Research Topics
| Yoke Fun ChanSummaryAffiliation: University of Malaya Country: Malaysia Publications
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Detail Information
Publications
Phylogenetic designation of enterovirus 71 genotypes and subgenotypes using complete genome sequencesYoke Fun Chan
Department of Medical Microbiology, University Malaya, Kuala Lumpur, Malaysia
Infect Genet Evol 10:404-12. 2010..Hence, in the absence of full genome sequences, it is proposed here that a combination of VP1 and 3D RNA polymerase gene sequences be used for initial genotyping of EV-71 isolates...
Emergence of dengue virus type 4 genotype IIA in MalaysiaSazaly AbuBakar
Department of Medical Microbiology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia
J Gen Virol 83:2437-42. 2002..These results suggest that intra-serotypic recombination amongst DENV-4 from independent ancestral lineages may have contributed to the emergence of DENV-4 subgenotype IIA in Malaysia...
Seroprevalence survey of Chikungunya virus in Bagan Panchor, MalaysiaSaid Mas Ayu
Department of Social and Preventive Medicine, Faculty of Medicine, University Malaya, Kuala Lumpur, Malaysia
Am J Trop Med Hyg 83:1245-8. 2010..CHIKV had a high attack rate and considerable clinical impact during the Bagan Panchor outbreak...
Inhibition of enterovirus 71 (EV-71) infections by a novel antiviral peptide derived from EV-71 capsid protein VP1Chee Wah Tan
Department of Medical Microbiology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
PLoS ONE 7:e34589. 2012..The data demonstrated the potential and feasibility of SP40 as a broad spectrum antiviral agent against EV-71...
Epidemiology and seasonality of respiratory viral infections in hospitalized children in Kuala Lumpur, Malaysia: a retrospective study of 27 yearsChee Sieng Khor
Tropical Infectious Diseases Research and Education Centre, Department of Medical Microbiology, Faculty of Medicine, University Malaya, Kuala Lumpur, Malaysia
BMC Pediatr 12:32. 2012..A retrospective study was performed from 1982-2008 to investigate the viral etiology of children (≤ 5 years old) admitted with RTI in a tertiary hospital in Kuala Lumpur, Malaysia...
Enterovirus 71 uses cell surface heparan sulfate glycosaminoglycan as an attachment receptorChee Wah Tan
Department of Medical Microbiology, University Malaya, Kuala Lumpur, Malaysia
J Virol 87:611-20. 2013..Direct binding of EV-71 particles to heparin-Sepharose columns under physiological salt conditions was demonstrated. We conclude that EV-71 infection requires initial binding to heparan sulfate as an attachment receptor...
Genotypic and phenotypic characterization of Chikungunya virus of different genotypes from MalaysiaI Ching Sam
Tropical Infectious Diseases Research and Education Centre, Department of Medical Microbiology, Faculty of Medicine, University Malaya, Kuala Lumpur, Malaysia
PLoS ONE 7:e50476. 2012..To gain insight into these observed epidemiological differences, we compared genotypic and phenotypic characteristics of CHIKV of Asian and ECSA genotypes isolated in Malaysia...
Chikungunya virus of Asian and Central/East African genotypes in MalaysiaI Ching Sam
Tropical Infectious Diseases Research and Education Centre, Department of Medical Microbiology, Faculty of Medicine, University Malaya, Kuala Lumpur, Malaysia
J Clin Virol 46:180-3. 2009..In Malaysia, limited CHIKV outbreaks of the endemic Asian and imported Central/East African genotypes were reported in 1998 and 2006. Since April 2008, an unprecedented nationwide outbreak has affected Malaysia...
Multisensitive community-acquired methicillin-resistant Staphylococcus aureus infections in MalaysiaI Ching Sam
Department of Medical Microbiology, Faculty of Medicine, University Malaya, 50603 Kuala Lumpur, Malaysia
Diagn Microbiol Infect Dis 62:437-9. 2008..There was considerable clonal diversity, with both pandemic and novel multilocus sequence types detected. CA-MRSA rates appear to be increasing in our hospital, warranting close surveillance...
Enterovirus 71 infection induces apoptosis in Vero cellsYoke Fun Chan
Department of Medical Microbiology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia
Malays J Pathol 25:29-35. 2003..The induction, however, requires high level of HEV71 infectivity and the presence of live virus particles, suggesting the need for the presence of specific viral proteins for apoptosis to occur...
Clinical features of Malaysian children hospitalized with community-acquired seasonal influenzaI Ching Sam
Tropical Infectious Diseases Research and Education Centre, Department of Medical Microbiology, Faculty of Medicine, University Malaya, Kuala Lumpur, Malaysia
Int J Infect Dis 14:e36-40. 2010..The aim of this study was to describe the clinical features and seasonal pattern of influenza in children hospitalized in Malaysia, and to identify predictors of severe disease...
