Braden J Manns

Summary

Publications

  1. ncbi request reprint The economics of end-stage renal disease care in Canada: incentives and impact on delivery of care
    Braden J Manns
    Department of Medicine, University of Calgary, Calgary, T2N 2T9, AB, Canada
    Int J Health Care Finance Econ 7:149-69. 2007
  2. ncbi request reprint What's next after fistula first: is an arteriovenous graft or central venous catheter preferable when an arteriovenous fistula is not possible?
    Matthew T James
    Department of Medicine, University of Calgary, Alberta, Canada
    Semin Dial 22:539-44. 2009
  3. doi request reprint Acute kidney injury following coronary angiography is associated with a long-term decline in kidney function
    Matthew T James
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    Kidney Int 78:803-9. 2010
  4. pmc Nocturnal hypoxia and loss of kidney function
    Sofia B Ahmed
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    PLoS ONE 6:e19029. 2011
  5. pmc Economic evaluation of increasing population rates of cardiac catheterization
    Fiona M Clement
    Department of Medicine, Faculty of Medicine, University of Calgary, Foothills Medical Centre North Tower, 9th Floor, 1403 29th Street NW, Calgary, AB T2N 2T9, Canada
    BMC Health Serv Res 11:324. 2011
  6. pmc Colorectal cancer screening for average-risk North Americans: an economic evaluation
    Steven J Heitman
    The Department of Medicine, University of Calgary, Alberta, Canada
    PLoS Med 7:e1000370. 2010
  7. pmc Association between drug insurance cost sharing strategies and outcomes in patients with chronic diseases: a systematic review
    Bikaramjit S Mann
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    PLoS ONE 9:e89168. 2014
  8. pmc Association of enrolment in primary care networks with diabetes care and outcomes among First Nations and low-income Albertans
    David J T Campbell
    Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada
    Open Med 6:e155-65. 2012
  9. pmc A systematic review of cost-sharing strategies used within publicly-funded drug plans in member countries of the organisation for economic co-operation and development
    Lianne Barnieh
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    PLoS ONE 9:e90434. 2014
  10. pmc The impact of nocturnal hemodialysis on sexual function
    Adam Bass
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    BMC Nephrol 13:67. 2012

Detail Information

Publications86

  1. ncbi request reprint The economics of end-stage renal disease care in Canada: incentives and impact on delivery of care
    Braden J Manns
    Department of Medicine, University of Calgary, Calgary, T2N 2T9, AB, Canada
    Int J Health Care Finance Econ 7:149-69. 2007
    ..This paper explains how ESRD care fits into the Canadian health care system, describes the epidemiology of ESRD in Canada, and offers economic explanations for international discrepancies...
  2. ncbi request reprint What's next after fistula first: is an arteriovenous graft or central venous catheter preferable when an arteriovenous fistula is not possible?
    Matthew T James
    Department of Medicine, University of Calgary, Alberta, Canada
    Semin Dial 22:539-44. 2009
    ..Specifically, we examine whether findings from previous studies are valid and applicable to patients for whom an AVF is not possible, and outline the need for future randomized clinical trials addressing this question...
  3. doi request reprint Acute kidney injury following coronary angiography is associated with a long-term decline in kidney function
    Matthew T James
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    Kidney Int 78:803-9. 2010
    ..8 ml/min following moderate to severe acute kidney injury. Thus, acute kidney injury following coronary angiography is associated with a sustained loss and a larger rate of future decline in kidney function...
  4. pmc Nocturnal hypoxia and loss of kidney function
    Sofia B Ahmed
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    PLoS ONE 6:e19029. 2011
    ..Although obstructive sleep apnea (OSA) is more common in patients with kidney disease, whether nocturnal hypoxia affects kidney function is unknown...
  5. pmc Economic evaluation of increasing population rates of cardiac catheterization
    Fiona M Clement
    Department of Medicine, Faculty of Medicine, University of Calgary, Foothills Medical Centre North Tower, 9th Floor, 1403 29th Street NW, Calgary, AB T2N 2T9, Canada
    BMC Health Serv Res 11:324. 2011
    ..However, such a strategy should only be undertaken if it is cost-effective...
  6. pmc Colorectal cancer screening for average-risk North Americans: an economic evaluation
    Steven J Heitman
    The Department of Medicine, University of Calgary, Alberta, Canada
    PLoS Med 7:e1000370. 2010
    ..The objective of this study was to perform an economic evaluation of CRC screening in average risk North American individuals considering all relevant screening modalities and current CRC treatment costs...
  7. pmc Association between drug insurance cost sharing strategies and outcomes in patients with chronic diseases: a systematic review
    Bikaramjit S Mann
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    PLoS ONE 9:e89168. 2014
    ..Patient cost sharing strategies such as copayments and deductibles are often employed to lower expenditures for prescription drug insurance plans, but the impact on health outcomes in these patients is unclear...
  8. pmc Association of enrolment in primary care networks with diabetes care and outcomes among First Nations and low-income Albertans
    David J T Campbell
    Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada
    Open Med 6:e155-65. 2012
    ..However, it is unknown whether First Nations individuals and those in lower SES groups experience these benefits...
  9. pmc A systematic review of cost-sharing strategies used within publicly-funded drug plans in member countries of the organisation for economic co-operation and development
    Lianne Barnieh
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    PLoS ONE 9:e90434. 2014
    ..We systematically reviewed the utilization of cost-sharing strategies and physician-directed prescribing regulations in publicly-funded formularies within member nations of the Organization of Economic Cooperation and Development (OECD)...
  10. pmc The impact of nocturnal hemodialysis on sexual function
    Adam Bass
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    BMC Nephrol 13:67. 2012
    ..We compared sexual activity and responses to sexual related questions in the Kidney Disease Quality of Life Short Form questionnaire among patients randomized to frequent nocturnal or thrice weekly conventional hemodialysis...
  11. pmc Evaluating the impact of a novel restricted reimbursement policy for quinolone antibiotics: a time series analysis
    Braden Manns
    Department of Medicine, Calgary, Alberta, Canada
    BMC Health Serv Res 12:290. 2012
    ..We conducted an observational study to determine the impact of this new formulary restriction policy on antimicrobial prescription rates as well as any clinical consequences...
  12. pmc A cluster randomized trial of an enhanced eGFR prompt in chronic kidney disease
    Braden Manns
    Department of Medicine, University of Calgary, Alberta, Canada
    Clin J Am Soc Nephrol 7:565-72. 2012
    ..This study sought to determine the effect of an enhanced eGFR laboratory prompt containing specific management recommendations, compared with standard eGFR reporting in CKD...
  13. pmc Enrolment in primary care networks: impact on outcomes and processes of care for patients with diabetes
    Braden J Manns
    Department of Medicine, University of Calgary, Calgary, Alta
    CMAJ 184:E144-52. 2012
    ..We sought to determine the association between enrolment in primary care networks and the care and outcomes of patients with diabetes...
  14. pmc The new FDA labeling for ESA--implications for patients and providers
    Braden J Manns
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    Clin J Am Soc Nephrol 7:348-53. 2012
    ..Although the US Food and Drug Administration labeling changes are based on the results of recent large randomized trials testing ESAs targeting near-normal hemoglobin levels, more specific guidance to clinicians would have been helpful...
  15. doi request reprint An economic evaluation of erythropoiesis-stimulating agents in CKD
    Fiona M Clement
    Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada
    Am J Kidney Dis 56:1050-61. 2010
    ..9 g/dL), intermediate (11-12 g/dL), or high (> 12 g/dL) hemoglobin level target compared with a strategy of managing anemia without ESAs...
  16. pmc Population based screening for chronic kidney disease: cost effectiveness study
    Braden Manns
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    BMJ 341:c5869. 2010
    ..To determine the cost effectiveness of one-off population based screening for chronic kidney disease based on estimated glomerular filtration rate...
  17. doi request reprint Associations between acute kidney injury and cardiovascular and renal outcomes after coronary angiography
    Matthew T James
    Department of Medicine, University of Calgary, Calgary, Canada
    Circulation 123:409-16. 2011
    ..Acute kidney injury (AKI) is associated with early mortality after percutaneous coronary revascularization procedures, but its prognostic relevance to long-term clinical outcomes remains controversial...
  18. doi request reprint Relation between kidney function, proteinuria, and adverse outcomes
    Brenda R Hemmelgarn
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    JAMA 303:423-9. 2010
    ..Although proteinuria is also associated with adverse outcomes, it is not used to refine risk estimates of adverse events in this current system...
  19. pmc Associations among estimated glomerular filtration rate, proteinuria, and adverse cardiovascular outcomes
    Aminu K Bello
    Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
    Clin J Am Soc Nephrol 6:1418-26. 2011
    ..Most studies of chronic kidney disease (CKD) and outcomes focus on mortality and ESRD, with limited data on other adverse outcomes. This study examined the associations among proteinuria, eGFR, and adverse cardiovascular (CV) events...
  20. doi request reprint Higher estimated glomerular filtration rates may be associated with increased risk of adverse outcomes, especially with concomitant proteinuria
    Marcello Tonelli
    Department of Public Health Sciences, University of Alberta, Edmonton, Alberta, Canada
    Kidney Int 80:1306-14. 2011
    ..We do not know, however, whether the finding at higher eGFR could be due to inadequacies of the eGFR formula at low serum creatinine levels...
  21. ncbi request reprint NSAID use and progression of chronic kidney disease
    Katherine Gooch
    Institute of Health Economics, Edmonton, Alberta, Canada
    Am J Med 120:280.e1-7. 2007
    ..Due to the high prevalence of both CKD and NSAID use in older adults, we sought to determine the association between NSAID use and the progression of CKD in an elderly community-based cohort...
  22. doi request reprint Nephrology visits and health care resource use before and after reporting estimated glomerular filtration rate
    Brenda R Hemmelgarn
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    JAMA 303:1151-8. 2010
    ..Laboratory reporting of estimated glomerular filtration rate (GFR) has been widely implemented, with limited evaluation...
  23. ncbi request reprint CKD and risk of hospitalization and death with pneumonia
    Matthew T James
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    Am J Kidney Dis 54:24-32. 2009
    ..The objective of this study is to determine the associations between estimated glomerular filtration rate (eGFR) and hospitalization or death with pneumonia...
  24. doi request reprint Glomerular filtration rate, proteinuria, and the incidence and consequences of acute kidney injury: a cohort study
    Matthew T James
    Department of Medicine, University of Calgary, Calgary, AB, Canada
    Lancet 376:2096-103. 2010
    ..We aimed to investigate how eGFR and proteinuria jointly modified the risks of acute kidney injury and subsequent adverse clinical outcomes...
  25. pmc Access to health care among status Aboriginal people with chronic kidney disease
    Song Gao
    Department of Medicine, Division of Nephrology, University of Calgary, Calgary, AB
    CMAJ 179:1007-12. 2008
    ..We determined whether access to care differed between status Aboriginal people (Aboriginal people registered under the federal Indian Act) and non-Aboriginal people with chronic kidney disease...
  26. doi request reprint Validating a case definition for chronic kidney disease using administrative data
    Paul E Ronksley
    Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada
    Nephrol Dial Transplant 27:1826-31. 2012
    ..The purpose of this study was to determine the validity of an algorithm derived from administrative data for identifying chronic kidney disease (CKD) compared to the reference standard of estimated glomerular filtration rate (eGFR)...
  27. doi request reprint Association of a change in erythropoiesis-stimulating agent dose during hospitalization and subsequent hemoglobin levels and transfusions in hemodialysis patients
    Ben C Wong
    University of Calgary, Calgary, Canada
    Am J Kidney Dis 62:947-52. 2013
    ..We sought to determine whether increases in ESA dose during hospital admission were associated with changes in transfusion requirement and risk of exceeding recommended hemoglobin targets...
  28. ncbi request reprint Risk of coronary events in people with chronic kidney disease compared with those with diabetes: a population-level cohort study
    Marcello Tonelli
    Department of Medicine, University of Alberta, Edmonton, Canada
    Lancet 380:807-14. 2012
    ..We assessed whether chronic kidney disease should be regarded as a coronary heart disease risk equivalent...
  29. pmc Validation of a case definition to define chronic dialysis using outpatient administrative data
    Fiona M Clement
    Department of Medicine, University of Calgary, 2500 University Dr NW, Calgary, Alberta, T2N 1N4, Canada
    BMC Med Res Methodol 11:25. 2011
    ..The objective of this study is to determine the validity of outpatient physician billing derived algorithms for defining chronic dialysis compared to a reference standard ESRD registry...
  30. pmc Association between routine and standardized blood pressure measurements and left ventricular hypertrophy among patients on hemodialysis
    Jaspreet Khangura
    Department of Medicine, University of British Columbia, Vancouver, Canada
    BMC Nephrol 11:13. 2010
    ..We sought to determine agreement between various blood pressure measurement methods, as well as identify which method was the strongest correlate of LV hypertrophy among patients on hemodialysis...
  31. ncbi request reprint Prevalence of chronic kidney disease and survival among aboriginal people
    Song Gao
    Department of Medicine, Division of Nephrology, University of Calgary, Calgary, Alberta, Canada
    J Am Soc Nephrol 18:2953-9. 2007
    ....
  32. pmc Lifetime risk of ESRD
    Tanvir Chowdhury Turin
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    J Am Soc Nephrol 23:1569-78. 2012
    ..These population-based estimates may assist individuals who make decisions regarding public health policy...
  33. doi request reprint The effect of nocturnal and conventional hemodialysis on markers of nutritional status: results from a randomized trial
    Melissa Schorr
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    J Ren Nutr 21:271-6. 2011
    ..More frequent dialysis may improve nutrition and remove dietary restrictions in hemodialysis (HD) patients. We present results from a trial comparing nutritional parameters between nocturnal hemodialysis (NHD) and conventional HD patients...
  34. doi request reprint Quality of care and mortality are worse in chronic kidney disease patients living in remote areas
    Diana Rucker
    Department of Medicine, University of Alberta, Alberta, Canada
    Kidney Int 79:210-7. 2011
    ....
  35. doi request reprint Prevention of dialysis catheter malfunction with recombinant tissue plasminogen activator
    Brenda R Hemmelgarn
    Department of Medicine, University of Calgary, Calgary, Alberta
    N Engl J Med 364:303-12. 2011
    ....
  36. ncbi request reprint The effects of nocturnal compared with conventional hemodialysis on mineral metabolism: A randomized-controlled trial
    Michael Walsh
    Department of Medicine, University of Calgary, Alberta, Canada
    Hemodial Int 14:174-81. 2010
    ..The effects of NHD on PTH are variable. The impact of these changes on long-term cardiovascular and bone-related outcomes requires further investigation...
  37. pmc Health care costs in people with diabetes and their association with glycemic control and kidney function
    Kerry A McBrien
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    Diabetes Care 36:1172-80. 2013
    ....
  38. pmc Renal outcomes associated with invasive versus conservative management of acute coronary syndrome: propensity matched cohort study
    Matthew T James
    Department of Medicine, University of Calgary, Foothills Medical Centre, 1403 29th St NW, Calgary, Alberta T2N 2T9, Canada
    BMJ 347:f4151. 2013
    ....
  39. doi request reprint Rates of treated and untreated kidney failure in older vs younger adults
    Brenda R Hemmelgarn
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    JAMA 307:2507-15. 2012
    ..Studies of kidney failure in older adults have focused on receipt of dialysis, which may underestimate the burden of disease if older people are less likely to receive treatment...
  40. ncbi request reprint Impact of anemia on hospitalization and mortality in older adults
    Bruce F Culleton
    Department of Medicine, University of Calgary, Foothills Hospital, Rm C210, 1403 29th St NW, Calgary, AB, Canada T2N 2T9
    Blood 107:3841-6. 2006
    ..Consideration should be given to redefine "normal" hemoglobin values in the elderly. Clinical trials are also necessary to determine whether anemia correction improves quality or quantity of life in this population...
  41. ncbi request reprint Association between multidisciplinary care and survival for elderly patients with chronic kidney disease
    Brenda R Hemmelgarn
    Department of Medicine, Community Health Schiences, University of Calgary, Calgary, Canada
    J Am Soc Nephrol 18:993-9. 2007
    ..The benefits of MDC and an assessment of their economic impact should be tested in a randomized, controlled trial...
  42. ncbi request reprint Differences in use of peritoneal dialysis and survival among East Asian, Indo Asian, and white ESRD patients in Canada
    Brenda R Hemmelgarn
    Department of Medicine, Division of Nephrology, University of Calgary, Canada
    Am J Kidney Dis 48:964-71. 2006
    ..Racial differences in health outcomes in general are well documented; however, few studies examined the impact of East Asian and Indo Asian race on choice of dialytic modality and survival among patients with end-stage renal disease (ESRD)...
  43. doi request reprint Risk of bloodstream infection in patients with chronic kidney disease not treated with dialysis
    Matthew T James
    Department of Medicine, University of Calgary, Foothills Medical Center, 1403 29th St NW, Calgary, AB T2N 2T9, Canada
    Arch Intern Med 168:2333-9. 2008
    ..Whether patients with chronic kidney disease who are not receiving dialysis are also at increased risk of bloodstream infection is less clear...
  44. ncbi request reprint Moving beyond the cost per quality-adjusted life year: modelling the budgetary impact and clinical outcomes associated with the use of sirolimus-eluting stents
    Fiona M Shrive
    Department of Community Health Sciences, University of Calgary, Canada
    Can J Cardiol 21:783-7. 2005
    ..Several issues that decision-makers and providers may wish to consider when making such funding decisions are discussed...
  45. ncbi request reprint Effect of frequent nocturnal hemodialysis vs conventional hemodialysis on left ventricular mass and quality of life: a randomized controlled trial
    Bruce F Culleton
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    JAMA 298:1291-9. 2007
    ..Morbidity and mortality rates in hemodialysis patients remain excessive. Alterations in the delivery of dialysis may lead to improved patient outcomes...
  46. pmc Estimated GFR and fracture risk: a population-based study
    Meghan J Elliott
    Departments of Medicine and Community Health Sciences, University of Calgary, Calgary, Alberta, Canada
    Clin J Am Soc Nephrol 8:1367-76. 2013
    ..This study sought to determine the association between estimated GFR (eGFR) and fracture rates...
  47. doi request reprint Chronic kidney disease and life expectancy
    Tanvir Chowdhury Turin
    Department of Medicine, University of Calgary, Calgary, Canada
    Nephrol Dial Transplant 27:3182-6. 2012
    ..Life expectancy is commonly used as an indicator of health and reflects disease burden in the population. The life expectancy for patients with lower levels of kidney function has not been reported...
  48. ncbi request reprint Use of the U.S. and U.K. scoring algorithm for the EuroQol-5D in an economic evaluation of cardiac care
    Fiona M Shrive
    Department of Community Health Sciences, Centre for Health and Policy Studies at the University of Calgary, Calgary, Alberta, Canada
    Med Care 45:269-73. 2007
    ..We recently published an economic evaluation assessing the use of drug-eluting stents in patients undergoing percutaneous coronary intervention (PCI)...
  49. pmc Cardiovascular effects of angiotensin converting enzyme inhibition or angiotensin receptor blockade in hemodialysis: a meta-analysis
    Davina J Tai
    Division of Nephrology, Foothills Medical Centre, 1403 29th Street NW, Calgary, Alberta, Canada, T2N 2T9
    Clin J Am Soc Nephrol 5:623-30. 2010
    ..This meta-analysis was performed to determine whether angiotensin converting enzyme inhibitors (ACEIs) or angiotensin receptor blockers (ARBs) reduce fatal and nonfatal CV events and left ventricular (LV) mass in patients receiving HD...
  50. doi request reprint Association between GFR, proteinuria, and adverse outcomes among White, Chinese, and South Asian individuals in Canada
    Joslyn Conley
    Department of Medicine, University of Calgary, Alberta, Canada
    Am J Kidney Dis 59:390-9. 2012
    ..We investigated the association between proteinuria, estimated glomerular filtration rate (eGFR), and risk of mortality and kidney failure in white, Chinese, and South Asian populations...
  51. pmc Overview of the Alberta Kidney Disease Network
    Brenda R Hemmelgarn
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    BMC Nephrol 10:30. 2009
    ..The Alberta Kidney Disease Network is a collaborative nephrology research organization based on a central repository of laboratory and administrative data from the Canadian province of Alberta...
  52. ncbi request reprint The impact of selecting a high hemoglobin target level on health-related quality of life for patients with chronic kidney disease: a systematic review and meta-analysis
    Fiona M Clement
    Departments of Community Health Sciences and Medicine, Centre for Health and Policy Studies, University of Calgary, Calgary, Alberta, Canada
    Arch Intern Med 169:1104-12. 2009
    ..0-12.0 g/dL) and high hemoglobin target levels (>12.0 g/dL) and performed a meta-analysis of all available 36-item short-form (SF-36) RCT data...
  53. ncbi request reprint Evaluation of an education intervention to increase the pursuit of living kidney donation: a randomized controlled trial
    Lianne Barnieh
    University of Calgary, Calgary, Alberta, Canada
    Prog Transplant 21:36-42. 2011
    ..Many transplant candidates have concerns about living donation...
  54. pmc Factors associated with initiation of chronic renal replacement therapy for patients with kidney failure
    Labib I Faruque
    Department of Medicine, University of Alberta, Edmonton, AB, Canada
    Clin J Am Soc Nephrol 8:1327-35. 2013
    ..Patients with kidney failure sometimes do not receive chronic renal replacement therapy (RRT), even though this may reduce their life expectancy. This study aimed to identify factors associated with initiation of chronic RRT...
  55. ncbi request reprint Self-reported financial barriers to care among patients with cardiovascular-related chronic conditions
    David J T Campbell
    University of Calgary, Calgary, Alberta
    Health Rep 25:3-12. 2014
    ..Failure to meet these targets may be due to a variety of barriers. This article examines self-reported financial barriers to health care among people with cardiovascular-related chronic conditions...
  56. doi request reprint Prevalence of adenomas and colorectal cancer in average risk individuals: a systematic review and meta-analysis
    Steven J Heitman
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    Clin Gastroenterol Hepatol 7:1272-8. 2009
    ..The objectives of our study were to determine the pooled prevalence of adenomas and colorectal cancer, as well as nonadvanced and advanced adenomas, among average risk North Americans...
  57. pmc Prevention of catheter lumen occlusion with rT-PA versus heparin (Pre-CLOT): study protocol of a randomized trial [ISRCTN35253449]
    Brenda R Hemmelgarn
    Division of Nephrology, Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    BMC Nephrol 7:8. 2006
    ..The Prevention of Catheter Lumen Occlusion with rt-PA versus Heparin (PreCLOT) study will determine if use of weekly rt-PA, compared to regular heparin, as a catheter locking solution, will decrease the risk of catheter malfunction...
  58. pmc Comorbidities do not influence primary fistula success in incident hemodialysis patients: a prospective study
    Wenjie Wang
    Division of Nephrology, University of Calgary, Foothills Medical Center, Calgary, Canada
    Clin J Am Soc Nephrol 3:78-84. 2008
    ..Concern about primary fistula failure may contribute to the underuse of arteriovenous fistula. The objective of this study was to investigate the baseline clinical parameters associated with primary fistula success...
  59. pmc Economic evaluation of sirolimus-eluting stents
    Fiona M Shrive
    Department of Community Health Sciences, University of Calgary, Calgary, Alta
    CMAJ 172:345-51. 2005
    ..Given that sirolimus-eluting stents cost about 4 times as much as conventional stents, and considering the volume of PCI procedures, the decision to use sirolimus-eluting stents has large economic implications...
  60. doi request reprint Ascorbic acid for anemia management in hemodialysis patients: a systematic review and meta-analysis
    Vinay Deved
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    Am J Kidney Dis 54:1089-97. 2009
    ..Ascorbic acid is believed to improve anemia in patients with end-stage renal disease, but its overall effectiveness is unclear...
  61. doi request reprint Nonmedical costs of colorectal cancer screening with the fecal occult blood test and colonoscopy
    Steven J Heitman
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    Clin Gastroenterol Hepatol 6:912-917.e1. 2008
    ..The nonmedical costs of colorectal cancer screening are unknown. However, they might influence screening uptake and impact the cost-effectiveness of colorectal cancer screening modalities...
  62. doi request reprint Knowledge translation for nephrologists: strategies for improving the identification of patients with proteinuria
    Brenda R Hemmelgarn
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    J Nephrol 25:933-43. 2012
    ..These considerations are relevant for dissemination and implementation of guidelines on other topics and in other clinical settings...
  63. doi request reprint Nocturnal hemodialysis does not improve overall measures of quality of life compared to conventional hemodialysis
    Braden J Manns
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    Kidney Int 75:542-9. 2009
    ....
  64. doi request reprint The impact of using different costing methods on the results of an economic evaluation of cardiac care: microcosting vs gross-costing approaches
    Fiona M Clement Nee Shrive
    Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada
    Health Econ 18:377-88. 2009
    ..Published guidelines on the conduct of economic evaluations provide little guidance regarding the use and potential bias of the different costing methods...
  65. ncbi request reprint Defining the optimal treatment of locally advanced esophageal cancer: a systematic review and decision analysis
    Andrew J Graham
    Department of Surgery, Division of Thoracic Surgery, University of Calgary, Institute of Health Economics, Calgary, Alberta, Canada
    Ann Thorac Surg 83:1257-64. 2007
    ..The objective of this study was to combine systematic review and decision analytic techniques to determine the optimal treatment strategy for patients with locally advanced esophageal cancer...
  66. ncbi request reprint Rapid evaluation after high-risk TIA is associated with lower stroke risk
    Caren M Wu
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    Can J Neurol Sci 36:450-5. 2009
    ..We describe the clinical outcomes and costs for high risk TIA patients who received care in a 'rapid evaluation unit', and compare these to a historical 'high-risk' cohort...
  67. ncbi request reprint Dialysis adequacy and health related quality of life in hemodialysis patients
    Braden J Manns
    Department of Medicine, University of Calgary, Alberta, Canada
    ASAIO J 48:565-9. 2002
    ..Dialysis adequacy was significantly associated with HRQOL in hemodialysis patients. Controlled studies that examine the effect of increasing Kt/V on HRQOL are needed...
  68. pmc A multi-region assessment of population rates of cardiac catheterization and yield of high-risk coronary artery disease
    Fiona M Clement
    Department of Medicine, Faculty of Medicine, University of Calgary, Foothills Medical Centre North Tower, 9th Floor, 1403 29th Street NW, Calgary, AB T2N 2T9, Canada
    BMC Health Serv Res 11:323. 2011
    ....
  69. pmc The effects of nocturnal hemodialysis compared to conventional hemodialysis on change in left ventricular mass: rationale and study design of a randomized controlled pilot study
    Michael Walsh
    Department of Medicine, University of Calgary, Calgary, Canada
    BMC Nephrol 7:2. 2006
    ..We have undertaken a multi-center RCT in hemodialysis patients comparing the effect of NHD to CvHD on left ventricular (LV) mass, as measured by cardiac magnetic resonance imaging (cMR)...
  70. ncbi request reprint The cost-effectiveness of maintaining higher hemoglobin targets with erythropoietin in hemodialysis patients
    Marcello Tonelli
    Division of Nephrology, University of Alberta, Edmonton, Alberta, Canada
    Kidney Int 64:295-304. 2003
    ..There is uncertainty regarding the appropriate target hemoglobin level in hemodialysis patients treated with erythropoietin (EPO)...
  71. ncbi request reprint Adapting the Charlson Comorbidity Index for use in patients with ESRD
    Brenda R Hemmelgarn
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    Am J Kidney Dis 42:125-32. 2003
    ..The purpose of this study is to assess the validity of the Charlson index in incident dialysis patients and modify the index for use specifically in this patient population...
  72. ncbi request reprint The epidemiology of severe sepsis syndrome and its treatment with recombinant human activated protein C
    Christopher James Doig
    Department of Critical Care Medicine, Faculty of Medicine, University of Calgary, Calgary AB, T2N 2T9, Canada
    Expert Opin Pharmacother 4:1789-99. 2003
    ..This review discusses the epidemiology of sepsis, preclinical and clinical evidence supporting the use of rhAPC use, controversies about the evidence of efficacy in severe sepsis syndrome and cost-effectiveness data...
  73. ncbi request reprint Using effectiveness and cost-effectiveness to make drug coverage decisions: a comparison of Britain, Australia, and Canada
    Fiona M Clement
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    JAMA 302:1437-43. 2009
    ..This study describes how that evidence has been used across 3 jurisdictions (Australia, Canada, and Britain) that have been at the forefront of evidence-based coverage internationally...
  74. doi request reprint Barriers to living kidney donation identified by eligible candidates with end-stage renal disease
    Lianne Barnieh
    Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada
    Nephrol Dial Transplant 26:732-8. 2011
    ..Among eligible transplant candidates with end-stage renal disease, only a minority receive a living donor kidney transplant (LDKT), suggesting that there are barriers to receipt of this optimal therapy...
  75. pmc An economic evaluation of venous thromboembolism prophylaxis strategies in critically ill trauma patients at risk of bleeding
    T Carter Chiasson
    Department of Biomedical Sciences, University of Calgary, Calgary, Canada
    PLoS Med 6:e1000098. 2009
    ..Currently, the optimal VTE prophylaxis strategy is unknown for trauma patients with a contraindication to pharmacological prophylaxis because of a risk of bleeding...
  76. ncbi request reprint Meta-analysis: antibiotics for prophylaxis against hemodialysis catheter-related infections
    Matthew T James
    University of Calgary, Calgary, and University of Alberta and Institute of Health Economics, Edmonton, Alberta, Canada
    Ann Intern Med 148:596-605. 2008
    ..Catheter-related infections cause morbidity and mortality in patients undergoing hemodialysis...
  77. ncbi request reprint The impact of education on chronic kidney disease patients' plans to initiate dialysis with self-care dialysis: a randomized trial
    Braden J Manns
    Division of Nephrology, Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    Kidney Int 68:1777-83. 2005
    ....
  78. pmc Relation between access blood flow and mortality in chronic hemodialysis patients
    Mohammed Al-Ghonaim
    Department of Medicine, University of Alberta, Edmonton, Canada
    Clin J Am Soc Nephrol 3:387-91. 2008
    ..Patients were followed from the date of Qa measurement until death; follow-up was discontinued at loss to follow-up, kidney transplantation, or end of study...
  79. ncbi request reprint Cost-effectiveness of hemofiltration to prevent contrast nephropathy in patients with chronic kidney disease
    Scott W Klarenbach
    Department of Medicine, Division of Nephrology, University of Alberta, Canada
    Crit Care Med 34:1044-51. 2006
    ..We sought to explore the potential scope and cost-effectiveness of this strategy...
  80. doi request reprint Nonmedical costs of colorectal cancer screening using CT colonography
    Steven J Heitman
    Department of Medicine, University of Calgary, 3280 Hospital Drive NW, Calgary, Alberta, Canada
    J Am Coll Radiol 7:943-8. 2010
    ..The purpose of this study was to determine the nonmedical costs of CTC...
  81. ncbi request reprint Mycophenolate mofetil for induction therapy of lupus nephritis: a systematic review and meta-analysis
    Michael Walsh
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    Clin J Am Soc Nephrol 2:968-75. 2007
    ..A systematic review and meta-analysis were performed to determine the risk for failure to induce remission of lupus nephritis in patients who were treated with mycophenolate mofetil compared with cyclophosphamide...
  82. ncbi request reprint Early risk of stroke after transient ischemic attack: a systematic review and meta-analysis
    Caren M Wu
    Department of Medicine, University of Calgary, Calgary, AB, Canada
    Arch Intern Med 167:2417-22. 2007
    ....
  83. ncbi request reprint An economic evaluation of activated protein C treatment for severe sepsis
    Braden J Manns
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    N Engl J Med 347:993-1000. 2002
    ....
  84. ncbi request reprint Economic evaluation in critical care medicine
    Heather L Cox
    Department of Surgery, University of Calgary and Calgary Health Region, Calgary, Alberta, Canada T2L 2K8
    J Crit Care 21:117-24. 2006
    ..This article highlights the need for randomized clinical trials and economic evaluations of therapies in critical care medicine for which the effect of the therapy on health outcomes and/or costs are unknown...
  85. doi request reprint The role of health economics within clinical research
    Braden J Manns
    Department of Medicine, University of Calgary, Calgary, Canada
    Methods Mol Biol 473:235-50. 2009
    ....
  86. ncbi request reprint Vitamin B12 decreases, but does not normalize, homocysteine and methylmalonic acid in end-stage renal disease: a link with glycine metabolism and possible explanation of hyperhomocysteinemia in end-stage renal disease
    Matthew Eric Hyndman
    Division of Nephrology, Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    Metabolism 52:168-72. 2003
    ..05). High-dose vitamin therapy significantly lowers, but does not normalize, MMA and tHcy levels. The MTHFR genotype, while influencing homocysteine levels, was not responsible for the majority of the elevation in plasma tHcy...