Research Topics
Species | Lai Meng LooiSummaryAffiliation: University of Malaya Country: Malaysia Publications
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Detail Information
Publications
The Pathology Laboratory Act 2007 explainedLai Meng Looi
Department of Pathology, Faculty of Medicine, University Malaya Medical Centre, Kuala Lumpur
Malays J Pathol 30:1-10. 2008..Sincere professional input is thus required to embrace its philosophy, ensure rational and transparent enforcement of legislation, and develop National guidelines for good pathology practices upon which enforcement may be based...- Historical development of the renal histopathology services in MalaysiaLai Meng Looi
Department of Pathology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
Malays J Pathol 31:11-6. 2009..More recently, there has been increasing involvement of renal teams in clinical trials, particularly for lupus nephritis and renal transplant modulation... - p16(INK4a) is a useful marker of human papillomavirus integration allowing risk stratification for cervical malignanciesPhaik Leng Cheah
Department of Pathology, Faculty of Medicine, University of Malaya, Kuala Lumpur
Asian Pac J Cancer Prev 13:469-72. 2012.... - Comparison of telomere length and telomerase activation between breast fibroadenoma and infiltrating ductal carcinoma in Malaysian womenLai Meng Looi
Department of Pathology, Faculty of Medicine, University of Malaya
Asian Pac J Cancer Prev 11:713-6. 2010..05) relative to BNL (2.9 kb). The findings imply that telomere attrition and telomerase activation differ between malignant and benign tumours of the breast and may be important for targeted therapy... - Implications of continued upregulation of p16(INK4a) through the evolution from high-grade squamous intraepithelial lesion to invasive squamous carcinoma of the cervixPhaik Leng Cheah
Department of Pathology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
Malays J Pathol 33:83-7. 2011..Interestingly, the occurrence of HSIL and LSIL in almost the same age group could mean that alteration from episomal to integrated form of HPV may not incur a prolonged incubation period, unlike from HSIL to SCC... - An analysis of predictive biomarkers in routine histopathological reporting of infiltrating ductal breast carcinoma in a tertiary hospital in Malaysia with a focus on limitations and directions for future developmentKean Hooi Teoh
Department of Pathology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
Malays J Pathol 33:35-42. 2011.... - Proliferating cell nuclear antigen (PCNA) activity in hepatocellular carcinoma, benign peri-neoplastic and normal liverKein Seong Mun
Department of Pathology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia
Malays J Pathol 28:73-7. 2006..This is probably related to the malignant nature of HCC and may reflect the uncontrolled proliferation of the neoplastic hepatocytes... 
Unusual finding of endocervical-like mucinous epithelium in continuity with urothelium in endocervicosis of the urinary bladderPhaik Leng Cheah
Department of Pathology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia
Diagn Pathol 6:56. 2011..The patient has remained well and without evidence of disease 18-months following transurethral resection of the lesion...
Human papillomavirus in cervical cancers of MalaysiansPhaik Leng Cheah
Department of Pathology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
J Obstet Gynaecol Res 37:489-95. 2011..With cervical carcinoma remaining the second leading cancer among Malaysian women, it is imperative to clarify the prevalence of human papillomavirus (HPV) in this respect, considering the dearth of local information...- P53 immunohistochemical expression: messages in cervical carcinogenesisPhaik Leng Cheah
Department of Pathology, University of Malaya Medical Centre, Kuala Lumpur, Malaysia
Pathology 34:326-31. 2002..The pattern of p53 expression was studied in pre-invasive and invasive cervical carcinoma in an attempt to clarify its role in cervical carcinogenesis... - Computer-linked image analysis of nuclear area: is there a use in diagnosis and grading of hepatocellular carcinoma?Phaik Leng Cheah
Department of Pathology, University of Malaya Medical Centre, Kuala Lumpur, Malaysia
Malays J Pathol 29:37-40. 2007.... - Telomerase activation in neoplastic cell immortalization and tumour progressionLai Meng Looi
Department of Pathology, Faculty of Medicine, University of Malaya, Malaysia
Malays J Pathol 29:33-5. 2007..These findings support a contributory role for telomerase in tumourigenesis with activation occurring from neoplastic transformation and increasing with tumour progression... - Adjuvant! Online is overoptimistic in predicting survival of Asian breast cancer patientsNirmala Bhoo-Pathy
National Clinical Research Centre, Level 3, Dermatology Block, Kuala Lumpur Hospital, 50586 Jalan Pahang, Kuala Lumpur, Malaysia
Eur J Cancer 48:982-9. 2012..As its prognostic performance has only been validated in high income Caucasian populations, we validated the model in a middle income Asian setting... - Clinical predictors of non-diabetic renal disease and role of renal biopsy in diabetic patients with renal involvement: a single centre reviewYip Boon Chong
Division of Nephrology, Department of Medicine, University Malaya Medical Centre, University of Malaya, Kuala Lumpur, Malaysia
Ren Fail 34:323-8. 2012..Our study aimed to examine the prevalence of NDRD in T2DM and clinical markers for diabetic nephropathy (DN) and NDRD and to determine the role of renal biopsy in T2DM patients and its impact on clinical practice... - Outcome of biliary atresia in Malaysia: a single-centre studyWay Seah Lee
Departments of Paediatrics, University of Malaya Medical Centre, Kuala Lumpur, Malaysia
J Paediatr Child Health 45:279-85. 2009..This study aimed to determine the outcome of the operation of children with biliary atresia (BA) at a tertiary paediatric referral centre in Malaysia... - Mammographic breast glandularity in Malaysian women: data derived from radiographyNoriah Jamal
Department of Radiology, University of Malaya, Kuala Lumpur 59100, Malaysia
AJR Am J Roentgenol 182:713-7. 2004..This study was undertaken to estimate mammographic breast glandularity in Malaysian women from radiographic data... - Tuberculosis or systemic lupus erythematosus? A diagnostic and therapeutic dilemmaAsmah Mohd
Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
Southeast Asian J Trop Med Public Health 34:361-4. 2003..Treatment for the collagen vascular disease with corticosteroids exacerbated the intercurrent infection. The problems in the diagnosis and management of such cases are discussed... - Detection of the human papillomavirus in cervical carcinoma: a comparison between non-isotopic in-situ hybridisation and polymerase chain reaction as methods for detection in formalin-fixed, paraffin-embedded tissuesPhaik Leng Cheah
Department of Pathology, Faculty of Medicine, University of Malaya, Kuala Lumpur
Malays J Pathol 30:37-42. 2008..It thus appears that PCR and NISH can be successfully used to detect HPV in formalin-fixed, paraffin-embedded tissue and in the presence of intact DNA NISH may be as sensitive as PCR... - alpha1-Antitrypsin deficiency is not an important cause of childhood liver diseases in a multi-ethnic Southeast Asian populationWay Seah Lee
Department of Paediatrics, University of Malaya Medical Centre, Kuala Lumpur, Malaysia
J Paediatr Child Health 43:636-9. 2007..We conducted a prospective study to determine the role of alpha1-antitrypsin (alpha1AT) deficiency in the pathogenesis of neonatal cholestasis and other childhood liver diseases in a multi-ethnic Southeast Asian population... - CD44 expression and axillary lymph node metastasis in infiltrating ductal carcinoma of the breastLai Meng Looi
Department of Pathology, Faculty of Medincine, University of Malaya, 50603 Kuala Lumpur, Malaysia
Malays J Pathol 28:83-6. 2006..Our results suggest that CD44 may have a role in the progression of breast cancer and emphasise the need to investigate its interaction with other mechanisms of cancer advancement... - Lessons from the Nipah virus outbreak in MalaysiaLai Meng Looi
Department of Pathology, Faculty of Medicine, University of Malaya, Malaysia
Malays J Pathol 29:63-7. 2007..Environmental mismanagement (such as deforestation and haze) has far-reaching effects, including encroachment of wildlife into human habitats and the introduction of zoonotic infections into domestic animals and humans... - Association of Ki67 with raised transaminases in hepatocellular carcinomaPhaik Leng Cheah
Department of Pathology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
Malays J Pathol 30:103-7. 2008..Thus rising levels of the transaminases could signal a more rapid growth of the tumour and these routinely performed tests can be of prognostic value in management of HCC patients...