P P Mathur

Summary

Publications

  1. ncbi request reprint Effect of lindane on testicular antioxidant system and steroidogenic enzymes in adult rats
    R Sujatha
    School of Life Sciences, Pondicherry University, India
    Asian J Androl 3:135-8. 2001
  2. ncbi request reprint Effect of lindane on antioxidant enzymes in epididymis and epididymal sperm of adult rats
    K C Chitra
    School of Life Sciences, Pondicherry University, India
    Asian J Androl 3:205-8. 2001
  3. ncbi request reprint Effect of methoxychlor on antioxidant system of goat epididymal sperm in vitro
    B Gangadharan
    School of Life Sciences, Pondicherry University, India
    Asian J Androl 3:285-8. 2001
  4. ncbi request reprint The effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin on the antioxidant system in mitochondrial and microsomal fractions of rat testis
    C Latchoumycandane
    School of Life Sciences, Pondicherry University, 605 014, Pondicherry, India
    Toxicology 171:127-35. 2002
  5. ncbi request reprint The effect of methoxychlor on the epididymal antioxidant system of adult rats
    C Latchoumycandane
    School of Life Sciences, Pondicherry University, 605 014, India
    Reprod Toxicol 16:161-72. 2002
  6. ncbi request reprint Bisphenol A induces reactive oxygen species generation in the liver of male rats
    V Bindhumol
    School of Life Sciences, Pondicherry University, Pondicherry 605 014, India
    Toxicology 188:117-24. 2003
  7. ncbi request reprint Induction of oxidative stress by bisphenol A in the epididymal sperm of rats
    K C Chitra
    School of Life Sciences, Pondicherry University, Pondicherry 605 014, India
    Toxicology 185:119-27. 2003
  8. ncbi request reprint Effect of nonylphenol on the antioxidant system in epididymal sperm of rats
    K C Chitra
    School of Life Sciences, Pondicherry University, Pondicherry 605 014, India
    Arch Toxicol 76:545-51. 2002
  9. doi request reprint Effect of restraint stress on 2,3,7,8 tetrachloro dibenzo-p-dioxin induced testicular and epididymal toxicity in rats
    S Dhanabalan
    Department of Biochemistry and Molecular Biology, School of Life Sciences, Pondicherry University, Pondicherry, India
    Hum Exp Toxicol 30:567-78. 2011
  10. ncbi request reprint Effect of methoxychlor on the antioxidant system in mitochondrial and microsome-rich fractions of rat testis
    C Latchoumycandane
    School of Life Sciences, Pondicherry University, Pondicherry 605 014, India
    Toxicology 176:67-75. 2002

Collaborators

  • E O Farombi
  • S Vaithinathan
  • C Latchoumycandane
  • K C Chitra
  • B Saradha
  • R Jubendradass
  • S Dhanabalan
  • Shereen Cynthia D'Cruz
  • S C D'cruz
  • I A Adedara
  • Oli Sarkar
  • R Sujatha
  • V Bindhumol
  • M Arul Murugan
  • B Gangadharan
  • S Judith Amala Rani
  • P Latha
  • K Ramachandra Rao
  • Bindu Gangadharan
  • M A Murugan

Detail Information

Publications32

  1. ncbi request reprint Effect of lindane on testicular antioxidant system and steroidogenic enzymes in adult rats
    R Sujatha
    School of Life Sciences, Pondicherry University, India
    Asian J Androl 3:135-8. 2001
    ..The levels of DNA, RNA and protein were also decreased in lindane-treated rats. CONCLUSION: Lindane induces oxidative stress and decreases antioxidant enzymes in adult male rats...
  2. ncbi request reprint Effect of lindane on antioxidant enzymes in epididymis and epididymal sperm of adult rats
    K C Chitra
    School of Life Sciences, Pondicherry University, India
    Asian J Androl 3:205-8. 2001
    ..CONCLUSION: Lindane decreases the levels of antioxidant enzymes in the epididymis and epididymal sperm of adult rats thereby inducing oxidative stress...
  3. ncbi request reprint Effect of methoxychlor on antioxidant system of goat epididymal sperm in vitro
    B Gangadharan
    School of Life Sciences, Pondicherry University, India
    Asian J Androl 3:285-8. 2001
    ..Co-incubation of sperm with methoxychlor and vitamin C, a natural antioxidant, reversed the effect of methoxychlor...
  4. ncbi request reprint The effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin on the antioxidant system in mitochondrial and microsomal fractions of rat testis
    C Latchoumycandane
    School of Life Sciences, Pondicherry University, 605 014, Pondicherry, India
    Toxicology 171:127-35. 2002
    ..In conclusion the adverse effect of TCDD on male reproduction could be due to induction of oxidative stress...
  5. ncbi request reprint The effect of methoxychlor on the epididymal antioxidant system of adult rats
    C Latchoumycandane
    School of Life Sciences, Pondicherry University, 605 014, India
    Reprod Toxicol 16:161-72. 2002
    ..In conclusion the adverse effect of methoxychlor on the male reproduction could be due to induction of oxidative stress...
  6. ncbi request reprint Bisphenol A induces reactive oxygen species generation in the liver of male rats
    V Bindhumol
    School of Life Sciences, Pondicherry University, Pondicherry 605 014, India
    Toxicology 188:117-24. 2003
    ..The results indicated that bisphenol A induces oxidative stress in the liver of rats by decreasing the antioxidant enzymes. Co-administration of vitamin C reversed the effects of bisphenol A-induced oxidative stress in the liver of rats...
  7. ncbi request reprint Induction of oxidative stress by bisphenol A in the epididymal sperm of rats
    K C Chitra
    School of Life Sciences, Pondicherry University, Pondicherry 605 014, India
    Toxicology 185:119-27. 2003
    ..In conclusion, the adverse effect of bisphenol A on male reproduction may be due to induction of oxidative stress in sperm...
  8. ncbi request reprint Effect of nonylphenol on the antioxidant system in epididymal sperm of rats
    K C Chitra
    School of Life Sciences, Pondicherry University, Pondicherry 605 014, India
    Arch Toxicol 76:545-51. 2002
    ..The results suggest that graded doses of nonylphenol elicit depletion of antioxidant defence system in sperm, indicating nonylphenol-induced oxidative stress in the epididymal sperm of rats...
  9. doi request reprint Effect of restraint stress on 2,3,7,8 tetrachloro dibenzo-p-dioxin induced testicular and epididymal toxicity in rats
    S Dhanabalan
    Department of Biochemistry and Molecular Biology, School of Life Sciences, Pondicherry University, Pondicherry, India
    Hum Exp Toxicol 30:567-78. 2011
    ..Thus, restraint stress potentiates the adverse effects of TCDD on male reproductive organs...
  10. ncbi request reprint Effect of methoxychlor on the antioxidant system in mitochondrial and microsome-rich fractions of rat testis
    C Latchoumycandane
    School of Life Sciences, Pondicherry University, Pondicherry 605 014, India
    Toxicology 176:67-75. 2002
    ..In conclusion, the adverse effect of methoxychlor on male reproduction could be due to the induction of oxidative stress in testis...
  11. ncbi request reprint Effect of bisphenol A and co-administration of bisphenol A and vitamin C on epididymis of adult rats: a histological and biochemical study
    K C Chitra
    School of Life Sciences, Pondicherry University, Pondicherry 605 014, India
    Asian J Androl 5:203-8. 2003
    ..To study the effect of bisphenol A on the epididymis and epididymal sperm of rats and the possible amelioration action of co-administration with vitamin C...
  12. doi request reprint Piperine activates testicular apoptosis in adult rats
    Shereen Cynthia D'Cruz
    Department of Biochemistry and Molecular Biology, School of Life Sciences, Pondicherry University, Pondicherry 605 014, India
    J Biochem Mol Toxicol 22:382-8. 2008
    ..These observations indicate that piperine induces oxidative stress and thereby triggers apoptosis in the testis, contributing to hampered reproductive functions...
  13. ncbi request reprint Vitamin E prevents nonylphenol-induced oxidative stress in testis of rats
    K C Chitra
    School of Life Sciences, Pondicherry University, Pondicherry 605 014, India
    Indian J Exp Biol 42:220-3. 2004
    ....
  14. ncbi request reprint Long-term exposure to nonylphenol affects insulin signaling in the liver of adult male rats
    R Jubendradass
    Department of Biochemistry and Molecular Biology, School of Life Sciences, Pondicherry University, Pondicherry, India
    Hum Exp Toxicol 31:868-76. 2012
    ..These results suggest that NP downregulates insulin signaling in liver, which could be due to ROS production and oxidative damage...
  15. ncbi request reprint Effect of piperine on the epididymis of adult male rats
    S C D'cruz
    School of Life Sciences, Pondicherry University, Pondicherry 605014, India
    Asian J Androl 7:363-8. 2005
    ..To study the effect of piperine on the epididymal antioxidant system of adult male rats...
  16. ncbi request reprint Effects of vitamin E on reactive oxygen species-mediated 2,3,7,8-tetrachlorodi-benzo-p-dioxin toxicity in rat testis
    C Latchoumycandane
    School of Life Sciences, Pondicherry University, Pondicherry 605 014, India
    J Appl Toxicol 22:345-51. 2002
    ..The results suggested that administration of TCDD induces oxidative stress in testis, and vitamin E could impart a protective effect against TCDD-induced oxidative stress...
  17. doi request reprint Transient inhibitory effect of methoxychlor on testicular steroidogenesis in rat: an in vivo study
    S Vaithinathan
    Department of Biochemistry and Molecular Biology, School of Life Sciences, Pondicherry University, Pondicherry 605014, India
    Arch Toxicol 82:833-9. 2008
    ..The present study demonstrates transient effect of methoxychlor at LOAEL on testicular steroidogenesis and the possible role of hydrogen peroxide in mediating these effects...
  18. doi request reprint Effects of corticosterone and 2,3,7,8-tetrachloro- dibenzo-p-dioxin on epididymal antioxidant system in adult rats
    S Dhanabalan
    Department of Biochemistry and Molecular Biology, School of Life Sciences, Pondicherry University, Pondicherry 605 014, India
    J Biochem Mol Toxicol 24:242-9. 2010
    ..Stress, characterized by increased glucocorticoid levels and activity, may enhance TCDD-induced epididymal toxicity...
  19. ncbi request reprint Induction of oxidative stress in the rat testis after short-term exposure to the organochlorine pesticide methoxychlor
    C Latchoumycandane
    School of Life Sciences, Pondicherry University, India
    Arch Toxicol 76:692-8. 2002
    ..In conclusion, the adverse effect of methoxychlor on the male reproduction could be due to induction of oxidative stress in testis...
  20. ncbi request reprint 2,3,7,8-tetrachlorodibenzo- p-dioxin (TCDD) induces oxidative stress in the epididymis and epididymal sperm of adult rats
    C Latchoumycandane
    School of Life Sciences, Pondicherry University, 605 014, Pondicherry, India
    Arch Toxicol 77:280-4. 2003
    ..Thus, the adverse effects of TCDD on the epididymal sperm were due to direct effect of TCDD on epididymis...
  21. doi request reprint Methoxychlor-induced alteration in the levels of HSP70 and clusterin is accompanied with oxidative stress in adult rat testis
    S Vaithinathan
    Department of Biochemistry and Molecular Biology, School of Life Sciences, Pondicherry University, Pondicherry, India
    J Biochem Mol Toxicol 23:29-35. 2009
    ..The present data demonstrate methoxychlor-elicited increase in the levels of inducible HSP72 and sCLU, which could be a part of protective mechanism mounted to reduce cellular oxidative damage...
  22. doi request reprint Short-term exposure to nonylphenol induces pancreatic oxidative stress and alters liver glucose metabolism in adult female rats
    R Jubendradass
    Department of Biochemistry and Molecular Biology, School of Life Sciences, Pondicherry University, Pondicherry 605 014, India
    J Biochem Mol Toxicol 25:77-83. 2011
    ..Western blot analysis revealed a significant decrease in the levels of GLUT-2. These results show that nonylphenol causes oxidative stress in pancreas and impairs liver glucose homeostasis...
  23. doi request reprint Low dose of 2,3,7,8 tetrachlorodibenzo-p-dioxin induces testicular oxidative stress in adult rats under the influence of corticosterone
    S Dhanabalan
    Department of Biochemistry and Molecular Biology, School of Life Sciences, Pondicherry University, Pondicherry, India
    Exp Toxicol Pathol 61:415-23. 2009
    ..It is concluded that stress may enhance the effects of TCDD on the testis...
  24. doi request reprint Methoxychlor induces apoptosis via mitochondria- and FasL-mediated pathways in adult rat testis
    S Vaithinathan
    Department of Biochemistry and Molecular Biology, Pondicherry University, India
    Chem Biol Interact 185:110-8. 2010
    ..The study demonstrates induction of testicular apoptosis in adult rats following exposure to a single dose of methoxychlor...
  25. ncbi request reprint Lindane alters the levels of HSP70 and clusterin in adult rat testis
    B Saradha
    Department of Biochemistry and Molecular Biology, School of Life Sciences, Pondicherry University, Pondicherry 605 014, India
    Toxicology 243:116-23. 2008
    ..These findings indicate a transitory state of stress induced by lindane in rat testis accompanied by an alteration in the levels of stress proteins, which could be a part of protective mechanism mounted to reduce cellular damage...
  26. doi request reprint Lindane induces testicular apoptosis in adult Wistar rats through the involvement of Fas-FasL and mitochondria-dependent pathways
    B Saradha
    Department of Biochemistry and Molecular Biology, School of Life Sciences, Pondicherry University, Pondicherry 605 014, India
    Toxicology 255:131-9. 2009
    ..Early activation of NF-kappaB in contrast to late increase in Fas expression suggests a pro-apoptotic role of NF-kappaB in testicular response to lindane...
  27. ncbi request reprint Antioxidative effect of fullerenol on goat epididymal spermatozoa
    M Arul Murugan
    School of Life Sciences, Pondicherry University, Pondicherry 605 014, India
    Asian J Androl 4:149-52. 2002
    ..To evaluate the effect of fullerenol on the antioxidant system of goat epididymal sperm...
  28. doi request reprint Single exposure to low dose of lindane causes transient decrease in testicular steroidogenesis in adult male Wistar rats
    B Saradha
    Department of Biochemistry and Molecular Biology, School of Life Sciences, Pondicherry University, Pondicherry 605 014, India
    Toxicology 244:190-7. 2008
    ..These findings demonstrate transient inhibitory effects of lindane on testicular steroidogenesis and the possible role of H2O2 in mediating these effects...
  29. doi request reprint Nonylphenol induces apoptosis via mitochondria- and Fas-L-mediated pathways in the liver of adult male rat
    R Jubendradass
    Department of Biochemistry and Molecular Biology, School of Life Sciences, Pondicherry University, Pondicherry 605 014, India
    Regul Toxicol Pharmacol 62:405-11. 2012
    ..It is concluded that NP induces apoptosis in liver involving both mitochondria-dependent and Fas-Fas-l pathways and thereby, leading to hepatic damage in rats...
  30. doi request reprint Adjudin-mediated germ cell depletion alters the anti-oxidant status of adult rat testis
    Oli Sarkar
    Department of Biochemistry and Molecular Biology, School of Life Sciences, Pondicherry University, Pondicherry, India
    Mol Reprod Dev 76:31-7. 2009
    ..However, transient elevation in reactive oxygen species levels did not affect androgen transport...
  31. doi request reprint Kolaviron prevents carbendazim-induced steroidogenic dysfunction and apoptosis in testes of rats
    I A Adedara
    Department of Biochemistry and Molecular Biology, School of Life Sciences, Pondicherry University, Pondicherry 605014, India
    Environ Toxicol Pharmacol 35:444-53. 2013
    ..Kolaviron may prove useful in combating carbendazim-induced reproductive toxicity...
  32. ncbi request reprint Protein profiles in various epididymal segments of normal and castrated rats
    P P Mathur
    School of Life Sciences, Pondicherry University, Pondicherry 605 014, India
    Asian J Androl 2:57-64. 2000
    ..Epididymal proteins are known to play an important role in the maturation of spermatozoa. We ought to determine if there are regional differences in androgen-dependent epididymal proteins...