Markovic D, Grammatopoulos D. Characterization of structural determinants of type 1 corticotropin releasing hormone (CRH) receptor signalling properties. Methods Mol Biol. 2010;634:285-307 pubmed publisher
..We identified a penta-amino acid cassette within the 29-amino acid insert of CRH-R1beta rich in positive charged amino acids (F(170)-R(174)), as an important structural determinant for the impaired cAMP response. ..