Ho Yi Mak

Summary

Publications

  1. pmc Lipid droplets as fat storage organelles in Caenorhabditis elegans: Thematic Review Series: Lipid Droplet Synthesis and Metabolism: from Yeast to Man
    Ho Yi Mak
    Stowers Institute for Medical Research, Kansas City, MO 64110, USA
    J Lipid Res 53:28-33. 2012
  2. pmc Lipid droplets as ubiquitous fat storage organelles in C. elegans
    Shaobing O Zhang
    Stowers Institute for Medical Research, 1000 E, 50th Street, Kansas City, MO 64110, USA
    BMC Cell Biol 11:96. 2010
  3. pmc The FATP1-DGAT2 complex facilitates lipid droplet expansion at the ER-lipid droplet interface
    Ningyi Xu
    Stowers Institute for Medical Research, Kansas City, MO 64110, USA
    J Cell Biol 198:895-911. 2012
  4. pmc The RDE-10/RDE-11 complex triggers RNAi-induced mRNA degradation by association with target mRNA in C. elegans
    Huan Yang
    Stowers Institute for Medical Research, Kansas City, MO 64110, USA
    Genes Dev 26:846-56. 2012
  5. pmc Genetic and dietary regulation of lipid droplet expansion in Caenorhabditis elegans
    Shaobing O Zhang
    Stowers Institute for Medical Research, Kansas City, MO 64110, USA
    Proc Natl Acad Sci U S A 107:4640-5. 2010
  6. pmc Nuclear cGMP-dependent kinase regulates gene expression via activity-dependent recruitment of a conserved histone deacetylase complex
    Yan Hao
    Stowers Institute for Medical Research, Kansas City, Missouri, USA
    PLoS Genet 7:e1002065. 2011

Collaborators

  • Ying Zhang
  • Hua Li
  • Shaobing O Zhang
  • Ningyi Xu
  • Fengli Guo
  • Huan Yang
  • Laurence Florens
  • Yan Hao
  • Andrew C Box
  • Rhonda Trimble
  • Sean A McKinney
  • Jim Vallandingham
  • Sudheer Bobba
  • RONALD A COLE
  • Joel T Haas
  • Robert V Farese
  • Winfried Wiegraebe
  • Laura Schaefer
  • Christopher Seidel
  • Kasthuri Kannan
  • Michael P Washburn
  • Johan Le Men
  • Jingyi Yu

Detail Information

Publications6

  1. pmc Lipid droplets as fat storage organelles in Caenorhabditis elegans: Thematic Review Series: Lipid Droplet Synthesis and Metabolism: from Yeast to Man
    Ho Yi Mak
    Stowers Institute for Medical Research, Kansas City, MO 64110, USA
    J Lipid Res 53:28-33. 2012
    ..Therefore, further studies on lipid droplets in C. elegans promise to yield valuable insights that complement our knowledge gained from yeast, Drosophila, and mammalian systems on cellular and organismal fat storage...
  2. pmc Lipid droplets as ubiquitous fat storage organelles in C. elegans
    Shaobing O Zhang
    Stowers Institute for Medical Research, 1000 E, 50th Street, Kansas City, MO 64110, USA
    BMC Cell Biol 11:96. 2010
    ..In the present study, we seek to provide further evidence on the organelle nature and biophysical properties of fat storage structures in wild-type and mutant C. elegans...
  3. pmc The FATP1-DGAT2 complex facilitates lipid droplet expansion at the ER-lipid droplet interface
    Ningyi Xu
    Stowers Institute for Medical Research, Kansas City, MO 64110, USA
    J Cell Biol 198:895-911. 2012
    ..We propose that the evolutionarily conserved FATP1-DGAT2 complex acts at the ER-LD interface and couples the synthesis and deposition of triglycerides into LDs both physically and functionally...
  4. pmc The RDE-10/RDE-11 complex triggers RNAi-induced mRNA degradation by association with target mRNA in C. elegans
    Huan Yang
    Stowers Institute for Medical Research, Kansas City, MO 64110, USA
    Genes Dev 26:846-56. 2012
    ..Therefore, the RDE-10/RDE-11 complex is critical for amplifying the exogenous RNAi response. Our work uncovers an essential output of the RNAi pathway in C. elegans...
  5. pmc Genetic and dietary regulation of lipid droplet expansion in Caenorhabditis elegans
    Shaobing O Zhang
    Stowers Institute for Medical Research, Kansas City, MO 64110, USA
    Proc Natl Acad Sci U S A 107:4640-5. 2010
    ..Our results implicate peroxisomal dysfunction in pathologic lipid droplet expansion in animals and illustrate how dietary factors modulate the phenotype of such genetic defects...
  6. pmc Nuclear cGMP-dependent kinase regulates gene expression via activity-dependent recruitment of a conserved histone deacetylase complex
    Yan Hao
    Stowers Institute for Medical Research, Kansas City, Missouri, USA
    PLoS Genet 7:e1002065. 2011
    ..We also identify transcriptional targets of EGL-4 that carry out discrete components of the physiological response...