Ho Yi Mak

Summary

Publications

  1. pmc Nuclear cGMP-dependent kinase regulates gene expression via activity-dependent recruitment of a conserved histone deacetylase complex
    Yan Hao
    Stowers Institute for Medical Research, Kansas City, Missouri, USA
    PLoS Genet 7:e1002065. 2011
  2. pmc Lipid droplets as fat storage organelles in Caenorhabditis elegans: Thematic Review Series: Lipid Droplet Synthesis and Metabolism: from Yeast to Man
    Ho Yi Mak
    Stowers Institute for Medical Research, Kansas City, MO 64110, USA
    J Lipid Res 53:28-33. 2012
  3. pmc Lipid droplets as ubiquitous fat storage organelles in C. elegans
    Shaobing O Zhang
    Stowers Institute for Medical Research, 1000 E, 50th Street, Kansas City, MO 64110, USA
    BMC Cell Biol 11:96. 2010
  4. pmc The FATP1-DGAT2 complex facilitates lipid droplet expansion at the ER-lipid droplet interface
    Ningyi Xu
    Stowers Institute for Medical Research, Kansas City, MO 64110, USA
    J Cell Biol 198:895-911. 2012
  5. pmc Genetic and dietary regulation of lipid droplet expansion in Caenorhabditis elegans
    Shaobing O Zhang
    Stowers Institute for Medical Research, Kansas City, MO 64110, USA
    Proc Natl Acad Sci U S A 107:4640-5. 2010
  6. pmc The RDE-10/RDE-11 complex triggers RNAi-induced mRNA degradation by association with target mRNA in C. elegans
    Huan Yang
    Stowers Institute for Medical Research, Kansas City, MO 64110, USA
    Genes Dev 26:846-56. 2012
  7. ncbi request reprint Visualization of lipid droplets in C. elegans by light and electron microscopy
    Ho Yi Mak
    Stowers Institute for Medical Research, Kansas City, Missouri, USA Department of Molecular and Integrative Physiology, University of Kansas Medical Center, Kansas City, Kansas, USA
    Methods Cell Biol 116:39-51. 2013
  8. ncbi request reprint The DEAD box helicase RDE-12 promotes amplification of RNAi in cytoplasmic foci in C. elegans
    Huan Yang
    Stowers Institute for Medical Research, Kansas City, MO 64110, USA Department of Molecular and Integrative Physiology, University of Kansas Medical Center, Kansas City, KS 66160, USA
    Curr Biol 24:832-8. 2014

Collaborators

  • Ying Zhang
  • Shaobing O Zhang
  • Hua Li
  • Huan Yang
  • Ningyi Xu
  • Jim Vallandingham
  • Laurence Florens
  • Yan Hao
  • Philip Shiu
  • Craig P Hunter
  • Sudheer Bobba
  • RONALD A COLE
  • Joel T Haas
  • Robert V Farese
  • Fengli Guo
  • Sean A McKinney
  • Laura Schaefer
  • Kasthuri Kannan
  • Michael P Washburn
  • Winfried Wiegraebe
  • Christopher Seidel
  • Andrew C Box

Detail Information

Publications8

  1. pmc Nuclear cGMP-dependent kinase regulates gene expression via activity-dependent recruitment of a conserved histone deacetylase complex
    Yan Hao
    Stowers Institute for Medical Research, Kansas City, Missouri, USA
    PLoS Genet 7:e1002065. 2011
    ..We also identify transcriptional targets of EGL-4 that carry out discrete components of the physiological response...
  2. pmc Lipid droplets as fat storage organelles in Caenorhabditis elegans: Thematic Review Series: Lipid Droplet Synthesis and Metabolism: from Yeast to Man
    Ho Yi Mak
    Stowers Institute for Medical Research, Kansas City, MO 64110, USA
    J Lipid Res 53:28-33. 2012
    ..Therefore, further studies on lipid droplets in C. elegans promise to yield valuable insights that complement our knowledge gained from yeast, Drosophila, and mammalian systems on cellular and organismal fat storage...
  3. pmc Lipid droplets as ubiquitous fat storage organelles in C. elegans
    Shaobing O Zhang
    Stowers Institute for Medical Research, 1000 E, 50th Street, Kansas City, MO 64110, USA
    BMC Cell Biol 11:96. 2010
    ..In the present study, we seek to provide further evidence on the organelle nature and biophysical properties of fat storage structures in wild-type and mutant C. elegans...
  4. pmc The FATP1-DGAT2 complex facilitates lipid droplet expansion at the ER-lipid droplet interface
    Ningyi Xu
    Stowers Institute for Medical Research, Kansas City, MO 64110, USA
    J Cell Biol 198:895-911. 2012
    ..We propose that the evolutionarily conserved FATP1-DGAT2 complex acts at the ER-LD interface and couples the synthesis and deposition of triglycerides into LDs both physically and functionally...
  5. pmc Genetic and dietary regulation of lipid droplet expansion in Caenorhabditis elegans
    Shaobing O Zhang
    Stowers Institute for Medical Research, Kansas City, MO 64110, USA
    Proc Natl Acad Sci U S A 107:4640-5. 2010
    ..Our results implicate peroxisomal dysfunction in pathologic lipid droplet expansion in animals and illustrate how dietary factors modulate the phenotype of such genetic defects...
  6. pmc The RDE-10/RDE-11 complex triggers RNAi-induced mRNA degradation by association with target mRNA in C. elegans
    Huan Yang
    Stowers Institute for Medical Research, Kansas City, MO 64110, USA
    Genes Dev 26:846-56. 2012
    ..Therefore, the RDE-10/RDE-11 complex is critical for amplifying the exogenous RNAi response. Our work uncovers an essential output of the RNAi pathway in C. elegans...
  7. ncbi request reprint Visualization of lipid droplets in C. elegans by light and electron microscopy
    Ho Yi Mak
    Stowers Institute for Medical Research, Kansas City, Missouri, USA Department of Molecular and Integrative Physiology, University of Kansas Medical Center, Kansas City, Kansas, USA
    Methods Cell Biol 116:39-51. 2013
    ..Additional methods for visualizing lipid droplets by transmission electron microscopy and detection of lipid droplet associated proteins by immunoelectron microscopy are described. ..
  8. ncbi request reprint The DEAD box helicase RDE-12 promotes amplification of RNAi in cytoplasmic foci in C. elegans
    Huan Yang
    Stowers Institute for Medical Research, Kansas City, MO 64110, USA Department of Molecular and Integrative Physiology, University of Kansas Medical Center, Kansas City, KS 66160, USA
    Curr Biol 24:832-8. 2014
    ..Our results suggest that RDE-12 promotes secondary siRNA synthesis by orchestrating the recruitment of RDE-10 and RRF-1 to primary siRNA-targeted mRNA in distinct cytoplasmic compartments...