R Marchi

Summary

Publications

  1. doi A novel mutation in the FGB: c.1105C>T turns the codon for amino acid Bβ Q339 into a stop codon causing hypofibrinogenemia
    Rita Marchi
    Centro de Medicina Experimental, IVIC, Caracas, Bolivarian Republic of Venezuela
    Blood Cells Mol Dis 50:177-81. 2013
  2. doi Structure of fibrin network of two abnormal fibrinogens with mutations in the αC domain on the human dermal microvascular endothelial cells 1
    Rita Marchi
    Laboratorio Biología del Desarrollo de la Hemostasia, Centro de Medicina Experimental, Valencia, Bolivarian Republic of Venezuela
    Blood Coagul Fibrinolysis 22:706-11. 2011
  3. pmc A novel missense mutation in the FGB g. 3354 T>A (p. Y41N), fibrinogen Caracas VIII
    Rita Marchi
    Centro de Medicina Experimental, Laboratorio Biología del Desarrollo de la Hemostasia, Instituto Venezolano de Investigaciones Cientificas, Caracas, República Bolivariana de Venezuela
    Thromb Haemost 105:627-34. 2011
  4. ncbi Preliminary study of the fibrin structure in hypertensive, dyslipidemic and type 2 diabetic patients
    Rita Marchi-Cappelletti
    Instituto Venezolano de Investigaciones Cientificas, Centro de Medicina Experimental, Laboratorio de Fisiopatologia, Sección Biología del Desarrollo de la Hemostasia, Caracas, Venezuela
    Invest Clin 51:315-24. 2010
  5. ncbi [Effect of antiphospholipid antibodies on the formation and lysis of fibrin network in patients with recurrent miscarriage]
    Rita Marchi
    Centro de Medicina Experimental, Laboratorio Biología del Desarrollo de la Hemostasia, Instituto Venezolano de Investigaciones Cientificas, Caracas, Venezuela
    Invest Clin 52:35-47. 2011
  6. ncbi Invertebrate compounds acting on the hemostatic mechanism
    C L Arocha-Pinango
    Centro de Medicina Experimental, Instituto Venezolano de Investigaciones Cientificas, Caracas, Venezuela
    Blood Coagul Fibrinolysis 10:43-68. 1999

Collaborators

Detail Information

Publications6

  1. doi A novel mutation in the FGB: c.1105C>T turns the codon for amino acid Bβ Q339 into a stop codon causing hypofibrinogenemia
    Rita Marchi
    Centro de Medicina Experimental, IVIC, Caracas, Bolivarian Republic of Venezuela
    Blood Cells Mol Dis 50:177-81. 2013
    ..Electrospray ionization mass spectrometry (ESI MS) presented normal sialylation of the oligosaccharide chains, and liver function tests showed no evidence of liver dysfunction that might explain the functional abnormalities...
  2. doi Structure of fibrin network of two abnormal fibrinogens with mutations in the αC domain on the human dermal microvascular endothelial cells 1
    Rita Marchi
    Laboratorio Biología del Desarrollo de la Hemostasia, Centro de Medicina Experimental, Valencia, Bolivarian Republic of Venezuela
    Blood Coagul Fibrinolysis 22:706-11. 2011
    ..The structure of normal and patient clots performed in the absence of cells resembled that observed far from the cell surface, concluding that Caracas V and Caracas I fibrin was modulated by the presence of endothelial cells...
  3. pmc A novel missense mutation in the FGB g. 3354 T>A (p. Y41N), fibrinogen Caracas VIII
    Rita Marchi
    Centro de Medicina Experimental, Laboratorio Biología del Desarrollo de la Hemostasia, Instituto Venezolano de Investigaciones Cientificas, Caracas, República Bolivariana de Venezuela
    Thromb Haemost 105:627-34. 2011
    ..These results demonstrate the significance of the amino terminal end of the β chain of fibrin in the polymerisation process and its consequences on the clot organisation on the surface of endothelial cells...
  4. ncbi Preliminary study of the fibrin structure in hypertensive, dyslipidemic and type 2 diabetic patients
    Rita Marchi-Cappelletti
    Instituto Venezolano de Investigaciones Cientificas, Centro de Medicina Experimental, Laboratorio de Fisiopatologia, Sección Biología del Desarrollo de la Hemostasia, Caracas, Venezuela
    Invest Clin 51:315-24. 2010
    ..0015. Our results suggest that the fibrin structure was altered in DL and T2D patients, probably due to the increased cholesterol and glycation, respectively...
  5. ncbi [Effect of antiphospholipid antibodies on the formation and lysis of fibrin network in patients with recurrent miscarriage]
    Rita Marchi
    Centro de Medicina Experimental, Laboratorio Biología del Desarrollo de la Hemostasia, Instituto Venezolano de Investigaciones Cientificas, Caracas, Venezuela
    Invest Clin 52:35-47. 2011
    ..The changes observed in the fibrin polymerization and lysis process of women with RM without APS and LA seem to be related to their higher fibrinogen levels, while the increased plasmin generation was related to the patients' morbidity...
  6. ncbi Invertebrate compounds acting on the hemostatic mechanism
    C L Arocha-Pinango
    Centro de Medicina Experimental, Instituto Venezolano de Investigaciones Cientificas, Caracas, Venezuela
    Blood Coagul Fibrinolysis 10:43-68. 1999
    ..Some of these components have been well characterized, cloned and prepared in recombinant form, and seem to be very promising from the therapeutic point of view...