Hany Ariffin

Summary

Affiliation: University of Malaya
Country: Malaysia

Publications

  1. ncbi request reprint Treating childhood acute myeloid leukaemia with the AML-BFM-83 protocol: experience in a developing country
    L L Chan
    Department of Paediatrics, University Malaya Medical Centre, Lembah Pantai, Kuala Lumpur, Malaysia
    Br J Haematol 126:799-805. 2004
  2. pmc Comparable frequency of BRCA1, BRCA2 and TP53 germline mutations in a multi-ethnic Asian cohort suggests TP53 screening should be offered together with BRCA1/2 screening to early-onset breast cancer patients
    Daphne S C Lee
    Cancer Research Initiatives Foundation, Sime Darby Medical Centre, 1 Jalan SS12 1A, Subang Jaya, 47500 Selangor, Malaysia
    Breast Cancer Res 14:R66. 2012
  3. doi request reprint GATA1 mutations in patients with down syndrome and acute megakaryoblastic leukaemia do not always confer a good prognosis
    Hany Ariffin
    Department of Paediatrics, University of Malaya Medical Centre, Kuala Lumpur, Malaysia
    Pediatr Blood Cancer 53:108-11. 2009
  4. doi request reprint Li-Fraumeni syndrome in a Malaysian kindred
    Hany Ariffin
    Pediatric Hematology Oncology Unit, Department of Pediatrics, University of Malaya Medical Center, Kuala Lumpur, Malaysia
    Cancer Genet Cytogenet 186:49-53. 2008
  5. ncbi request reprint Evaluation of two short tandem repeat multiplex systems for post-haematopoietic stem cell transplantation chimerism analysis
    H Ariffin
    Department of Paediatrics, University of Malaya Medical Centre, Lembah Pantai, Kuala Lumpur 50603, Malaysia
    Singapore Med J 48:333-7. 2007
  6. ncbi request reprint Cefepime monotherapy for treatment of febrile neutropenia in children
    Hany Ariffin
    Department of Paediatrics, University of Malaya Medical Centre, Kuala Lumpur, Malaysia
    J Paediatr Child Health 42:781-4. 2006
  7. ncbi request reprint Secondary B-cell acute lymphoblastic leukemia following Wilms' tumor: clinical and in vitro chemosensitivity studies
    H Ariffin
    Department of Paediatrics, University of Malaya Medical Centre, Kuala Lumpur, Malaysia
    Leuk Lymphoma 46:1233-7. 2005
  8. ncbi request reprint Haemophagocytic lymphohistiocytosis in Malaysian children
    H Ariffin
    Paediatric Haematology Oncology Unit, University of Malaya Medical Centre, Kuala Lumpur, Malaysia
    J Paediatr Child Health 41:136-9. 2005
  9. ncbi request reprint Validation of a multiplex RT-PCR assay for screening significant oncogene fusion transcripts in children with acute lymphoblastic leukaemia
    Hany Ariffin
    Paediatric Haematology Oncology Unit, University of Malaya Medical Centre, 50603 Kuala Lumpur, Malaysia
    Singapore Med J 44:517-20. 2003
  10. ncbi request reprint Antibiotic resistance patterns in nosocomial gram-negative bacterial infections in units with heavy antibiotic usage
    Hany Ariffin
    Department of Paediatrics, University of Malaya Medical Centre, 50603 Kuala Lumpur, Malaysia
    J Trop Pediatr 50:26-31. 2004

Collaborators

  • I Ching Sam
  • Pierre Hainaut
  • David S Millar
  • L L Chan
  • Rina Karunakaran
  • L Iyer
  • N Parasakthi
  • P J Kelly
  • Nazneen Rahman
  • S Yetgin
  • Marc D Tischkowitz
  • C G Mathew
  • Bina S Menon
  • D N Cooper
  • L A Chong
  • Siti Sarah Daud
  • Kamariah Ibrahim
  • Daphne S C Lee
  • Lee Ai Chong
  • Sze Yee Chong
  • Shanti RamaChandran
  • Shirley Kow Yin Kham
  • Sarah Reid
  • Cecilia Sze Kwok
  • Meow Keong Thong
  • Nur Aishah Mohd Taib
  • Soo Hwang Teo
  • Sook Yee Yoon
  • Kavitta Sivanandan
  • Peter Kang
  • Lai Meng Looi
  • In Nee Kang
  • Cheng Har Yip
  • Kin Fah Chin
  • Lelamekala Vengidasan
  • Soo Sin Choong
  • Te Chih Liu
  • Yeow Liang Seah
  • Yiong Huak Chan
  • Chin Kok Soh
  • Allen Eng Juh Yeoh
  • Allen E Yeoh
  • Poh Lin Tan
  • Marcel Freund
  • Heidemarie Neitzel
  • Sheila Seal
  • Karen Barker
  • Helmut Hanenberg
  • Reinhard Kalb
  • Francis P Lach
  • Sat Dev Batish
  • Kornelia Neveling
  • Melanie Wurm
  • Arleen D Auerbach
  • Detlev Schindler
  • Sandra Hanks
  • P Josephine
  • Hai Peng Lin
  • Allen Eng Yeoh
  • Shirley Kow Kham
  • Thuan Chong Quah

Detail Information

Publications29

  1. ncbi request reprint Treating childhood acute myeloid leukaemia with the AML-BFM-83 protocol: experience in a developing country
    L L Chan
    Department of Paediatrics, University Malaya Medical Centre, Lembah Pantai, Kuala Lumpur, Malaysia
    Br J Haematol 126:799-805. 2004
    ....
  2. pmc Comparable frequency of BRCA1, BRCA2 and TP53 germline mutations in a multi-ethnic Asian cohort suggests TP53 screening should be offered together with BRCA1/2 screening to early-onset breast cancer patients
    Daphne S C Lee
    Cancer Research Initiatives Foundation, Sime Darby Medical Centre, 1 Jalan SS12 1A, Subang Jaya, 47500 Selangor, Malaysia
    Breast Cancer Res 14:R66. 2012
    ....
  3. doi request reprint GATA1 mutations in patients with down syndrome and acute megakaryoblastic leukaemia do not always confer a good prognosis
    Hany Ariffin
    Department of Paediatrics, University of Malaya Medical Centre, Kuala Lumpur, Malaysia
    Pediatr Blood Cancer 53:108-11. 2009
    ..These patients had high expression levels of cytidine deaminase mRNA transcripts. We speculate that other factors can affect overall outcome in patients with DS-AMKL irrespective of the presence of GATA1 mutations...
  4. doi request reprint Li-Fraumeni syndrome in a Malaysian kindred
    Hany Ariffin
    Pediatric Hematology Oncology Unit, Department of Pediatrics, University of Malaya Medical Center, Kuala Lumpur, Malaysia
    Cancer Genet Cytogenet 186:49-53. 2008
    ..Sequencing of TP53 in the father and two other asymptomatic siblings revealed wild-type TP53. To our knowledge, this is a first report of a Li-Fraumeni syndrome family in Southeast Asia...
  5. ncbi request reprint Evaluation of two short tandem repeat multiplex systems for post-haematopoietic stem cell transplantation chimerism analysis
    H Ariffin
    Department of Paediatrics, University of Malaya Medical Centre, Lembah Pantai, Kuala Lumpur 50603, Malaysia
    Singapore Med J 48:333-7. 2007
    ..The present study aims to identify suitable STR markers for patient-donor pairs of predominantly Malay and Chinese ethnicity using two commercially-available forensic kits...
  6. ncbi request reprint Cefepime monotherapy for treatment of febrile neutropenia in children
    Hany Ariffin
    Department of Paediatrics, University of Malaya Medical Centre, Kuala Lumpur, Malaysia
    J Paediatr Child Health 42:781-4. 2006
    ..We prospectively evaluated the efficacy and safety of cefepime monotherapy in our population of paediatric cancer patients with febrile neutropenia...
  7. ncbi request reprint Secondary B-cell acute lymphoblastic leukemia following Wilms' tumor: clinical and in vitro chemosensitivity studies
    H Ariffin
    Department of Paediatrics, University of Malaya Medical Centre, Kuala Lumpur, Malaysia
    Leuk Lymphoma 46:1233-7. 2005
    ....
  8. ncbi request reprint Haemophagocytic lymphohistiocytosis in Malaysian children
    H Ariffin
    Paediatric Haematology Oncology Unit, University of Malaya Medical Centre, Kuala Lumpur, Malaysia
    J Paediatr Child Health 41:136-9. 2005
    ..To study the clinical presentation, therapy and outcome of children diagnosed with both primary and secondary haemophagocytic lymphohistiocytosis (HLH) at the University of Malaya Medical Centre...
  9. ncbi request reprint Validation of a multiplex RT-PCR assay for screening significant oncogene fusion transcripts in children with acute lymphoblastic leukaemia
    Hany Ariffin
    Paediatric Haematology Oncology Unit, University of Malaya Medical Centre, 50603 Kuala Lumpur, Malaysia
    Singapore Med J 44:517-20. 2003
    ..Multiplex RT-PCR assay is an effective, sensitive, accurate and cost-effective diagnostic tool which can improve our ability to accurately and rapidly risk-stratify patients with childhood ALL...
  10. ncbi request reprint Antibiotic resistance patterns in nosocomial gram-negative bacterial infections in units with heavy antibiotic usage
    Hany Ariffin
    Department of Paediatrics, University of Malaya Medical Centre, 50603 Kuala Lumpur, Malaysia
    J Trop Pediatr 50:26-31. 2004
    ..The carbapenems and quinolones remain useful agents in the management of patients admitted to these units...
  11. ncbi request reprint Prenatal exclusion of severe factor VII deficiency
    Hany Ariffin
    University of Malaya Medical Center, Kuala Lumpur, Malaysia
    J Pediatr Hematol Oncol 25:418-20. 2003
    ..Our experience with the family reported here further supports the conclusion that mutation-specific detection is reliable in the prenatal exclusion of severe bleeding disorders...
  12. doi request reprint Microfluidic chip-based assay for post-hematopoietic stem cell transplantation chimerism monitoring using polymorphic tandem repeat markers
    Siti Sarah Daud
    Paediatric Haematology Oncology Unit, University of Malaya Medical Centre, 50603 Kuala Lumpur, Malaysia
    Anal Biochem 397:181-5. 2010
    ..Quantitative monitoring of post-HSCT chimerism status using microfluidic electrophoresis is a useful tool for both large- and small-scale post-HSCT chimerism centers...
  13. ncbi request reprint Rapid detection of prognostically important childhood acute lymphoblastic leukemia chimeric transcripts using multiplex SYBR green real-time reverse transcription PCR
    Kamariah Ibrahim
    Department of Paediatrics, University of Malaya, 59100 Kuala Lumpur, Malaysia
    Ann Clin Lab Sci 38:338-43. 2008
    ..Validation of the assay was based on conventional karyotyping results. This new assay provides a rapid, sensitive, and accurate detection method for prognostically important transcripts in childhood ALL...
  14. doi request reprint Clinical features of Malaysian children hospitalized with community-acquired seasonal influenza
    I Ching Sam
    Tropical Infectious Diseases Research and Education Centre, Department of Medical Microbiology, Faculty of Medicine, University Malaya, Kuala Lumpur, Malaysia
    Int J Infect Dis 14:e36-40. 2010
    ..The aim of this study was to describe the clinical features and seasonal pattern of influenza in children hospitalized in Malaysia, and to identify predictors of severe disease...
  15. ncbi request reprint Epidemiology and molecular characterization of nosocomially transmitted multidrug-resistant Klebsiella pneumoniae
    N Parasakthi
    Department of Medical Microbiology, University of Malaya Medical Centre, Kuala Lumpur, Malaysia
    Int J Infect Dis 4:123-8. 2000
    ....
  16. ncbi request reprint Single-daily ceftriaxone plus amikacin versus thrice-daily ceftazidime plus amikacin as empirical treatment of febrile neutropenia in children with cancer
    H Ariffin
    Department of Paediatrics, University of Malaya Medical Centre, Kuala Lumpur, Malaysia
    J Paediatr Child Health 37:38-43. 2001
    ..The purpose of this study was to evaluate the efficacy, safety, tolerance and costs of single-daily ceftriaxone plus amikacin versus thrice-daily dose of ceftazidime plus amikacin...
  17. ncbi request reprint A rare X-linked inherited mucocutaneous syndrome in two siblings
    L A Chong
    Department of Paediatrics, Faculty of Medicine, Universiti of Malaya, 50603 Kuala Lumpur
    Med J Malaysia 64:327-9. 2009
    ..Genetic studies of our patient demonstrated the presence of a DKC1 mutation and confirmed our diagnosis. Further genetic screening revealed that his mother and one of his four sisters are heterozygous for the same mutation...
  18. ncbi request reprint Ceftazidime-resistant Klebsiella pneumoniae bloodstream infection in children with febrile neutropenia
    H Ariffin
    Department of Paediatrics and Department of Medical Microbiology, University of Malaya, Kuala Lumpur, Malaysia
    Int J Infect Dis 4:21-5. 2000
    ..pneumoniae (CSKP) bacteremia...
  19. ncbi request reprint Malignant myeloid transformation in a child with severe congenital neutropenia (Kostmann's syndrome)
    L A Chong
    Department of Paediatrics, University of Malaya Medical Centre, Kuala Lumpur
    Med J Malaysia 61:236-8. 2006
    ..The role of G-CSF in the pathogenesis of her malignant transformation to AML is complicated as this disorder has a propensity for myelodysplasia or AML as part of its natural history...
  20. ncbi request reprint Surveillance study of bacteraemic episodes in febrile neutropenic children
    H Ariffin
    Department of Paediatrics, University of Malaya Medical Centre, Kuala Lumpur, Malaysia
    Int J Clin Pract 56:237-40. 2002
    ..A change to our current choice of empirical antibiotics for FN, comprising ceftazidime/ceftriaxone and amikacin appears necessary because of the relatively high resistance rates found...
  21. ncbi request reprint Ethnic differences in the frequency of subtypes of childhood acute lymphoblastic leukemia: results of the Malaysia-Singapore Leukemia Study Group
    Hany Ariffin
    Department of Paediatrics, University of Malaya Medical Centre, Kuala Lumpur, Malaysia
    J Pediatr Hematol Oncol 29:27-31. 2007
    ..Comprehensive subgrouping of childhood ALL may reveal interesting population frequency differences of the various subtypes, their risk factors and hopefully, its etiology...
  22. doi request reprint Secondary acute myeloid leukemia after etoposide therapy for haemophagocytic lymphohistiocytosis
    Shanti RamaChandran
    Department of Paediatrics, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
    Pediatr Blood Cancer 53:488-90. 2009
    ....
  23. doi request reprint Accurate prediction of the needle depth required for successful lumbar puncture
    Sze Yee Chong
    Department of Pediatrics, University of Malaya, Kuala Lumpur 50603, Malaysia
    Am J Emerg Med 28:603-6. 2010
    ..The aim of this study is to formulate an accurate estimate of the spinal needle depth for a successful lumbar puncture in pediatric patients...
  24. ncbi request reprint Providing a cure for beta thalassaemia major
    L L Chan
    Department of Paediatrics, Faculty of Medicine, University of Malaya, Lembah Pantai, Kuala Lumpur
    Med J Malaysia 56:435-40. 2001
    ..Of 38 Malaysian children who underwent bone marrow or cord blood transplantations using matched sibling donors, 29 (76%) are now cured...
  25. ncbi request reprint Chemoreduction for intraocular retinoblastoma in Malaysia
    Bina Sharine Menon
    Paediatric Unit, Universiti Putra Malaysia, General Hospital Kuala Lumpur, Jalan Masjid, Kuala Lumpur 50586, Malaysia
    J Pediatr Hematol Oncol 29:2-4. 2007
    ..In conclusion, 4 cycles of chemoreduction achieved a durable complete response in only 12% of eyes. Chemoreduction is feasible in Malaysia but requires good patient compliance and close follow-up...
  26. ncbi request reprint Biallelic mutations in PALB2 cause Fanconi anemia subtype FA-N and predispose to childhood cancer
    Sarah Reid
    Section of Cancer Genetics, Institute of Cancer Research, Sutton, Surrey SM2 5NG, UK
    Nat Genet 39:162-4. 2007
    ....
  27. doi request reprint Thiopurine S-methyltransferase activity in three major Asian populations: a population-based study in Singapore
    Shirley Kow Yin Kham
    Department of Paediatrics, National University of Singapore, and Department of Haematology Oncology, National University Hospital, Singapore City, Republic of Singapore
    Eur J Clin Pharmacol 64:373-9. 2008
    ..We studied the TPMT phenotype in three major Asian ethnic groups in Singapore, namely the Chinese (Ch), Malays (Mal) and Indians (Ind), with the aim of carrying out a comprehensive survey of the distribution of TPMT activity in Asians...
  28. ncbi request reprint Minimal residual disease (MRD) measurement as a tool to compare the efficacy of chemotherapeutic drug regimens using Escherichia Coli-asparaginase or Erwinia-asparaginase in childhood acute lymphoblastic leukemia (ALL)
    Cecilia Sze Kwok
    Division of Haematology Oncology, Department of Paediatrics, National University of Singapore, Singapore, Singapore
    Pediatr Blood Cancer 47:299-304. 2006
    ..We utilized MRD to compare the efficacy of Erwinia-asparaginase (Erwinia-asp) and E. coli-asparaginase (E. coli-asp) during induction therapy for childhood ALL...
  29. ncbi request reprint Surveillance blood counts for early detection of relapse in acute lymphoblastic leukemia
    Hany Ariffin
    Pediatr Blood Cancer 45:229. 2005