Jeanne M Marrazzo

Summary

Publications

  1. pmc Interventions to prevent sexually transmitted infections, including HIV infection
    Jeanne M Marrazzo
    Department of Medicine, Division of Allergy and Infectious Diseases, University of Seattle, WA 98104, USA
    Clin Infect Dis 53:S64-78. 2011
  2. pmc Extravaginal reservoirs of vaginal bacteria as risk factors for incident bacterial vaginosis
    Jeanne M Marrazzo
    Department of Medicine, Division of Allergy and Infectious Diseases, University of Washington, WA, USA
    J Infect Dis 205:1580-8. 2012
  3. pmc Risks for acquisition of bacterial vaginosis among women who report sex with women: a cohort study
    Jeanne M Marrazzo
    Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, Washington, United States of America
    PLoS ONE 5:e11139. 2010
  4. pmc Interpreting the epidemiology and natural history of bacterial vaginosis: are we still confused?
    Jeanne M Marrazzo
    Department of Medicine, Division of Allergy and Infectious Diseases, University of Washington, Seattle, 98104, United States
    Anaerobe 17:186-90. 2011
  5. pmc A behavioural intervention to reduce persistence of bacterial vaginosis among women who report sex with women: results of a randomised trial
    Jeanne M Marrazzo
    Division of Allergy and Infectious Diseases, University of Washington, Seattle, Washington, USA
    Sex Transm Infect 87:399-405. 2011
  6. pmc Bacterial vaginosis: identifying research gaps proceedings of a workshop sponsored by DHHS/NIH/NIAID
    Jeanne M Marrazzo
    University of Washington, Seattle, WA, USA
    Sex Transm Dis 37:732-44. 2010
  7. pmc Relationship of specific vaginal bacteria and bacterial vaginosis treatment failure in women who have sex with women
    Jeanne M Marrazzo
    University of Washington and the Fred Hutchinson Cancer Research Center, Seattle, Washington, USA
    Ann Intern Med 149:20-8. 2008
  8. pmc More than meets the eye: associations of vaginal bacteria with gram stain morphotypes using molecular phylogenetic analysis
    Sujatha Srinivasan
    Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
    PLoS ONE 8:e78633. 2013
  9. pmc Temporal variability of human vaginal bacteria and relationship with bacterial vaginosis
    Sujatha Srinivasan
    Vaccine and Infectious Disease Institute, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
    PLoS ONE 5:e10197. 2010
  10. pmc Changes in vaginal bacterial concentrations with intravaginal metronidazole therapy for bacterial vaginosis as assessed by quantitative PCR
    David N Fredricks
    Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
    J Clin Microbiol 47:721-6. 2009

Detail Information

Publications42

  1. pmc Interventions to prevent sexually transmitted infections, including HIV infection
    Jeanne M Marrazzo
    Department of Medicine, Division of Allergy and Infectious Diseases, University of Seattle, WA 98104, USA
    Clin Infect Dis 53:S64-78. 2011
    ....
  2. pmc Extravaginal reservoirs of vaginal bacteria as risk factors for incident bacterial vaginosis
    Jeanne M Marrazzo
    Department of Medicine, Division of Allergy and Infectious Diseases, University of Washington, WA, USA
    J Infect Dis 205:1580-8. 2012
    ..to diverse anaerobes. Although antibiotics relieve symptoms and temporarily eradicate BV-associated bacteria (BVAB), BV usually recurs. We investigated the role of extravaginal BVAB reservoirs in recurrence...
  3. pmc Risks for acquisition of bacterial vaginosis among women who report sex with women: a cohort study
    Jeanne M Marrazzo
    Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, Washington, United States of America
    PLoS ONE 5:e11139. 2010
    ..Bacterial vaginosis (BV) is common in women who have sex with women. While cross-sectional data support a role for sexual transmission, risks for incident BV have not been prospectively studied in this group...
  4. pmc Interpreting the epidemiology and natural history of bacterial vaginosis: are we still confused?
    Jeanne M Marrazzo
    Department of Medicine, Division of Allergy and Infectious Diseases, University of Washington, Seattle, 98104, United States
    Anaerobe 17:186-90. 2011
    ..This review provides background on BV, and discusses the epidemiologic and microbiologic data to support a role for acquisition of BVAB and how this process might differ among subsets of women...
  5. pmc A behavioural intervention to reduce persistence of bacterial vaginosis among women who report sex with women: results of a randomised trial
    Jeanne M Marrazzo
    Division of Allergy and Infectious Diseases, University of Washington, Seattle, Washington, USA
    Sex Transm Infect 87:399-405. 2011
    ..Risks include sexual behaviours that transmit vaginal fluid. The authors measured efficacy of a behavioural intervention to reduce sexual transfer of vaginal fluid between female sex partners in reducing BV persistence...
  6. pmc Bacterial vaginosis: identifying research gaps proceedings of a workshop sponsored by DHHS/NIH/NIAID
    Jeanne M Marrazzo
    University of Washington, Seattle, WA, USA
    Sex Transm Dis 37:732-44. 2010
    ..In this report, we offer suggestions and recommendations that we hope will facilitate conduct of consistent approaches to collaborative efforts towards advancing our understanding of the vaginal microbiota and its impact on human health...
  7. pmc Relationship of specific vaginal bacteria and bacterial vaginosis treatment failure in women who have sex with women
    Jeanne M Marrazzo
    University of Washington and the Fred Hutchinson Cancer Research Center, Seattle, Washington, USA
    Ann Intern Med 149:20-8. 2008
    ..Bacterial vaginosis frequently persists after treatment. The role of newly defined bacterial vaginosis-associated bacteria (BVAB), which have a specificity for this condition of 97% or greater, has not been assessed...
  8. pmc More than meets the eye: associations of vaginal bacteria with gram stain morphotypes using molecular phylogenetic analysis
    Sujatha Srinivasan
    Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
    PLoS ONE 8:e78633. 2013
    ..Gram-negative rods designated Mobiluncus morphotypes on Gram stain are more likely BVAB1. These findings provide a clearer picture of the bacteria associated with morphotypes on vaginal Gram stain. ..
  9. pmc Temporal variability of human vaginal bacteria and relationship with bacterial vaginosis
    Sujatha Srinivasan
    Vaccine and Infectious Disease Institute, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
    PLoS ONE 5:e10197. 2010
    ..This study used PCR to assess the variability in concentrations of key vaginal bacteria in healthy women and the immediate response to antibiotic treatment in women with bacterial vaginosis (BV)...
  10. pmc Changes in vaginal bacterial concentrations with intravaginal metronidazole therapy for bacterial vaginosis as assessed by quantitative PCR
    David N Fredricks
    Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
    J Clin Microbiol 47:721-6. 2009
    ....
  11. ncbi request reprint Risk factors for cervicitis among women with bacterial vaginosis
    Jeanne M Marrazzo
    Department of Medicine, University of Washington, Seattle 98104, and Department of Pediatrics, Children s Hospital of Pittsburgh, PA, USA
    J Infect Dis 193:617-24. 2006
    ..Cervicitis commonly occurs in women with bacterial vaginosis (BV), often without concomitant chlamydial or gonococcal infection. The risk factors for cervicitis have not been described...
  12. pmc Effect of sexual activity on vaginal colonization with hydrogen peroxide-producing lactobacilli and Gardnerella vaginalis
    Caroline Mitchell
    Department of Obstetrics and Gynecology, University of Washington, Seattle, WA 98195, USA
    Sex Transm Dis 38:1137-44. 2011
    ..Bacterial vaginosis is associated with sexual activity, but mechanisms for this association are unclear...
  13. pmc Prevalence and risks for bacterial vaginosis in women who have sex with women
    Jeanne M Marrazzo
    Department of Medicine, University of Washington, Seattle, USA
    Sex Transm Dis 37:335-9. 2010
    ..Bacterial vaginosis (BV) is a common cause of vaginitis and, for unknown reasons, is common in lesbian and bisexual women. We defined risks for prevalent BV in lesbian and bisexual women with attention to detailed sexual risk history...
  14. ncbi request reprint Acceptability of urine-based screening for Chlamydia trachomatis in asymptomatic young men: a systematic review
    Jeanne M Marrazzo
    Department of Medicine, University of Washington, Seattle, Washington, USA
    Sex Transm Dis 35:S28-33. 2008
    ..Interventions to enhance uptake of testing in asymptomatic men should be developed and selected with underlying C. trachomatis population prevalence in mind...
  15. ncbi request reprint Bacterial vaginosis-associated bacteria in men: association of Leptotrichia/Sneathia spp. with nongonococcal urethritis
    Lisa E Manhart
    From the Department of Epidemiology, University of Washington, Seattle WA The Fred Hutchinson Cancer Research Center, Seattle, WA Children s National Medical Center, Washington, DC and Department of Medicine, University of Washington, Seattle, WA
    Sex Transm Dis 40:944-9. 2013
    ..Novel bacteria recently associated with bacterial vaginosis (BV) in women may be involved. We evaluated the association of idiopathic nongonococcal urethritis and 5 newly described BV-associated bacteria (BVAB)...
  16. pmc Diversity of human vaginal bacterial communities and associations with clinically defined bacterial vaginosis
    Brian B Oakley
    Program in Infectious Diseases, D3 100, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue N, Seattle, WA 98109 1024, USA
    Appl Environ Microbiol 74:4898-909. 2008
    ..The human vagina hosts many bacteria that are only distantly related to known species, and subjects with BV harbor particularly taxon-rich and diverse bacterial communities...
  17. pmc Distribution of genital Lactobacillus strains shared by female sex partners
    Jeanne M Marrazzo
    Department of Medicine, University of Washington, Seattle, Washington, USA
    J Infect Dis 199:680-3. 2009
    ..04) and increased bacterial vaginosis risk (odds ratio, 4.2; 95% confidence interval, 1.4-13.4). Of 31 couples monogamous for >3 months, rep-PCR fingerprints were identical in both members in 23 (77%)...
  18. ncbi request reprint Women's satisfaction with an intravaginal Lactobacillus capsule for the treatment of bacterial vaginosis
    Jeanne M Marrazzo
    Department of Medicine, University of Washington, Seattle, Washington, USA
    J Womens Health (Larchmt) 15:1053-60. 2006
    ..To assess women's satisfaction with a vaginal capsule containing human-derived, H(2)O(2)-producing Lactobacillus crispatus at completion of a randomized, placebo-controlled study for treatment of bacterial vaginosis (BV)...
  19. pmc Impact of patient characteristics on performance of nucleic acid amplification tests and DNA probe for detection of Chlamydia trachomatis in women with genital infections
    Jeanne M Marrazzo
    Department of Medicine, University of Washington, Seattle, WA, USA
    J Clin Microbiol 43:577-84. 2005
    ..These findings support expanded use of NAAT for screening and diagnosis of C. trachomatis in diverse clinical populations of women...
  20. pmc Bacterial communities in women with bacterial vaginosis: high resolution phylogenetic analyses reveal relationships of microbiota to clinical criteria
    Sujatha Srinivasan
    Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
    PLoS ONE 7:e37818. 2012
    ..We investigated the associations between the presence of individual bacterial species and clinical diagnostic characteristics of BV...
  21. ncbi request reprint Characterization of vaginal flora and bacterial vaginosis in women who have sex with women
    Jeanne M Marrazzo
    Department of Medicine, University of Washington, Seattle, WA 98104, USA
    J Infect Dis 185:1307-13. 2002
    ..These data support the hypothesis that sexual exchange of vaginal secretions is a possible mechanism for acquisition of BV...
  22. pmc Chlamydia trachomatis infection among women reporting sexual activity with women screened in Family Planning Clinics in the Pacific Northwest, 1997 to 2005
    Devika Singh
    Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle WA 98104, USA
    Am J Public Health 101:1284-90. 2011
    ....
  23. pmc Targeted PCR for detection of vaginal bacteria associated with bacterial vaginosis
    David N Fredricks
    Program in Infectious Diseases, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue, North, D3 100, Box 19024, Seattle, WA 98109 1024, USA
    J Clin Microbiol 45:3270-6. 2007
    ..PCR detection of one or more fastidious bacterial species is a more reliable indicator of BV than detection of bacteria, such as Gardnerella vaginalis, previously linked to BV, highlighting the potential of PCR for the diagnosis of BV...
  24. ncbi request reprint Molecular identification of bacteria associated with bacterial vaginosis
    David N Fredricks
    Program in Infectious Diseases, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    N Engl J Med 353:1899-911. 2005
    ..The cause of bacterial vaginosis remains poorly understood despite numerous studies based on cultures. Bacteria in microbial communities can be identified without cultivation by characterizing their ribosomal DNA (rDNA) sequences...
  25. pmc Sexual practices, risk perception and knowledge of sexually transmitted disease risk among lesbian and bisexual women
    Jeanne M Marrazzo
    Division of Allergy and Infectious Diseases, University of Washington, Seattle, WA, USA
    Perspect Sex Reprod Health 37:6-12. 2005
    ..However, few data on sexual practices or perceived STD risk among lesbians are available to guide development of interventions aimed at reducing the risk...
  26. ncbi request reprint Population-based outreach for Chlamydia screening in men: results from a randomized trial
    Delia Scholes
    Center for Health Studies, Group Health Cooperative, Seattle, WA 98101, USA
    Sex Transm Dis 34:837-9. 2007
    ..To evaluate the feasibility and efficacy of population-based outreach strategies to improve genital Chlamydia trachomatis (CT) screening in men...
  27. ncbi request reprint Chlamydial infections among female adolescents screened in juvenile detention centers in Washington State, 1998-2002
    Kathryn H Lofy
    Washington State Department of Health, Washington, USA
    Sex Transm Dis 33:63-7. 2006
    ..The objective of this study was to assess trends in Chlamydia trachomatis positivity and associated risk factors among detained female adolescents...
  28. ncbi request reprint Mucopurulent cervicitis: no longer ignored, but still misunderstood
    Jeanne M Marrazzo
    Division of Allergy and Infectious Diseases, University of Washington, Seattle, WA 98104, USA
    Infect Dis Clin North Am 19:333-49, viii. 2005
    ....
  29. ncbi request reprint Reproductive health history of lesbians: implications for care
    Jeanne M Marrazzo
    Department of Medicine, University of Washington, Seattle, Washngton, USA
    Am J Obstet Gynecol 190:1298-304. 2004
    ..We report lifetime pregnancy-related outcomes and hormonal contraception for 392 women who reported sexual activity with another woman in the preceding year...
  30. ncbi request reprint Management of women with cervicitis
    Jeanne M Marrazzo
    Department of Medicine, University of Washington, Seattle, WA 98104, USA
    Clin Infect Dis 44:S102-10. 2007
    ....
  31. ncbi request reprint Acceptability of urine-based screening for Chlamydia trachomatis to asymptomatic young men and their providers
    Jeanne M Marrazzo
    Department of Medicine, Division of Infectious Diseases, Harborview Medical Center, University of Washington, 325 Ninth Avenue, Seattle, WA 98104, USA
    Sex Transm Dis 34:147-53. 2007
    ..The objective of this study was to describe acceptability of urine chlamydia testing among asymptomatic men and providers' attitudes toward testing...
  32. ncbi request reprint Selective testing criteria for gonorrhea among young women screened for Chlamydial infection: contribution of race and geographic prevalence
    Lisa E Manhart
    Department of Epidemiology, University of Washington, Seattle, WA 98104, USA
    J Infect Dis 196:731-7. 2007
    ..Selective screening criteria have been widely implemented for genital Chlamydia trachomatis (CT) infections but have rarely been developed for Neisseria gonorrhoeae (GC) infection...
  33. ncbi request reprint Chlamydia trachomatis infection in asymptomatic men
    D Scott LaMontagne
    Center for Health Training, Seattle, Washington 98144, USA
    Am J Prev Med 24:36-42. 2003
    ..Established C. trachomatis screening programs for women have demonstrated the benefit of routine screening in reducing prevalence over time, but the yield and benefit of screening asymptomatic men are unclear...
  34. ncbi request reprint HIV prevention in clinical care settings: 2014 recommendations of the International Antiviral Society-USA Panel
    Jeanne M Marrazzo
    University of Washington, Seattle
    JAMA 312:390-409. 2014
    ..Emerging data warrant the integration of biomedical and behavioral recommendations for human immunodeficiency virus (HIV) prevention in clinical care settings...
  35. ncbi request reprint Screening and management of genital chlamydial infections
    Devika Singh
    Department of Global Health, Seattle STD HIV Prevention Training Center PTC, University of Washington, Box 359927, 325 Ninth Avenue, Seattle, WA 98104, USA Electronic address
    Infect Dis Clin North Am 27:739-53. 2013
    ..Practitioners are reminded to have a low threshold to offer testing and presumptive treatment to patients that are deemed at high risk of disease, particularly those who are challenging to engage in care...
  36. ncbi request reprint Evolving issues in understanding and treating bacterial vaginosis
    Jeanne M Marrazzo
    University of Washington, Department of Medicine, Harborview Medical Center, Division of Allergy and Infectious Diseases, 325 Ninth Avenue, Mailbox 359931, Seattle, WA 98104, USA
    Expert Rev Anti Infect Ther 2:913-22. 2004
    ..For these reasons, innovative approaches to therapy are urgently required...
  37. ncbi request reprint Prevalence and risk factors for infection with herpes simplex virus type-1 and -2 among lesbians
    Jeanne M Marrazzo
    Department of Medicine, University of Washington, Seattle, Washington, USA
    Sex Transm Dis 30:890-5. 2003
    ..Sexual transmission of bacterial and viral sexually transmitted disease has been reported between women. No data are available on seroprevalence of herpes simplex virus type-1 (HSV-1) and type-2 (HSV-2) among lesbians...
  38. ncbi request reprint The clinical and economic consequences of screening young men for genital chlamydial infection
    Rachel H S Ginocchio
    Department of Health Services, Maternal and Child Health, University of Washington, Seattle, Washington 98104, USA
    Sex Transm Dis 30:99-106. 2003
    ..Wide-scale application of urine-based screening of asymptomatic men for chlamydial infection has not been thoroughly assessed...
  39. ncbi request reprint Superficial hepatic capsular lesions in a systemically ill young woman
    Lindy S Klaff
    Department of Medicine, Harborview Medical Center, University of Washington, 325 Ninth Avenue, Seattle, WA 98104, USA
    Sex Transm Dis 34:139-40. 2007
  40. ncbi request reprint Predicting chlamydial and gonococcal cervical infection: implications for management of cervicitis
    Jeanne M Marrazzo
    Department of Medicine, University of Washington School of Medicine, Seattle, USA
    Obstet Gynecol 100:579-84. 2002
    ....
  41. pmc Barriers to infectious disease care among lesbians
    Jeanne M Marrazzo
    University of Washington, Seattle, Washington, USA
    Emerg Infect Dis 10:1974-8. 2004
    ..Education of lesbians and their care providers should counter assumptions that sex between women confers no risk for transmission of sexually transmitted infections, and lesbians should receive Pap smears according to current guidelines...
  42. ncbi request reprint Sexual tourism: implications for travelers and the destination culture
    Jeanne M Marrazzo
    Division of Allergy and Infectious Diseases, University of Washington, Harborview Medical Center, Seattle, WA 98104, USA
    Infect Dis Clin North Am 19:103-20. 2005
    ..Most of the relevant diagnostic tests are relatively affordable, and patient-centered risk-reduction counseling, once mastered, can be brief and easily integrated into the overall conversation about protecting oneself during travel...