Sean MacEachern

Summary

Publications

  1. pmc An examination of positive selection and changing effective population size in Angus and Holstein cattle populations (Bos taurus) using a high density SNP genotyping platform and the contribution of ancient polymorphism to genomic diversity in Domestic ca
    Sean MacEachern
    Primary Industries Research Victoria, Animal Genetics and Genomics, Attwood, Vic, Australia
    BMC Genomics 10:181. 2009
  2. pmc Phylogenetic reconstruction and the identification of ancient polymorphism in the Bovini tribe (Bovidae, Bovinae)
    Sean MacEachern
    Primary Industries Research Victoria, Animal Genetics and Genomics, Attwood, Vic, Australia
    BMC Genomics 10:177. 2009
  3. pmc Molecular evolution of the Bovini tribe (Bovidae, Bovinae): is there evidence of rapid evolution or reduced selective constraint in Domestic cattle?
    Sean MacEachern
    Primary Industries Research Victoria, Animal Genetics and Genomics, Attwood, Vic, Australia
    BMC Genomics 10:179. 2009
  4. pmc Testing the neutral theory of molecular evolution using genomic data: a comparison of the human and bovine transcriptome
    Sean MacEachern
    Primary Industries Research Victoria, Animal Genetics and Genomics, Attwood VIC 3049, Australia
    Genet Sel Evol 38:321-41. 2006

Detail Information

Publications4

  1. pmc An examination of positive selection and changing effective population size in Angus and Holstein cattle populations (Bos taurus) using a high density SNP genotyping platform and the contribution of ancient polymorphism to genomic diversity in Domestic ca
    Sean MacEachern
    Primary Industries Research Victoria, Animal Genetics and Genomics, Attwood, Vic, Australia
    BMC Genomics 10:181. 2009
    ..We analysed over 7,500 polymorphic single nucleotide polymorphisms (SNP) in beef (Angus) and dairy (Holstein) cattle and outgroup species Bison, Yak and Banteng in an indirect test of inbreeding and positive selection in Domestic cattle...
  2. pmc Phylogenetic reconstruction and the identification of ancient polymorphism in the Bovini tribe (Bovidae, Bovinae)
    Sean MacEachern
    Primary Industries Research Victoria, Animal Genetics and Genomics, Attwood, Vic, Australia
    BMC Genomics 10:177. 2009
    ..A partial phylogenetic reconstruction of 13 extant members of the Bovini tribe (Bovidae, Bovinae) from 15 complete or partially sequenced autosomal genes is presented...
  3. pmc Molecular evolution of the Bovini tribe (Bovidae, Bovinae): is there evidence of rapid evolution or reduced selective constraint in Domestic cattle?
    Sean MacEachern
    Primary Industries Research Victoria, Animal Genetics and Genomics, Attwood, Vic, Australia
    BMC Genomics 10:179. 2009
    ..Elevated rates of dN/dS were further queried to determine if they were the result of positive selection, low effective population size (N(e)) or reduced selective constraint...
  4. pmc Testing the neutral theory of molecular evolution using genomic data: a comparison of the human and bovine transcriptome
    Sean MacEachern
    Primary Industries Research Victoria, Animal Genetics and Genomics, Attwood VIC 3049, Australia
    Genet Sel Evol 38:321-41. 2006
    ..In most cases dN/dS ratios were lower in human-cattle divergence than in common human polymorphism presumably due to differences in the effectiveness of purifying selection between long-term divergence and short-term polymorphism...