Keri Martinowich

Summary

Publications

  1. pmc Acetylcholinesterase inhibition ameliorates deficits in motivational drive
    Keri Martinowich
    Mood and Anxiety Disorders Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892 3711, USA
    Behav Brain Funct 8:15. 2012
  2. pmc Roles of p75(NTR), long-term depression, and cholinergic transmission in anxiety and acute stress coping
    Keri Martinowich
    Mood and Anxiety Disorders Program, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA
    Biol Psychiatry 71:75-83. 2012
  3. pmc Role of activity-dependent BDNF expression in hippocampal-prefrontal cortical regulation of behavioral perseverance
    Kazuko Sakata
    Section on Neural Development and Plasticity, National Institute of Child Health and Human Development, Genes, Cognition and Psychosis Program, Laboratory of Molecular Pathophysiology, National Institute of Mental Health, and National Cancer Institute, National Institutes of Health, Bethesda, MD 20892
    Proc Natl Acad Sci U S A 110:15103-8. 2013
  4. pmc Direct current stimulation promotes BDNF-dependent synaptic plasticity: potential implications for motor learning
    Brita Fritsch
    Epilepsy Research Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA
    Neuron 66:198-204. 2010
  5. pmc Atrophy of pyramidal neurons and increased stress-induced glutamate levels in CA3 following chronic suppression of adult neurogenesis
    Robert J Schloesser
    Mood and Anxiety Disorders Program, National Institute of Mental Health NIMH, National Institutes of Health NIH, Bethesda, MD, 20892, USA
    Brain Struct Funct 219:1139-48. 2014
  6. pmc TrkB as a potential synaptic and behavioral tag
    Yuan Lu
    Gene, Cognition and Psychosis Program, NIMH, National Institutes of Health, Bethesda, Maryland 20892 3714, USA
    J Neurosci 31:11762-71. 2011
  7. pmc Activity-dependent brain-derived neurotrophic factor expression regulates cortistatin-interneurons and sleep behavior
    Keri Martinowich
    Genes, Cognition and Psychosis Program GCAP, National Institute of Mental Health NIMH, Bethesda, MD 20892, USA
    Mol Brain 4:11. 2011
  8. pmc Glucocorticoids orchestrate divergent effects on mood through adult neurogenesis
    Michael L Lehmann
    Section on Functional Neuroanatomy, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892 3724, USA
    J Neurosci 33:2961-72. 2013
  9. pmc Suppression of adult neurogenesis leads to an increased hypothalamo-pituitary-adrenal axis response
    Robert J Schloesser
    Laboratory of Molecular Pathophysiology, Mood and Anxiety Disorders Program, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892 3711, USA
    Neuroreport 20:553-7. 2009
  10. pmc Critical role of promoter IV-driven BDNF transcription in GABAergic transmission and synaptic plasticity in the prefrontal cortex
    Kazuko Sakata
    Section on Neural Development and Plasticity, National Institute of Child Health and Human Development, National Institutes of Health, 35 Lincoln Drive, Bethesda, MD 20892 3714, USA
    Proc Natl Acad Sci U S A 106:5942-7. 2009

Collaborators

Detail Information

Publications10

  1. pmc Acetylcholinesterase inhibition ameliorates deficits in motivational drive
    Keri Martinowich
    Mood and Anxiety Disorders Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892 3711, USA
    Behav Brain Funct 8:15. 2012
    ..This study evaluated a chronic restraint stress (CRS) protocol in modeling apathetic behavior, and determined whether administration of an anticholinesterase had utility in attenuating CRS-induced phenotypes...
  2. pmc Roles of p75(NTR), long-term depression, and cholinergic transmission in anxiety and acute stress coping
    Keri Martinowich
    Mood and Anxiety Disorders Program, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA
    Biol Psychiatry 71:75-83. 2012
    ..This study investigated whether and how p75(NTR), via regulation of the cholinergic system and hippocampal synaptic plasticity, influences stress-related behaviors...
  3. pmc Role of activity-dependent BDNF expression in hippocampal-prefrontal cortical regulation of behavioral perseverance
    Kazuko Sakata
    Section on Neural Development and Plasticity, National Institute of Child Health and Human Development, Genes, Cognition and Psychosis Program, Laboratory of Molecular Pathophysiology, National Institute of Mental Health, and National Cancer Institute, National Institutes of Health, Bethesda, MD 20892
    Proc Natl Acad Sci U S A 110:15103-8. 2013
    ..These results suggest distinct roles for different forms of L-LTP and provide a link between activity-dependent BDNF expression and behavioral perseverance, a hallmark of several psychiatric disorders. ..
  4. pmc Direct current stimulation promotes BDNF-dependent synaptic plasticity: potential implications for motor learning
    Brita Fritsch
    Epilepsy Research Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA
    Neuron 66:198-204. 2010
    ..We propose that tDCS may improve motor skill learning through augmentation of synaptic plasticity that requires BDNF secretion and TrkB activation within M1...
  5. pmc Atrophy of pyramidal neurons and increased stress-induced glutamate levels in CA3 following chronic suppression of adult neurogenesis
    Robert J Schloesser
    Mood and Anxiety Disorders Program, National Institute of Mental Health NIMH, National Institutes of Health NIH, Bethesda, MD, 20892, USA
    Brain Struct Funct 219:1139-48. 2014
    ....
  6. pmc TrkB as a potential synaptic and behavioral tag
    Yuan Lu
    Gene, Cognition and Psychosis Program, NIMH, National Institutes of Health, Bethesda, Maryland 20892 3714, USA
    J Neurosci 31:11762-71. 2011
    ..Inhibition of TrkB during STM training blocked such consolidation. These results suggest TrkB as a potential tag for synapse-specific expression of L-LTP and LTM...
  7. pmc Activity-dependent brain-derived neurotrophic factor expression regulates cortistatin-interneurons and sleep behavior
    Keri Martinowich
    Genes, Cognition and Psychosis Program GCAP, National Institute of Mental Health NIMH, Bethesda, MD 20892, USA
    Mol Brain 4:11. 2011
    ..Cortistatin, a neuropeptide expressed primarily in a subset of cortical GABAergic interneurons, is another molecule implicated in sleep homeostasis...
  8. pmc Glucocorticoids orchestrate divergent effects on mood through adult neurogenesis
    Michael L Lehmann
    Section on Functional Neuroanatomy, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892 3724, USA
    J Neurosci 33:2961-72. 2013
    ..These data provide new evidence for direct involvement of neurogenesis in the etiology of depression, suggesting that treatments promoting neurogenesis can enhance stress resilience...
  9. pmc Suppression of adult neurogenesis leads to an increased hypothalamo-pituitary-adrenal axis response
    Robert J Schloesser
    Laboratory of Molecular Pathophysiology, Mood and Anxiety Disorders Program, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892 3711, USA
    Neuroreport 20:553-7. 2009
    ..This study suggests that suppressed neurogenesis regulates the hypothalamo-pituitary-adrenal axis response...
  10. pmc Critical role of promoter IV-driven BDNF transcription in GABAergic transmission and synaptic plasticity in the prefrontal cortex
    Kazuko Sakata
    Section on Neural Development and Plasticity, National Institute of Child Health and Human Development, National Institutes of Health, 35 Lincoln Drive, Bethesda, MD 20892 3714, USA
    Proc Natl Acad Sci U S A 106:5942-7. 2009
    ..These results demonstrate the importance of promoter IV-dependent Bdnf transcription in GABAergic function and reveal an unexpected regulation of STDP in the PFC by BDNF...