Time to 'get real': preliminary insights into the long-term management of schizophreniaGin Malhi
Discipline of Psychiatry, University of Sydney, NSW, Australia
Australas Psychiatry 18:115-9. 2010
..A brief file and medication chart review was undertaken to examine the 'real world' treatment of schizophrenia, with a particular focus on long-term treatment strategies that extend beyond existing evidence-based guidelines...
Neuropsychological deficits and functional impairment in bipolar depression, hypomania and euthymiaGin S Malhi
Academic Discipline of Psychological Medicine, Northern Clinical School, University of Sydney, Sydney, NSW, Australia
Bipolar Disord 9:114-25. 2007
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- Familiarity breeds respect: attitudes of medical students towards psychiatry following a clinical attachment
Lisa Lampe
Discipline of Psychiatry, University of Sydney, NSW, Australia
Australas Psychiatry 18:348-53. 2010
..The aim of this paper was to examine the influence of a clinical attachment in psychiatry on medical students' attitudes to psychiatry as a specialty and potential career...
- Great expectations: factors influencing patient expectations and doctors recommendations at a Mood Disorders Unit
Kay Wilhelm
School of Psychiatry, University of New South Wales and Mood Disorders Unit, Black Dog Institute, Sydney, Australia
J Affect Disord 88:187-92. 2005
..We examined the factors influencing treatment expectations and psychiatrists' treatment recommendations for patients referred to a mood disorders unit with identified episodes of major depression...
- Up close and personal: medical students prefer face-to-face teaching in psychiatry
Lisa Lampe
Discipline of Psychiatry, University of Sydney, NSW, Australia
Australas Psychiatry 18:354-60. 2010
..The aim of this paper was to determine the teaching activities most valued by medical students in the psychiatry rotation and to examine whether this varies with age, gender or stage of training...
- Medical students' attitudes towards a career in psychiatry before and after viewing a promotional DVD
Tasha Robertson
University of Sydney Graduate Medical Program, University of Sydney, Sydney, NSW, Australia
Australas Psychiatry 17:311-7. 2009
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- Self-reported side effects in children and adolescents taking risperidone
Simon Byrne
Northern Sydney Central Coast Health, NSW, Australia
Australas Psychiatry 18:42-5. 2010
..We aimed to describe medication side effects in a cross-section of young people taking low-dose risperidone, using a self-report measure...
- Diagnostic processes in mental health: GPs and psychiatrists reading from the same book but on a different page
Lisa Lampe
Discipline of Psychiatry, Sydney Medical School, University of Sydney, Sydney, NSW, Australia
Australas Psychiatry 20:374-8. 2012
..To explore the clinical reasoning processes underpinning diagnostic and management decision-making in treating patients presenting with psychological distress in general practice...
- To medicate or not to medicate, when diagnosis is in question: decision-making in first episode psychosis
Gin Malhi
Department of Academic Psychiatry, CADE Clinic, Royal North Shore Hospital, NSW, Australia
Australas Psychiatry 18:230-7. 2010
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- Memory and executive functioning in obsessive-compulsive disorder: a selective review
Amanda Olley
School of Psychiatry, University of New South Wales, Sydney, Australia
J Affect Disord 104:15-23. 2007
..This paper reviews the main neuropsychological findings in memory and executive functioning in this disorder, and examines a number of challenges facing this area of research...
- Depression, financial problems and other reasons for suspending medical studies, and requested support services: findings from a qualitative study
Nerissa Soh
Child and Adolescent Mental Health Services, Northern Sydney Local Health District, Sydney, NSW, Australia
Australas Psychiatry 20:518-23. 2012
..This study aimed to qualitatively explore medical students' reasons for suspending, or thinking of suspending, their studies and the types of support services they request...
- Side effects of second-generation antipsychotics: the experiences, views and monitoring practices of Australian child psychiatrists
Garry Walter
Discipline of Psychological Medicine, University of Sydney, Australia
Australas Psychiatry 16:253-62. 2008
..The aim of this study was to ascertain the experiences, views and monitoring practices of Australian child psychiatrists regarding the metabolic and other side effects of second-generation antipsychotics (SGAs)...
- Clozapine and cardiometabolic health in chronic schizophrenia: correlations and consequences in a clinical context
Gin Malhi
Discipline of Psychological Medicine, University of Sydney, Australia
Australas Psychiatry 18:32-41. 2010
..The aim of this study was to identify the prevalence of metabolic syndrome and its putative precursors in a naturalistic study of non-acute inpatients at a psychiatric hospital...
- Self-harming in depressed patients: pattern analysis
G Parker
School of Psychiatry, University of New South Wales, Sydney, Australia
Aust N Z J Psychiatry 39:899-906. 2005
..As deliberate self-harm (DSH) is a common concomitant of depressive disorders, we undertook a study examining the relevance of possible determinants and correlates of DSH...
- Transcranial magnetic stimulation for the deficit syndrome of schizophrenia: a pilot investigation
Perminder Sachdev
School of Psychiatry, University of New South Wales, Sydney, Australia
Psychiatry Clin Neurosci 59:354-7. 2005
..Repetitive transcranial magnetic stimulation as a treatment of the deficit syndrome of schizophrenia is feasible, safe and may be beneficial. A systematic study in randomized control trials would be appropriate...
- Neural correlates of emotional face processing in bipolar disorder: an event-related potential study
Racheal Degabriele
School of Psychiatry, The University of New South Wales, Sydney, Australia
J Affect Disord 133:212-20. 2011
..The aim of our study was to explore these processes as indexed by the face-specific P100 and N170 ERP components in a BD cohort...
- Female medical students: who might make the cut?
Carissa Coulston
Discipline of Psychiatry, Sydney Medical School, University of Sydney, Sydney, NSW, Australia
Psychiatry Res 200:457-63. 2012
..In our sample, the females interested in surgery retained an overall similar personality profile to those less interested, with only few differences...
- Comment: clinical practice guidelines--guiding or goading?
Gin Malhi
CADE Clinic, Northern Clinical School, University of Sydney, Sydney, NSW, Australia
Australas Psychiatry 16:5-7. 2008
- Age and gender in the phenomenology of depression
Henry Brodaty
Academic Dept for Old Age Psychiatry, Mood Disorders Unit, Black Dog Institute, Prince of Wales Hospital, Sydney, Australia
Am J Geriatr Psychiatry 13:589-96. 2005
..Authors investigated the effects of current age, age at onset, and gender on the phenomenology of depression...
- Executive functioning and theory of mind in euthymic bipolar disorder
Amanda L Olley
School of Psychiatry, Black Dog Institute, University of New South Wales, Sydney, NSW, Australia
Bipolar Disord 7:43-52. 2005
..This is consistent with other neuropsychological and neuroimaging research that points to a trait deficit in BD. Further investigation is necessary perhaps using more real-world tests...
- The cognitive and neurophysiological basis of emotion dysregulation in bipolar disorder
Melissa J Green
School of Psychiatry, University of New South Wales, Sydney NSW 2031, Australia
J Affect Disord 103:29-42. 2007
..This network is critical for emotion regulation...
- Do cognitive deficits in juvenile bipolar disorder persist into adulthood?
Catherine M Cahill
Academic Discipline of Psychological Medicine, Royal North Shore Hospital, Northern Clinical School, University of Sydney, Australia
J Nerv Ment Dis 195:891-6. 2007
..Precise knowledge about when, how, and why these deficits appear requires future research of prodromal changes in neurocognition in childhood and adolescent bipolar disorder...
- Bipolar disorder: it's all in your mind? The neuropsychological profile of a biological disorder
Gin S Malhi
Black Dog Institute, Prince of Wales Hospital, Sydney, Australia
Can J Psychiatry 49:813-9. 2004
..To compare and contrast the neuropsychological profile of the 3 phases of bipolar disorder (BD) to achieve a better definition of BD and to identify potential state and trait deficits...
An event-related functional MRI study of working memory in euthymic bipolar disorderJim Lagopoulos
Psychological Medicine Northern Clinical School, University of Sydney, Sydney, Australia
J Psychiatry Neurosci 32:174-84. 2007
..In this study, we investigated the encode, delay and response components of WM to identify the neural substrates and respective contributions to the WM deficits found in BD...
- Schizoaffective disorder: diagnostic issues and future recommendations
Gin S Malhi
Northern Clinical School, University of Sydney, Sydney, Australia
Bipolar Disord 10:215-30. 2008
..This paper addresses the controversy regarding the diagnostic validity of schizoaffective disorder (SAD), a diagnosis that is used in both DSM-IV and ICD-10 and one that encroaches on both schizophrenia (SCZ) and bipolar disorder (BD)...
- The empirical redefinition of the psychometric criteria for remission in bipolar disorder
Michael Berk
Barwon Health and The Geelong Clinic, Geelong, Victoria, Australia
J Affect Disord 106:153-8. 2008
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- The rise and fall of mood stabilizers
Gin S Malhi
Aust N Z J Psychiatry 41:779-83. 2007
- The Bipolar Depression Rating Scale (BDRS): its development, validation and utility
Michael Berk
Barwon Health and The Geelong Clinic, Geelong Department of Clinical and Biomedical Sciences, University of Melbourne and ORYGEN Research Centre, Melbourne, Victoria, Australia
Bipolar Disord 9:571-9. 2007
..Both clinically and in research there is a growing need for a new observer-rated scale that is specifically designed to assess bipolar depression...
- A functional magnetic resonance imaging study of emotional Stroop in euthymic bipolar disorder
Jim Lagopoulos
CADE Clinic, Royal North Shore Hospital, The University of Sydney, Sydney, Australia
Neuroreport 18:1583-7. 2007
..This study provides evidence for a disconnection in the transfer of information within frontostriatal networks in bipolar disorder...
- Increased anterior cingulate cortex volume in bipolar I disorder
Ali Javadapour
Neuropsychiatric Institute, Prince of Wales Hospital, Sydney, New South Wales, Australia
Aust N Z J Psychiatry 41:910-6. 2007
..Hence, the present study matched the groups closely across a number of demographic parameters...
- Setting the stage: from prodrome to treatment resistance in bipolar disorder
Michael Berk
Barwon Health and The Geelong Clinic, Geelong, Victoria, Australia
Bipolar Disord 9:671-8. 2007
..At the other end of the spectrum, the model attempts to operationalize treatment resistance. The utility of the model will need to be validated by empirical research...
- Diagnostic guidelines for bipolar disorder: a summary of the International Society for Bipolar Disorders Diagnostic Guidelines Task Force Report
S Nassir Ghaemi
Bipolar Disorder Research Program, Department of Psychiatry, Emory University, Atlanta, GA 30322, USA
Bipolar Disord 10:117-28. 2008
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- Bipolar depression: phenomenological overview and clinical characteristics
Philip B Mitchell
School of Psychiatry, University of New South Wales and Mood Disorders Unit, Black Dog Institute, Prince of Wales Hospital, Sydney, NSW, Australia
Bipolar Disord 6:530-9. 2004
..This paper aims to review the clinical characteristics of bipolar depression, focusing upon its prevalence and phenomenology, related neuropsychological dysfunction, suicidal behaviour, disability and treatment responsiveness...
- Anatomical abnormalities of the anterior cingulate and paracingulate cortex in patients with bipolar I disorder
Alex Fornito
Melbourne Neuropsychiatry Centre, The University of Melbourne, Melbourne, Australia
Psychiatry Res 162:123-32. 2008
..These findings suggest that bipolar disorder is associated with more pronounced changes in the PaC, and that reliance on volumetric measures alone may obscure more subtle differences...
- Repetitive transcranial magnetic stimulation for the treatment of obsessive compulsive disorder: a double-blind controlled investigation
Perminder S Sachdev
School of Psychiatry, University of New South Wales, Australia
Psychol Med 37:1645-9. 2007
..To determine the efficacy and tolerability of repetitive transcranial magnetic stimulation (rTMS) as a treatment for obsessive compulsive disorder (OCD) in a double-blind placebo-controlled study...
- Is a lack of disgust something to fear? A functional magnetic resonance imaging facial emotion recognition study in euthymic bipolar disorder patients
Gin S Malhi
CADE Clinic, Royal North Shore Hospital, University of Sydney, Australia
Bipolar Disord 9:345-57. 2007
..To determine the neural responses invoked in the recognition of facial fear and disgust in euthymic bipolar patients as compared with healthy subjects...
- Comparison of diagnostic guidelines for juvenile bipolar disorder
Catherine Cahill
University of Sydney Discipline of Psychological Medicine, Royal North Shore Hospital, Sydney, Australia
Aust N Z J Psychiatry 41:479-84. 2007
..It is recommended that clinicians and researchers need to develop diagnostic guidelines that have clinical salience and can be used for future research by incorporating key features of those that are currently available...
- The expanding pharmacopoeia for bipolar disorder
Philip B Mitchell
School of Psychiatry, University of New South Wales, Sydney, NSW 2052, Australia
Annu Rev Med 53:173-88. 2002
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- When euthymia is just not good enough: the neuropsychology of bipolar disorder
Amanda Olley
School of Psychiatry, University of New South Wales and Mood Disorders Unit, Black Dog Institute, Prince of Wales Hospital, Sydney, Australia
J Nerv Ment Dis 193:323-30. 2005
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- Treatment of bipolar depression: focus on pharmacologic therapies
Philip B Mitchell
University of New South Wales, School of Psychiatry, Prince of Wales Hospital, Randwick, New South Wales 2031, Australia
Expert Rev Neurother 5:69-78. 2005
..The advent of new pharmacologic and psychologic treatments provides optimism for improved outcomes for this highly disabling condition...
- Anatomical MRI abnormalities in bipolar disorder: do they exist and do they progress?
E Serap Monkul
Department of Psychiatry, Dokuz Eylul University School of Medicine, Izmir, Turkey
Aust N Z J Psychiatry 39:222-6. 2005
..We reviewed the anatomical brain imaging literature in bipolar disorder, in an attempt to determine whether there is evidence to suggest that such abnormalities are progressive...
- 'Bipolar missed states': the diagnosis and clinical salience of bipolar mixed states
Michael Berk
Barwon Health and The Geewong Clinic, Swanston Centre, PO Box 281, Geelong, Victoria 3220, Australia
Aust N Z J Psychiatry 39:215-21. 2005
..To explore diagnostic and treatment issues concerning bipolar mixed states...
- Major advances in bipolar disorder
Philip B Mitchell
School of Psychiatry, University of New South Wales, Prince of Wales Hospital, Randwick, NSW 2031, Australia
Med J Aust 181:207-10. 2004
..Comorbidity with anxiety disorders or substance misuse is common. Advances in genetics, brain imaging and basic pharmacology are starting to provide understanding of the complex causative processes...
- Cognitive generation of affect in hypomania: an fMRI study
Gin S Malhi
School of Psychiatry, University of New South Wales, Sydney, Australia
Bipolar Disord 6:271-85. 2004
..To identify the brain regions associated with the cognitive generation of affect in hypomanic bipolar patients...
- Cognitive generation of affect in bipolar depression: an fMRI study
Gin S Malhi
School of Psychiatry, University of New South Wales, Sydney, Australia
Eur J Neurosci 19:741-54. 2004
..The differential patterns of activation inform us about bipolar depression and have potential diagnostic and therapeutic significance...
- Neural abnormalities during cognitive generation of affect in treatment-resistant depression
Veena Kumari
Section of Cognitive Psychopharmacology, Institute of Psychiatry, King's College, London, UK
Biol Psychiatry 54:777-91. 2003
..The results also corroborate previous observations from resting positron emission tomography studies and further elucidate the association between hypoactive rostral cingulate and nonresponsiveness to treatment in depression...
- Bipolar depression: management options
Gin S Malhi
School of Psychiatry, University of New South Wales, Randwick, Sydney, New South Wales, Australia
CNS Drugs 17:9-25. 2003
..It therefore warrants prompt management once suitably diagnosed, especially as it is associated with a considerable risk of suicide and in the majority of instances is eminently treatable...
- Relationship between self-reported childhood behavioral inhibition and lifetime anxiety disorders in a clinical sample
Gemma L Gladstone
University of New South Wales and Prince of Wales Hospital, Randwick, Australia
Depress Anxiety 22:103-13. 2005
..Findings are discussed in light of the existing risk-factor literature and support the hypothesis that an early inhibited temperament may be a significant precursor to later anxiety, especially social anxiety disorder...
- An emotional Stroop functional MRI study of euthymic bipolar disorder
Gin S Malhi
School of Psychiatry, University of New South Wales, Sydney, Australia
Bipolar Disord 7:58-69. 2005
..To identify the brain regions associated with emotional processing in euthymic bipolar patients...
- Regional gray matter changes in bipolar disorder: a voxel-based morphometric study
Xiaohua Chen
Neuropsychiatric Institute, Euroa Centre, Prince of Wales Hospital, Randwick, New South Wales, Australia
Aust N Z J Psychiatry 41:327-36. 2007
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- Diagnosing bipolar disorder: how can we do it better?
Michael Berk
Department of Clinical and Biomedical Sciences, Barwon Health, University of Melbourne, Geelong, Vic, Australia
Med J Aust 184:459-62. 2006
..There is a risk of over-diagnosis of bipolar disorder among patients who are histrionic, show abnormal illness behaviour and/or have issues of secondary gain...
- A sham-controlled trial of the efficacy and safety of twice-daily rTMS in major depression
Colleen K Loo
School of Psychiatry, University of NSW and Black Dog Institute, Sydney, Australia
Psychol Med 37:341-9. 2007
..Studies of repetitive transcranial magnetic stimulation (rTMS) in depression have mostly involved once-daily treatment, with positive but modest clinical results. This study tested the efficacy and safety of twice-daily rTMS over 2 weeks...
- Emerging drugs for bipolar disorder
Philip B Mitchell
School of Psychiatry, University of New South Wales, Black Dog Institute, Prince of Wales Hospital, Randwick, Sydney, NSW 2031, Australia
Expert Opin Emerg Drugs 11:621-34. 2006
..A number of possible future directions and challenges for the field are discussed. The treatment of bipolar disorder is unlikely to advance substantially until the causative pathogenetic molecular processes are elucidated...
- Reduced activation to implicit affect induction in euthymic bipolar patients: an fMRI study
Gin S Malhi
School of Psychiatry, University of New South Wales, Sydney, Australia
J Affect Disord 97:109-22. 2007
..To examine whether euthymic bipolar patients engage similar or contrasting brain regions as healthy subjects when responding to implicit affect induction...
- Depression and mania in mixed states
Michael Berk
University of Melbourne, Clinical and Biomedical Sciences-Barwon Health, P.O. Box 281, Geelong, Victoria, Australia
Am J Psychiatry 163:1160. 2006
- The management of bipolar disorder in general practice
Philip B Mitchell
School of Psychiatry, Prince of Wales Hospital, University of New South Wales, Sydney, NSW
Med J Aust 184:566-70. 2006
..There has also been increasing recognition of the contribution of psychological therapies to symptom relief, relapse prevention, optimal function, and quality of life...
- Cognitive compromise in bipolar disorder with chronic cannabis use: cause or consequence?
Catherine M Cahill
University of New South Wales, School of Psychiatry, Sydney, Australia
Expert Rev Neurother 6:591-8. 2006
..The findings are contextualized within bipolar disorder, examining functional outcome...
- A randomized controlled trial of cognitive therapy for bipolar disorder: focus on long-term change
Jillian R Ball
School of Psychiatry, University of New South Wales, Randwick, New South Wales, Australia
J Clin Psychiatry 67:277-86. 2006
..The treatment protocol differed from other published forms of CT for bipolar disorder through the addition of emotive techniques...
- A Brief Measure of Worry Severity (BMWS): personality and clinical correlates of severe worriers
Gemma L Gladstone
School of Psychiatry, University of New South Wales and Mood Disorders Unit, Black Dog Institute, Prince of Wales Hospital, Randwick, NSW 2031, Australia
J Anxiety Disord 19:877-92. 2005
..This study suggests that pathological worry is not only relevant for patients with GAD, but may be an equally detrimental cognitive activity for patients with panic disorder and obsessive-compulsive disorder...
- Pharmacotherapy of bipolar disorder: the role of atypical antipsychotics and experimental strategies
Gin S Malhi
The University of New South Wales Mood Disorders Unit, The Black Dog Institute, The Villa, Prince of Wales Hospital, Randwick, Sydney, NSW 2031, Australia
Hum Psychopharmacol 17:407-12. 2002
..This paper summarizes some of the data regarding these "experimental" therapeutic options, focusing principally on atypical antipsychotics as these are now widely prescribed in the management of bipolar disorder...
