Ignacio Martin-Loeches

Summary

Publications

  1. pmc Critical COPD respiratory illness is linked to increased transcriptomic activity of neutrophil proteases genes
    Raquel Almansa
    Investigación Biomédica del Clínico ibC, Hospital Clinico Universitario de Valladolid, Avda Ramón y Cajal 3, 47005 Valladolid, Spain
    BMC Res Notes 5:401. 2012
  2. doi request reprint Macrolide-based regimens in absence of bacterial co-infection in critically ill H1N1 patients with primary viral pneumonia
    I Martin-Loeches
    Critical Care Center, ParcTaulí Hospital Sabadell, CibeRes, ParcTauli s n, 08208, Sabadell, Spain
    Intensive Care Med 39:693-702. 2013
  3. doi request reprint Effectiveness of an inspiratory pressure-limited approach to mechanical ventilation in septic patients
    Ignacio Martin-Loeches
    Critical Care Centre, Corporación Sanitaria Universitaria Parc Tauli, Sabadell University Hospital, Universidad Autonoma de Barcelona, CIBER Enfermedades Respiratorias, Sabadell, Spain
    Eur Respir J 41:157-64. 2013
  4. doi request reprint Intubated patients developing tracheobronchitis or pneumonia have distinctive complement system gene expression signatures in the pre-infection period: a pilot study
    I Martin-Loeches
    Critical Care Centre, Corporació Sanitaria Parc Taulí Hospital de Sabadell CIBERES, Sabadell, Spain
    Med Intensiva 36:257-63. 2012
  5. pmc Pandemic and post-pandemic influenza A (H1N1) infection in critically ill patients
    Ignacio Martin-Loeches
    Critical Care Center, Parc Taulí Hospital Sabadell, CibeRes, Sabadell, Spain
    Crit Care 15:R286. 2011
  6. doi request reprint Severe pandemic (H1N1)v influenza A infection: report on the first deaths in Spain
    Ignacio Martin-Loeches
    Critical Care Department, Joan XXIII University Hospital, Spain
    Respirology 16:78-85. 2011
  7. doi request reprint Community-acquired respiratory coinfection in critically ill patients with pandemic 2009 influenza A(H1N1) virus
    Ignacio Martin-Loeches
    Critical Care Department, Joan XXIII University Hospital, University Rovira i Virgili, CibeRes, Mallafre Guasch 4, 43007 Tarragona, Spain
    Chest 139:555-62. 2011
  8. pmc Acute kidney injury in critical ill patients affected by influenza A (H1N1) virus infection
    Ignacio Martin-Loeches
    Critical Care Department, Joan XXIII University Hospital CIBER Enfermedades Respiratorias, URV, and IISPV, Mallafre i Guasch, ES 43007 Tarragona, Spain
    Crit Care 15:R66. 2011
  9. pmc Host adaptive immunity deficiency in severe pandemic influenza
    Jesus F Bermejo-Martin
    Infection and Immunity Unit, Hospital Clínico Universitario IECSCYL, Avda, Ramon y Cajal 3, 47005 Valladolid, Spain
    Crit Care 14:R167. 2010
  10. pmc Th1 and Th17 hypercytokinemia as early host response signature in severe pandemic influenza
    Jesus F Bermejo-Martin
    National Centre of Influenza, Hospital Clinico Universitario de Valladolid, Valladolid, Spain
    Crit Care 13:R201. 2009

Detail Information

Publications25

  1. pmc Critical COPD respiratory illness is linked to increased transcriptomic activity of neutrophil proteases genes
    Raquel Almansa
    Investigación Biomédica del Clínico ibC, Hospital Clinico Universitario de Valladolid, Avda Ramón y Cajal 3, 47005 Valladolid, Spain
    BMC Res Notes 5:401. 2012
    ....
  2. doi request reprint Macrolide-based regimens in absence of bacterial co-infection in critically ill H1N1 patients with primary viral pneumonia
    I Martin-Loeches
    Critical Care Center, ParcTaulí Hospital Sabadell, CibeRes, ParcTauli s n, 08208, Sabadell, Spain
    Intensive Care Med 39:693-702. 2013
    ..To determine whether macrolide-based treatment is associated with mortality in critically ill H1N1 patients with primary viral pneumonia...
  3. doi request reprint Effectiveness of an inspiratory pressure-limited approach to mechanical ventilation in septic patients
    Ignacio Martin-Loeches
    Critical Care Centre, Corporación Sanitaria Universitaria Parc Tauli, Sabadell University Hospital, Universidad Autonoma de Barcelona, CIBER Enfermedades Respiratorias, Sabadell, Spain
    Eur Respir J 41:157-64. 2013
    ..84, 95% CI 0.72-0.99; p=0.038). ALI in sepsis was associated with higher mortality, especially when an inspiratory pressure-limited mechanical ventilation approach was not implemented...
  4. doi request reprint Intubated patients developing tracheobronchitis or pneumonia have distinctive complement system gene expression signatures in the pre-infection period: a pilot study
    I Martin-Loeches
    Critical Care Centre, Corporació Sanitaria Parc Taulí Hospital de Sabadell CIBERES, Sabadell, Spain
    Med Intensiva 36:257-63. 2012
    ..It remains unknown why some intubated patients remain infection-free while others develop tracheobronchitis (VAT) or pneumonia (VAP)...
  5. pmc Pandemic and post-pandemic influenza A (H1N1) infection in critically ill patients
    Ignacio Martin-Loeches
    Critical Care Center, Parc Taulí Hospital Sabadell, CibeRes, Sabadell, Spain
    Crit Care 15:R286. 2011
    ..There is a vast amount of information published regarding the impact of 2009 pandemic Influenza A (pH1N1) virus infection. However, a comparison of risk factors and outcome during the 2010-2011 post-pandemic period has not been described...
  6. doi request reprint Severe pandemic (H1N1)v influenza A infection: report on the first deaths in Spain
    Ignacio Martin-Loeches
    Critical Care Department, Joan XXIII University Hospital, Spain
    Respirology 16:78-85. 2011
    ..The impact of pandemic influenza A (H1N1)v infection is still unknown but it is associated with a high case-fatality rate...
  7. doi request reprint Community-acquired respiratory coinfection in critically ill patients with pandemic 2009 influenza A(H1N1) virus
    Ignacio Martin-Loeches
    Critical Care Department, Joan XXIII University Hospital, University Rovira i Virgili, CibeRes, Mallafre Guasch 4, 43007 Tarragona, Spain
    Chest 139:555-62. 2011
    ..Little is known about the impact of community-acquired respiratory coinfection in patients with pandemic 2009 influenza A(H1N1) virus infection...
  8. pmc Acute kidney injury in critical ill patients affected by influenza A (H1N1) virus infection
    Ignacio Martin-Loeches
    Critical Care Department, Joan XXIII University Hospital CIBER Enfermedades Respiratorias, URV, and IISPV, Mallafre i Guasch, ES 43007 Tarragona, Spain
    Crit Care 15:R66. 2011
    ..Little information exists about the impact of acute kidney injury (AKI) in critically ill patients with the pandemic 2009 influenza A (H1N1) virus infection...
  9. pmc Host adaptive immunity deficiency in severe pandemic influenza
    Jesus F Bermejo-Martin
    Infection and Immunity Unit, Hospital Clínico Universitario IECSCYL, Avda, Ramon y Cajal 3, 47005 Valladolid, Spain
    Crit Care 14:R167. 2010
    ..Pandemic A/H1N1/2009 influenza causes severe lower respiratory complications in rare cases. The association between host immune responses and clinical outcome in severe cases is unknown...
  10. pmc Th1 and Th17 hypercytokinemia as early host response signature in severe pandemic influenza
    Jesus F Bermejo-Martin
    National Centre of Influenza, Hospital Clinico Universitario de Valladolid, Valladolid, Spain
    Crit Care 13:R201. 2009
    ..We utilize here systemic cytokine and antibody levels in evaluating differences in early immune response in both mild and severe patients infected with nvH1N1...
  11. pmc Direct association between pharyngeal viral secretion and host cytokine response in severe pandemic influenza
    Raquel Almansa
    Infection and Immunity Medical Investigation Unit IMI, Hospital Clínico Universitario IECSCYL, Avda Ramón, y Cajal 3, 47005 Valladolid, Spain
    BMC Infect Dis 11:232. 2011
    ..The objective of the present study was to evaluate the relationship between host cytokine responses and viral levels in pandemic influenza critically ill patients...
  12. doi request reprint Impact of obesity in patients infected with 2009 influenza A(H1N1)
    Emili Diaz
    Critical Care Department, Hospital Universitario Joan XXIII CIBER Enfermedades Respiratorias, URV, and IISPV, Carrer Dr, Mallafre Guasch 4, 43007 Tarragona, Spain
    Chest 139:382-6. 2011
    ..However, its role remains unclear. We evaluate the outcome of patients who are obese and infected with A(H1N1) in the ICU, determining whether obesity is a risk factor for mortality...
  13. doi request reprint Efficacy of single-dose antibiotic against early-onset pneumonia in comatose patients who are ventilated
    Jordi Valles
    Critical Care Center, Hospital Sabadell, Consorci Hospitalari Universitari Parc Taulí, CIBER Enfermedades Respiratorias, Sabadell, Spain
    Chest 143:1219-25. 2013
    ..Comatose patients were studied to evaluate the efficacy of a single-dose of antibiotic prophylaxis at intubation against EO-VAP...
  14. pmc Bacteremia is an independent risk factor for mortality in nosocomial pneumonia: a prospective and observational multicenter study
    Monica Magret
    Critical Care Department, Vall d Hebron University Hospital, CibeRes, VHIR, Universitat Autonoma de Barcelona, Vall d Hebron St, Barcelona 08035, Spain
    Crit Care 15:R62. 2011
    ..The purpose of the study is to compare risk factors, pathogens and outcomes between bacteremic nosocomial pneumonia (B-NP) and nonbacteremic nosocomial pneumonia (NB-NP) episodes...
  15. doi request reprint Mortality and regional oxygen saturation index in septic shock patients: a pilot study
    Alejandro Rodriguez
    Critical Care Department, Joan XXIII University Hospital, University Rovira i Virgili, IISPV, CIBER Enfermedades Respiratorias, Tarragona, Spain
    J Trauma 70:1145-52. 2011
    ....
  16. doi request reprint Evolution over a 15-year period of clinical characteristics and outcomes of critically ill patients with community-acquired bacteremia
    Jordi Valles
    Critical Care Center, Parc Taulí Hospital Sabadell, UAB, CIBER Enfermedades Respiratorias, Sabadell, Spain
    Crit Care Med 41:76-83. 2013
    ..We aimed to analyze the changes in the prevalence, characteristics, and outcome of critically ill patients with community-acquired bacteremia over the past 15 yrs...
  17. doi request reprint Corticosteroid therapy in patients with primary viral pneumonia due to pandemic (H1N1) 2009 influenza
    Emili Diaz
    Critical Care Department, Hospital Sant Joan Despí Moisès Broggi, Jacint Verdaguer, 90, 08970 Sant Joan Despí, Barcelona, CibeRes, IISPV, Spain
    J Infect 64:311-8. 2012
    ..The objective of this study was to assess the effect on survival of corticosteroid therapy in patients with pandemic (H1N1) 2009 influenza...
  18. doi request reprint Epidemiology, antibiotic therapy and clinical outcomes of healthcare-associated pneumonia in critically ill patients: a Spanish cohort study
    Jordi Valles
    Area de Patología Crítica, Critical Care Department, Hospital de Sabadell, Corporació Sanitària Universitària Parc Taulí, Parc Tauli s n, Sabadell, Spain
    Intensive Care Med 40:572-81. 2014
    ..Information about healthcare-associated pneumonia (HCAP) in critically ill patients is scarce...
  19. doi request reprint Potentially resistant microorganisms in intubated patients with hospital-acquired pneumonia: the interaction of ecology, shock and risk factors
    Ignacio Martin-Loeches
    Critical Care Centre, Coporació Sanitaria Parc Tauli, Sabadell, Spain
    Intensive Care Med 39:672-81. 2013
    ....
  20. doi request reprint Ventilator-associated pneumonia in trauma patients is associated with lower mortality: results from EU-VAP study
    M Magret
    Critical Care Department, Sant Joan University Hospital, Reus, Spain
    J Trauma 69:849-54. 2010
    ..Differences in trauma patients developing ventilator-associated pneumonia (VAP) are described regarding etiology and risk factors associated. We aim to describe the differences in outcomes in trauma and nontrauma patients with VAP...
  21. doi request reprint Use of early corticosteroid therapy on ICU admission in patients affected by severe pandemic (H1N1)v influenza A infection
    I Martin-Loeches
    Critical Care Department, Joan XXIII University Hospital, University Rovira i Virgili, IISPV, CIBER Enfermedades Respiratorias CIBERES, Tarragona, Spain
    Intensive Care Med 37:272-83. 2011
    ..Early use of corticosteroids in patients affected by pandemic (H1N1)v influenza A infection, although relatively common, remains controversial...
  22. doi request reprint [Nosocomial pneumonia]
    Emili Diaz
    Servicio de Medicina Intensiva, Hospital de Sabadell, Corporació Sanitària Universitària Parc Taulí, CIBER Enfermedades Respiratorias, Sabadell, Barcelona, Espana
    Enferm Infecc Microbiol Clin 31:692-8. 2013
    ..Additionally, clinical strategies aimed at the prevention of HAP and VAP should be employed in hospital settings caring for patients at risk for these infections. ..
  23. pmc Acute respiratory distress syndrome: prevention and early recognition
    Candelaria de Haro
    Critical Care Centre, Hospital de Sabadell, Corporació Sanitària i Universitària Parc Taulí, Universitat Autonoma de Barcelona, CIBER Enfermedades Respiratorias, Sabadell, Spain
    Ann Intensive Care 3:11. 2013
    ..Identifying patients at risk and implementing prevention strategies in this group are key factors in preventing ARDS. This review will discuss early identification of at-risk patients and the current prevention strategies...
  24. doi request reprint Variants at the promoter of the interleukin-6 gene are associated with severity and outcome of pneumococcal community-acquired pneumonia
    Ignacio Martin-Loeches
    Critical Care Centre, Corporació Sanitaria Parc Tauli University Hospital Sabadell, Sabadell, Spain
    Intensive Care Med 38:256-62. 2012
    ..We studied the genetic variability at IL6 in patients with community-acquired pneumonia (CAP) and pneumococcal CAP (P-CAP)...
  25. doi request reprint Mortality in ICU patients with bacterial community-acquired pneumonia: when antibiotics are not enough
    Alejandro Rodriguez
    Critical Care Department, Pere Virgili Health Institut and CIBER Enfermedades Respiratorias, Joan XXIII University Hospital, Tarragona, Spain
    Intensive Care Med 35:430-8. 2009
    ..It remains uncertain why immunocompetent patients with bacterial community-acquired pneumonia (CAP) die, in spite of adequate antibiotics...