Alassane Dicko

Summary

Affiliation: University of Bamako
Country: Mali

Publications

  1. pmc The implementation of malaria intermittent preventive trialtreatment with sulphadoxine-pyrimethamine in infants reduced all-cause mortality in the district of Kolokani, Mali: results from a cluster randomized control
    Alassane Dicko
    Malaria Research and Training Center, Faculty of Medicine Pharmacy and Dentistry, University of Bamako, PO Box 1805, Bamako, Mali
    Malar J 11:73. 2012
  2. pmc Modelling malaria incidence with environmental dependency in a locality of Sudanese savannah area, Mali
    Jean Gaudart
    Biostatistics Research Unit, Laboratory of Education and Research in Medical Information Processing LERTIM, EA 3283 Aix Marseille University, Faculty of Medicine, Marseille Cedex 5, France
    Malar J 8:61. 2009
  3. pmc Space-time clustering of childhood malaria at the household level: a dynamic cohort in a Mali village
    Jean Gaudart
    Medical Statistics and Informatics Research Team, LIF UMR 6166 CNRS Aix Marseille University, Faculty of Medicine, 27 Bd Jean Moulin 13385 Marseille Cedex 05, France
    BMC Public Health 6:286. 2006
  4. pmc Impact of intermittent preventive treatment with sulphadoxine-pyrimethamine targeting the transmission season on the incidence of clinical malaria in children in Mali
    Alassane Dicko
    Malaria Research and Training Center, Departments of Epidemiology of Parasitic Diseases, Faculty of Medicine Pharmacy and Dentistry, University of Bamako, P O Box 1805, Bamako, Mali
    Malar J 7:123. 2008
  5. ncbi request reprint Year-to-year variation in the age-specific incidence of clinical malaria in two potential vaccine testing sites in Mali with different levels of malaria transmission intensity
    Alassane Dicko
    Malaria Research and Training Center, Department of Epidemiology of Parasitic Diseases, Faculty of Medicine, Pharmacy and Odonto Stomatology, University of Bamako, Bamako, Mali
    Am J Trop Med Hyg 77:1028-33. 2007
  6. pmc Molecular markers of resistance to sulphadoxine-pyrimethamine one year after implementation of intermittent preventive treatment of malaria in infants in Mali
    Alassane Dicko
    Malaria Research and Training Center, Department of Epidemiology of Parasitic Diseases, Faculty of Medicine Pharmacy and Dentistry, University of Bamako, PO Box 1805 Bamako, Mali
    Malar J 9:9. 2010
  7. ncbi request reprint Season, fever prevalence and pyrogenic threshold for malaria disease definition in an endemic area of Mali
    Alassane Dicko
    Malaria Research and Training Center, Department of Epidemiology of Parasitic Diseases, Faculty of Medicine, Pharmacy and Odonto Stomatology, University of Bamako, Bamako, Mali
    Trop Med Int Health 10:550-6. 2005
  8. pmc Increase in EPI vaccines coverage after implementation of intermittent preventive treatment of malaria in infant with Sulfadoxine -pyrimethamine in the district of Kolokani, Mali: results from a cluster randomized control trial
    Alassane Dicko
    Malaria Research and Training Center, Department of Epidemiology of Parasitic Diseases, University of Bamako, Mali
    BMC Public Health 11:573. 2011
  9. pmc Primary vaccination with the 10-valent pneumococcal non-typeable Haemophilus influenzae protein D conjugate vaccine (PHiD-CV) in infants in Mali and Nigeria: a randomized controlled trial
    Alassane Dicko
    Malaria Research and Training Center, Faculty of Medicine, Pharmacy and Dentistry, University of Bamako, P, O, Box 1805, Bamako, Mali
    BMC Public Health 11:882. 2011
  10. pmc Malaria morbidity in children in the year after they had received intermittent preventive treatment of malaria in Mali: a randomized control trial
    Alassane Dicko
    Malaria Research and Training Centre, Faculty of Medicine Pharmacy and Dentistry, University of Bamako, Bamako, Mali
    PLoS ONE 6:e23390. 2011

Detail Information

Publications35

  1. pmc The implementation of malaria intermittent preventive trialtreatment with sulphadoxine-pyrimethamine in infants reduced all-cause mortality in the district of Kolokani, Mali: results from a cluster randomized control
    Alassane Dicko
    Malaria Research and Training Center, Faculty of Medicine Pharmacy and Dentistry, University of Bamako, PO Box 1805, Bamako, Mali
    Malar J 11:73. 2012
    ..However, there was no published study on the impact of the strategy on mortality. The present study assessed the impact of the implementation of IPTi-SP in health services in Mali on all-cause mortality...
  2. pmc Modelling malaria incidence with environmental dependency in a locality of Sudanese savannah area, Mali
    Jean Gaudart
    Biostatistics Research Unit, Laboratory of Education and Research in Medical Information Processing LERTIM, EA 3283 Aix Marseille University, Faculty of Medicine, Marseille Cedex 5, France
    Malar J 8:61. 2009
    ..Remote sensing data on environment were incorporated into a temporal model of the transmission, to forecast the evolution of malaria epidemiology, in a locality of Sudanese savannah area...
  3. pmc Space-time clustering of childhood malaria at the household level: a dynamic cohort in a Mali village
    Jean Gaudart
    Medical Statistics and Informatics Research Team, LIF UMR 6166 CNRS Aix Marseille University, Faculty of Medicine, 27 Bd Jean Moulin 13385 Marseille Cedex 05, France
    BMC Public Health 6:286. 2006
    ..The aim of this study was to identify, spatially and temporally, high-risk zones of malaria, at the household level (resolution of 1 to 3 m)...
  4. pmc Impact of intermittent preventive treatment with sulphadoxine-pyrimethamine targeting the transmission season on the incidence of clinical malaria in children in Mali
    Alassane Dicko
    Malaria Research and Training Center, Departments of Epidemiology of Parasitic Diseases, Faculty of Medicine Pharmacy and Dentistry, University of Bamako, P O Box 1805, Bamako, Mali
    Malar J 7:123. 2008
    ..However in most areas malaria morbidity and mortality remain high in older children...
  5. ncbi request reprint Year-to-year variation in the age-specific incidence of clinical malaria in two potential vaccine testing sites in Mali with different levels of malaria transmission intensity
    Alassane Dicko
    Malaria Research and Training Center, Department of Epidemiology of Parasitic Diseases, Faculty of Medicine, Pharmacy and Odonto Stomatology, University of Bamako, Bamako, Mali
    Am J Trop Med Hyg 77:1028-33. 2007
    ..Our results suggest that, although the age distribution of clinical malaria depends on transmission intensity, the total burden of disease may be similar or higher in settings of low transmission...
  6. pmc Molecular markers of resistance to sulphadoxine-pyrimethamine one year after implementation of intermittent preventive treatment of malaria in infants in Mali
    Alassane Dicko
    Malaria Research and Training Center, Department of Epidemiology of Parasitic Diseases, Faculty of Medicine Pharmacy and Dentistry, University of Bamako, PO Box 1805 Bamako, Mali
    Malar J 9:9. 2010
    ..However, there is a fear that IPTi may result in a rapid increase of parasite resistance to SP...
  7. ncbi request reprint Season, fever prevalence and pyrogenic threshold for malaria disease definition in an endemic area of Mali
    Alassane Dicko
    Malaria Research and Training Center, Department of Epidemiology of Parasitic Diseases, Faculty of Medicine, Pharmacy and Odonto Stomatology, University of Bamako, Bamako, Mali
    Trop Med Int Health 10:550-6. 2005
    ..Modelling malaria parasitaemia as function of fever has been proposed as best alternative to estimate the attributable fraction of malaria fever and the sensitivity and specificity of different case definitions of malaria disease...
  8. pmc Increase in EPI vaccines coverage after implementation of intermittent preventive treatment of malaria in infant with Sulfadoxine -pyrimethamine in the district of Kolokani, Mali: results from a cluster randomized control trial
    Alassane Dicko
    Malaria Research and Training Center, Department of Epidemiology of Parasitic Diseases, University of Bamako, Mali
    BMC Public Health 11:573. 2011
    ..However IPTi may also increase the adherence of the community to EPI services and improve EPI coverage, once the benefice of strategy is perceived...
  9. pmc Primary vaccination with the 10-valent pneumococcal non-typeable Haemophilus influenzae protein D conjugate vaccine (PHiD-CV) in infants in Mali and Nigeria: a randomized controlled trial
    Alassane Dicko
    Malaria Research and Training Center, Faculty of Medicine, Pharmacy and Dentistry, University of Bamako, P, O, Box 1805, Bamako, Mali
    BMC Public Health 11:882. 2011
    ..The immunogenicity, safety and reactogenicity of 3-dose primary vaccination with the 10-valent pneumococcal non-typeable Haemophilus influenzae protein D conjugate vaccine (PHiD-CV) were evaluated in infants in Mali and Nigeria...
  10. pmc Malaria morbidity in children in the year after they had received intermittent preventive treatment of malaria in Mali: a randomized control trial
    Alassane Dicko
    Malaria Research and Training Centre, Faculty of Medicine Pharmacy and Dentistry, University of Bamako, Bamako, Mali
    PLoS ONE 6:e23390. 2011
    ..Here we report the results of a follow-on study undertaken to establish whether children who had received IPTc would be at increased risk of malaria during the subsequent malaria transmission season...
  11. pmc Efficacy of chloroquine, amodiaquine and sulphadoxine-pyrimethamine for the treatment of uncomplicated falciparum malaria: revisiting molecular markers in an area of emerging AQ and SP resistance in Mali
    Mamadou Tekete
    Department of Epidemiology of Parasitic Diseases, Faculty of Medicine, Malaria Research and Training Center, Bamako, Mali
    Malar J 8:34. 2009
    ..To update the National Malaria Control Programme of Mali on the efficacy of chloroquine, amodiaquine and sulphadoxine-pyrimethamine in the treatment of uncomplicated falciparum malaria...
  12. pmc A randomized and controlled Phase 1 study of the safety and immunogenicity of the AMA1-C1/Alhydrogel + CPG 7909 vaccine for Plasmodium falciparum malaria in semi-immune Malian adults
    Issaka Sagara
    Malaria Research and Training Center, Faculty of Medicine Pharmacy and Dentistry, BP 1805, Bamako, University of Bamako, Mali
    Vaccine 27:7292-8. 2009
    ..05). This is the first use of the novel adjuvant CPG 7909 in a malaria-exposed population...
  13. pmc Lack of allele-specific efficacy of a bivalent AMA1 malaria vaccine
    Amed Ouattara
    Malaria Research and Training Center, Department of Epidemiology of Parasitic Diseases, Faculty of Medicine, Pharmacy and Dentistry, Bamako, Mali
    Malar J 9:175. 2010
    ....
  14. pmc A randomized controlled phase 2 trial of the blood stage AMA1-C1/Alhydrogel malaria vaccine in children in Mali
    Issaka Sagara
    Malaria Research and Training Center, Faculty of Medicine Pharmacy and Dentistry BP 1805 Bamako, University of Bamako, Mali, Malaysia
    Vaccine 27:3090-8. 2009
    ..5 g/dL, in the direction of lower hemoglobin in the children who received AMA1-C1, although these differences were not significant after correction for multiple tests. These differences were not seen in the second year of transmission...
  15. pmc Safety and immunogenicity of an AMA-1 malaria vaccine in Malian adults: results of a phase 1 randomized controlled trial
    Mahamadou A Thera
    Malaria Research and Training Center, University of Bamako, Bamako, Mali
    PLoS ONE 3:e1465. 2008
    ..The objective was to evaluate the safety, reactogenicity and immunogenicity of the AMA-1-based blood-stage malaria vaccine FMP2.1/AS02A in adults exposed to seasonal malaria...
  16. ncbi request reprint The etiology of severe anemia in a village and a periurban area in Mali
    Alassane Dicko
    Malaria Research and Training Center, Department of Epidemiology of Parasitic Diseases, Faculty of Medicine, Pharmacy and Odonto Stomatology, University of Bamako, PO Box 1805, Bamako, Mali
    Blood 104:1198-200. 2004
    ..2 years of age. Raising the baseline hemoglobin level and lowering peak parasitemia in infants and young children may reduce the incidence of severe anemia resulting from malarial infection...
  17. ncbi request reprint Efficacy, safety, and selection of molecular markers of drug resistance by two ACTs in Mali
    Abdoulaye A Djimde
    Malaria Research and Training Center, Department of Epidemiology of Parasitic Diseases, Faculty of Medicine, Pharmacy and Odonto Stomatology, University of Bamako, Bamako, Mali
    Am J Trop Med Hyg 78:455-61. 2008
    ..The ACTs were efficacious and safe, but the selection of markers for resistance to the partner drugs raises concerns over their lifespan in areas of intense malaria transmission...
  18. pmc Repeated artemisinin-based combination therapies in a malaria hyperendemic area of Mali: efficacy, safety, and public health impact
    Issaka Sagara
    Malaria Research and Training Center, Department of Epidemiology of Parasitic Diseases, Faculty of Medicine, Pharmacy and Odonto Stomatology, University of Bamako, Bamako, Mali
    Am J Trop Med Hyg 87:50-6. 2012
    ..002) and RR = 0.80 (P = 0.001), respectively. The treatment efficacy was similar and above 95% in all arms. Although all drugs were highly efficacious and well tolerated, AS+AQ and AS+SP were associated with less episodes of malaria...
  19. ncbi request reprint A high malaria reinfection rate in children and young adults living under a low entomological inoculation rate in a periurban area of Bamako, Mali
    Issaka Sagara
    Malaria Research and Training Center, Département d épidémiologie des affections parasitaires, Faculte de Medicine, de Pharmacie et d Odonto Stomatologie, Université du Mali, Bamako
    Am J Trop Med Hyg 66:310-3. 2002
    ..5 infected bites/person/month. The finding that reinfection rates were high despite low EIRs suggests that a low EIR may be sufficient to support small sample size vaccine efficacy trials in mesoendemic areas...
  20. ncbi request reprint A randomized trial of artesunate-mefloquine versus artemether-lumefantrine for treatment of uncomplicated Plasmodium falciparum malaria in Mali
    Issaka Sagara
    Malaria Research and Training Center, Department of Epidemiology of Parasitic Diseases, Faculty of Medicine, Pharmacy and Odonto Stomatology, University of Bamako, Bamako, Mali
    Am J Trop Med Hyg 79:655-61. 2008
    ..04% versus 96.93%). Artesunate-mefloquine is well-tolerated and is as effective as artemether-lumefantrine for the treatment of P. falciparum malaria. Artesunate-mefloquine also prevented more new infections...
  21. ncbi request reprint Impact of preseason treatment on incidence of falciparum malaria and parasite density at a site for testing malaria vaccines in Bandiagara, Mali
    Drissa Coulibaly
    Malaria Research and Training Center, Faculty of Medicine, Pharmacy and Dentistry, University of Mali, Bamako, Mali, West Africa
    Am J Trop Med Hyg 67:604-10. 2002
    ....
  22. pmc Efficacy and safety of a fixed dose artesunate-sulphamethoxypyrazine-pyrimethamine compared to artemether-lumefantrine for the treatment of uncomplicated falciparum malaria across Africa: a randomized multi-centre trial
    Issaka Sagara
    Malaria Research and Training Center, Department of Epidemiology of Parasitic Diseases, Faculty of Medicine, Pharmacy and Odonto Stomatology, University of Bamako, Bamako, Mali
    Malar J 8:63. 2009
    ..Ease of administration of anti-malarial treatments with shorter courses and fewer tablets may be key determinant of compliance...
  23. ncbi request reprint Malaria incidence in relation to rice cultivation in the irrigated Sahel of Mali
    Mahamadou Soumana Sissoko
    Département d épidémiologie des affections parasitaires, Faculte de Medecine, de Pharmacie et d Odonto Stomatologie, BP 1805, Bamako, Mali
    Acta Trop 89:161-70. 2004
    ..Rice cultivation in the semi-arid sub-Saharan environment altered the transmission pattern from seasonal to perennial, but reduced annual incidence more than two-fold...
  24. pmc Phase 1 study of a combination AMA1 blood stage malaria vaccine in Malian children
    Alassane Dicko
    Malaria Research and Training Center, Department of Epidemiology of Parasitic Diseases, Faculty of Medicine, Pharmacy and Dentistry, University of Bamako, Bamako, Mali
    PLoS ONE 3:e1563. 2008
    ..The aim of this study was to assess the safety and immunogenicity of this vaccine in young children in a malaria endemic area...
  25. pmc Serum antibody levels to glycosylphosphatidylinositols in specimens derived from matched Malian children with severe or uncomplicated Plasmodium falciparum malaria and healthy controls
    Yacouba Cissoko
    Bandiagara Malaria Project, Department of Epidemiology of Parasitic Diseases, Faculty of Medicine, Pharmacy and Dentistry, Malaria Research and Training Center, University of Bamako, Bamako, Mali
    Am J Trop Med Hyg 75:199-204. 2006
    ..A direct correlation between age and parasitemia and IgG antibodies to GPI was observed. In summary, higher levels of IgM and IgG antibodies to GPI in young children were associated with disease severity and were short-lived...
  26. pmc Impact of a Plasmodium falciparum AMA1 vaccine on antibody responses in adult Malians
    Alassane Dicko
    Malaria Research and Training Center, Department of Hematology, University of Bamako, Bamako, Mali
    PLoS ONE 2:e1045. 2007
    ..After a peak 14 days following the second vaccination, antibody levels decreased to baseline levels one year later at the time of the third vaccination that induced little or no increase in antibody levels...
  27. ncbi request reprint A randomized trial of artesunate-sulfamethoxypyrazine-pyrimethamine versus artemether-lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria in Mali
    Issaka Sagara
    Malaria Research and Training Center, Department of Epidemiology of Parasitic Diseases, Faculty of Medicine, Pharmacy, and Odonto Stomatology, University of Bamako, Bamako, Mali
    Am J Trop Med Hyg 75:630-6. 2006
    ..0%, respectively (P = 0.08). No serious adverse events occurred. Artesunate-sulfamethoxypyrazine-pyrimethamine is well-tolerated and effective against P. falciparum malaria. It showed an additional benefit of preventing new infections...
  28. ncbi request reprint A comparison of anemia in hemoglobin C and normal hemoglobin A children with Plasmodium falciparum malaria
    Dapa A Diallo
    faculté de médecine de pharmacie et d odontostomatologie, University of Bamako, Bamako, Mali
    Acta Trop 90:295-9. 2004
    ..By this measure, HbC, a malaria-protective polymorphism with few deleterious consequences, does not appear to be associated with more frequent anemia than normal HbA in episodes of uncomplicated P. falciparum malaria...
  29. ncbi request reprint Clearance of drug-resistant parasites as a model for protective immunity in Plasmodium falciparum malaria
    Abdoulaye A Djimde
    Bandiagara Malaria Project, Malaria Research and Training Center, Department of Epidemiology of Parasitic Diseases, Faculty of Medicine, Pharmacy and Dentistry, University of Bamako, Bamako, Mali
    Am J Trop Med Hyg 69:558-63. 2003
    ..Age-adjusted comparison of subjects able to clear resistant parasites and those unable to do so provides a new phenotype for identifying host immune and genetic factors responsible for protective immunity against malaria...
  30. pmc Impact of trimethoprim-sulfamethoxazole prophylaxis on falciparum malaria infection and disease
    Mahamadou A Thera
    Bandiagara Malaria Project, Malaria Research and Training Center, University of Bamako, Mali
    J Infect Dis 192:1823-9. 2005
    ..CONCLUSIONS. In this setting of low antifolate resistance, TS was highly effective in preventing falciparum malaria infection and disease and did not appear to select for SP-resistant parasites...
  31. pmc Plasmodium falciparum clearance with artemisinin-based combination therapy (ACT) in patients with glucose-6-phosphate dehydrogenase deficiency in Mali
    Abdoulaye K Kone
    Malaria Research and Training Center, Faculty of Medicine, Pharmacy and Odonto Stomatology, University of Bamako, P, O, Box 1805 Bamako, Mali
    Malar J 9:332. 2010
    ..The impact of G6PD deficiency on parasite clearance with ACT treatment was compared between G6PD-deficient patients and G6PD-normal group...
  32. ncbi request reprint Risk factors for malaria infection and anemia for pregnant women in the Sahel area of Bandiagara, Mali
    Alassane Dicko
    Department of Epidemiology of Parasitic Diseases, Faculty of Medicine, Pharmacy and Odonto Stomatology, Malaria Research and Training Center, Bamako, Mali
    Acta Trop 89:17-23. 2003
    ..Thus, control measures against malaria infection should target younger rural women in their first trimester of pregnancy...
  33. pmc The TLR9 agonist CpG fails to enhance the acquisition of Plasmodium falciparum-specific memory B cells in semi-immune adults in Mali
    Boubacar Traore
    Malaria Research and Training Center, Faculty of Medicine, Pharmacy and Odonto Stomatology, Department of Epidemiology of Parasitic Diseases BP 1805 Bamako, Mali
    Vaccine 27:7299-303. 2009
    ..Understanding the molecular basis of this apparent refractoriness to TLR9 agonist will be of significant interest in vaccine design...
  34. pmc Intermittent preventive treatment of malaria provides substantial protection against malaria in children already protected by an insecticide-treated bednet in Mali: a randomised, double-blind, placebo-controlled trial
    Alassane Dicko
    Malaria Research and Training Centre, Faculty of Medicine Pharmacy and Dentistry, University of Bamako, Bamako, Mali
    PLoS Med 8:e1000407. 2011
    ..However, these studies were conducted in communities with low coverage with insecticide-treated nets (ITNs). Whether IPTc provides additional protection to children sleeping under an ITN has not been established...
  35. ncbi request reprint Responses to comments by Ishag Adam and Mustafa Idriss El Bechir on our paper "Risk factors for malaria infection and anemia for pregnant women in the Sahel area of Bandiagara, Mali" published in Acta Tropica 89 (1) 17-23
    Alassane Dicko
    Malaria Research and Training Center, Faculty of Medicine, Pharmacy and Odonto Stomatology, Department of Epidemiology of Parasitic Diseases, Bamako, Mali
    Acta Trop 96:62-3. 2005