Sai Kit Lam

Summary

Affiliation: University of Malaya
Country: Malaysia

Publications

  1. ncbi request reprint Nipah virus encephalitis outbreak in Malaysia
    Sai Kit Lam
    Department of Medical Microbiology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
    Clin Infect Dis 34:S48-51. 2002
  2. ncbi request reprint Isolation of Nipah virus from Malaysian Island flying-foxes
    Kaw Bing Chua
    Department of Medical Microbiology, Faculty of Medicine, University of Malaya, 50603 Lumpur, Kuala, Malaysia
    Microbes Infect 4:145-51. 2002
  3. ncbi request reprint Nipah virus--a potential agent of bioterrorism?
    Sai Kit Lam
    Department of Medical Microbiology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia
    Antiviral Res 57:113-9. 2003
  4. ncbi request reprint Preventive transfusion in Dengue shock syndrome-is it necessary?
    Lucy Chai See Lum
    Department of Pediatrics, University of Malaya Medical Centre, Kuala Lumpur, Malaysia
    J Pediatr 143:682-4. 2003
  5. pmc Nipah virus infection: pathology and pathogenesis of an emerging paramyxoviral zoonosis
    Kum Thong Wong
    University of Malaya, Kuala Lumpur, Malaysia
    Am J Pathol 161:2153-67. 2002
  6. ncbi request reprint Neurovirulence of four encephalitogenic dengue 3 virus strains isolated in Malaysia (1992-1994) is not attributed to their envelope protein
    Mun Yik Fong
    Department of Parasitology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia
    Trans R Soc Trop Med Hyg 98:379-81. 2004
  7. pmc A golden hamster model for human acute Nipah virus infection
    K Thong Wong
    Department of Pathology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia
    Am J Pathol 163:2127-37. 2003
  8. ncbi request reprint Localization of dengue virus in naturally infected human tissues, by immunohistochemistry and in situ hybridization
    Kala Jessie
    Department of Pathology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
    J Infect Dis 189:1411-8. 2004
  9. doi request reprint Preparing for introduction of a dengue vaccine: recommendations from the 1st Dengue v2V Asia-Pacific Meeting
    Sai Kit Lam
    Office of the Vice Chancellor, University of Malaya, Jalan Pantai Baru, 50603 Kuala Lumpur, Malaysia
    Vaccine 29:9417-22. 2011
  10. ncbi request reprint Risk factors for hemorrhage in severe dengue infections
    Lucy Chai See Lum
    Department of Pediatrics, University of Malaya Medical Center, Kuala Lumpur, Malaysia
    J Pediatr 140:629-31. 2002

Detail Information

Publications13

  1. ncbi request reprint Nipah virus encephalitis outbreak in Malaysia
    Sai Kit Lam
    Department of Medical Microbiology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
    Clin Infect Dis 34:S48-51. 2002
    ..The Island flying fox (Pteropus hypomelanus; the fruit bat) is a likely reservoir of this virus. The outbreak in Malaysia was controlled through the culling of >1 million pigs...
  2. ncbi request reprint Isolation of Nipah virus from Malaysian Island flying-foxes
    Kaw Bing Chua
    Department of Medical Microbiology, Faculty of Medicine, University of Malaya, 50603 Lumpur, Kuala, Malaysia
    Microbes Infect 4:145-51. 2002
    ..The isolation of Nipah virus from the Island flying-fox corroborates the serological evidence that it is one of the natural hosts of the virus...
  3. ncbi request reprint Nipah virus--a potential agent of bioterrorism?
    Sai Kit Lam
    Department of Medical Microbiology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia
    Antiviral Res 57:113-9. 2003
    ..From pigs, the virus was also transmitted to other animals such as dogs, cats, and horses. The Nipah virus has the potential to be considered an agent of bioterrorism...
  4. ncbi request reprint Preventive transfusion in Dengue shock syndrome-is it necessary?
    Lucy Chai See Lum
    Department of Pediatrics, University of Malaya Medical Centre, Kuala Lumpur, Malaysia
    J Pediatr 143:682-4. 2003
    ..05) and none in hemorrhage (P=.136) were observed. Preventive transfusions did not produce sustained improvements in the coagulation status in DSS...
  5. pmc Nipah virus infection: pathology and pathogenesis of an emerging paramyxoviral zoonosis
    Kum Thong Wong
    University of Malaya, Kuala Lumpur, Malaysia
    Am J Pathol 161:2153-67. 2002
    ..Infection of endothelial cells and neurons as well as vasculitis and thrombosis seem to be critical to the pathogenesis of this new human disease...
  6. ncbi request reprint Neurovirulence of four encephalitogenic dengue 3 virus strains isolated in Malaysia (1992-1994) is not attributed to their envelope protein
    Mun Yik Fong
    Department of Parasitology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia
    Trans R Soc Trop Med Hyg 98:379-81. 2004
    ..Multiple sequence alignment revealed a high degree of similarity in the E protein of the strains suggesting that neurovirulence of these four encephalitogenic strains is not attributed to this protein...
  7. pmc A golden hamster model for human acute Nipah virus infection
    K Thong Wong
    Department of Pathology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia
    Am J Pathol 163:2127-37. 2003
    ..The golden hamster is proposed as a suitable model for further studies including pathogenesis studies, anti-viral drug testing, and vaccine development against acute Nipah infection...
  8. ncbi request reprint Localization of dengue virus in naturally infected human tissues, by immunohistochemistry and in situ hybridization
    Kala Jessie
    Department of Pathology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
    J Infect Dis 189:1411-8. 2004
    ..Positive-strand viral RNA was detected in the same IHC-positive cells found in the spleen and blood-clot samples. The strong, positive ISH signal in these cells indicated a high copy number of viral RNA, suggesting replication...
  9. doi request reprint Preparing for introduction of a dengue vaccine: recommendations from the 1st Dengue v2V Asia-Pacific Meeting
    Sai Kit Lam
    Office of the Vice Chancellor, University of Malaya, Jalan Pantai Baru, 50603 Kuala Lumpur, Malaysia
    Vaccine 29:9417-22. 2011
    ....
  10. ncbi request reprint Risk factors for hemorrhage in severe dengue infections
    Lucy Chai See Lum
    Department of Pediatrics, University of Malaya Medical Center, Kuala Lumpur, Malaysia
    J Pediatr 140:629-31. 2002
    ..The duration of shock (OR, 2.11; 95% CI, 1.13 to 3.92; P =.019) and low-normal hematocrit at the time of shock (OR, 0.72; 95% CI, 0.55 to 0.95; P =.020) were risk factors of severe hemorrhage...
  11. doi request reprint Challenges in reducing dengue burden; diagnostics, control measures and vaccines
    Sai Kit Lam
    Office of the Vice Chancellor, University of Malaya, Jalan Pantai Baru, 50603, Kuala Lumpur, Malaysia 60 17 8800044 60 37 7259635
    Expert Rev Vaccines 12:995-1010. 2013
    ..Vaccine introduction is a complex process that requires consideration and is discussed here. This review discusses the epidemiology, burden and pathogenesis of dengue, as well as the vaccine candidates currently in clinical development. ..
  12. ncbi request reprint Echovirus 7 associated encephalomyelitis
    Lucy Chai See Lum
    Department of Pediatrics, University of Malaya Medical Center, 50603, Kuala Lumpur, Malaysia
    J Clin Virol 23:153-60. 2002
    ..In 2000, an outbreak of HFMD resulted in the deaths of three children who had rapid cardio-respiratory decompensation and one child who survived a central nervous system infection...
  13. pmc Membrane fusion tropism and heterotypic functional activities of the Nipah virus and Hendra virus envelope glycoproteins
    Katharine N Bossart
    Department of Microbiology and Immunology, Uniformed Services University, Bethesda, Maryland 20814, USA
    J Virol 76:11186-98. 2002
    ..However, no heterotypic activity was observed with envelope glycoproteins of the morbilliviruses Measles virus and Canine distemper virus...