Weight loss and asthma control in severely obese asthmatic femalesMauro Maniscalco
Section of Respiratory Medicine, Hospital S Maria della Pietà Casoria, Naples, Italy
Respir Med 102:102-8. 2008
..The effects of consistent weight loss on asthma control are not well known. We investigated the effect of weight reduction induced by bariatric surgery on asthma control in severely obese asthmatic patients...
Exhaled nasal nitric oxide during humming: potential clinical tool in sinonasal disease?Mauro Maniscalco
Section of Respiratory Medicine, Hospital S Maria della Pietà, Casoria, Naples, Italy
Biomark Med 7:261-6. 2013
..The aim of this review is to discuss the basic concepts and clinical applications of nNO assessment during humming, which represents a simple and noninvasive method to approach sinonasal disease...
Early treatment with noninvasive positive pressure ventilation prolongs survival in Amyotrophic Lateral Sclerosis patients with nocturnal respiratory insufficiencyPierluigi Carratu
Institute of Pulmonary Disease, University of Bari, Bari, Italy
Orphanet J Rare Dis 4:10. 2009
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- Exhaled and arterial levels of endothelin-1 are increased and correlate with pulmonary systolic pressure in COPD with pulmonary hypertension
Pierluigi Carratu
Institute of Pulmonary Disease, University of Bari, Italy
BMC Pulm Med 8:20. 2008
..Endothelin-1 (ET-1) and Nitric Oxide (NO) are crucial mediators for establishing pulmonary artery hypertension (PAH). We tested the hypothesis that their imbalance might also occur in COPD patients with PAH...
- Association of Adams-Oliver syndrome with pulmonary arterio-venous malformation in the same family: a further support to the vascular hypothesis
Mauro Maniscalco
Section of Respiratory Medicine, Hospital S Maria della Pietà, Casoria, Naples, Italy
Am J Med Genet A 136:269-74. 2005
..Therefore, the role of screening for PAVM in clinical management of subjects with AOS should deserve further studies...
- Exhaled breath condensate as matrix for toluene detection: a preliminary study
M Maniscalco
Department of Respiratory Medicine, A O Monaldi, University Federico II of Naples, Naples, Italy
Biomarkers 11:233-40. 2006
..In conclusion, exhaled breath condensate is a promising matrix for toluene assessment, although its application in humans requires further investigations...
- Sounding airflow enhances aerosol delivery into the paranasal sinuses
M Maniscalco
Department of Pharmacology and Physiology, Karolinska Institute, Stockholm, Sweden
Eur J Clin Invest 36:509-13. 2006
..This is reflected by a high peak in nasally exhaled nitric oxide (NO) levels because NO accumulated in the sinuses is rapidly washed-out via the sinus ostia...
- Exhaled nitric oxide in severe obesity: effect of weight loss
Mauro Maniscalco
Section of Respiratory Medicine, Hospital S Maria della Pietà Casoria, Naples, Italy
Respir Physiol Neurobiol 156:370-3. 2007
..The relationship between exhaled NO, large body mass excess and decrease of resting lung volume in severe obesity deserves further studies...
- Right ventricular performance in severe obesity. Effect of weight loss
M Maniscalco
Section of Respiratory Medicine, Hospital S Maria della Pietà, Casoria, Largo delle Mimose 1, 80131 Naples, Italy
Eur J Clin Invest 37:270-5. 2007
..The aim of our study was to assess R-MPI in individuals with severe but uncomplicated obesity before and after a significant weight loss induced by bariatric surgery...
- Nitric oxide in upper airways inflammatory diseases
M Maniscalco
Department of Respiratory Medicine, University Federico II of Naples, Largo delle Mimose, 1, 80131 Naples, Italy
Inflamm Res 56:58-69. 2007
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- Validation study of nasal nitric oxide measurements using a hand-held electrochemical analyser
M Maniscalco
Section of Respiratory Medicine, Hospital S Maria della Pietà Casoria Naples, Italy
Eur J Clin Invest 38:197-200. 2008
..The application of this hand-held analyser in nasal NO analysis was tested and compared to the gold standard represented by a chemiluminescence analyser...
- Evaluation of a transcutaneous carbon dioxide monitor in severe obesity
Mauro Maniscalco
Section of Respiratory Medicine, Hospital S Maria della Pietà, CAP 80026, Casoria, Naples, Italy
Intensive Care Med 34:1340-4. 2008
..To determine the reliability of estimating arterial CO(2) pressure (PaCO(2)) using a recently introduced transcutaneous CO(2) pressure (PtcCO(2)) monitor in severe obese patients...
- Hand-held nitric oxide sensor NIOX MINO® for the monitoring of respiratory disorders
Mauro Maniscalco
Section of Respiratory Diseases, Hospital S Maria della Pietà of Casoria, Naples, Italy
Expert Rev Respir Med 4:715-21. 2010
..More recently, a new hand-held electrochemical sensor NIOX MINO(®) has been developed. Here, we will review the use of the NIOX MINO for the study of respiratory disorders...
- Increase in exhaled nitric oxide in shoe and leather workers at the end of the work-shift
Mauro Maniscalco
Department of Pharmacology and Physiology, Karolinska Institute Stockholm, Stockholm, Sweden
Occup Med (Lond) 54:404-7. 2004
..The objective of this study was to evaluate exhaled NO levels in synthetic leather workers exposed to organic solvents toluene, xylene and methylethyl ketone...
- Humming-induced release of nasal nitric oxide for assessment of sinus obstruction in allergic rhinitis: pilot study
M Maniscalco
Karolinska Institutet, Stockholm, Sweden
Eur J Clin Invest 34:555-60. 2004
..Humming greatly increases nasal nitric oxide (NO) in healthy people by causing a rapid washout of NO from the sinuses. This increase is abolished in patients with complete sinus ostial obstruction...
- Inhaled ultrasonically nebulized distilled water decreases exhaled nitric oxide in asthma
M Maniscalco
Department of Respiratory Medicine, A O Monaldi, University Federico II of Naples, Naples, Italy
Lung 180:319-26. 2002
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- Nitric oxide attenuates platelet-activating factor induced nasal airway plasma extravasation in healthy subjects
M Maniscalco
Pulmonary and Airway Vascular Unit, Department of Respiratory Medicine AO Monaldi, University Federico II, Naples, Italy
Eur J Clin Invest 32:858-61. 2002
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- Orthodeoxia without platypnea from interatrial defect associated with persistent left superior vena cava in the absence of pulmonary hypertension
Mauro Maniscalco
Pulmonary Vascular and Airway Unit, A O Monaldi, University Federico II of Naples, Italy
Respiration 70:207-10. 2003
..Orthodeoxia and platypnea could occur as separate disease manifestations, the latter probably being a rarer acute event, whereas orthodeoxia was underestimated and potentially earlier screenable...
- Nasal nitric oxide measurements before and after repeated humming maneuvers
M Maniscalco
Karolinska Institute, Stockholm, Sweden
Eur J Clin Invest 33:1090-4. 2003
..This is most likely owing to a rapid washout of sinus NO caused by the oscillating sound waves. During repeated humming manoeuvres nasal NO gradually decreases, likely because NO accumulated in the sinuses is washed out...
- Exhaled nitric oxide after inhalation of isotonic and hypotonic solutions in healthy subjects
M Maniscalco
Department of Respiratory Medicine, University Federico II A O Monaldi, Naples, Italy
Clin Sci (Lond) 101:645-50. 2001
..The UNDW-induced decrease in eNO is not enhanced by pretreatment with the NO synthase inhibitor L-NAME, suggesting that inhaled solutions may interfere with the airway NO pathway in humans...
- Assessment of nasal and sinus nitric oxide output using single-breath humming exhalations
M Maniscalco
Dept of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden
Eur Respir J 22:323-9. 2003
..Combined nasal nitric oxide measurement with and without humming could be of use to estimate sinus ventilation and to better separate nasal mucosal nitric oxide output from sinus nitric oxide in health and disease...
- Metabonomic analysis of exhaled breath condensate in adults by nuclear magnetic resonance spectroscopy
G De Laurentiis
Dept of Respiratory Medicine, Azienda Ospedaliera Monaldi, University of Naples Federico II, 80131 Naples, Italy
Eur Respir J 32:1175-83. 2008
..Moreover, metabonomics of exhaled breath condensate in adults can discriminate potential perturbations induced by pre-analytical variables...
- Exhaled nitric oxide as a marker of adverse respiratory health effect in environmental disease
M Sofia
UOS Diagnostica Fisiopatologica Respiratoria, Dipartimento di Tisiologia e Pneumologia, A O Monaldi, Universita Federico II Napoli, and Direzione Sanitaria A O Monadi, Napoli, Italy
Monaldi Arch Chest Dis 57:182-7. 2002
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- Effect of nitric oxide inhibition on nasal airway resistance after nasal allergen challenge in allergic rhinitis
M Maniscalco
University Federico II, Naples, Italy
Eur J Clin Invest 31:462-6. 2001
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- CD8+ T-cell alveolitis in familial pulmonary alveolar microlithiasis
G De Laurentiis
Dept of Respiratory Medicine, AO Monaldi, Second University of Naples, Naples, Italy
Eur Respir J 30:165-71. 2007
..The relationship between this immune dysregulation and genetic background in pulmonary alveolar microlithiasis warrants further investigation...
- Abnormalities of renal endothelin during acute exacerbation in chronic obstructive pulmonary disease
M Sofia
Dept of Respiratory Medicine, Pulmonary Vascular and Airway Unit, University Federico II, 80131 Naples, Italy
Pulm Pharmacol Ther 14:321-7. 2001
..ET might contribute to the renal response to hypoxaemia and hypercapnia in COPD...
- Effect of bariatric surgery on the six-minute walk test in severe uncomplicated obesity
Mauro Maniscalco
Department of Respiratory Medicine, Hospital S Maria della Pietà Casoria, Naples, Italy
Obes Surg 16:836-41. 2006
..The aim of this study was to determine whether weight reduction induced by laparoscopic adjustable gastric banding (LAGB) improves the functional capacity in the severely obese on the 6mWT...
- Exhaled nitric oxide monitoring in COPD using a portable analyzer
Guglielmo de Laurentiis
Department of Respiratory Diseases, University Federico II, Naples, Italy Department of Pulmonary Diseases, Second University of Naples, Italy
Pulm Pharmacol Ther 21:689-93. 2008
..A very recent statement has suggested FeNO as potential outcome in chronic obstructive pulmonary disease (COPD). Recently, a new hand-held FeNO analyzer (NIOX MINO) has been developed...
- Nasal nitric oxide assessment in primary ciliary dyskinesia using aspiration, exhalation, and humming
Francesca Santamaria
Department of Pediatrics, Federico II University, Naples, Italy
Med Sci Monit 14:CR80-85. 2008
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- Transient decrease of exhaled nitric oxide after acute exposure to passive smoke in healthy subjects
Mauro Maniscalco
Department of Respiratory Medicine, AO Monaldi University Federico II, Naples, Italy
Arch Environ Health 57:437-40. 2002
..Exposure to environmental tobacco smoke transiently--but consistently--decreased eNO concentration in healthy, nonsmoking subjects, suggesting that second-hand smoke can directly affect NO in the airway environment...
- Correlation of transabdominal sonographic and cystoscopic findings in the diagnosis of focal abnormalities of the urinary bladder wall: a prospective study
Giampiero Francica
Diagnostic and Interventional Ultrasound Service, Presidio Ospedaliero Camilliani Santa Maria Della Pietà, Casoria, Italy
J Ultrasound Med 27:887-94. 2008
..The aim of this study was to prospectively assess the diagnostic capabilities of transabdominal sonography performed with newer sonography machines for showing focal bladder wall abnormalities (FBWAs) detected on cystoscopy...
- [Inhibition of nasal nitric oxide in patients with allergic rhinitis]
Mauro Maniscalco
Ann Ital Med Int 17:62. 2002
- Endothelin-1 induces proliferation of human lung fibroblasts and IL-11 secretion through an ET(A) receptor-dependent activation of MAP kinases
Luca Gallelli
Department of Experimental and Clinical Medicine, University Magna Graecia of Catanzaro, Catanzaro, Italy
J Cell Biochem 96:858-68. 2005
..Therefore, such results suggest that in human lung fibroblasts ET-1 exerts a profibrogenic action via an ET(A) receptor-dependent, MAPK-mediated induction of IL-11 release and cell proliferation...
- Passive smoke and exhaled nitric oxide
Mauro Maniscalco
Am J Respir Crit Care Med 165:1188; author reply 1188. 2002
- Nasal nitric oxide in experimental rhinovirus infection
Mauro Maniscalco
J Allergy Clin Immunol 115:207; author reply 207-8. 2005
- Humming, nitric oxide, and paranasal sinus obstruction
Jon O Lundberg
JAMA 289:302-3. 2003
