Percutaneous renal graft biopsy: a clinical, laboratory and pathological analysisM Mazzali
Departamento de Clinica Medica, Faculdade de Ciências Médicas Universidade Estadual de Campinas, Brazil
Sao Paulo Med J 117:57-62. 1999
..Renal allograft biopsies have been used as a good method for monitoring the evolution of kidney transplants for at least 20 years. Histological analysis permits differential diagnosis of the causes of allograft dysfunction to be made...
Elevated uric acid increases blood pressure in the rat by a novel crystal-independent mechanismM Mazzali
Division of Nephrology, University of Washington Medical Center, Seattle, USA
Hypertension 38:1101-6. 2001
..In conclusion, mild hyperuricemia causes hypertension and renal injury in the rat via a crystal-independent mechanism, with stimulation of the renin-angiotensin system and inhibition of neuronal NO synthase...
Post-cyclosporine-mediated hypertension and nephropathy: amelioration by vascular endothelial growth factorD H Kang
Division of Nephrology, Department of Medicine, University of Washington, Seattle, Washington 98195, USA
Am J Physiol Renal Physiol 280:F727-36. 2001
..The vascular protective effect of VEGF may be due to the improvement of arteriolopathy. Angiogenic growth factors may represent a novel strategy for treating CsA-associated hypertension and renal disease...
Impaired angiogenesis in the remnant kidney model: II. Vascular endothelial growth factor administration reduces renal fibrosis and stabilizes renal functionD H Kang
Division of Nephrology, University of Washington, Seattle, WA, USA
J Am Soc Nephrol 12:1448-57. 2001
..58 +/- 3.45%, VEGF versus vehicle, P < 0.01). In conclusion, VEGF treatment reduces fibrosis and stabilizes renal function in the RK model. The use of angiogenic factors may represent a new approach to the treatment of kidney disease...
Hyperuricemia exacerbates chronic cyclosporine nephropathyM Mazzali
Division of Nephrology, University of Washington Medical Center, Seattle 98185, USA
Transplantation 71:900-5. 2001
..The mechanism does not involve intrarenal uric acid crystal deposition and appears to involve activation of the renin angiotensin system and inhibition of intrarenal nitric oxide production...
Impaired angiogenesis in the remnant kidney model: I. Potential role of vascular endothelial growth factor and thrombospondin-1D H Kang
Division of Nephrology, University of Washington, Seattle, WA, USA
J Am Soc Nephrol 12:1434-47. 2001
..The impaired angiogenesis may be mediated by alterations in the renal expression of TSP-1 and VEGF, with the latter being regulated by macrophage-associated cytokines...
Hypokalemia induces renal injury and alterations in vasoactive mediators that favor salt sensitivityS I Suga
Division of Nephrology, University of Washington Medical Center, Seattle, WA 98195, USA
Am J Physiol Renal Physiol 281:F620-9. 2001
..These alterations may predispose the animals to salt-sensitive hypertension that manifests despite normalization of the serum K+...
Delayed graft function in renal transplant recipients: risk factors and impact on 1-year graft function: a single center analysisE J M Bronzatto
Division of Nephrology, Department of Medicine, State University of Campinas UNICAMP, Campinas, Brazil
Transplant Proc 41:849-51. 2009
..In this study we sought to identify among a group of recipients of kidneys from deceased donors, the incidence, risk factors, and impacts on patient and graft survivals of DGF...
Involvement of macrophage migration inhibitory factor (MIF) in experimental uric acid nephropathyY G Kim
Division of Nephrology, University of Washington Medical Center, Seattle, USA
Mol Med 6:837-48. 2000
..We hypothesized that uric acid crystal deposition may induce granuloma formation by stimulating local expression of macrophage migration inhibitory factor (MIF), which is a known mediator of delayed type hypersensitivity (DTH)...
Tuberculosis in renal transplant recipients: a Brazilian center registryJ P S Guida
Division of Nephrology, Department of Medicine, School of Medical Sciences, State University of Campinas DCM FCM UNICAMP, Campinas, Brazil
Transplant Proc 41:883-4. 2009
..TB represents the major cause of morbidity and mortality in the world, mainly in underdeveloped countries. The aim of this study was to analyze the incidence of TB and its presentation among renal transplant recipients over 20 years...
Changes in serological markers of hepatitis B virus after renal transplantationC Urbini Dos Santos
Division of Nephrology, Department of Medicine, FCM, State University of Campinas UNICAMP, Sao Paulo, Brazil
Transplant Proc 40:749-51. 2008
..In summary, prevalence of HBV in kidney transplant patients was 4.2%. Immunosuppression after renal transplantation in HBV infection led to an increased risk of liver complications and changes in HBV serological status...
Posttransplant diabetes mellitus: incidence and risk factorsF Cr Mazali
Division of Nephrology, State University of Campinas, UNICAMP, Sao Paulo, Brazil
Transplant Proc 40:764-6. 2008
..Posttransplant diabetes mellitus (PTDM) is common post transplantation and is associated with tacrolimus (TAC) and steroid therapy. The aim of the present study was to analyze the incidences of PTDM and associated risk factors...
Skin malignancies in renal transplant recipients: a Brazilian center registryP M Falsarella
Division of Nephrology, Department of Medicine, School of Medical Sciences State University of Campinas, UNICAMP, Campinas, Sao Paulo, Brazil
Transplant Proc 40:767-8. 2008
..The aim of the present study was to analyze the incidence of skin malignancies in a setting of renal transplant recipients over 20 years follow-up...
Systemic lupus erythematosus after renal transplantation: is complement a good marker for graft survival?A L Signori Baracat
Division of Nephrology, Department of Medicine, School of Medical Sciences, State University of Campinas, UNICAMP, Brazil
Transplant Proc 40:746-8. 2008
..Renal transplantation is considered a safe procedure for patients with systemic lupus erythematosus (SLE). However, the recurrence of disease and its impact on graft survival remains controversial...
Nutritional status and body composition in patients early after renal transplantationM C A S Netto
Specialization in Nutrition in Nephrology, Division of Nephrology, School of Medical Sciences, State University of Campinas, UNICAMP, Campinas, Sao Paulo, Brazil
Transplant Proc 44:2366-8. 2012
..After renal transplantation recovery in nutritional status occurs during the first year. We assessed the changes in nutritional status after transplantation in 145 transplant recipients (94 males, 51 females)...
Urine cytology as a screening method for polyoma virus active infectionR L S Santos
Division of Nephrology, Department of Medicine, DCM FCM UNICAMP, Sao Paulo, Brazil
Transplant Proc 36:899-901. 2004
..The absence of PVN in this group may be attributed to the low doses of immunosuppressive drugs in the late posttransplant transplant period, but also to the unknown incidence of polyoma virus infection in Brazil...