Research Topics
Species | K L GohSummaryAffiliation: University of Malaya Country: Malaysia Publications
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Detail Information
Publications
A second case of diphyllobothriasis in MalaysiaM Rohela
Department of Parasitology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
Southeast Asian J Trop Med Public Health 37:896-8. 2006..The patient had a history of eating raw fish. He was treated with a single dose of praziquantel...
Population structure of Helicobacter pylori among ethnic groups in Malaysia: recent acquisition of the bacterium by the Malay populationChin Yen Tay
School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, NSW 2052, Australia
BMC Microbiol 9:126. 2009..Malaysia is made up of three major ethnic populations, Malay, Chinese and Indian, providing a good population for studying recent H. pylori migration and admixture...- Changing epidemiology of gastroesophageal reflux disease in the Asian-Pacific region: an overviewK L Goh
Department of Medicine, University of Malaya, Kuala Lumpur, Malaysia
J Gastroenterol Hepatol 19:S22-5. 2004..Differing predisposition to GERD among different ethnic groups would mean that such an increase would be more prominent among certain racial groups... - Epidemiology of Helicobacter pylori infection in Malaysia--observations in a multiracial Asian populationK L Goh
Head of Gastroenterology and Hepatology, Department of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia
Med J Malaysia 64:187-92. 2009..Bacterial strain differences between races may be putative but this observation may also indicate gastroprotective environmental factors or a lower genetic susceptibility to develop cancer in the Indians... 
Factors influencing dyspepsia-related consultation: differences between a rural and an urban populationS Mahadeva
Division of Gastroenterology, Department of Medicine, Faculty of Medicine, International Medical University, Kuala Lumpur, Malaysia
Neurogastroenterol Motil 23:846-53. 2011..Dyspepsia is a common, chronic condition but medical consultation rates for symptoms remain variable. We aimed to examine two populations with varied health-care provision to determine predictive factors for dyspepsia-related consultation...- Recurrent abdominal pain and consulting behaviour among children in a rural community in MalaysiaC C Boey
Department of Paediatrics, University of Malaya Medical Center, Kuala Lumpur, Malaysia
Dig Liver Dis 33:140-4. 2001..To look at predictors of consulting behaviour among children with recurrent abdominal pain in a rural community in Malaysia... - Cost-effectiveness of and satisfaction with a Helicobacter pylori "test and treat" strategy compared with prompt endoscopy in young Asians with dyspepsiaS Mahadeva
Division of Gastroenterology, Department of Medicine, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia
Gut 57:1214-20. 2008..To compare a Helicobacter pylori "test and treat" strategy with prompt endoscopy in young Asians with dyspepsia... - Colorectal cancer in Asians: a demographic and anatomic survey in Malaysian patients undergoing colonoscopyK L Goh
Faculty of Medicine, Department of Medicine and Surgery, University of Malaya, Kuala Lumpur, Malaysia
Aliment Pharmacol Ther 22:859-64. 2005..Colorectal cancer is one of the most common forms of gastrointestinal cancer in the world today. In the Asia-Pacific area, it is the fastest emerging gastrointestinal cancer... - Predictors of health-care consultation for recurrent abdominal pain among urban schoolchildren in MalaysiaC C Boey
Department of Paediatrics, University of Malaya Medical Centre, Kuala Lumpur, Malaysia
J Gastroenterol Hepatol 16:154-9. 2001..To look at the predictors of health-care consultation for recurrent abdominal pain among urban schoolchildren in Malaysia... - Time trends in peptic ulcer, erosive reflux oesophagitis, gastric and oesophageal cancers in a multiracial Asian populationK L Goh
Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
Aliment Pharmacol Ther 29:774-80. 2009..Dramatic changes in the prevalence and pattern of gastrointestinal disease has taken place in Asia in recent years... - The significance of life-events as contributing factors in childhood recurrent abdominal pain in an urban community in MalaysiaC C Boey
Department of Paediatrics, University of Malaya Medical Centre, 51900, Kuala Lumpur, Malaysia
J Psychosom Res 51:559-62. 2001..034), change in occupation of an immediate family member (P=.049), examination failure (P=.001) and bullying at school (P=.028). This study strongly suggests that recent stressful life-events are important risk-factors for RAP... - Changing trends in gastrointestinal disease in the Asia-Pacific regionK L Goh
Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
J Dig Dis 8:179-85. 2007..Conversely, an improvement in living conditions has been closely linked to the decrease in GCA and H. pylori prevalence... - The racial cohort phenomenon: seroepidemiology of Helicobacter pylori infection in a multiracial South-East Asian countryK L Goh
Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
Eur J Gastroenterol Hepatol 13:177-83. 2001..The aim of this study is to determine the prevalence rates and risk factors for Helicobacter pylori infection among various races in Malaysia... - Optimal treatment for duodenal ulcer disease: a cost-decision analysis in Malaysian patientsK L Goh
Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur
J Gastroenterol Hepatol 14:32-8. 1999..In conclusion, HP eradication therapy is superior to H2RA maintenance therapy in the treatment of duodenal ulcer disease. Of the HP eradication regimens, OAC is the most cost-effective... - Tumour seeding following percutaneous needle biopsy of hepatocellular carcinomaC S Qua
Division of Gastroenterology, Department of Medicine, University of Malaya, Lembah Pantai, Kuala Lumpur 50503, Malaysia
Singapore Med J 49:e8-11. 2008..We conclude that the need for percutaneous needle biopsy should be critically evaluated in patients presenting with focal hepatic lesions and the role of RFA in treating tumour seeding needs further evaluation... - Gastro-oesophageal reflux disease in chronic laryngitis: prevalence and response to acid-suppressive therapyC S Qua
Division of Gastroenterology, Facultu of Medicine, University of Malaysia, Kuala Lumpur, Malaysia
Aliment Pharmacol Ther 25:287-95. 2007..Gastro-oesophageal reflux is thought to cause chronic laryngitis through laryngopharyngeal reflux. Response of laryngitis to treatment with acid-suppressive therapy supports this causal link... - Ethnic variation, epidemiological factors and quality of life impairment associated with dyspepsia in urban MalaysiaS Mahadeva
Department of Medicine, University of Malaya, Kuala Lumpur, Malaysia
Aliment Pharmacol Ther 31:1141-51. 2010..The role of ethnicity in the development of dyspepsia remains uncertain... - Gastro-oesophageal reflux disease in AsiaK L Goh
Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
J Gastroenterol Hepatol 15:230-8. 2000..More severe and recurrent GORD may require proton pump inhibitors (PPI) or a combination of prokinetic agents and PPI. The choice of long-term treatment may be influenced by the relative costs of prokinetic agents and PPI... - Stressful life events and recurrent abdominal pain in children in a rural district in MalaysiaC C Boey
Department of Paediatrics, University of Malaya Medical Centre, 59100 Kuala Lumpur, Malaysia
Eur J Gastroenterol Hepatol 13:401-4. 2001..The purpose of this study was to look at the correlation between recurrent abdominal pain and the presence of recent stressful life events among schoolchildren in a rural district in Malaysia... - Tolerance and safety to colonoscopy with conscious sedation in Malaysian adultsW T Ma
Division of Gastroenterology, Department of Medicine, University Malaya Medical Centre, Kuala Lumpur
Med J Malaysia 62:313-8. 2007..The current practice of conscious sedation is safe and tolerated well by most adults in our population. However, poor tolerance in a notable minority may have significant clinical implications... - Crohn's disease in adults: observations in a multiracial Asian populationIda Hilmi
Department of Medicine, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia
World J Gastroenterol 12:1435-8. 2006..OR 2.90 (0.95, 9.42) P=0.063]. CONCLUSION: The clinical presentation of CD is similar to the Western experience. Although the overall prevalence is low,there appears to be a clear racial predominance among the Indians... - Co-inheritance of variants/mutations in Malaysian patients with Crohn's diseaseK H Chua
Department of Molecular Medicine, Faculty of Medicine, University of Malaya, Malaysia
Genet Mol Res 11:3115-21. 2012..No other associated mutations or polymorphisms were detected in the two patients who carried the JW1 variant of the CARD15/NOD2 gene... - Gastro-oesophageal reflux disease in 'difficult-to-control' asthma: prevalence and response to treatment with acid suppressive therapyC H Wong
Division of Gastroenterology, Department of Medicine, University of Malaya, Kuala Lumpur, Malaysia
Aliment Pharmacol Ther 23:1321-7. 2006..In these patients the severity of asthma improved significantly with potent acid suppression therapy. This underlines the critical role of acid reflux in this subset of patients with difficult-to-control asthma... - Predictors of recurrent abdominal pain among 9 to 15-year-old urban school-children in MalaysiaC C Boey
Department of Paediatrics, University of Malaya Medical Centre, 59100, Kuala Lumpur, Malaysia
Acta Paediatr 90:353-5. 2001..CONCLUSION: The results of the study show that recurrent abdominal pain was associated with a number of demographic variables, a tendency to have other complaints and a family history of chronic abdominal complaints... - Human leucocyte antigen determinants of susceptibility to Barrett's oesophagus in Asians--a preliminary studyS Rajendra
Division of Gastroenterology, Department of Medicine, Royal Perak College of Medicine, Ipoh, Malaysia
Aliment Pharmacol Ther 21:1377-83. 2005..Characteristic immune profiles have been demonstrated in gastro-oesophageal reflux disease. However, the genetic basis of gastro-oesophageal reflux disease remains unclear... - Chronic pancreatitis: aetiology, epidemiology and clinical presentationK L Goh
Department of Medicine, University Malaya Medical Centre, Kuala Lumpur, Malaysia
Med J Malaysia 60:94-8. 2005..Complications of chronic pancreatitis are important and include pseudocyst formation, bile duct and duodenal strictures... - Update on the management of Helicobacter pylori infection, including drug-resistant organismsK L Goh
Department of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia
J Gastroenterol Hepatol 17:482-7. 2002..It is also important in refractory cases to review the original indication for treatment and determine the importance of the indication... - Demography and clinical course of ulcerative colitis in a multiracial Asian population: a nationwide study from MalaysiaI Hilmi
Department of Medicine, Faculty of Medicine, University of Malaya Medical Center, Kuala Lumpur, Malaysia
J Dig Dis 10:15-20. 2009..To establish the clinical course of ulcerative colitis (UC) in the Malaysian population, comparing the three major ethnic groups: Malay, Chinese and Indian... - Antibiotic prophylaxis tailored to local organisms reduces percutaneous gastrostomy site infectionS Mahadeva
Division of Gastroenterology, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
Int J Clin Pract 63:760-5. 2009..Current recommendations for the choice of antibiotic prophylaxis prior to percutaneous endoscopic gastrostomy (PEG) insertion may not be suitable in all situations... - Appropriateness of colonoscopy using the ASGE guidelines: experience in a large Asian hospitalT H Chan
Division of Gastroenterology and Hepatology, Department of Medicine, University of Malaya, Kuala Lumpur, Malaysia
Chin J Dig Dis 7:24-32. 2006..Furthermore, the rates of positive findings and CRC among the cases with appropriate, inappropriate and unlisted indications did not differ. The ASGE guidelines will need to be modified for Asia to be of practical use... - Histopathological landmarks of hepatocellular carcinoma in MalaysiansP L Cheah
Department of Pathology, University of Malaya Medical Centre, Kuala Lumpur, Malaysia
Malays J Pathol 25:37-43. 2003..Microvascular permeation was shown in 76.2% of cases. On comparison with findings from other studies, no major difference seems to exist between the histological characteristics of our HCC cases and that of other populations... - Appropriateness of colonoscopy in a university hospitalY M Tan
Division of Gastroenterology, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur
Med J Malaysia 59:34-8. 2004..A substantial proportion of colonoscopies (25.4%) was performed for indications not listed in the ASGE guidelines... - Increasing incidence of colorectal cancer in Asia: implications for screeningJoseph J Y Sung
Institute of Digestive Diseases, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong
Lancet Oncol 6:871-6. 2005..Although epidemiological data are scanty, most Asian populations are not aware of the growing problem of colorectal cancer. More work is needed to elucidate the magnitude of the problem in Asia... - CYP2C19 genotype and the PPIs--focus on rabeprazoleP W Y Lim
Eisai Co, Ltd, c o Eisai Asia Regional Services Pte Ltd, Singapore
J Gastroenterol Hepatol 20:S22-8. 2005..This unique feature of rabeprazole complements rabeprazole's fast onset of action, and may lead to profound and consistent inhibition of gastric acid secretion in the treatment of acid-related disorders... - Review article: efficacy and safety of rabeprazole in treating gastroesophageal reflux diseaseP W Y Lim
Eisai Asia Regional Services Pte Ltd, Singapore
J Gastroenterol Hepatol 19:S61-8. 2004..Recent studies have also indicated that rabeprazole on-demand is cost effective in preventing non-erosive reflux disease (NERD) symptom relapse... - Management consensus of inflammatory bowel disease for the Asia-Pacific regionQin Ouyang
Department of Gastroenterology, West China Hospital, Sichuan University, Chengdu, China
J Gastroenterol Hepatol 21:1772-82. 2006.... - Asia Pacific consensus recommendations for colorectal cancer screeningJ J Y Sung
The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, NT, Hong Kong
Gut 57:1166-76. 2008..There is no consensus on whether nurses should be trained to perform endoscopic procedures for screening of colorectal neoplasia...