Mhairi Maskew

Summary

Publications

  1. pmc Kaposi sarcoma-associated herpes virus and response to antiretroviral therapy: a prospective study of HIV-infected adults
    Mhairi Maskew
    Health Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South
    J Acquir Immune Defic Syndr 63:442-8. 2013
  2. ncbi Impact of choice of NRTI in first-line antiretroviral therapy: a cohort analysis of stavudine vs. tenofovir
    Alana T Brennan
    Center for Global Health and Development, Boston University, Boston, MA, USA Health Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
    Trop Med Int Health 19:490-8. 2014
  3. pmc Initiating antiretroviral therapy when presenting with higher CD4 cell counts results in reduced loss to follow-up in a resource-limited setting
    Kate Clouse
    Department of Internal Medicine, University of the Witwatersrand, Johannesburg, South Africa
    AIDS 27:645-50. 2013
  4. pmc Loss to follow-up before and after delivery among women testing HIV positive during pregnancy in Johannesburg, South Africa
    Kate Clouse
    Health Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
    Trop Med Int Health 18:451-60. 2013
  5. pmc Gender differences in mortality and CD4 count response among virally suppressed HIV-positive patients
    Mhairi Maskew
    Health Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
    J Womens Health (Larchmt) 22:113-20. 2013
  6. pmc Treatment response and mortality among patients starting antiretroviral therapy with and without Kaposi sarcoma: a cohort study
    Mhairi Maskew
    Health Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
    PLoS ONE 8:e64392. 2013
  7. pmc The interplay between CD4 cell count, viral load suppression and duration of antiretroviral therapy on mortality in a resource-limited setting
    Alana T Brennan
    Center for Global Health and Development, Boston University, Boston, MA, USA Health Economics and Epidemiology Research Office, University of the Witwatersrand, Johannesburg, South Africa
    Trop Med Int Health 18:619-31. 2013
  8. pmc Increases in regimen durability associated with the introduction of tenofovir at a large public-sector clinic in Johannesburg, South Africa
    Alana T Brennan
    Center for Global Health and Development, Boston University, Boston, MA, USA Health Economics and Epidemiology Research Office, Faculty of Health Sciences, Department of Internal Medicine, School of Clinical Medicine, University of the Witwatersrand, Johannesburg, South Africa
    J Int AIDS Soc 16:18794. 2013
  9. pmc Treatment outcomes of HIV-infected adolescents attending public-sector HIV clinics across Gauteng and Mpumalanga, South Africa
    Denise Evans
    Health Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, University of the Witwatersrand, Johannesburg, South Africa
    AIDS Res Hum Retroviruses 29:892-900. 2013
  10. pmc Poorer ART outcomes with increasing age at a large public sector HIV clinic in Johannesburg, South Africa
    Mhairi Maskew
    1Department of Medicine, Clinical HIV Research Unit, University of the Witwatersrand, Johannesburg, South Africa
    J Int Assoc Physicians AIDS Care (Chic) 11:57-65. 2012

Detail Information

Publications23

  1. pmc Kaposi sarcoma-associated herpes virus and response to antiretroviral therapy: a prospective study of HIV-infected adults
    Mhairi Maskew
    Health Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South
    J Acquir Immune Defic Syndr 63:442-8. 2013
    ..The possible impact of coinfection with the Kaposi sarcoma-associated herpes virus (KSHV) on the response to antiretroviral therapy (ART) is unknown. Prospective studies are rare, particularly in Africa...
  2. ncbi Impact of choice of NRTI in first-line antiretroviral therapy: a cohort analysis of stavudine vs. tenofovir
    Alana T Brennan
    Center for Global Health and Development, Boston University, Boston, MA, USA Health Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
    Trop Med Int Health 19:490-8. 2014
    ..We examined treatment outcomes over 24 months amongst patients initiated on tenofovir-based vs. stavudine-based first-line regimens...
  3. pmc Initiating antiretroviral therapy when presenting with higher CD4 cell counts results in reduced loss to follow-up in a resource-limited setting
    Kate Clouse
    Department of Internal Medicine, University of the Witwatersrand, Johannesburg, South Africa
    AIDS 27:645-50. 2013
    ..Mortality and morbidity are known to be reduced when initiating at higher CD4 levels; we explored the impact on patient loss to follow-up...
  4. pmc Loss to follow-up before and after delivery among women testing HIV positive during pregnancy in Johannesburg, South Africa
    Kate Clouse
    Health Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
    Trop Med Int Health 18:451-60. 2013
    ..HIV-positive pregnant women are at heightened risk of becoming lost to follow-up (LTFU) from HIV care. We examined LTFU before and after delivery among pregnant women newly diagnosed with HIV...
  5. pmc Gender differences in mortality and CD4 count response among virally suppressed HIV-positive patients
    Mhairi Maskew
    Health Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
    J Womens Health (Larchmt) 22:113-20. 2013
    ..We investigated the gender differences in treatment response among HIV-positive patients virally suppressed within 6 months of treatment initiation...
  6. pmc Treatment response and mortality among patients starting antiretroviral therapy with and without Kaposi sarcoma: a cohort study
    Mhairi Maskew
    Health Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
    PLoS ONE 8:e64392. 2013
    ..However, the effect of KS on response to ART is not well-described in Southern Africa. We assessed the effect of KS on survival and immunologic and virologic treatment responses at 6- and 12-months after initiation of ART...
  7. pmc The interplay between CD4 cell count, viral load suppression and duration of antiretroviral therapy on mortality in a resource-limited setting
    Alana T Brennan
    Center for Global Health and Development, Boston University, Boston, MA, USA Health Economics and Epidemiology Research Office, University of the Witwatersrand, Johannesburg, South Africa
    Trop Med Int Health 18:619-31. 2013
    ..To examine the interaction between CD4 cell count, viral load suppression and duration of antiretroviral therapy (ART) on mortality...
  8. pmc Increases in regimen durability associated with the introduction of tenofovir at a large public-sector clinic in Johannesburg, South Africa
    Alana T Brennan
    Center for Global Health and Development, Boston University, Boston, MA, USA Health Economics and Epidemiology Research Office, Faculty of Health Sciences, Department of Internal Medicine, School of Clinical Medicine, University of the Witwatersrand, Johannesburg, South Africa
    J Int AIDS Soc 16:18794. 2013
    ..Conclusions: The decline in single-drug substitutions is associated with the introduction of tenofovir. Tenofovir use could improve regimen durability and treatment outcomes in resource-limited settings. ..
  9. pmc Treatment outcomes of HIV-infected adolescents attending public-sector HIV clinics across Gauteng and Mpumalanga, South Africa
    Denise Evans
    Health Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, University of the Witwatersrand, Johannesburg, South Africa
    AIDS Res Hum Retroviruses 29:892-900. 2013
    ..Interventions are needed to help improve outcomes and retention in care in this unique population...
  10. pmc Poorer ART outcomes with increasing age at a large public sector HIV clinic in Johannesburg, South Africa
    Mhairi Maskew
    1Department of Medicine, Clinical HIV Research Unit, University of the Witwatersrand, Johannesburg, South Africa
    J Int Assoc Physicians AIDS Care (Chic) 11:57-65. 2012
    ..As the current HIV-positive population ages, the absolute number of patients >50 years on treatment is increasing...
  11. pmc The impact of choice of NNRTI on short-term treatment outcomes among HIV-infected patients prescribed tenofovir and lamivudine in Johannesburg, South Africa
    Kate Shearer
    Health Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
    PLoS ONE 8:e71719. 2013
    ..We sought to compare outcomes among those taking nevirapine vs. efavirenz with tenofovir and lamivudine...
  12. pmc Increased risk of mortality and loss to follow-up among HIV-positive patients with oropharyngeal candidiasis and malnutrition before antiretroviral therapy initiation: a retrospective analysis from a large urban cohort in Johannesburg, South Africa
    Denise Evans
    Clinical HIV Research Unit, Department of Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
    Oral Surg Oral Med Oral Pathol Oral Radiol 113:362-72. 2012
    ..We investigated the effect of oropharyngeal candidiasis (OC) and body mass index (BMI) before antiretroviral therapy (ART) initiation on treatment outcomes of human immunodeficiency virus (HIV)-positive patients...
  13. pmc Patient retention from HIV diagnosis through one year on antiretroviral therapy at a primary health care clinic in Johannesburg, South Africa
    Kate Clouse
    Health Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
    J Acquir Immune Defic Syndr 62:e39-46. 2013
    ..To compare patient retention at 3 stages of pre-antiretroviral (ART) care and 2 stages of post-ART care to identify when greatest attrition occurs...
  14. doi Prevalence of peripheral neuropathy in antiretroviral therapy naïve HIV-positive patients and the impact on treatment outcomes--a retrospective study from a large urban cohort in Johannesburg, South Africa
    Denise Evans
    Health Economics and Epidemiology Research Office, Department of Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, 2041, South Africa
    J Neurovirol 18:162-71. 2012
    ..Completion of TB treatment may reduce the risk of persistent PN in patients with TB-related PN. Use of HIV drugs, even neurotoxic ones, may overall limit neuropathy...
  15. pmc Effectiveness and safety of 30 mg versus 40 mg stavudine regimens: a cohort study among HIV-infected adults initiating HAART in South Africa
    Mhairi Maskew
    Clinical HIV Research Unit, Department of Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
    J Int AIDS Soc 15:13. 2012
    ....
  16. pmc Outcomes of stable HIV-positive patients down-referred from a doctor-managed antiretroviral therapy clinic to a nurse-managed primary health clinic for monitoring and treatment
    Alana T Brennan
    Health Economics and Epidemiology Research Office, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
    AIDS 25:2027-36. 2011
    ....
  17. pmc Poor CD4 recovery and risk of subsequent progression to AIDS or death despite viral suppression in a South African cohort
    Simbarashe Takuva
    Clinical HIV Research Unit, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
    J Int AIDS Soc 17:18651. 2014
    ..The prognostic role of CD4 response in the first six months of treatment in patients achieving early viral suppression during HIV treatment is unclear...
  18. doi Prevalence of hepatitis B virus (HBV) co-infection in HBV serologically-negative South African HIV patients and retrospective evaluation of the clinical course of mono- and co-infection
    Cindy Firnhaber
    Clinical HIV Research Unit, Department of Internal Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
    Int J Infect Dis 16:e268-72. 2012
    ..This study presents the prevalence of HBV DNA in HIV-positive patients negative for all HBV serological markers and a retrospective evaluation of the clinical course of mono- and co-infection...
  19. pmc Tenofovir use and pregnancy among women initiating HAART
    Mhairi Maskew
    Health Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
    AIDS 26:2393-7. 2012
    ..Here, our objective was to determine among HIV-positive women whether use of tenofovir at HAART initiation or thereafter is associated with subsequent changes in incidence of pregnancy...
  20. pmc The feasibility of using screening criteria to reduce clinic visits for stable patients on antiretroviral therapy in South Africa
    William B MacLeod
    Health Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
    J Acquir Immune Defic Syndr 62:e82-6. 2013
    ..We used routinely collected data to model whether a simple screening tool could identify stable patients who would not need to see a doctor during a scheduled medical visit...
  21. pmc Incidence and predictors of herpes zoster among antiretroviral therapy-naïve patients initiating HIV treatment in Johannesburg, South Africa
    Kate Shearer
    Health Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa Electronic address
    Int J Infect Dis 23:56-62. 2014
    ..To describe the characteristics of HIV-infected patients experiencing herpes zoster after antiretroviral therapy (ART) initiation and to describe the incidence and predictors of a herpes zoster diagnosis...
  22. pmc A longitudinal study of stavudine-associated toxicities in a large cohort of South African HIV infected subjects
    Colin N Menezes
    Infectious Diseases Unit, Department of Medicine, Helen Joseph Hospital, University of the Witwatersrand, Johannesburg, South Africa
    BMC Infect Dis 11:244. 2011
    ..This has brought new challenges which include the effects of stavudine-related toxicities...
  23. pmc Occult hepatitis B virus infection in patients with isolated core antibody and HIV co-infection in an urban clinic in Johannesburg, South Africa
    Cynthia Firnhaber
    Clinical HIV Research Unit, Department of Medicine, University of the Witwatersrand, Johannesburg, South Africa
    Int J Infect Dis 13:488-92. 2009
    ..However, sensitive molecular techniques for detecting HBV DNA in serum can detect occult HBV infection. We report the first observational prospective study of occult HBV infection in HIV-positive people in South Africa...