Rhinology 45:190-6. 2007
..Treatment with MFNS 200 g b.i.d. is associated with a significant improvement in HRQoL compared with placebo in patients with acute, uncomplicated rhinosinusitis...
- A questionnaire to measure quality of life in adults with nocturnal allergic rhinoconjunctivitis
Elizabeth F Juniper
Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
J Allergy Clin Immunol 111:484-90. 2003
....
- Development and validation of the Congestion Quantifier seven-item test (CQ7): a screening tool for nasal congestion
Donald E Stull
United BioSource Corporation, Bethesda, MD 20814, USA
Value Health 10:457-65. 2007
..Nevertheless, there is no short screening tool designed specifically to identify congestion that can help patients make decisions about seeking treatment...
- Exploring new frontiers in asthma management for optimal therapeutic and economic outcomes
Sean D Sullivan
Pharmaceutical Outcomes Research and Policy Program, Department of Pharmacy, University of Washington, 1959 NE Pacific Ave, Box 357630, Seattle, WA 98195, USA
J Manag Care Pharm 9:2. 2003
