A double-blind, placebo-controlled study of quetiapine and paroxetine as monotherapy in adults with bipolar depression (EMBOLDEN II)Susan L McElroy
Lindner Center of HOPE Research Institute, Mason, OH 45040, USA
J Clin Psychiatry 71:163-74. 2010
..The aim of this study was to evaluate the efficacy and tolerability of quetiapine and paroxetine monotherapy for major depression in bipolar disorder...
A placebo-controlled pilot study of the novel opioid receptor antagonist ALKS-33 in binge eating disorderSusan L McElroy
Lindner Center of HOPE, Research Institute, Mason, OH 45040, USA
Int J Eat Disord 46:239-45. 2013
..To assess preliminarily the effectiveness of a novel opioid antagonist, ALKS-33, in binge eating disorder (BED)...
Obesity in bipolar disorder: an overviewSusan L McElroy
Lindner Center of HOPE, 4075 Old Western Road, Mason, OH 45040, USA
Curr Psychiatry Rep 14:650-8. 2012
..Bariatric surgery may be an option for carefully selected patients. Greater research into the theoretical underpinnings and clinical management of the BD-obesity connection is needed...
Current pharmacotherapy options for bulimia nervosa and binge eating disorderSusan L McElroy
Lindner Center of HOPE, 4075 Old Western Row Road, Mason, OH 45040, USA
Expert Opin Pharmacother 13:2015-26. 2012
..Single RCTs suggest zonisamide and atomoxetine may be effective in BED. Combination therapy may be required for optimal outcomes. It is not yet known whether the binge eating of BN and BED respond similarly to pharmacotherapy...
A randomized, placebo-controlled study of zonisamide to prevent olanzapine-associated weight gainSusan L McElroy
Lindner Center of HOPE, Mason, OH 45040, USA
J Clin Psychopharmacol 32:165-72. 2012
..02). Zonisamide was effective for mitigating weight gain in patients with bipolar disorder or schizophrenia initiating treatment with olanzapine but was associated with cognitive impairment as an adverse event...
Role of antiepileptic drugs in the management of eating disordersSusan L McElroy
Lindner Center of HOPE, Mason, Ohio 45050, USA
CNS Drugs 23:139-56. 2009
..g. mood) or neurological (e.g. seizure) disorder; otherwise, both agents, particularly valproate, are associated with weight gain. In conclusion, AEDs have an emerging role in the management of some eating disorders...
Obesity in patients with severe mental illness: overview and managementSusan L McElroy
Lindner Center of HOPE, 4075 Old Western Row Rd, Mason, OH 45040, USA
J Clin Psychiatry 70:12-21. 2009
..Severe mental illness with obesity must be viewed as 2 chronic illnesses that each require long-term management...
Placebo-controlled study of quetiapine monotherapy in ambulatory bipolar spectrum disorder with moderate-to-severe hypomania or mild maniaSusan L McElroy
Lindner Center of HOPE, Mason, Ohio 45040, USA
J Affect Disord 124:157-63. 2010
..There are no randomized, placebo-controlled data for quetiapine in outpatients with bipolar spectrum disorder (ambulatory BSD) and moderate-to-severe hypomanic or mild manic symptoms (hypomania/mild mania)...
Randomized, double-blind, placebo-controlled study of divalproex extended release loading monotherapy in ambulatory bipolar spectrum disorder patients with moderate-to-severe hypomania or mild maniaSusan L McElroy
4075 Old Western Row Road, Mason, OH 45040, USA
J Clin Psychiatry 71:557-65. 2010
..To determine whether divalproex extended release (ER) would be effective in outpatients with DSM-IV-TR-diagnosed ambulatory bipolar spectrum disorder (BSD) and moderate-to-severe hypomanic or mild manic symptoms (hypomania/mild mania)...
Prevalence and correlates of eating disorders in 875 patients with bipolar disorderSusan L McElroy
Craig and Frances Lindner Center of HOPE, Mason, OH 45040, USA
J Affect Disord 128:191-8. 2011
..Relatively little is known about the co-occurrence of bipolar and eating disorders. We therefore assessed the prevalence and clinical correlates of eating disorders in 875 patients with bipolar disorder...
Acamprosate in the treatment of binge eating disorder: a placebo-controlled trialSusan L McElroy
Lindner Center of HOPE, Research Institute, 4075 Old Western Row Road, Mason, OH45040, USA
Int J Eat Disord 44:81-90. 2011
..To assess preliminarily the effectiveness of acamprosate in binge eating disorder (BED)...
Therapeutic potential of new second generation antipsychotics for major depressive disorderSusan L McElroy
Lindner Center of HOPE, 4075 Old Western Row Road, Mason, Ohio 45040, USA
Expert Opin Investig Drugs 19:1527-44. 2010
..Aripiprazole, olanzapine and quetiapine each have indications that involve MDD. Growing evidence indicates that quetiapine, evaluated as the extended release formulation, is efficacious as monotherapy for nonpsychotic MDD...
A 24-week, randomized, controlled trial of adjunctive sibutramine versus topiramate in the treatment of weight gain in overweight or obese patients with bipolar disordersSusan L McElroy
Psychopharmacology Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
Bipolar Disord 9:426-34. 2007
..The objective of this study was to compare sibutramine and topiramate as adjunctive treatments for psychotropic-associated weight gain in overweight or obese outpatients with BD...
Open-label aripiprazole in the treatment of acute bipolar depression: a prospective pilot trialSusan L McElroy
Psychopharmacology Research Program, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States
J Affect Disord 101:275-81. 2007
..Increasing evidence indicates that some second-generation antipsychotics are efficacious in bipolar depression, but there are few data on this illness for the novel agent aripiprazole...
Open-label adjunctive zonisamide in the treatment of bipolar disorders: a prospective trialSusan L McElroy
Psychopharmacology Research Program, Department of Psychiatry, PO Box 670559, University of Cincinnati College of Medicine, 231 Albert Sabin Way, Cincinnati, OH 45267, USA
J Clin Psychiatry 66:617-24. 2005
..The response of 62 outpatients with DSM-IV bipolar disorders to open-label adjunctive zonisamide was evaluated in a prospective 8-week acute trial, followed by a 48-week continuation trial, conducted from June 2001 through May 2002...
Topiramate in the long-term treatment of binge-eating disorder associated with obesitySusan L McElroy
Psychopharmacology Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0559, USA
J Clin Psychiatry 65:1463-9. 2004
..This study assessed the long-term effectiveness and tolerability of topiramate in binge-eating disorder (BED) with obesity...
Citalopram in the treatment of binge-eating disorder: a placebo-controlled trialSusan L McElroy
Division of Psychopharmacology Research and Eating Disorders, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0559, USA
J Clin Psychiatry 64:807-13. 2003
..Citalopram is a highly selective serotonin reuptake inhibitor antidepressant. The purpose of this study was to assess the efficacy and safety of citalopram in the treatment of binge-eating disorder...
Are mood disorders and obesity related? A review for the mental health professionalSusan L McElroy
Psychopharmacology Research and Eating Disorders and Obesity Research and Treatment Programs, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0559, USA
J Clin Psychiatry 65:634-51, quiz 730. 2004
..We reviewed evidence regarding a possible relationship between mood disorders and obesity to better inform mental health professionals about their overlap...
Double-blind, randomized, placebo-controlled trials of ethyl-eicosapentanoate in the treatment of bipolar depression and rapid cycling bipolar disorderPaul E Keck
Psychopharmacology Research Program, Department of Psychiatry, University of Cincinnati College of Medicine and the Mental Health Care Line, Cincinnati, Ohio 45267 0559, USA
Biol Psychiatry 60:1020-2. 2006
..The results of pilot trials suggest that omega-3 fatty acids may have efficacy in the treatment of mood symptoms in bipolar disorder...
Zonisamide in the treatment of binge eating disorder with obesity: a randomized controlled trialSusan L McElroy
Psychopharmacology Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, OH 45267 0559, USA
J Clin Psychiatry 67:1897-906. 2006
..Binge eating disorder (BED) is associated with obesity. Zonisamide is a novel antiepileptic drug associated with weight loss. The purpose of this study was to evaluate zonisa-mide in the treatment of BED associated with obesity...
Lithium augmentation of topiramate for bipolar disorder with comorbid binge eating disorder and obesityRenu Kotwal
Department of Psychiatry, Psychopharmacology Research Program, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
Hum Psychopharmacol 21:425-31. 2006
..To evaluate the effectiveness of lithium augmentation of topiramate on mood symptoms, binge eating behavior, and body weight in obese bipolar patients with binge eating disorder (BED) seeking weight management...
Pharmacologic treatment considerations in co-occurring bipolar and anxiety disordersPaul E Keck
Psychopharmacology Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, OH 45267 0559, USA
J Clin Psychiatry 67:8-15. 2006
..Anxiety disorders are among the most commonly co-occurring psychiatric syndromes with bipolar disorder. The presence of co-occurring anxiety disorders has important prognostic and treatment implications...
Comorbidity of bipolar and eating disorders: distinct or related disorders with shared dysregulations?Susan L McElroy
Psychopharmacology Research Program, University of Cincinnati College of Medicine, P O Box 670559, 231 Bethesda Avenue, Cincinnati, OH 45267 0559, USA
J Affect Disord 86:107-27. 2005
..The co-occurrence of bipolar and eating disorders, though of major clinical and public health importance, remains relatively unexamined...
Analyses of treatment-emergent mania with olanzapine/fluoxetine combination in the treatment of bipolar depressionPaul E Keck
Psychopharmacology Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA
J Clin Psychiatry 66:611-6. 2005
..These subanalyses compare treatment-emergent mania rates in bipolar I depressed patients treated with olanzapine, placebo, or olanzapine/fluoxetine combination...
Topiramate in the treatment of binge eating disorder associated with obesity: a randomized, placebo-controlled trialSusan L McElroy
Division of Psychopharmacology Research, Department of Psychiatry, University of Cincinnati College of Medicine, OH 45267 0559, USA
Am J Psychiatry 160:255-61. 2003
..Binge eating disorder is associated with obesity. Topiramate is an antiepileptic agent associated with weight loss. The objective of this study was to evaluate topiramate in the treatment of binge eating disorder associated with obesity...
Correlates of overweight and obesity in 644 patients with bipolar disorderSusan L McElroy
Stanley Foundation Bipolar Treatment Outcome Network, Department of Psychiatry, University of Cincinnati College of Medicine, Ohio 45267-0559, USA
J Clin Psychiatry 63:207-13. 2002
....
High-dose escitalopram in the treatment of binge-eating disorder with obesity: a placebo-controlled monotherapy trialAnna I Guerdjikova
Division of Psychopharmacology Research, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0559, USA
Hum Psychopharmacol 23:1-11. 2008
..The purpose of this study was to evaluate the efficacy and safety of high-dose escitalopram in the treatment of binge-eating disorder (BED) associated with obesity...
New approaches in managing bipolar depressionPaul E Keck
Program Psychopharmacology Research, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0559, USA
J Clin Psychiatry 64:13-8. 2003
....
Atomoxetine in the treatment of binge-eating disorder: a randomized placebo-controlled trialSusan L McElroy
Psychopharmacology Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, OH 45267 0559, USA
J Clin Psychiatry 68:390-8. 2007
..Binge-eating disorder (BED) is associated with obesity. Atomoxetine is a highly selective norepinephrine reuptake inhibitor associated with weight loss. The purpose of this study was to evaluate atomoxetine in the treatment of BED...
Psychosis in bipolar disorder: phenomenology and impact on morbidity and course of illnessPaul E Keck
Department of Psychiatry, University of Cincinnati College of Medicine, OH 45267-0559, USA
Compr Psychiatry 44:263-9. 2003
..The lack of observable prognostic impact may have been, in part, due to the relatively high morbidity and poor functional outcome of a substantial portion of the total cohort...
Characterizing impulsivity in maniaStephen M Strakowski
Division of Bipolar Disorders Research, Universtiy of Cincinnati College of Medicine, Cincinnati, OH, USA
Bipolar Disord 11:41-51. 2009
....
Psychiatric and legal features of 113 men convicted of sexual offensesNeal W Dunsieth
Center for the Study of Criminal Behavior, Department of Psychiatry, University of Cincinnati College of Medicine, 231 Albert Sabin Way, Cincinnati, OH 45267-0559, USA
J Clin Psychiatry 65:293-300. 2004
..On the basis of our findings, we assert that sex offenders should be carefully evaluated for the presence of mental illness and that sex offender management programs should have a capacity for psychiatric treatment...
Psychopathology in children of bipolar parentsManpreet K Singh
Division of Bipolar Disorders Research, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
J Affect Disord 102:131-6. 2007
..Few studies have examined the psychopathological profiles of child offspring of bipolar parents. Such investigations are useful as a first step to identifying potential prodromal manifestations of bipolar disorder...
Topiramate for the treatment of binge eating disorder associated with obesity: a placebo-controlled studySusan L McElroy
Psychopharmacology Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0559, USA
Biol Psychiatry 61:1039-48. 2007
..The current investigation evaluated the safety and efficacy of topiramate in a multicenter, placebo-controlled trial...
Response of recurrent binge eating and weight gain to topiramate in patients with binge eating disorder after bariatric surgeryAnna I Guerdjikova
Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
Obes Surg 15:273-7. 2005
..The effectiveness of topiramate was evaluated in the treatment of recurrent binge eating and weight gain in patients with binge eating disorder (BED) and obesity who had undergone initially successful bariatric surgery...
Psychiatric and metabolic characteristics of childhood versus adult-onset obesity in patients seeking weight managementAnna I Guerdjikova
Psychopharmacology Program, Department of Psychiatry, University of Cincinnati College of Medicine, 231 Albert Sabin Way, Cincinnati, OH 45267 0559, USA
Eat Behav 8:266-76. 2007
..Early recognition and attention to eating and mood dysregulation, including, but not limited to binge eating disorder and bulimia nervosa, in some persons, might help reduce their lifetime risk for obesity...
Comorbidity of eating disorders with bipolar disorder and treatment implicationsSusan L McElroy
Psychopharmacology Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, 231 Albert Sabin Way, Cincinnati, OH 45267, USA
Bipolar Disord 8:686-95. 2006
..To review the scientific evidence examining the comorbidity among eating disorders and bipolar disorder (BD)...
Lamotrigine in the treatment of binge-eating disorder with obesity: a randomized, placebo-controlled monotherapy trialAnna I Guerdjikova
Department of Psychiatry, University of Cincinnati College of Medicine, Lindner Center of HOPE, Mason, Ohio 45040, USA
Int Clin Psychopharmacol 24:150-8. 2009
..As a result of an exceptionally high placebo response, it is likely that for efficacy measures except for body weight and metabolic indices, the study was incapable of detecting potentially clinically important drug-placebo difference...
Sodium oxybate in the treatment of binge eating disorder: an open-label, prospective studySusan L McElroy
Research Institute, Lindner Center of HOPE, Mason, Ohio, USA
Int J Eat Disord 44:262-8. 2011
..To assess preliminarily the effectiveness of sodium oxybate in binge eating disorder...
A placebo-controlled, randomized trial of fluoxetine in the treatment of binge-eating disorderLesley M Arnold
Women s Health Research Program, Department of Psychiatry, University of Cincinnati Medical Center, Cincinnati, Ohio, USA
J Clin Psychiatry 63:1028-33. 2002
..The purpose of this study was to assess the efficacy and safety of fluoxetine in the treatment of binge-eating disorder...
Olanzapine in the treatment of pathological gambling: a negative randomized placebo-controlled trialSusan L McElroy
Psychopharmacology Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0559, USA
J Clin Psychiatry 69:433-40. 2008
..Olanzapine is a second-generation antipsychotic with mood-stabilizing properties and antagonistic activity at several dopamine receptors. The purpose of this study was to evaluate olanzapine in the treatment of pathological gambling...
Diagnosing and treating comorbid (complicated) bipolar disorderSusan L McElroy
Department of Psychiatry, University of Cincinnati College of Medicine, OH 45267, USA
J Clin Psychiatry 65:35-44. 2004
....
Bipolar disorders: special diagnostic and treatment considerations in womenSusan L McElroy
Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA
CNS Spectr 9:5-18. 2004
..Further studies are needed on gestational timing and exposure to mood-stabilizing agents, especially newer agents recently approved or currently being considered for the treatment of bipolar disorder...
Zonisamide in the treatment of binge-eating disorder: an open-label, prospective trialSusan L McElroy
Division of Clinical Neuroscience, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA
J Clin Psychiatry 65:50-6. 2004
..It commonly co-occurs with obesity. Zonisamide is a novel antiepileptic drug associated with weight loss. The purpose of this study was to preliminarily assess zonisamide in the treatment of binge-eating disorder...
Relationship of open acute mania treatment to blinded maintenance outcome in bipolar I disorderSusan L McElroy
Psychopharmacology Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
J Affect Disord 107:127-33. 2008
..No published studies have statistically evaluated the relationship between the outcomes in maintenance treatment and the principal acute agent...
Duloxetine in the treatment of binge eating disorder with depressive disorders: a placebo-controlled trialAnna I Guerdjikova
Lindner Center of HOPE, Mason, OH, USA
Int J Eat Disord 45:281-9. 2012
..This study evaluated duloxetine in the treatment of binge eating disorder (BED) with comorbid current depressive disorders...
Bipolar disorder, obesity, and pharmacotherapy-associated weight gainPaul E Keck
Division of Clinical Neuroscience, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0559, USA
J Clin Psychiatry 64:1426-35. 2003
..This risk may be due to factors associated with the illness itself and/or with medications used to treat bipolar disorder...
Emotional eating and emotional eating alternatives in subjects undergoing bariatric surgeryAnna I Guerdjikova
Psychopharmacology Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
Obes Surg 17:1091-6. 2007
..The purpose of this study was to characterize emotional eating and its alternatives in obese patients undergoing bariatric surgery...
A 52-week, open-label continuation study of lamotrigine in the treatment of bipolar depressionSusan L McElroy
Psychopharmacology Research Program, University of Cincinnati College of Medicine, 231 Bethesda Avenue, Cincinnati, OH 45267 0559, USA
J Clin Psychiatry 65:204-10. 2004
..Lamotrigine has demonstrated efficacy for the acute treatment of depression in bipolar I patients in a placebo-controlled, monotherapy study. We describe the results of a 52-week, open-label continuation of that trial...
A randomized, placebo-controlled study of adjunctive ramelteon in ambulatory bipolar I disorder with manic symptoms and sleep disturbanceSusan L McElroy
aLindner Center of HOPE, Mason, Ohio and University of Cincinnati College of Medicine, Cincinnati, Ohio bDepartment of Psychiatry and Health Behavior, Medical College of Georgia, Augusta, Georgia, USA
Int Clin Psychopharmacol 26:48-53. 2011
..Further studies of ramelteon in subgroups of bipolar patients with sleep disturbance, including those with depression or euthymia, seem indicated...
Aripiprazole: a partial dopamine D2 receptor agonist antipsychoticPaul E Keck
Psychopharmacology Research Program, Department of Psychiatry, University of Cincinnati College of Medicine and General Clinical Research Center, Mental Health Service Line, Cincinnati Veterans Affairs Medical Center, Cincinnati, Ohio, USA
Expert Opin Investig Drugs 12:655-62. 2003
..In addition, aripiprazole was not associated with significant weight gain or QTc prolongation in both acute and long-term treatment trials...
Carbamazepine and valproate in the maintenance treatment of bipolar disorderPaul E Keck
Department of Psychiatry, University of Cincinnati College of Medicine, Ohio 45267 0559, USA
J Clin Psychiatry 63:13-7. 2002
..We reviewed the available data from randomized clinical trials of these agents in bipolar disorder to assess their efficacy and tolerability in the maintenance phase of illness management...
Medical management of obesity associated with mental disordersShishuka Malhotra
Biological Psychiatry Program, University of Cincinnati College of Medicine, Ohio 45267-0559, USA
J Clin Psychiatry 63:24-32. 2002
..In this review, we aim to improve understanding of the relationship between obesity and mental illness and provide practical clinical guidelines for the management of obesity associated with mental disorders...
Binge eating disorder in elderly individualsAnna I Guerdjikova
Lindner Center of HOPE, Mason, OH, USA
Int J Eat Disord 45:905-8. 2012
..To preliminarily describe the clinical features of elderly individuals with binge eating disorder (BED)...
Antidepressants and suicidal behavior in bipolar disorderSusan L McElroy
Psychopharmacology Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
Bipolar Disord 8:596-617. 2006
....
Divalproex in the treatment of bipolar disorderPaul E Keck
Department of Psychiatry, University of Cincinnati College of Medicine, 231 Albert Sabin Way, PO Box 670559, Cincinnati, OH 45267, USA
Psychopharmacol Bull 37:67-73. 2003
..The results of randomized, controlled trials of valproate in the treatment of bipolar disorder are reviewed along with their implications for clinical practice...
Clinical pharmacodynamics and pharmacokinetics of antimanic and mood-stabilizing medicationsPaul E Keck
Department of Psychiatry, University of Cincinnati College of Medicine, Ohio 45267 0559, USA
J Clin Psychiatry 63:3-11. 2002
..We reviewed the clinical pharmacodynamics and pharmacokinetics of these agents to provide a summary of these properties relevant to clinical practice...
Preliminary evidence for gender-specific effects of topiramate as a potential aid to smoking cessationRobert M Anthenelli
Tri State Tobacco and Alcohol Research Center, Cincinnati Veterans Affairs Medical Center, Cincinnati, OH 45220, USA
Addiction 103:687-94. 2008
....
Severity of bipolarity in hospitalized manic adolescents with history of stimulant or antidepressant treatmentCesar A Soutullo
University of Cincinnati, Department of Psychiatry, Biological Psychiatry and Psychotic and Bipolar Disorders Research Programs, PO Box 670559, 231 Bethesda Avenue, Cincinnati, OH 45267 0559, USA
J Affect Disord 70:323-7. 2002
..Childhood bipolarity (BP) and ADHD frequently co-occur, these children often receive stimulants...
Advances in the pharmacologic treatment of bipolar depressionPaul E Keck
Division of Psychopharmacology Research, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267-0559, USA
Biol Psychiatry 53:671-9. 2003
....
Redefining mood stabilizationPaul E Keck
Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
J Affect Disord 73:163-9. 2003
..No available agent meets the criteria for a comprehensive mood-stabilizer, although lithium comes the closest...
Binge eating disorder pharmacotherapy clinical trails--who is left out?Anna I Guerdjikova
Department of Psychiatry, Lindner Center of HOPE, Mason, OH 45267 0559, USA
Eur Eat Disord Rev 17:101-8. 2009
..This report examined the characteristics of subjects interested in binge eating disorder (BED) pharmacotherapy trails who were ineligible for participation...
N-acetylcysteine in bulimia nervosa - open-label trialAnna I Guerdjikova
Lindner Center of HOPE, Mason, OH 45040, USA
Eat Behav 14:87-9. 2013
..In this trial, NAC was ineffective in BN and was associated with a high discontinuation rate...
Pharmacological management of binge eating disorder: current and emerging treatment optionsSusan L McElroy
Lindner Center of HOPE, Mason, and Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH, USA
Ther Clin Risk Manag 8:219-41. 2012
..We conclude by summarizing these data, discussing the role of pharmacotherapy in the BED treatment armamentarium, and suggesting future areas for research...
Bulimia nervosa presenting as rectal purging and rectal prolapse: case report and literature reviewAnna I Guerdjikova
Lindner Center of HOPE, Mason, Ohio 45040, USA
Int J Eat Disord 45:456-9. 2012
..Further research into the relationship between eating disorders, rectal purging, and gastrointestinal dysfunction is called for...