Dimitrios Matthaiou

Summary

Publications

  1. ncbi The role of aminoglycosides in combination with a beta-lactam for the treatment of bacterial endocarditis: a meta-analysis of comparative trials
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    J Antimicrob Chemother 57:639-47. 2006
  2. doi Pandrug-resistant Klebsiella pneumoniae, Pseudomonas aeruginosa and Acinetobacter baumannii infections: characteristics and outcome in a series of 28 patients
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, 9 Neapoleos Street, 151 23 Marousi, Athens, Greece
    Int J Antimicrob Agents 32:450-4. 2008
  3. doi Short- versus long-course antibiotic therapy for acute pyelonephritis in adolescents and adults: a meta-analysis of randomized controlled trials
    Kleoniki G Kyriakidou
    Alfa Institute of Biomedical Sciences, Marousi, Greece
    Clin Ther 30:1859-68. 2008
  4. doi Therapeutic options for Burkholderia cepacia infections beyond co-trimoxazole: a systematic review of the clinical evidence
    Sophia G Avgeri
    Alfa Institute of Biomedical Sciences AIBS, 9 Neapoleos Street, 151 23 Marousi, Athens, Greece
    Int J Antimicrob Agents 33:394-404. 2009
  5. doi Effect of meteorological variables on the incidence of lower urinary tract infections
    M E Falagas
    Alfa Institute of Biomedical Sciences AIBS, 9 Neapoleos Street, 151 23, Marousi, Athens, Greece
    Eur J Clin Microbiol Infect Dis 28:709-12. 2009
  6. pmc Effectiveness and safety of short vs. long duration of antibiotic therapy for acute bacterial sinusitis: a meta-analysis of randomized trials
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences, 9 Neapoleos Street, Marousi, Greece
    Br J Clin Pharmacol 67:161-71. 2009
  7. doi Meta-analysis on surgical infections
    Dimitrios K Matthaiou
    Alfa Institute of Biomedical Sciences, Marousi, Athens, Greece
    Infect Dis Clin North Am 23:405-30. 2009
  8. ncbi Trimethoprim-sulfamethoxazole for methicillin-resistant Staphylococcus aureus: a forgotten alternative?
    G Pappas
    Institute of Continuing Medical Education of Ioannina, Greece
    J Chemother 21:115-26. 2009
  9. ncbi Adjunctive dexamethasone therapy for bacterial meningitis in adults: a meta-analysis of randomized controlled trials
    K Z Vardakas
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    Eur J Neurol 16:662-73. 2009
  10. doi Incidence, characteristics and outcomes of patients with severe community acquired-MRSA pneumonia
    K Z Vardakas
    Alfa Institute of Biomedical Sciences, 9 Neapoleos Street, 151 23 Marousi, Greece
    Eur Respir J 34:1148-58. 2009

Collaborators

Detail Information

Publications33

  1. ncbi The role of aminoglycosides in combination with a beta-lactam for the treatment of bacterial endocarditis: a meta-analysis of comparative trials
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    J Antimicrob Chemother 57:639-47. 2006
    ..The addition of an aminoglycoside to a beta-lactam for the treatment of patients with infective endocarditis has been supported by data from laboratory and animal studies...
  2. doi Pandrug-resistant Klebsiella pneumoniae, Pseudomonas aeruginosa and Acinetobacter baumannii infections: characteristics and outcome in a series of 28 patients
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, 9 Neapoleos Street, 151 23 Marousi, Athens, Greece
    Int J Antimicrob Agents 32:450-4. 2008
    ..Antibiotics that are ineffective in vitro may prove life-saving for some of these patients, especially combination regimens containing colistin...
  3. doi Short- versus long-course antibiotic therapy for acute pyelonephritis in adolescents and adults: a meta-analysis of randomized controlled trials
    Kleoniki G Kyriakidou
    Alfa Institute of Biomedical Sciences, Marousi, Greece
    Clin Ther 30:1859-68. 2008
    ..A potential reduction in the duration of the administered antibiotic regimens could contribute to avoiding further development of antimicrobial resistance...
  4. doi Therapeutic options for Burkholderia cepacia infections beyond co-trimoxazole: a systematic review of the clinical evidence
    Sophia G Avgeri
    Alfa Institute of Biomedical Sciences AIBS, 9 Neapoleos Street, 151 23 Marousi, Athens, Greece
    Int J Antimicrob Agents 33:394-404. 2009
    ..However, the available clinical data are not sufficient and further clinical experience is required to clarify the appropriateness of these antibiotics for BCC infections...
  5. doi Effect of meteorological variables on the incidence of lower urinary tract infections
    M E Falagas
    Alfa Institute of Biomedical Sciences AIBS, 9 Neapoleos Street, 151 23, Marousi, Athens, Greece
    Eur J Clin Microbiol Infect Dis 28:709-12. 2009
    ..The awareness of this association may facilitate preventive public health strategies. [corrected]..
  6. pmc Effectiveness and safety of short vs. long duration of antibiotic therapy for acute bacterial sinusitis: a meta-analysis of randomized trials
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences, 9 Neapoleos Street, Marousi, Greece
    Br J Clin Pharmacol 67:161-71. 2009
    ....
  7. doi Meta-analysis on surgical infections
    Dimitrios K Matthaiou
    Alfa Institute of Biomedical Sciences, Marousi, Athens, Greece
    Infect Dis Clin North Am 23:405-30. 2009
    ..Meta-analyses focusing exclusively on surgical infections, reporting data on mortality as a primary outcome, and comparing different antibiotic regimens for the treatment of surgical infections should be conducted...
  8. ncbi Trimethoprim-sulfamethoxazole for methicillin-resistant Staphylococcus aureus: a forgotten alternative?
    G Pappas
    Institute of Continuing Medical Education of Ioannina, Greece
    J Chemother 21:115-26. 2009
    ..SXT may represent a cost-effective alternative weapon against MRSA. Its utility against this increasingly threatening pathogen need clarification through further clinical trials...
  9. ncbi Adjunctive dexamethasone therapy for bacterial meningitis in adults: a meta-analysis of randomized controlled trials
    K Z Vardakas
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    Eur J Neurol 16:662-73. 2009
    ..Large studies are needed to clarify the role of the duration of symptoms, disease severity, and antibiotic administration before the initiation of treatment with dexamethasone on modifying the outcomes...
  10. doi Incidence, characteristics and outcomes of patients with severe community acquired-MRSA pneumonia
    K Z Vardakas
    Alfa Institute of Biomedical Sciences, 9 Neapoleos Street, 151 23 Marousi, Greece
    Eur Respir J 34:1148-58. 2009
    ..001), shock (p = 0.001), acute respiratory distress syndrome (p = 0.001), influenza like symptoms (p = 0.008), disseminated intravascular coagulation (p = 0.042) and rash (p = 0.04) were the factors associated with death...
  11. ncbi Comparison of community-acquired pneumonia due to methicillin-resistant and methicillin-susceptible Staphylococcus aureus producing the Panton-Valentine leukocidin
    K Z Vardakas
    Alfa Institute of Biomedical Sciences, Athens, Greece
    Int J Tuberc Lung Dis 13:1476-85. 2009
    ..aureus (MSSA) community-acquired pneumonia (CAP) producing the Panton-Valentine leukocidin (PVL)...
  12. doi Colistin therapy for microbiologically documented multidrug-resistant Gram-negative bacterial infections: a retrospective cohort study of 258 patients
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, 9 Neapoleos Street, 15 123 Marousi, Athens, Greece
    Int J Antimicrob Agents 35:194-9. 2010
    ..The findings of the largest cohort study to date on i.v. colistin show that colistin is a valuable antibiotic with acceptable nephrotoxicity and considerable effectiveness that depends on the daily dosage and infection site...
  13. doi Resistance to polymyxins: Mechanisms, frequency and treatment options
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    Drug Resist Updat 13:132-8. 2010
    ..Polymyxin combination regimens, tigecycline and fosfomycin may be useful options for the treatment of polymyxin-resistant gram-negative infections...
  14. ncbi Short- versus long-course antibacterial therapy for community-acquired pneumonia : a meta-analysis
    George Dimopoulos
    Alfa Institute of Biomedical Sciences AIBS, Athens, GreeceDepartment of Critical Care, Attikon University Hospital, University of Athens, Athens, Greece
    Drugs 68:1841-54. 2008
    ..The evidence for traditionally recommended 7- to 14-day duration of antibacterial therapy for community-acquired pneumonia (CAP) is not well established...
  15. doi Citrobacter infections in a general hospital: characteristics and outcomes
    G Samonis
    Department of Internal Medicine, University Hospital of Heraklion, Heraklion, Greece
    Eur J Clin Microbiol Infect Dis 28:61-8. 2009
    ..02). The isolation of Citrobacter species, although rather infrequent, was clinically relevant in the great majority of cases. Further attention should be paid to these pathogens...
  16. ncbi Effectiveness and safety of short-course vs long-course antibiotic therapy for group a beta hemolytic streptococcal tonsillopharyngitis: a meta-analysis of randomized trials
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences, 9 Neapoleos St, 151 23 Marousi, Athens, Greece
    Mayo Clin Proc 83:880-9. 2008
    ..To evaluate the effectiveness and safety of short-course antibiotic treatment of group A beta-hemolytic streptococcal (GAS) tonsillopharyngitis...
  17. ncbi Ciprofloxacin/metronidazole versus beta-lactam-based treatment of intra-abdominal infections: a meta-analysis of comparative trials
    Dimitrios K Matthaiou
    Alfa Institute of Biomedical Sciences AIBS, 9 Neapoleos Street, 15123 Marousi, Athens, Greece
    Int J Antimicrob Agents 28:159-65. 2006
    ....
  18. ncbi Vaginal mesh infection due to Bacteroides melaninogenicus: a case report of another emerging foreign body related infection
    Stavros Athanasiou
    Alfa Institute of Biomedical Sciences, Athens, Greece
    Scand J Infect Dis 38:1108-10. 2006
    ..However, the patient continued to avoid intercourse due to severe dyspareunia. Vaginal mesh-related infections represent an emerging type of infection that may complicate reconstructive surgery in patients with pelvic organ prolapse...
  19. ncbi Fluoroquinolones vs beta-lactams for empirical treatment of immunocompetent patients with skin and soft tissue infections: a meta-analysis of randomized controlled trials
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, 9 Neapoleos St, 151 23 Marousi, Athens, Greece
    Mayo Clin Proc 81:1553-66. 2006
    ..To compare the effectiveness and safety of fluoroquinolones with beta-lactams in the treatment of patients with skin and soft tissue infections (SSTIs)...
  20. ncbi Systematic review: fluoroquinolones for the treatment of intra-abdominal surgical infections
    M E Falagas
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    Aliment Pharmacol Ther 25:123-31. 2007
    ..Intra-abdominal infections result in substantial morbidity and mortality. Fluoroquinolones are among the various regimens that are used for the treatment of these infections...
  21. ncbi Meta-analysis: randomized controlled trials of clindamycin/aminoglycoside vs. beta-lactam monotherapy for the treatment of intra-abdominal infections
    M E Falagas
    Alfa Institute of Biomedical Sciences, Athens, Greece
    Aliment Pharmacol Ther 25:537-56. 2007
    ..To compare the effectiveness and safety of clindamycin/aminoglycoside with broad-spectrum beta-lactam monotherapy in patients with intra-abdominal infections by performing a meta-analysis of randomized controlled trials (RCTs)...
  22. ncbi Heteroresistance: a concern of increasing clinical significance?
    M E Falagas
    Clin Microbiol Infect 14:101-4. 2008
    ..Further studies are required to evaluate the clinical implications of heteroresistance in an era in which rates of antimicrobial resistance are increasing alarmingly worldwide...
  23. doi Statins for infection and sepsis: a systematic review of the clinical evidence
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    J Antimicrob Chemother 61:774-85. 2008
    ..Statins are currently used for hyperlipidaemia control and considered useful for protection from cardiovascular events. In addition, there is increasing evidence for the potential use of statins in preventing and treating infections...
  24. doi Meta-analysis: ertapenem for complicated intra-abdominal infections
    M E Falagas
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    Aliment Pharmacol Ther 27:919-31. 2008
    ..Ertapenem is a new member of the carbapenem class of antibiotics, with a favourable pharmacokinetic profile, but a narrower spectrum of antimicrobial activity, compared with older representatives of this class...
  25. doi Use of ACE inhibitors and risk of community-acquired pneumonia: a review
    Petros I Rafailidis
    Alfa Institute of Biomedical Sciences, 9 Neapoleos Street, 151 23 Marousi, Greece
    Eur J Clin Pharmacol 64:565-73. 2008
    ....
  26. pmc Albendazole versus praziquantel in the treatment of neurocysticercosis: a meta-analysis of comparative trials
    Dimitrios K Matthaiou
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    PLoS Negl Trop Dis 2:e194. 2008
    ..We investigated the role of albendazole and praziquantel in the treatment of patients with parenchymal neurocysticercosis by performing a meta-analysis of comparative trials of their effectiveness and safety...
  27. doi Risk factors associated with the isolation of colistin-resistant gram-negative bacteria: a matched case-control study
    Dimitrios K Matthaiou
    Alfa Institute of Biomedical Sciences, Athens, Greece
    Crit Care Med 36:807-11. 2008
    ..We aimed to investigate the potential risk factors for the isolation of colistin-resistant Klebsiella pneumoniae, Acinetobacter baumannii, and Pseudomonas aeruginosa from hospitalized patients...
  28. doi Fluoroquinolones versus beta-lactam based regimens for the treatment of osteomyelitis: a meta-analysis of randomized controlled trials
    Eirinaios M Karamanis
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    Spine (Phila Pa 1976) 33:E297-304. 2008
    ..A meta-analysis of randomized control trials...
  29. ncbi Short- versus long-duration antimicrobial treatment for exacerbations of chronic bronchitis: a meta-analysis
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    J Antimicrob Chemother 62:442-50. 2008
    ..The aim of this study was to evaluate the comparative effectiveness and safety of short (5 days) and long (7 or 10 days) duration antimicrobial treatment of patients with acute exacerbations of chronic bronchitis (AECB)...
  30. doi Therapeutic options for Stenotrophomonas maltophilia infections beyond co-trimoxazole: a systematic review
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences, Athens, Greece
    J Antimicrob Chemother 62:889-94. 2008
    ..We sought to evaluate the available clinical evidence regarding potentially effective alternative antibiotics for the treatment of S. maltophilia infections...
  31. doi An ESICM systematic review and meta-analysis of procalcitonin-guided antibiotic therapy algorithms in adult critically ill patients
    Dimitrios K Matthaiou
    Department of Internal Medicine, G Gennimatas General Hospital, 41 Ethnikis Amynis Str, 546 35 Thessaloniki, Greece
    Intensive Care Med 38:940-9. 2012
    ..We sought to perform a systematic review and meta-analysis of procalcitonin(PCT)-guided antibiotic therapy algorithms for critically ill adult patients...