Christopher A Maxwell

Summary

Publications

  1. pmc Genomic imbalance of HMMR/RHAMM regulates the sensitivity and response of malignant peripheral nerve sheath tumour cells to aurora kinase inhibition
    Pooja Mohan
    Department of Pediatrics, Child and Family Research Institute, University of British Columbia, Vancouver, British Columbia, Canada
    Oncotarget 4:80-93. 2013
  2. pmc Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer
    Christopher A Maxwell
    Translational Research Laboratory, Catalan Institute of Oncology, Bellvitge Biomedical Research Institute IDIBELL, L Hospitalet, Catalonia, Spain
    PLoS Biol 9:e1001199. 2011
  3. pmc Exploring the link between MORF4L1 and risk of breast cancer
    Griselda Martrat
    Translational Research Laboratory, Catalan Institute of Oncology, Bellvitge Institute for Biomedical Research IDIBELL, Gran Via 199, L Hospitalet del Llobregat 08908, Spain
    Breast Cancer Res 13:R40. 2011
  4. ncbi request reprint Tubers from patients with tuberous sclerosis complex are characterized by changes in microtubule biology through ROCK2 signalling
    Isidre Ferrer
    Institute of Neuropathology, University Hospital Bellvitge, University of Barcelona, Bellvitge Institute for Biomedical Research IDIBELL, CIBERNED, L Hospitalet del Llobregat, Barcelona, Catalonia, Spain
    J Pathol 233:247-57. 2014
  5. ncbi request reprint TACC3-TSC2 maintains nuclear envelope structure and controls cell division
    Laia Gómez-Baldó
    Translational Research Laboratory, Catalan Institute of Oncology, Bellvitge Biomedical Research Institute, Barcelona, Spain
    Cell Cycle 9:1143-55. 2010
  6. pmc The cytoskeletal protein RHAMM and ERK1/2 activity maintain the pluripotency of murine embryonic stem cells
    Jihong Jiang
    Department of Pediatrics, Child and Family Research Institute, University of British Columbia, Vancouver, British Columbia, Canada
    PLoS ONE 8:e73548. 2013
  7. doi request reprint Multifunctional proteins bridge mitosis with motility and cancer with inflammation and arthritis
    Jihong Jiang
    Department of Pediatrics, Child and Family Research Institute, University of British Columbia, Vancouver, Canada
    ScientificWorldJournal 10:1244-57. 2010
  8. pmc Biological convergence of cancer signatures
    Xavier Sole
    Bioinformatics and Biostatistics Unit, Catalan Institute of Oncology, IDIBELL, L Hospitalet, Barcelona, Spain
    PLoS ONE 4:e4544. 2009

Detail Information

Publications8

  1. pmc Genomic imbalance of HMMR/RHAMM regulates the sensitivity and response of malignant peripheral nerve sheath tumour cells to aurora kinase inhibition
    Pooja Mohan
    Department of Pediatrics, Child and Family Research Institute, University of British Columbia, Vancouver, British Columbia, Canada
    Oncotarget 4:80-93. 2013
    ..Collectively, our data indicate that AURKA is a rationale therapeutic target for MPNST and tumour cell responses to AKI, which include differentiation, are modulated by the abundance of HMMR/RHAMM...
  2. pmc Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer
    Christopher A Maxwell
    Translational Research Laboratory, Catalan Institute of Oncology, Bellvitge Biomedical Research Institute IDIBELL, L Hospitalet, Catalonia, Spain
    PLoS Biol 9:e1001199. 2011
    ....
  3. pmc Exploring the link between MORF4L1 and risk of breast cancer
    Griselda Martrat
    Translational Research Laboratory, Catalan Institute of Oncology, Bellvitge Institute for Biomedical Research IDIBELL, Gran Via 199, L Hospitalet del Llobregat 08908, Spain
    Breast Cancer Res 13:R40. 2011
    ..To gain deeper insight into this pathway and its influence on cancer risk, we searched for novel components through protein physical interaction screens...
  4. ncbi request reprint Tubers from patients with tuberous sclerosis complex are characterized by changes in microtubule biology through ROCK2 signalling
    Isidre Ferrer
    Institute of Neuropathology, University Hospital Bellvitge, University of Barcelona, Bellvitge Institute for Biomedical Research IDIBELL, CIBERNED, L Hospitalet del Llobregat, Barcelona, Catalonia, Spain
    J Pathol 233:247-57. 2014
    ..Copyright © 2014 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd. ..
  5. ncbi request reprint TACC3-TSC2 maintains nuclear envelope structure and controls cell division
    Laia Gómez-Baldó
    Translational Research Laboratory, Catalan Institute of Oncology, Bellvitge Biomedical Research Institute, Barcelona, Spain
    Cell Cycle 9:1143-55. 2010
    ....
  6. pmc The cytoskeletal protein RHAMM and ERK1/2 activity maintain the pluripotency of murine embryonic stem cells
    Jihong Jiang
    Department of Pediatrics, Child and Family Research Institute, University of British Columbia, Vancouver, British Columbia, Canada
    PLoS ONE 8:e73548. 2013
    ..Thus, RHAMM is not found on the cell-surface of embryonic stem cells, but it is required to maintain pluripotency and its dominant mechanism of action is through the modulation of signal transduction pathways at microtubules. ..
  7. doi request reprint Multifunctional proteins bridge mitosis with motility and cancer with inflammation and arthritis
    Jihong Jiang
    Department of Pediatrics, Child and Family Research Institute, University of British Columbia, Vancouver, Canada
    ScientificWorldJournal 10:1244-57. 2010
    ..Our goal is to highlight a number of commonalities among these multifunctional proteins for better understanding of their putative roles in tumor initiation, inflammation, arthritis, and cancer...
  8. pmc Biological convergence of cancer signatures
    Xavier Sole
    Bioinformatics and Biostatistics Unit, Catalan Institute of Oncology, IDIBELL, L Hospitalet, Barcelona, Spain
    PLoS ONE 4:e4544. 2009
    ..Examination of additional, independent, cancer datasets corroborated our observations. This study proposes a comprehensive strategy for interpreting cancer signatures that reveals common design principles and systems-level properties...