R J MacFadyen

Summary

Publications

  1. pmc How often are angiotensin II and aldosterone concentrations raised during chronic ACE inhibitor treatment in cardiac failure?
    R J MacFadyen
    Departments of Clinical Pharmacology and Cardiology, Cardiovascular Research Group, Ninewells Hospital and Medical School, University of Dundee, Dundee DD1 9SY, UK
    Heart 82:57-61. 1999
  2. ncbi request reprint Aldosterone blockade reduces vascular collagen turnover, improves heart rate variability and reduces early morning rise in heart rate in heart failure patients
    R J MacFadyen
    Department of Clinical Pharmacology, University of Dundee, Ninewells Hospital and Medical School, UK
    Cardiovasc Res 35:30-4. 1997
  3. pmc Is there a role for renin profiling in selecting chronic heart failure patients for ACE inhibitor treatment?
    P O Lim
    Cardiovascular Research Group, Department of Clinical Pharmacology and Therapeutics, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK
    Heart 83:257-61. 2000

Collaborators

Detail Information

Publications3

  1. pmc How often are angiotensin II and aldosterone concentrations raised during chronic ACE inhibitor treatment in cardiac failure?
    R J MacFadyen
    Departments of Clinical Pharmacology and Cardiology, Cardiovascular Research Group, Ninewells Hospital and Medical School, University of Dundee, Dundee DD1 9SY, UK
    Heart 82:57-61. 1999
    ..In congestive heart failure (CHF) such failure of hormonal suppression is associated with increased mortality. This study examined how common AII and aldosterone increases are observed during routine clinical practice...
  2. ncbi request reprint Aldosterone blockade reduces vascular collagen turnover, improves heart rate variability and reduces early morning rise in heart rate in heart failure patients
    R J MacFadyen
    Department of Clinical Pharmacology, University of Dundee, Ninewells Hospital and Medical School, UK
    Cardiovasc Res 35:30-4. 1997
    ..Experimental data suggest that aldosterone has harmful effects promoting myocardial fibrosis and disturbing autonomic balance. There has been no evidence of these potential effects in intact man...
  3. pmc Is there a role for renin profiling in selecting chronic heart failure patients for ACE inhibitor treatment?
    P O Lim
    Cardiovascular Research Group, Department of Clinical Pharmacology and Therapeutics, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK
    Heart 83:257-61. 2000
    ..It remains uncertain whether angiotensin converting enzyme (ACE) inhibitors benefit all heart failure patients or just those with renin-angiotensin-aldosterone system (RAAS) activation...