Rajesh Ramasamy

Summary

Affiliation: Universiti Putra Malaysia
Country: Malaysia

Publications

  1. doi request reprint The immunosuppressive effects of human bone marrow-derived mesenchymal stem cells target T cell proliferation but not its effector function
    Rajesh Ramasamy
    Department of Pathology, Immunology Unit, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Selangor, Malaysia
    Cell Immunol 251:131-6. 2008
  2. ncbi request reprint Elevated neutrophil respiratory burst activity in essential hypertensive patients
    Rajesh Ramasamy
    Immunology Laboratory, Department of Pathology, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Malaysia
    Cell Immunol 263:230-4. 2010
  3. pmc Colostrum supplementation protects against exercise-induced oxidative stress in skeletal muscle in mice
    Mahenderan Appukutty
    Faculty of Sports Science and Recreation, University Technology MARA, Shah Alam 40450, Kuala Lumpur, Malaysia
    BMC Res Notes 5:649. 2012
  4. doi request reprint Basic fibroblast growth factor modulates cell cycle of human umbilical cord-derived mesenchymal stem cells
    R Ramasamy
    Immunology Laboratory, Universiti Putra Malaysia, Malaysia
    Cell Prolif 45:132-9. 2012
  5. doi request reprint Bone marrow-derived mesenchymal stem cells modulate BV2 microglia responses to lipopolysaccharide
    Yin Yin Ooi
    Immunology Laboratory, Department of Pathology, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400UPM Serdang, Selangor, Malaysia
    Int Immunopharmacol 10:1532-40. 2010
  6. doi request reprint Mesenchymal stem cells of human placenta and umbilical cord suppress T-cell proliferation at G0 phase of cell cycle
    Shalini Vellasamy
    Immunology Laboratory, Universiti Putra Malaysia, Serdang, Selangor, Malaysia
    Cell Biol Int 37:250-6. 2013
  7. doi request reprint Human umbilical cord blood-derived mesenchymal stem cells (hUCB-MSC) inhibit the proliferation of K562 (human erythromyeloblastoid leukaemic cell line)
    Malini Fonseka
    Immunology Laboratory, Department of Pathology, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia
    Cell Biol Int 36:793-801. 2012
  8. pmc Advancements in reprogramming strategies for the generation of induced pluripotent stem cells
    Mei I Lai
    Department of Pathology, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400, Serdang UPM, Selangor, Malaysia
    J Assist Reprod Genet 28:291-301. 2011
  9. doi request reprint Generation of mesenchymal stem cell from human umbilical cord tissue using a combination enzymatic and mechanical disassociation method
    Chih Kong Tong
    Department of Pathology, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, UPM Serdang, Selangor, Malaysia
    Cell Biol Int 35:221-6. 2011
  10. doi request reprint Immunomodulatory activity of polyphenols derived from Cassia auriculata flowers in aged rats
    Cini M John
    Department of Pathology, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Selangor, Malaysia
    Cell Immunol 271:474-9. 2011

Collaborators

  • Sharmili Vidyadaran
  • Maha Abdullah
  • Elizabeth George
  • Syahril Abdullah
  • Asmah Rahmat
  • Hossein Hosseinkhani
  • Francesco Dazzi
  • H F Seow
  • Shalini Vellasamy
  • Pratheep Sandrasaigaran
  • Yin Yin Ooi
  • Chih Kong Tong
  • Shi Wei Tan
  • Mansooreh Sadat Mojani
  • Mahenderan Appukutty
  • Malini Fonseka
  • Boon Chong Tan
  • Zul atfi Rahmat
  • Cini M John
  • Maryam Maqbool
  • Mei I Lai
  • Loh Su Peng
  • Vahid Hosseinpour Sarmadi
  • Shinsmon Jose
  • Ammu Kutty Radhakrishnan
  • Nagaraja Haleagrahara
  • Abu Bakar Abdul Majeed
  • Poh Bee Koon
  • Kalavathy Ramasamy
  • Mohd Ismail Noor
  • Nik Shanita Safii
  • Karuthan Chinna
  • Norshariza Nordin
  • Rozita Rosli
  • Abhi Veerakumarasivam
  • Wai Yeng Wendy-Yeo
  • Aishah Adam
  • Hemavathy Subramaiam
  • Daud Ahmad Israf

Detail Information

Publications21

  1. doi request reprint The immunosuppressive effects of human bone marrow-derived mesenchymal stem cells target T cell proliferation but not its effector function
    Rajesh Ramasamy
    Department of Pathology, Immunology Unit, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Selangor, Malaysia
    Cell Immunol 251:131-6. 2008
    ..For this reason, they have the potential to be exploited in the control of unwanted immune responses such as graft versus host disease (GVHD) and autoimmunity...
  2. ncbi request reprint Elevated neutrophil respiratory burst activity in essential hypertensive patients
    Rajesh Ramasamy
    Immunology Laboratory, Department of Pathology, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Malaysia
    Cell Immunol 263:230-4. 2010
    ..In conclusion, the respiratory burst activity of neutrophils is affected by hypertension and their elevated superoxide anions production could be an aggravating factor in hypertension-related complication...
  3. pmc Colostrum supplementation protects against exercise-induced oxidative stress in skeletal muscle in mice
    Mahenderan Appukutty
    Faculty of Sports Science and Recreation, University Technology MARA, Shah Alam 40450, Kuala Lumpur, Malaysia
    BMC Res Notes 5:649. 2012
    ..Total antioxidants, lipid hydroperoxides, xanthine oxidase and super oxide dismutase level was assayed from the homogenate of hind limb skeletal muscle...
  4. doi request reprint Basic fibroblast growth factor modulates cell cycle of human umbilical cord-derived mesenchymal stem cells
    R Ramasamy
    Immunology Laboratory, Universiti Putra Malaysia, Malaysia
    Cell Prolif 45:132-9. 2012
    ..However, production of MSC at sufficient clinical scale remains an issue as in vitro generation of MSC inadequately fulfils the demand with respect to patients...
  5. doi request reprint Bone marrow-derived mesenchymal stem cells modulate BV2 microglia responses to lipopolysaccharide
    Yin Yin Ooi
    Immunology Laboratory, Department of Pathology, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400UPM Serdang, Selangor, Malaysia
    Int Immunopharmacol 10:1532-40. 2010
    ..Collectively, these regulatory effects of MSC on microglia offer insight into the potential moderating properties of MSC on inflammatory responses within the CNS...
  6. doi request reprint Mesenchymal stem cells of human placenta and umbilical cord suppress T-cell proliferation at G0 phase of cell cycle
    Shalini Vellasamy
    Immunology Laboratory, Universiti Putra Malaysia, Serdang, Selangor, Malaysia
    Cell Biol Int 37:250-6. 2013
    ..The anti-proliferative activity of MSC was related to this cell cycle arrest of T-cell. UC-MSC produced a greater inhibition than PLC-MSC in all measured parameters...
  7. doi request reprint Human umbilical cord blood-derived mesenchymal stem cells (hUCB-MSC) inhibit the proliferation of K562 (human erythromyeloblastoid leukaemic cell line)
    Malini Fonseka
    Immunology Laboratory, Department of Pathology, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia
    Cell Biol Int 36:793-801. 2012
    ..The anti-proliferative effect of hUCB-MSC was due to arrest of the growth of K562 in the G0 /G1 phase. The mechanisms underlying increased IL-6 and IL-8 secretion and LAP (latency-associated peptide; TGFβ1) by hUCB-MSC remains unknown. ..
  8. pmc Advancements in reprogramming strategies for the generation of induced pluripotent stem cells
    Mei I Lai
    Department of Pathology, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400, Serdang UPM, Selangor, Malaysia
    J Assist Reprod Genet 28:291-301. 2011
    ....
  9. doi request reprint Generation of mesenchymal stem cell from human umbilical cord tissue using a combination enzymatic and mechanical disassociation method
    Chih Kong Tong
    Department of Pathology, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, UPM Serdang, Selangor, Malaysia
    Cell Biol Int 35:221-6. 2011
    ..The present study demonstrates a new and efficient approach in generating MSC from UC, hence serving as ideal alternative source of mesenchymal stem cell for clinical and research use...
  10. doi request reprint Immunomodulatory activity of polyphenols derived from Cassia auriculata flowers in aged rats
    Cini M John
    Department of Pathology, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Selangor, Malaysia
    Cell Immunol 271:474-9. 2011
    ....
  11. doi request reprint Inhibitory effects of palm α-, γ- and δ-tocotrienol on lipopolysaccharide-induced nitric oxide production in BV2 microglia
    Shi Wei Tan
    Immunology Laboratory, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Malaysia
    Cell Immunol 271:205-9. 2011
    ..Of the isoforms tested, δ-tocotrienol lowered NO levels the most, reducing NO by approximately 50% at 48 h post-LPS treatment (p<.05). None of the tocotrienol doses tested affected microglia viability...
  12. pmc Isolation and characterisation of mesenchymal stem cells derived from human placenta tissue
    Shalini Vellasamy
    Shalini Vellasamy, Pratheep Sandrasaigaran, Sharmili Vidyadaran, Rajesh Ramasamy, Immunology Laboratory, Department of Pathology, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia
    World J Stem Cells 4:53-61. 2012
    ..To explore the feasibility of placenta tissue as a reliable and efficient source for generating mesenchymal stem cells (MSC)...
  13. doi request reprint Human mesenchymal stem cells protect neutrophils from serum-deprived cell death
    Maryam Maqbool
    Immunology Laboratory, Department of Pathology, Universiti Putra Malaysia, Selangor, Malaysia
    Cell Biol Int 35:1247-51. 2011
    ..However, whether this effect is exerted through a specific signalling pathway or confining neutrophils in resting state by MSC requires further investigation...
  14. pmc Immunophenotype and differentiation capacity of bone marrow-derived mesenchymal stem cells from CBA/Ca, ICR and Balb/c mice
    Yin Yin Ooi
    Yin Yin Ooi, Zul atfi Rahmat, Shinsmon Jose, Rajesh Ramasamy, Sharmili Vidyadaran, Immunology Laboratory, Department of Pathology, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 Serdang, Malaysia
    World J Stem Cells 5:34-42. 2013
    ..To assess the capacity to isolate and expand mesenchymal stem cells (MSC) from bone marrow of CBA/Ca, ICR and Balb/c mice...
  15. doi request reprint Gender effect on in vitro lymphocyte subset levels of healthy individuals
    Maha Abdullah
    Immunology Unit, Department of Pathology, Universiti Putra Malaysia, Malaysia
    Cell Immunol 272:214-9. 2012
    ..Our results showed significant gender differences in lymphocyte subsets in cultured conditions. This may affect experimental outcome...
  16. ncbi request reprint Evaluation of metabolic and immunological changes in streptozotocin-nicotinamide induced diabetic rats
    Mansooreh Sadat Mojani
    Department of Nutrition and Dietetics, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Malaysia
    Cell Immunol 289:145-9. 2014
    ..05). This model of diabetic animals may represent some but not all symptoms of human type 2 diabetes...
  17. ncbi request reprint Screening for intermediate and severe forms of thalassaemia in discarded red blood cells: optimization and feasibility
    Elizabeth George
    Dept of Pathology hematology, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Selangor 43400, Malaysia
    Med J Malaysia 66:429-34. 2011
    ..Cord blood with severe and intermediate forms of thalassaemia can be preselected and not stored...
  18. pmc Gene transfer into the lung by nanoparticle dextran-spermine/plasmid DNA complexes
    Syahril Abdullah
    UPM MAKNA Cancer Research Laboratory, Institute of Bioscience, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia
    J Biomed Biotechnol 2010:284840. 2010
    ..The study also showed that there was a clear trend of increasing size of the complexes as the amount of pDNA was increased, where the sizes of the D-SPM/pDNA complexes were within the nanometer range...
  19. doi request reprint Effects of macrophage colony-stimulating factor on microglial responses to lipopolysaccharide and beta amyloid
    Sharmili Vidyadaran
    Immunology Unit, Department of Pathology, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Malaysia
    Cell Immunol 259:105-10. 2009
    ..M-CSF supplementation in BV-2 cells had no effect on nitric oxide (NO) production. Therefore, M-CSF can be considered for improving microglia yield in culture without introducing activation artefacts...
  20. ncbi request reprint Mesenchymal stem cells inhibit dendritic cell differentiation and function by preventing entry into the cell cycle
    Rajesh Ramasamy
    Department of Immunology, Imperial College Faculty of Medicine, London, U K
    Transplantation 83:71-6. 2007
    ..In this study, we investigated the effect of bone marrow MSC on the differentiation and function of peripheral blood monocytes into dendritic cells (DCs)...
  21. ncbi request reprint The role of mesenchymal stem cells in haemopoiesis
    Francesco Dazzi
    Department of Immunology, Faculty of Medicine, Hammersmith Campus, Imperial College London, Du Cane Road, London, UK
    Blood Rev 20:161-71. 2006
    ..Thus, the multipotent capacity of MSC, their role in supporting haemopoiesis, and their immunoregulatory activity make MSC particularly attractive for therapeutic exploitation...