Shirui Mao

Summary

Publications

  1. doi request reprint The depolymerization of sodium alginate by oxidative degradation
    Shirui Mao
    School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, China
    Pharm Dev Technol 17:763-9. 2012
  2. doi request reprint Chitosan-based formulations for delivery of DNA and siRNA
    Shirui Mao
    School of Pharmacy, Shenyang Pharmaceutical University, 110016 Shenyang, China
    Adv Drug Deliv Rev 62:12-27. 2010
  3. doi request reprint Bioadhesion and oral absorption of enoxaparin nanocomplexes
    Wei Sun
    School of Pharmacy, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenyang 110016, China
    Int J Pharm 386:275-81. 2010
  4. doi request reprint Exploration of hydrophobic modification degree of chitosan-based nanocomplexes on the oral delivery of enoxaparin
    Linlin Wang
    School of Pharmacy, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenyang 110016, China
    Eur J Pharm Sci 50:263-71. 2013
  5. doi request reprint Elucidation of release characteristics of highly soluble drug trimetazidine hydrochloride from chitosan-carrageenan matrix tablets
    Liang Li
    School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China
    J Pharm Sci 102:2644-54. 2013
  6. doi request reprint Drug release characteristics from chitosan-alginate matrix tablets based on the theory of self-assembled film
    Liang Li
    School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China
    Int J Pharm 450:197-207. 2013
  7. doi request reprint Self-assembled polyelectrolyte nanocomplexes between chitosan derivatives and enoxaparin
    Wei Sun
    Shenyang Pharmaceutical University, Shenyang, China
    Eur J Pharm Biopharm 69:417-25. 2008
  8. ncbi request reprint Recent advances in polymeric microspheres for parenteral drug delivery--part 2
    Shirui Mao
    Shenyang Pharmaceutical University, School of Pharmacy, China
    Expert Opin Drug Deliv 9:1209-23. 2012
  9. ncbi request reprint Uptake, transport and peroral absorption of fatty glyceride grafted chitosan copolymer-enoxaparin nanocomplexes: Influence of glyceride chain length
    Linlin Wang
    School of Pharmacy, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenyang 110016, China
    Acta Biomater 10:3675-85. 2014
  10. doi request reprint Design and in vitro evaluation of a film-controlled dosage form self-converted from monolithic tablet in gastrointestinal environment
    Tingting Zhang
    School of Pharmacy, Shenyang Pharmaceutical University, Wenhua Road 103, 110016 Shenyang, China
    J Pharm Sci 99:4678-90. 2010

Collaborators

Detail Information

Publications24

  1. doi request reprint The depolymerization of sodium alginate by oxidative degradation
    Shirui Mao
    School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, China
    Pharm Dev Technol 17:763-9. 2012
    ..In summary, this method is an effective and convenient approach for preparing low Mw oligosaccharides from sodium alginate and may be potentially useful for the drug delivery system design with alginate...
  2. doi request reprint Chitosan-based formulations for delivery of DNA and siRNA
    Shirui Mao
    School of Pharmacy, Shenyang Pharmaceutical University, 110016 Shenyang, China
    Adv Drug Deliv Rev 62:12-27. 2010
    ..In summary, the transfection efficiency of chitosan-based delivery systems can be adjusted by changing formulation-related parameters...
  3. doi request reprint Bioadhesion and oral absorption of enoxaparin nanocomplexes
    Wei Sun
    School of Pharmacy, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenyang 110016, China
    Int J Pharm 386:275-81. 2010
    ..In conclusion, the oral bioavailability of enoxaparin can be enhanced by improving the bioadhesive properties of PEC via the chemical modification of chitosan employed...
  4. doi request reprint Exploration of hydrophobic modification degree of chitosan-based nanocomplexes on the oral delivery of enoxaparin
    Linlin Wang
    School of Pharmacy, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenyang 110016, China
    Eur J Pharm Sci 50:263-71. 2013
    ..6% caused a decrease in oral absorption. In conclusion, oral bioavailability of enoxaparin can be enhanced by structure modification of the carriers and the bioavailability is hydrophobic modification degree dependent. ..
  5. doi request reprint Elucidation of release characteristics of highly soluble drug trimetazidine hydrochloride from chitosan-carrageenan matrix tablets
    Liang Li
    School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China
    J Pharm Sci 102:2644-54. 2013
    ..In conclusion, CS-λ-CG-based matrix tablets are quite promising as controlled-release drug carrier based on multiple mechanisms...
  6. doi request reprint Drug release characteristics from chitosan-alginate matrix tablets based on the theory of self-assembled film
    Liang Li
    School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China
    Int J Pharm 450:197-207. 2013
    ..The new insight into chitosan-alginate matrix tablets can help to broaden the application of this type of dosage forms...
  7. doi request reprint Self-assembled polyelectrolyte nanocomplexes between chitosan derivatives and enoxaparin
    Wei Sun
    Shenyang Pharmaceutical University, Shenyang, China
    Eur J Pharm Biopharm 69:417-25. 2008
    ..Oral absorption of the polyelectrolyte nanocomplexes will be studied in vivo...
  8. ncbi request reprint Recent advances in polymeric microspheres for parenteral drug delivery--part 2
    Shirui Mao
    Shenyang Pharmaceutical University, School of Pharmacy, China
    Expert Opin Drug Deliv 9:1209-23. 2012
    ..With recent advances in fabrication technologies, solvent free methods have demonstrated potential for the preparation of microspheres...
  9. ncbi request reprint Uptake, transport and peroral absorption of fatty glyceride grafted chitosan copolymer-enoxaparin nanocomplexes: Influence of glyceride chain length
    Linlin Wang
    School of Pharmacy, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenyang 110016, China
    Acta Biomater 10:3675-85. 2014
    ..In conclusion, oral absorption of enoxaparin can be further enhanced by using GM8 grafted chitosan copolymer as the carrier to form nanocomplexes. ..
  10. doi request reprint Design and in vitro evaluation of a film-controlled dosage form self-converted from monolithic tablet in gastrointestinal environment
    Tingting Zhang
    School of Pharmacy, Shenyang Pharmaceutical University, Wenhua Road 103, 110016 Shenyang, China
    J Pharm Sci 99:4678-90. 2010
    ..The in vivo behavior of this hydrophilic matrix system will be investigated...
  11. doi request reprint Effect of novel stabilizers--cationic polymers on the particle size and physical stability of poorly soluble drug nanocrystals
    Wei Sun
    School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, China
    Nanomedicine 8:460-7. 2012
    ..Physical stability of the nanocrystals with cationic polymers was remarkably improved. The in vivo antifungal efficacy of the nanocrystals was dependent on physicochemical properties and pH...
  12. doi request reprint Nanonization of itraconazole by high pressure homogenization: stabilizer optimization and effect of particle size on oral absorption
    Wei Sun
    School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, 110016, China
    J Pharm Sci 100:3365-73. 2011
    ..However, the AUC was not significantly affected by further reduction of the particle size within the nano-size range...
  13. doi request reprint A novel permeation enhancer: N-succinyl chitosan on the intranasal absorption of isosorbide dinitrate in rats
    Lidong Na
    School of Pharmacy, Shenyang Pharmaceutical University, 103 Wenhua Road, 32, Shenyang 110016, China
    Eur J Pharm Sci 48:301-6. 2013
    ..Taking both absorption enhancing and safety reason into account, we suggest NSCS is a promising intranasal absorption enhancer...
  14. ncbi request reprint Effect of chitosan structure properties and molecular weight on the intranasal absorption of tetramethylpyrazine phosphate in rats
    Dan Mei
    School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, China
    Eur J Pharm Biopharm 70:874-81. 2008
    ..Taking safety reason into account, chitosan 100 kDa is the most promising as an intranasal absorption enhancer...
  15. ncbi request reprint In vitro and in vivo evaluation of chitosan graft glyceryl monooleate as peroral delivery carrier of enoxaparin
    Linlin Wang
    School of Pharmacy, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenyang 110016, China
    Int J Pharm 471:391-9. 2014
    ..1%. In conclusion, CS-GO copolymer is a promising nanocarrier for enhancing the oral absorption of enoxaparin. ..
  16. doi request reprint Amphiphilic polymeric micelles as the nanocarrier for peroral delivery of poorly soluble anticancer drugs
    Ye Tian
    Shenyang Pharmaceutical University, School of Pharmacy, Shenyang, China
    Expert Opin Drug Deliv 9:687-700. 2012
    ..Studies on the formulation and oral delivery of such micelles have demonstrated their efficacy in enhancing drug uptake and absorption, and exhibit prolonged circulation time in vitro and in vivo...
  17. doi request reprint Comparison of different absorption enhancers on the intranasal absorption of isosorbide dinitrate in rats
    Lidong Na
    School of Pharmacy, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenyang 110016, China
    Int J Pharm 397:59-66. 2010
    ..Taking both enhancing effect and safety into account, we suggest poloxamer 188 is the most promising as an intranasal absorption enhancer...
  18. doi request reprint Recent advances in polymeric microspheres for parenteral drug delivery--part 1
    Shirui Mao
    Shenyang Pharmaceutical University, School of Pharmacy, Shenyang, China
    Expert Opin Drug Deliv 9:1161-76. 2012
    ..Polymeric microspheres have been established as a valuable parenteral drug delivery system for sustained release of therapeutic agents via subcutaneous or intramuscular injection...
  19. pmc Amphiphilic graft copolymer based on poly(styrene-co-maleic anhydride) with low molecular weight polyethylenimine for efficient gene delivery
    Xiaopin Duan
    School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, China
    Int J Nanomedicine 7:4961-72. 2012
    ..Fourier transform infrared spectrum, (1)H nuclear magnetic resonance, and gel permeation chromatography were used to characterize the graft copolymer...
  20. doi request reprint Carrageenan and its applications in drug delivery
    Liang Li
    School of Pharmacy, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenyang 110016, China
    Carbohydr Polym 103:1-11. 2014
    ..Furthermore, carrageenan has been used for tissue regeneration with therapeutic biomacromolecules and for cell delivery. Other potential applications and safety evaluation of carrageenan are still to be undertaken in the near future. ..
  21. ncbi request reprint Preparation and solidification of redispersible nanosuspensions
    Xin Zhang
    School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, 110016, China
    J Pharm Sci 103:2166-76. 2014
    ..2014 Wiley Periodicals, Inc. and the American Pharmacists Association J Pharm Sci 103:2166-2176, 2014. ..
  22. doi request reprint New strategies to improve the intranasal absorption of insulin
    Xiaopin Duan
    School of Pharmacy 32, Shenyang Pharmaceutical University, Wenhua Road 103, 110016 Shenyang, China
    Drug Discov Today 15:416-27. 2010
    ..It seems that bioadhesive delivery systems or water-insoluble powders with absorption enhancers are the most promising methods for intranasal delivery of insulin...
  23. ncbi request reprint Characterization of chitosan and its derivatives using asymmetrical flow field-flow-fractionation: a comparison with traditional methods
    Shirui Mao
    School of Pharmacy, Shenyang Pharmaceutical University, Wenhua Road 103, 110016 Shenyang, China
    J Pharm Biomed Anal 45:736-41. 2007
    ..In contrast, the influence was marginal when the molecular weight of chitosan was less than 50 kDa. The AF4-MALS was found to be a suitable method for the characterization of pure chitosans and trimethyl chitosans...
  24. ncbi request reprint Nanosuspensions of poorly water soluble drugs prepared by top-down technologies
    Xin Zhang
    School of Pharmacy, Shenyang Pharmaceutical University, 103 Wenhua Road, 110016, Shenyang, China
    Curr Pharm Des 20:388-407. 2014
    ..The different administration routes of nanosuspensions are also presented with their potential therapeutic benefits. ..