Kevin W McCairn

Summary

Publications

  1. doi request reprint The neurophysiological correlates of motor tics following focal striatal disinhibition
    Kevin W McCairn
    The Leslie and Suzan Gonda Brain Research Center, Bar Ilan University, Israel
    Brain 132:2125-38. 2009
  2. doi request reprint Common therapeutic mechanisms of pallidal deep brain stimulation for hypo- and hyperkinetic movement disorders
    Kevin W McCairn
    Systems Neuroscience and Movement Disorders Laboratory, Korea Brain Research Institute, Daegu, Republic of Korea
    J Neurophysiol 114:2090-104. 2015
  3. doi request reprint A Primary Role for Nucleus Accumbens and Related Limbic Network in Vocal Tics
    Kevin W McCairn
    Systems Neuroscience and Movement Disorders Laboratory, Korea Brain Research Institute, Daegu 701 300, South Korea Laboratory for Symbolic Cognitive Development, RIKEN Brain Science Institute, Wako, Saitama 351 0198, Japan Systems Neuroscience Section, Primate Research Institute, Kyoto University, Inuyama, Aichi 484 8506, Japan Laboratory of Cognitive and Behavioral Neuroscience, Division of Biomedical Science, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki 305 8577, Japan Electronic address
    Neuron 89:300-7. 2016
  4. pmc Pallidal stimulation suppresses pathological dysrhythmia in the parkinsonian motor cortex
    Kevin W McCairn
    Department of Neurological Surgery, University of California, San Francisco, California Department of Biological Sciences, Milton Keynes, The Open University, Buckinghamshire, United Kingdom and
    J Neurophysiol 113:2537-48. 2015
  5. doi request reprint Pharmacological animal models of tic disorders
    Kevin W McCairn
    Systems Neuroscience Division, Primate Research Institute, Kyoto University, Inuyama, Aichi, Japan Electronic address
    Int Rev Neurobiol 112:179-209. 2013
  6. doi request reprint Deep brain stimulation reduces Tic-related neural activity via temporal locking with stimulus pulses
    Kevin W McCairn
    Unit on Neural Systems and Behavior, Okinawa Institute of Science and Technology, Onna Son, Okinawa 904 0495, Japan
    J Neurosci 33:6581-93. 2013
  7. doi request reprint Global dysrhythmia of cerebro-basal ganglia-cerebellar networks underlies motor tics following striatal disinhibition
    Kevin W McCairn
    Unit on Neural Systems and Behavior, Okinawa Institute of Science and Technology, Onna Son, Okinawa 904 0495, Japan
    J Neurosci 33:697-708. 2013
  8. doi request reprint High-frequency pallidal stimulation eliminates tic-related neuronal activity in a nonhuman primate model of Tourette syndrome
    Kevin W McCairn
    Unit on Neural Systems and Behavior, Okinawa Institute of Science and Technology, Onna Son, Okinawa, Japan
    Neuroreport 23:206-10. 2012
  9. pmc Motor cortex stimulation: mild transient benefit in a primate model of Parkinson disease
    Alex K Wu
    Department of Neurological Surgery, University of California, San Francisco, California, USA
    J Neurosurg 106:695-700. 2007

Collaborators

Detail Information

Publications9

  1. doi request reprint The neurophysiological correlates of motor tics following focal striatal disinhibition
    Kevin W McCairn
    The Leslie and Suzan Gonda Brain Research Center, Bar Ilan University, Israel
    Brain 132:2125-38. 2009
    ..The neuronal changes observed during tic formation may provide valuable insights into the underlying mechanism of tic disorders, as well as into basic information processing in the cortico-basal ganglia loop...
  2. doi request reprint Common therapeutic mechanisms of pallidal deep brain stimulation for hypo- and hyperkinetic movement disorders
    Kevin W McCairn
    Systems Neuroscience and Movement Disorders Laboratory, Korea Brain Research Institute, Daegu, Republic of Korea
    J Neurophysiol 114:2090-104. 2015
    ....
  3. doi request reprint A Primary Role for Nucleus Accumbens and Related Limbic Network in Vocal Tics
    Kevin W McCairn
    Systems Neuroscience and Movement Disorders Laboratory, Korea Brain Research Institute, Daegu 701 300, South Korea Laboratory for Symbolic Cognitive Development, RIKEN Brain Science Institute, Wako, Saitama 351 0198, Japan Systems Neuroscience Section, Primate Research Institute, Kyoto University, Inuyama, Aichi 484 8506, Japan Laboratory of Cognitive and Behavioral Neuroscience, Division of Biomedical Science, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki 305 8577, Japan Electronic address
    Neuron 89:300-7. 2016
    ..We propose that vocal tics emerge as a consequence of dysrhythmic alpha coupling between critical nodes in the limbic and motor networks. VIDEO ABSTRACT. ..
  4. pmc Pallidal stimulation suppresses pathological dysrhythmia in the parkinsonian motor cortex
    Kevin W McCairn
    Department of Neurological Surgery, University of California, San Francisco, California Department of Biological Sciences, Milton Keynes, The Open University, Buckinghamshire, United Kingdom and
    J Neurophysiol 113:2537-48. 2015
    ..The results are consistent with the hypothesis that suppression of both pathological, beta oscillations and synchronous activity throughout the cortico-basal ganglia network is a major therapeutic mechanism of GPi-DBS. ..
  5. doi request reprint Pharmacological animal models of tic disorders
    Kevin W McCairn
    Systems Neuroscience Division, Primate Research Institute, Kyoto University, Inuyama, Aichi, Japan Electronic address
    Int Rev Neurobiol 112:179-209. 2013
    ....
  6. doi request reprint Deep brain stimulation reduces Tic-related neural activity via temporal locking with stimulus pulses
    Kevin W McCairn
    Unit on Neural Systems and Behavior, Okinawa Institute of Science and Technology, Onna Son, Okinawa 904 0495, Japan
    J Neurosci 33:6581-93. 2013
    ....
  7. doi request reprint Global dysrhythmia of cerebro-basal ganglia-cerebellar networks underlies motor tics following striatal disinhibition
    Kevin W McCairn
    Unit on Neural Systems and Behavior, Okinawa Institute of Science and Technology, Onna Son, Okinawa 904 0495, Japan
    J Neurosci 33:697-708. 2013
    ..These findings indicate that tic-generating networks in basal ganglia mediated tic disorders extend beyond classical cerebro-basal ganglia circuits, leading to global network dysrhythmia including cerebellar circuits...
  8. doi request reprint High-frequency pallidal stimulation eliminates tic-related neuronal activity in a nonhuman primate model of Tourette syndrome
    Kevin W McCairn
    Unit on Neural Systems and Behavior, Okinawa Institute of Science and Technology, Onna Son, Okinawa, Japan
    Neuroreport 23:206-10. 2012
    ..This finding supports the premise that deep brain stimulation targeted to the globus pallidus internus could be a viable treatment option for Tourette syndrome, and the use of pallidal stimulation for motor tics warrants further study...
  9. pmc Motor cortex stimulation: mild transient benefit in a primate model of Parkinson disease
    Alex K Wu
    Department of Neurological Surgery, University of California, San Francisco, California, USA
    J Neurosurg 106:695-700. 2007
    ....