William R Marchand

Summary

Publications

  1. pmc Self-referential thinking, suicide, and function of the cortical midline structures and striatum in mood disorders: possible implications for treatment studies of mindfulness-based interventions for bipolar depression
    William R Marchand
    Research Service, George E Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, UT 84148, USA
    Depress Res Treat 2012:246725. 2012
  2. doi request reprint Abnormal functional connectivity of the medial cortex in euthymic bipolar II disorder
    William R Marchand
    George E Wahlen Veterans Affairs Medical Center, 500 Foothill Drive, Salt Lake City, UT 84148, USA University of Utah, 201 Presidents Circle, Salt Lake City, UT 84112, USA Electronic address
    Prog Neuropsychopharmacol Biol Psychiatry 51:28-33. 2014
  3. doi request reprint Striatal circuit function is associated with prior self-harm in remitted major depression
    William R Marchand
    George E Wahlen Veterans Affairs Medical Center, 500 Foothill Drive, Salt Lake City, UT 84148, USA University of Utah, 201 Presidents Circle, Salt Lake City, UT 84112, USA Electronic address
    Neurosci Lett 557:154-8. 2013
  4. ncbi request reprint Differences in functional connectivity in major depression versus bipolar II depression
    William R Marchand
    George E Wahlen Veterans Affairs Medical Center, VHASLCHCS 116 OP, 500 Foothill Drive, Salt Lake City, UT 84148, USA
    J Affect Disord 150:527-32. 2013
  5. doi request reprint Functional architecture of the cortico-basal ganglia circuitry during motor task execution: correlations of strength of functional connectivity with neuropsychological task performance among female subjects
    William R Marchand
    George E Wahlen Veterans Affairs Medical Center, Salt Lake City, Utah, USA
    Hum Brain Mapp 34:1194-207. 2013
  6. doi request reprint Mindfulness meditation practices as adjunctive treatments for psychiatric disorders
    William R Marchand
    George E Wahlen Veterans Administration Medical Center, 500 Foothill, Salt Lake City, UT 84148, USA
    Psychiatr Clin North Am 36:141-52. 2013
  7. doi request reprint Mindfulness-based stress reduction, mindfulness-based cognitive therapy, and Zen meditation for depression, anxiety, pain, and psychological distress
    William R Marchand
    George E Wahlen VAMC and University of Utah, Salt Lake City, USA
    J Psychiatr Pract 18:233-52. 2012
  8. doi request reprint Striatal and cortical midline circuits in major depression: implications for suicide and symptom expression
    William R Marchand
    George E Wahlen Veterans Affairs Medical Center, 500 Foothill Drive, Salt Lake City, UT 84148, USA
    Prog Neuropsychopharmacol Biol Psychiatry 36:290-9. 2012
  9. doi request reprint Aberrant emotional processing in posterior cortical midline structures in bipolar II depression
    William R Marchand
    George E Wahlen Veterans Affairs Medical Center, 500 Foothill Blvd, Salt Lake City, UT 84148, United States
    Prog Neuropsychopharmacol Biol Psychiatry 35:1729-37. 2011
  10. doi request reprint Striatal and cortical midline activation and connectivity associated with suicidal ideation and depression in bipolar II disorder
    William R Marchand
    George E Wahlen Veterans Affairs Medical Center, Salt Lake City, UT, USA
    J Affect Disord 133:638-45. 2011

Collaborators

Detail Information

Publications22

  1. pmc Self-referential thinking, suicide, and function of the cortical midline structures and striatum in mood disorders: possible implications for treatment studies of mindfulness-based interventions for bipolar depression
    William R Marchand
    Research Service, George E Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, UT 84148, USA
    Depress Res Treat 2012:246725. 2012
    ..Thus, combining studies of mindfulness interventions targeting abnormal self-referential thinking with functional imaging of CMS and striatal function may help delineate the neurobiological mechanisms of action of these treatments...
  2. doi request reprint Abnormal functional connectivity of the medial cortex in euthymic bipolar II disorder
    William R Marchand
    George E Wahlen Veterans Affairs Medical Center, 500 Foothill Drive, Salt Lake City, UT 84148, USA University of Utah, 201 Presidents Circle, Salt Lake City, UT 84112, USA Electronic address
    Prog Neuropsychopharmacol Biol Psychiatry 51:28-33. 2014
    ..Future studies should address whether these circuits contribute to relapse of illness. Our results also suggest the possibility that aberrations of superior frontal circuitry may impact default mode network and cognitive processes. ..
  3. doi request reprint Striatal circuit function is associated with prior self-harm in remitted major depression
    William R Marchand
    George E Wahlen Veterans Affairs Medical Center, 500 Foothill Drive, Salt Lake City, UT 84148, USA University of Utah, 201 Presidents Circle, Salt Lake City, UT 84112, USA Electronic address
    Neurosci Lett 557:154-8. 2013
    ..Our results also indicate that both striatal and CMS circuit dysfunction persists in the euthymic state of recurrent major depression and thus may represent trait pathology...
  4. ncbi request reprint Differences in functional connectivity in major depression versus bipolar II depression
    William R Marchand
    George E Wahlen Veterans Affairs Medical Center, VHASLCHCS 116 OP, 500 Foothill Drive, Salt Lake City, UT 84148, USA
    J Affect Disord 150:527-32. 2013
    ..One first step towards developing diagnostic methodology is determining whether brain function as assessed by functional MRI (fMRI) and functional connectivity analyses might differentiate the two disorders...
  5. doi request reprint Functional architecture of the cortico-basal ganglia circuitry during motor task execution: correlations of strength of functional connectivity with neuropsychological task performance among female subjects
    William R Marchand
    George E Wahlen Veterans Affairs Medical Center, Salt Lake City, Utah, USA
    Hum Brain Mapp 34:1194-207. 2013
    ..Finally, output (thalamus to cortex) feedback was only correlated with motor planning. This result suggests circuit processes may be more relevant for future behaviors than the execution of the current task...
  6. doi request reprint Mindfulness meditation practices as adjunctive treatments for psychiatric disorders
    William R Marchand
    George E Wahlen Veterans Administration Medical Center, 500 Foothill, Salt Lake City, UT 84148, USA
    Psychiatr Clin North Am 36:141-52. 2013
    ..This review provides information needed by clinicians to help patients maximize the benefits of mindfulness training and develop an enduring meditation practice...
  7. doi request reprint Mindfulness-based stress reduction, mindfulness-based cognitive therapy, and Zen meditation for depression, anxiety, pain, and psychological distress
    William R Marchand
    George E Wahlen VAMC and University of Utah, Salt Lake City, USA
    J Psychiatr Pract 18:233-52. 2012
    ..MBSR is beneficial for general psychological health and stress management in those with medical and psychiatric illness as well as in healthy individuals. Finally, MBSR and Zen meditation have a role in pain management...
  8. doi request reprint Striatal and cortical midline circuits in major depression: implications for suicide and symptom expression
    William R Marchand
    George E Wahlen Veterans Affairs Medical Center, 500 Foothill Drive, Salt Lake City, UT 84148, USA
    Prog Neuropsychopharmacol Biol Psychiatry 36:290-9. 2012
    ..The aim of this study was to identify striatal-CMS circuits associated with current depression severity and suicidal ideation (SI) as well as a history of self-harm...
  9. doi request reprint Aberrant emotional processing in posterior cortical midline structures in bipolar II depression
    William R Marchand
    George E Wahlen Veterans Affairs Medical Center, 500 Foothill Blvd, Salt Lake City, UT 84148, United States
    Prog Neuropsychopharmacol Biol Psychiatry 35:1729-37. 2011
    ..Further investigations of CMS function in bipolar spectrum disorders are warranted...
  10. doi request reprint Striatal and cortical midline activation and connectivity associated with suicidal ideation and depression in bipolar II disorder
    William R Marchand
    George E Wahlen Veterans Affairs Medical Center, Salt Lake City, UT, USA
    J Affect Disord 133:638-45. 2011
    ..Considerable evidence implicates dysfunction of striatal and cortical midline structure (CMS) circuitry in mood disorders. Whether such aberrations exist in bipolar II depression is unknown...
  11. doi request reprint Striatal structure and function in mood disorders: a comprehensive review
    William R Marchand
    Department of Veterans Affairs, VISN 19 MIRECC, 5500 Foothill, Salt Lake City, UT 84148, USA
    Bipolar Disord 12:764-85. 2010
    ..Recent functional imaging studies have greatly expanded this body of research. The aim of this review is to provide a comprehensive and critical appraisal of the relevant literature...
  12. doi request reprint Age-related changes of the functional architecture of the cortico-basal ganglia circuitry during motor task execution
    William R Marchand
    George E Wahlen Veterans Affairs Medical Center, 500 Foothill, Salt Lake City, UT 84148, USA
    Neuroimage 55:194-203. 2011
    ..Further, the methods employed will likely be useful for future studies aimed at disambiguating age-related versus illness progression changes associated with neuropsychiatric disorders that involve the cortico-basal ganglia circuitry...
  13. doi request reprint Cortico-basal ganglia circuitry: a review of key research and implications for functional connectivity studies of mood and anxiety disorders
    William R Marchand
    George E Wahlen Department of Veterans Affairs Medical Center, VHASLCHCS 151, 500 Foothill, Salt Lake City, UT 84148, USA
    Brain Struct Funct 215:73-96. 2010
    ..These are presented as models of circuit function, which may be particularly relevant to future investigations using neuroimaging and functional connectivity analyses...
  14. doi request reprint Reliability of fMRI motor tasks in structures of the corticostriatal circuitry: implications for future studies and circuit function
    James N Lee
    Department of Veterans Affairs VISN 19 MIRECC, Salt Lake City, UT, USA
    Neuroimage 49:1282-8. 2010
    ..Finally, these results suggest that the corticostriatal circuitry exhibit individualized responses to motor adaptation...
  15. doi request reprint Putamen coactivation during motor task execution
    William R Marchand
    Department of Veterans Affairs, VISN 19 MIRECC, Salt Lake City, Utah 84148, USA
    Neuroreport 19:957-60. 2008
    ..These findings suggest that the two corticostriatal circuits are functionally integrated. New circuit models based on functional connectivity may need to be developed...
  16. doi request reprint An fMRI motor activation paradigm demonstrates abnormalities of putamen activation in females with panic disorder
    William R Marchand
    Department of Veterans Affairs VISN 19 MIRECC, Salt Lake City, Utah 84148, USA
    J Affect Disord 116:121-5. 2009
    ..The neurobiology of panic disorder is incompletely understood. The aim of this study was to determine if functional abnormalities of the putamen occur in panic disorder...
  17. ncbi request reprint A functional MRI study of a paced motor activation task to evaluate frontal-subcortical circuit function in bipolar depression
    William R Marchand
    VISN 19 MIRECC, George E Wahlen Veterans Affairs Medical Center, Salt Lake City, Utah, USA
    Psychiatry Res 155:221-30. 2007
    ..Further, it suggests that the use of both a cognitive and motor task in the same study provides useful information about brain function. Finally, it supports the literature implicating FSC circuit abnormalities in bipolar disorder...
  18. doi request reprint Aberrant functional connectivity of cortico-basal ganglia circuits in major depression
    William R Marchand
    George E Wahlen Veterans Affairs Medical Center, 500 Foothill Drive, Salt Lake City, UT 84148, USA
    Neurosci Lett 514:86-90. 2012
    ....
  19. ncbi request reprint Motor deactivation in the human cortex and basal ganglia
    William R Marchand
    Department of Veterans Affairs, VISN 19 MIRECC, and University of Utah, Salt Lake City, UT 84148, USA
    Neuroimage 38:538-48. 2007
    ..Finally, we found no evidence of basal ganglia circuit deactivation, which suggests that the two-pathway hypothesis of frontal-subcortical circuit function may be incomplete...
  20. ncbi request reprint A preliminary study of the effect of a diagnosis of concussion on PTSD symptoms and other psychiatric variables at the time of treatment seeking among veterans
    Jennifer Romesser
    The George E Wahlen Veterans Affairs Medical Center, 500 Foothill, Salt Lake City, UT 84148, USA
    Mil Med 176:246-52. 2011
    ..If replicated, these results may guide the design of more effective interventions for veterans who receive diagnoses of PTSD and concussion...
  21. ncbi request reprint New models of frontal-subcortical skeletomotor circuit pathology in tardive dyskinesia
    William R Marchand
    George E Wahlen VAMC and the University of Utah, Salt Lake City, 84148, USA
    Neuroscientist 12:186-98. 2006
    ..Furthermore, this information may contribute to a more complete understanding of normal skeletomotor circuit function and the role of circuit pathology in numerous neuropsychiatric conditions...
  22. ncbi request reprint Clinical characteristics and health service use of veterans with comorbid bipolar disorder and PTSD
    John W Thatcher
    Department of Mental Health, George E Wahlen Department of Veterans Affairs Medical Center, 500 Foothill Blvd, Salt Lake City, UT 84148, USA
    Psychiatr Serv 58:703-7. 2007
    ..This study aimed to increase the understanding of the clinical characteristics and utilization of health services among veterans with comorbid bipolar disorder and posttraumatic stress disorder (PTSD)...