Champeil E, Cheng S, Huang B, Conchero Guisan M, Martinez T, Paz M, et al
. Synthesis of Mitomycin C and Decarbamoylmitomycin C N(2) deoxyguanosine-adducts. Bioorg Chem. 2016;65:90-9 pubmed publisher
..This suggests that the duplex DNA structure may stabilize/oriente the activated pro-drugs so that, with DMC, formation of the thermodynamically favored beta products are possible in a cellular environment. ..